Amy C Shurtleff

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi Standardization of the filovirus plaque assay for use in preclinical studies
    Amy C Shurtleff
    Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA
    Viruses 4:3511-30. 2012
  2. ncbi The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment
    Amy C Shurtleff
    Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702, USA
    Viruses 4:3932-51. 2012
  3. ncbi Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design
    Amy C Shurtleff
    U S Army Medical Research Institute of Infectious Diseases, Integrated Toxicology Division, Fort Detrick, 1425 Porter Street, Frederick, MD 21702, USA
    Expert Opin Drug Discov 7:935-54. 2012
  4. ncbi Advanced morpholino oligomers: a novel approach to antiviral therapy
    Travis K Warren
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21769, USA
    Antiviral Res 94:80-8. 2012
  5. ncbi Nonhuman primates as models for the discovery and development of ebolavirus therapeutics
    Amy C Shurtleff
    US Army Medical Research Institute of Infectious Diseases, Integrated Toxicology Division, 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA 1 301 619 4246 1 541 754 3545
    Expert Opin Drug Discov 6:233-50. 2011
  6. ncbi A STAT-1 knockout mouse model for Machupo virus pathogenesis
    Steven B Bradfute
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    Virol J 8:300. 2011

Collaborators

Detail Information

Publications6

  1. ncbi Standardization of the filovirus plaque assay for use in preclinical studies
    Amy C Shurtleff
    Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA
    Viruses 4:3511-30. 2012
    ..This protocol will be validated for use in GLP studies supporting advanced development of filovirus therapeutics and vaccines...
  2. ncbi The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment
    Amy C Shurtleff
    Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702, USA
    Viruses 4:3932-51. 2012
    ..The possibilities and limitations of biomedical research involving microbial pathogens of biodefense concern in BSL-4 containment laboratories are explored in this review...
  3. ncbi Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design
    Amy C Shurtleff
    U S Army Medical Research Institute of Infectious Diseases, Integrated Toxicology Division, Fort Detrick, 1425 Porter Street, Frederick, MD 21702, USA
    Expert Opin Drug Discov 7:935-54. 2012
    ..Additionally, targeting of protein-protein interactions may be a future avenue for drug discovery since disrupting catalytic sites may not be possible for all proteins...
  4. ncbi Advanced morpholino oligomers: a novel approach to antiviral therapy
    Travis K Warren
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21769, USA
    Antiviral Res 94:80-8. 2012
    ....
  5. ncbi Nonhuman primates as models for the discovery and development of ebolavirus therapeutics
    Amy C Shurtleff
    US Army Medical Research Institute of Infectious Diseases, Integrated Toxicology Division, 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA 1 301 619 4246 1 541 754 3545
    Expert Opin Drug Discov 6:233-50. 2011
    ..The advanced development and eventual licensure of therapeutic agents will require demonstration that mechanisms conferring protection in nonhuman primate models of infection are predictive of protective responses in humans...
  6. ncbi A STAT-1 knockout mouse model for Machupo virus pathogenesis
    Steven B Bradfute
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    Virol J 8:300. 2011
    ..This is due, in part, to a paucity of small animal models for MACV infection in which to discover and explore candidate therapeutics...