Nancy J Wesensten

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine
    Nancy Jo Wesensten
    Department of Neurobiology and Behaviour, Division of Neuropsychiatry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Psychopharmacology (Berl) 159:238-47. 2002
  2. ncbi request reprint Daytime sleep and performance following a zolpidem and melatonin cocktail
    Nancy Jo Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Sleep 28:93-103. 2005
  3. ncbi request reprint Effects of modafinil on cognitive performance and alertness during sleep deprivation
    Nancy J Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Curr Pharm Des 12:2457-71. 2006
  4. ncbi request reprint Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation
    Nancy J Wesensten
    Division of Psychiatry and Neuroscience, Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 14:255-66. 2005
  5. pmc Banking sleep: realization of benefits during subsequent sleep restriction and recovery
    Tracy L Rupp
    Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Sleep 32:311-21. 2009
  6. ncbi request reprint Comparative utility of instruments for monitoring sleepiness-related performance decrements in the operational environment
    Thomas J Balkin
    Department of Behavioral Biology, Division of Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 13:219-27. 2004
  7. ncbi request reprint Caffeine gum minimizes sleep inertia
    Rachel A Newman
    Department of Behavioral Biology, Center for Military Psychiatry and Neurosciences Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Percept Mot Skills 116:280-93. 2013
  8. ncbi request reprint On the importance of countermeasures in sleep and performance models
    Thomas J Balkin
    Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 75:A155-7. 2004
  9. ncbi request reprint Ampakine (CX717) effects on performance and alertness during simulated night shift work
    Nancy J Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 78:937-43. 2007
  10. ncbi request reprint Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study
    Gregory Belenky
    Division of Neuropsychiatry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    J Sleep Res 12:1-12. 2003

Detail Information

Publications20

  1. ncbi request reprint Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine
    Nancy Jo Wesensten
    Department of Neurobiology and Behaviour, Division of Neuropsychiatry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Psychopharmacology (Berl) 159:238-47. 2002
    ..The performance and alertness effects of modafinil were evaluated to determine whether modafinil should replace caffeine for restoring performance and alertness during total sleep deprivation in otherwise healthy adults...
  2. ncbi request reprint Daytime sleep and performance following a zolpidem and melatonin cocktail
    Nancy Jo Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Sleep 28:93-103. 2005
    ..At effective doses, zolpidem induces sleep but also impairs performance. Combining melatonin with low-dose zolpidem may promote daytime sleep without exacerbating performance impairments seen with high-dose zolpidem alone...
  3. ncbi request reprint Effects of modafinil on cognitive performance and alertness during sleep deprivation
    Nancy J Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Curr Pharm Des 12:2457-71. 2006
    ..Such studies would be comprised of direct, head-to-head comparisons among various stimulants across a range of dosages...
  4. ncbi request reprint Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation
    Nancy J Wesensten
    Division of Psychiatry and Neuroscience, Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 14:255-66. 2005
    ..The duration of these benefits vary in accordance with the different elimination rates of the drugs. Whether caffeine, dextroamphetamine, and modafinil differentially restore executive functions during sleep deprivation remains unclear...
  5. pmc Banking sleep: realization of benefits during subsequent sleep restriction and recovery
    Tracy L Rupp
    Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Sleep 32:311-21. 2009
    ..Determine whether sleep extension (a) improves alertness and performance during subsequent sleep restriction and (b) impacts the rate at which alertness and performance are restored by post-restriction recovery sleep...
  6. ncbi request reprint Comparative utility of instruments for monitoring sleepiness-related performance decrements in the operational environment
    Thomas J Balkin
    Department of Behavioral Biology, Division of Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 13:219-27. 2004
    ....
  7. ncbi request reprint Caffeine gum minimizes sleep inertia
    Rachel A Newman
    Department of Behavioral Biology, Center for Military Psychiatry and Neurosciences Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Percept Mot Skills 116:280-93. 2013
    ..post-awakening. Caffeinated gum is a viable means of rapidly attenuating sleep inertia, suggesting that the adenosine receptor system is involved in sleep maintenance...
  8. ncbi request reprint On the importance of countermeasures in sleep and performance models
    Thomas J Balkin
    Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 75:A155-7. 2004
  9. ncbi request reprint Ampakine (CX717) effects on performance and alertness during simulated night shift work
    Nancy J Wesensten
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 78:937-43. 2007
    ..The potential performance and objective alertness-enhancing effects of CX717 (a novel cognitive enhancer currently being tested in Phase II clinical trials) were evaluated using a simulated night shift work paradigm...
  10. ncbi request reprint Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study
    Gregory Belenky
    Division of Neuropsychiatry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    J Sleep Res 12:1-12. 2003
    ..These adaptive changes are hypothesized to restrict brain operational capacity and to persist for several days after normal sleep duration is restored, delaying recovery...
  11. ncbi request reprint Impaired decision making following 49 h of sleep deprivation
    William D S Killgore
    Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 15:7-13. 2006
    ....
  12. doi request reprint Sleep history affects task acquisition during subsequent sleep restriction and recovery
    Tracy L Rupp
    Department of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 19:289-97. 2010
    ..In sum, 1 week of sleep extension improved resilience during subsequent sleep restriction and facilitated task acquisition during recovery, demonstrating that nightly sleep duration exerts long-term (days, weeks) effects...
  13. doi request reprint Sleep loss and sleepiness: current issues
    Thomas J Balkin
    Department of Behavioral Biology, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Chest 134:653-60. 2008
    ..Individual differences in habitual sleep duration appear to be a trait-like characteristic that is determined by several factors, including genetic polymorphisms...
  14. ncbi request reprint Age and individual variability in performance during sleep restriction
    Paul D Bliese
    Department of Behavioral Biology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 15:376-85. 2006
    ....
  15. ncbi request reprint Automated Neuropsychological Assessment Metrics: repeated assessment with two military samples
    Stephanie E Eonta
    Naval Medical Research Center, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 82:34-9. 2011
    ..of this report was to evaluate performance following multiple administrations of the ANAM4 TBI Battery: does performance in a repeated measures paradigm constitute a stable, interpretable indication of baseline neurocognitive ability?..
  16. ncbi request reprint Modafinil vs. caffeine: effects on fatigue during sleep deprivation
    Nancy Jo Wesensten
    Department of Behavioral Biology, Division of Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Aviat Space Environ Med 75:520-5. 2004
    ..The extent to which modafinil and caffeine reverse fatigue effects (defined as performance decrements with time on task) during total sleep deprivation was investigated...
  17. doi request reprint PER3 and ADORA2A polymorphisms impact neurobehavioral performance during sleep restriction
    Tracy L Rupp
    Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Sleep Res 22:160-5. 2013
    ..Given the small sample size these results are preliminary and require replication...
  18. pmc Trait-like vulnerability to total and partial sleep loss
    Tracy L Rupp
    Behavioral Biology Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Sleep 35:1163-72. 2012
    ..To determine the extent to which individual differences in vulnerability to total sleep deprivation also reflect individual differences in vulnerability to multiple nights of sleep restriction...
  19. ncbi request reprint The process of awakening: a PET study of regional brain activity patterns mediating the re-establishment of alertness and consciousness
    Thomas J Balkin
    Department of Behavioral Biology, Walter Reed Army Institute of Research, Washington, DC 20307 5100, USA
    Brain 125:2308-19. 2002
    ..Conversely, stable post-awakening correlations--such as those found between the anterior cingulate cortex (ACC) and most other brain regions--may denote the pattern of functional connectivity that underlies consciousness itself...
  20. doi request reprint A new metric for quantifying performance impairment on the psychomotor vigilance test
    Srinivasan Rajaraman
    DoD Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, US Army Medical Research and Materiel Command, Fort Detrick, MD 21702, USA
    J Sleep Res 21:659-74. 2012
    ..Based on these findings, and that the new metric considers performance changes based on the entire set of responses relative to a baseline, we conclude that it provides a number of potential advantages over the traditional PVT metrics...