Research Topics
| P R PittmanSummaryAffiliation: Walter Reed Army Medical Center Country: USA Publications
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Detail Information
Publications
Anthrax vaccine: short-term safety experience in humansP R Pittman
Division of Medicine, US Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Frederick, MD 21702 5011, USA
Vaccine 20:972-8. 2001....- Anthrax vaccine: immunogenicity and safety of a dose-reduction, route-change comparison study in humansPhillip R Pittman
Division of Medicine, United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, MD 21702 5011, USA
Vaccine 20:1412-20. 2002..A large pivotal study is being planned by the Centers for Disease Control and Prevention to confirm these results... - Aluminum-containing vaccine associated adverse events: role of route of administration and genderPhillip R Pittman
Vaccine 20:S48-50. 2002..q. nodules were more common in women compared with men (P < 0.001) after the first s.q. dose of AVA dose. Reaction rates decreased when the interval between the first two doses of AVA was increased from 2 to 4 weeks... - Neutralizing antibody response to booster vaccination with the 17d yellow fever vaccineM J Hepburn
Division of Medicine, United States Army Medical Research Institute for Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702 5011, USA
Vaccine 24:2843-9. 2006..The median times to titer failure (<1:40) were 798 days (Group 1), 3340 days (Group 2) and 7709 days (Group 3) (p<0.0001). Pre-vaccination serology influenced the initial and long-term response to yellow fever booster vaccination... 
An in vivo passive protection assay for the evaluation of immunity in AVA-vaccinated individualsJohn F Hewetson
United States Army Medical Research Institute of Infections Diseases USAMRIID, Fort Detrick, MD 21702, United States
Vaccine 26:4262-6. 2008..This analytical method may provide additional opportunities to compare the efficacy of improved anthrax vaccines with the licensed vaccine...
Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccinationClaudette L Fuller
United States Army Medical Research Institute of Infectious Diseases, Bacteriology Division, 1425 Porter Street, Frederick, MD 21702 5011, USA
Mol Immunol 44:3173-84. 2007..tularensis. Additionally, we obtained valuable information that should prove useful in evaluation of vaccine lots as well as efficacy testing of new anti-F. tularensis vaccines...- Immunization to protect the US Armed Forces: heritage, current practice, and prospectsJohn D Grabenstein
Military Vaccine Agency, Office of the Surgeon General, US Army, Falls Church, VA 22041, USA
Epidemiol Rev 28:3-26. 2006..Military immunization programs maintain the health of soldiers, marines, sailors, airmen, and coast guardsmen, the resources most critical to military success... - Dominance of human innate immune responses in primary Francisella tularensis live vaccine strain vaccinationClaudette L Fuller
J Allergy Clin Immunol 117:1186-8. 2006 - Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) seriesPhillip R Pittman
United States Army Medical Research Institute of Infectious Disease USAMRIID, Fort Detrick, MD 21702, United States
Vaccine 24:3654-60. 2006..The 6-month dose in the AVA primary series appears to be critical in sustaining IgG to PA concentrations in a substantial proportion of recipients... - Protective antigen and toxin neutralization antibody patterns in anthrax vaccinees undergoing serial plasmapheresisPhillip R Pittman
U S Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702 500, USA
Clin Diagn Lab Immunol 12:713-21. 2005..Good correlation between IgG to PA and TNA antibodies suggests that the anti-PA enzyme-linked immunosorbent assay can be used as a high-throughput screen for functional immune reactivity in donor plasma units... - An assessment of health status among medical research volunteers who served in the Project Whitecoat program at Fort Detrick, MarylandPhillip R Pittman
U S Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702 5011, USA
Mil Med 170:183-7. 2005..6% vs. 18.3%, RR = 2.46, 95% CI = 0.99-6.15, p = 0.074). However, the size of the population under study was insufficient to assert with confidence that these statistical associations are real... - Long-term health effects of repeated exposure to multiple vaccinesPhillip R Pittman
United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Maryland 21702 5011, USA
Vaccine 23:525-36. 2004..5%) and control (4.5%) groups (RR = 2.7, P < 0.003) was observed; no associations with lifestyle, vaccine exposure, or medical conditions were found... - Management guidelines for laboratory exposures to agents of bioterrorismJanice M Rusnak
Special Immunizations Clinic, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA
J Occup Environ Med 46:791-800. 2004..Algorithms for evaluating and managing potential exposures are presented to provide guidance to other agencies as they begin to work with these agents... - Detection of antibodies to squalene: III. Naturally occurring antibodies to squalene in humans and miceGary R Matyas
Department of Membrane Biochemistry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
J Immunol Methods 286:47-67. 2004..7%) and males (12.5%). We conclude that antibodies to SQE occur naturally in humans; have an increased prevalence in females; are not correlated with vaccination with AVA; and appear to increase in prevalence with age... - Analysis of adverse events after anthrax immunization in US Army medical personnelGlenn M Wasserman
Preventive Medicine Department, Tripler Army Medical Center, Honolulu, Hawaii, USA
J Occup Environ Med 45:222-33. 2003..Our findings suggest that AVA is relatively reactogenic but do not indicate serious adverse health effects due to immunization... - Antibody response to a delayed booster dose of anthrax vaccine and botulinum toxoidPhillip R Pittman
United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA
Vaccine 20:2107-15. 2002.... - Transcriptional profiling of Francisella tularensis infected peripheral blood mononuclear cells: a predictive tool for tularemiaChrysanthi Paranavitana
Department of Bacterial and Rickettsial Diseases, Walter Reed Army Institute of Research, Silver Spring, MD 20190, USA
FEMS Immunol Med Microbiol 54:92-103. 2008..Ultimately, this study provides support for utilizing in vitro microarray gene expression profiling in human PBMCs to identify biomarkers of infection and predict in vivo immune responses to infectious agents...