Phillip R Pittman

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. doi request reprint Immune interference after sequential alphavirus vaccine vaccinations
    Phillip R Pittman
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702 5011, United States
    Vaccine 27:4879-82. 2009
  2. ncbi request reprint Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Disease USAMRIID, Fort Detrick, MD 21702, United States
    Vaccine 24:3654-60. 2006
  3. pmc Protective antigen and toxin neutralization antibody patterns in anthrax vaccinees undergoing serial plasmapheresis
    Phillip R Pittman
    U S Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702 500, USA
    Clin Diagn Lab Immunol 12:713-21. 2005
  4. ncbi request reprint An assessment of health status among medical research volunteers who served in the Project Whitecoat program at Fort Detrick, Maryland
    Phillip R Pittman
    U S Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702 5011, USA
    Mil Med 170:183-7. 2005
  5. ncbi request reprint Long-term health effects of repeated exposure to multiple vaccines
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Maryland 21702 5011, USA
    Vaccine 23:525-36. 2004
  6. ncbi request reprint Antibody response to a delayed booster dose of anthrax vaccine and botulinum toxoid
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA
    Vaccine 20:2107-15. 2002
  7. ncbi request reprint Management guidelines for laboratory exposures to agents of bioterrorism
    Janice M Rusnak
    Special Immunizations Clinic, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA
    J Occup Environ Med 46:791-800. 2004
  8. doi request reprint An in vivo passive protection assay for the evaluation of immunity in AVA-vaccinated individuals
    John F Hewetson
    United States Army Medical Research Institute of Infections Diseases USAMRIID, Fort Detrick, MD 21702, United States
    Vaccine 26:4262-6. 2008
  9. ncbi request reprint Detection of antibodies to squalene: III. Naturally occurring antibodies to squalene in humans and mice
    Gary R Matyas
    Department of Membrane Biochemistry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    J Immunol Methods 286:47-67. 2004
  10. ncbi request reprint Analysis of adverse events after anthrax immunization in US Army medical personnel
    Glenn M Wasserman
    Preventive Medicine Department, Tripler Army Medical Center, Honolulu, Hawaii, USA
    J Occup Environ Med 45:222-33. 2003

Detail Information

Publications18

  1. doi request reprint Immune interference after sequential alphavirus vaccine vaccinations
    Phillip R Pittman
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702 5011, United States
    Vaccine 27:4879-82. 2009
    ..81; 95% CI=1.2-2.7 [p=0.0037]). Antibody interference and gender effect have major implications for vaccine strategy among those receiving multiple alphavirus vaccines and those developing next generation vaccines for these threats...
  2. ncbi request reprint Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Disease USAMRIID, Fort Detrick, MD 21702, United States
    Vaccine 24:3654-60. 2006
    ..The 6-month dose in the AVA primary series appears to be critical in sustaining IgG to PA concentrations in a substantial proportion of recipients...
  3. pmc Protective antigen and toxin neutralization antibody patterns in anthrax vaccinees undergoing serial plasmapheresis
    Phillip R Pittman
    U S Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702 500, USA
    Clin Diagn Lab Immunol 12:713-21. 2005
    ..Good correlation between IgG to PA and TNA antibodies suggests that the anti-PA enzyme-linked immunosorbent assay can be used as a high-throughput screen for functional immune reactivity in donor plasma units...
  4. ncbi request reprint An assessment of health status among medical research volunteers who served in the Project Whitecoat program at Fort Detrick, Maryland
    Phillip R Pittman
    U S Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702 5011, USA
    Mil Med 170:183-7. 2005
    ..6% vs. 18.3%, RR = 2.46, 95% CI = 0.99-6.15, p = 0.074). However, the size of the population under study was insufficient to assert with confidence that these statistical associations are real...
  5. ncbi request reprint Long-term health effects of repeated exposure to multiple vaccines
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Maryland 21702 5011, USA
    Vaccine 23:525-36. 2004
    ..5%) and control (4.5%) groups (RR = 2.7, P < 0.003) was observed; no associations with lifestyle, vaccine exposure, or medical conditions were found...
  6. ncbi request reprint Antibody response to a delayed booster dose of anthrax vaccine and botulinum toxoid
    Phillip R Pittman
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA
    Vaccine 20:2107-15. 2002
    ....
  7. ncbi request reprint Management guidelines for laboratory exposures to agents of bioterrorism
    Janice M Rusnak
    Special Immunizations Clinic, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA
    J Occup Environ Med 46:791-800. 2004
    ..Algorithms for evaluating and managing potential exposures are presented to provide guidance to other agencies as they begin to work with these agents...
  8. doi request reprint An in vivo passive protection assay for the evaluation of immunity in AVA-vaccinated individuals
    John F Hewetson
    United States Army Medical Research Institute of Infections Diseases USAMRIID, Fort Detrick, MD 21702, United States
    Vaccine 26:4262-6. 2008
    ..This analytical method may provide additional opportunities to compare the efficacy of improved anthrax vaccines with the licensed vaccine...
  9. ncbi request reprint Detection of antibodies to squalene: III. Naturally occurring antibodies to squalene in humans and mice
    Gary R Matyas
    Department of Membrane Biochemistry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    J Immunol Methods 286:47-67. 2004
    ..7%) and males (12.5%). We conclude that antibodies to SQE occur naturally in humans; have an increased prevalence in females; are not correlated with vaccination with AVA; and appear to increase in prevalence with age...
  10. ncbi request reprint Analysis of adverse events after anthrax immunization in US Army medical personnel
    Glenn M Wasserman
    Preventive Medicine Department, Tripler Army Medical Center, Honolulu, Hawaii, USA
    J Occup Environ Med 45:222-33. 2003
    ..Our findings suggest that AVA is relatively reactogenic but do not indicate serious adverse health effects due to immunization...
  11. ncbi request reprint Aluminum-containing vaccine associated adverse events: role of route of administration and gender
    Phillip R Pittman
    Vaccine 20:S48-50. 2002
    ..q. nodules were more common in women compared with men (P < 0.001) after the first s.q. dose of AVA dose. Reaction rates decreased when the interval between the first two doses of AVA was increased from 2 to 4 weeks...
  12. doi request reprint Th17 cytokines in recall responses against Francisella tularensis in humans
    Chrysanthi Paranavitana
    Department of Dangerous Bacterial Pathogens, Walter Reed Army Institute of Research, Silver Spring, Maryland 20190, USA
    J Interferon Cytokine Res 30:471-6. 2010
    ..These findings suggest that Th17 responses in addition to the Th1 response may play an important role in adaptive immunity against Francisella...
  13. ncbi request reprint Immunization to protect the US Armed Forces: heritage, current practice, and prospects
    John D Grabenstein
    Military Vaccine Agency, Office of the Surgeon General, US Army, Falls Church, VA 22041, USA
    Epidemiol Rev 28:3-26. 2006
    ..Military immunization programs maintain the health of soldiers, marines, sailors, airmen, and coast guardsmen, the resources most critical to military success...
  14. doi request reprint Transcriptional profiling of Francisella tularensis infected peripheral blood mononuclear cells: a predictive tool for tularemia
    Chrysanthi Paranavitana
    Department of Bacterial and Rickettsial Diseases, Walter Reed Army Institute of Research, Silver Spring, MD 20190, USA
    FEMS Immunol Med Microbiol 54:92-103. 2008
    ..Ultimately, this study provides support for utilizing in vitro microarray gene expression profiling in human PBMCs to identify biomarkers of infection and predict in vivo immune responses to infectious agents...
  15. ncbi request reprint Anthrax vaccine: immunogenicity and safety of a dose-reduction, route-change comparison study in humans
    Phillip R Pittman
    Division of Medicine, United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, MD 21702 5011, USA
    Vaccine 20:1412-20. 2002
    ..A large pivotal study is being planned by the Centers for Disease Control and Prevention to confirm these results...
  16. pmc Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccination
    Claudette L Fuller
    United States Army Medical Research Institute of Infectious Diseases, Bacteriology Division, 1425 Porter Street, Frederick, MD 21702 5011, USA
    Mol Immunol 44:3173-84. 2007
    ..tularensis. Additionally, we obtained valuable information that should prove useful in evaluation of vaccine lots as well as efficacy testing of new anti-F. tularensis vaccines...
  17. ncbi request reprint Dominance of human innate immune responses in primary Francisella tularensis live vaccine strain vaccination
    Claudette L Fuller
    J Allergy Clin Immunol 117:1186-8. 2006