Jason F Okulicz

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. doi request reprint CD4 T cell count reconstitution in HIV controllers after highly active antiretroviral therapy
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda, Maryland, USA
    Clin Infect Dis 50:1187-91. 2010
  2. pmc Clinical, demographic and laboratory parameters at HAART initiation associated with decreased post-HAART survival in a U.S. military prospective HIV cohort
    Alan R Lifson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    AIDS Res Ther 9:4. 2012
  3. pmc The impact of enzyme-inducing antiepileptic drugs on antiretroviral drug levels: a case-control study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Epilepsy Res 103:245-53. 2013
  4. pmc Spontaneous virologic suppression in HIV controllers is independent of delayed-type hypersensitivity test responsiveness
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    AIDS Res Ther 9:10. 2012
  5. pmc Virologic outcomes of HAART with concurrent use of cytochrome P450 enzyme-inducing antiepileptics: a retrospective case control study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    AIDS Res Ther 8:18. 2011
  6. doi request reprint Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    J Infect Dis 200:1714-23. 2009
  7. pmc Hepatitis B vaccine antibody response and the risk of clinical AIDS or death
    Michael L Landrum
    Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland, United States of America
    PLoS ONE 7:e33488. 2012
  8. doi request reprint Characterizing the Association Between Alcohol and HIV Virologic Failure in a Military Cohort on Antiretroviral Therapy
    Robert G Deiss
    Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland
    Alcohol Clin Exp Res 40:529-35. 2016
  9. pmc Early postseroconversion CD4 cell counts independently predict CD4 cell count recovery in HIV-1-postive subjects receiving antiretroviral therapy
    Hemant Kulkarni
    Veterans Administration Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, San Antonio, TX, USA
    J Acquir Immune Defic Syndr 57:387-95. 2011
  10. pmc Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy
    Tuan Le
    Veterans Affairs Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, San Antonio, Texas, USA
    N Engl J Med 368:218-30. 2013

Collaborators

Detail Information

Publications28

  1. doi request reprint CD4 T cell count reconstitution in HIV controllers after highly active antiretroviral therapy
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda, Maryland, USA
    Clin Infect Dis 50:1187-91. 2010
    ..HIV controllers experienced CD4 cell count reconstitution with HAART regardless of pretherapy viral load, including patients with undetectable viral loads at HAART initiation...
  2. pmc Clinical, demographic and laboratory parameters at HAART initiation associated with decreased post-HAART survival in a U.S. military prospective HIV cohort
    Alan R Lifson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    AIDS Res Ther 9:4. 2012
    ..Although highly active antiretroviral therapy (HAART) has improved HIV survival, some patients receiving therapy are still dying. This analysis was conducted to identify factors associated with increased risk of post-HAART mortality...
  3. pmc The impact of enzyme-inducing antiepileptic drugs on antiretroviral drug levels: a case-control study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Epilepsy Res 103:245-53. 2013
    ..To evaluate the impact of enzyme-inducing antiepileptic drugs (EI-AEDs) on serum antiretroviral (ARV) levels in patients with HIV...
  4. pmc Spontaneous virologic suppression in HIV controllers is independent of delayed-type hypersensitivity test responsiveness
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    AIDS Res Ther 9:10. 2012
    ..abstract:..
  5. pmc Virologic outcomes of HAART with concurrent use of cytochrome P450 enzyme-inducing antiepileptics: a retrospective case control study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    AIDS Res Ther 8:18. 2011
    ..abstract:..
  6. doi request reprint Clinical outcomes of elite controllers, viremic controllers, and long-term nonprogressors in the US Department of Defense HIV natural history study
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    J Infect Dis 200:1714-23. 2009
    ..042). Definitions of controllers and LTNPs describe distinct populations whose differing clinical outcomes improve with the stringency of criteria, underscoring the need for comparability between study populations...
  7. pmc Hepatitis B vaccine antibody response and the risk of clinical AIDS or death
    Michael L Landrum
    Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland, United States of America
    PLoS ONE 7:e33488. 2012
    ..This study evaluated the relationship between HBV vaccine seroresponses and progression to clinical AIDS or death...
  8. doi request reprint Characterizing the Association Between Alcohol and HIV Virologic Failure in a Military Cohort on Antiretroviral Therapy
    Robert G Deiss
    Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland
    Alcohol Clin Exp Res 40:529-35. 2016
    ..We investigated the impact of self-reported alcohol consumption on surrogate markers of HIV progression among individuals initiated on highly active antiretroviral therapy (HAART)...
  9. pmc Early postseroconversion CD4 cell counts independently predict CD4 cell count recovery in HIV-1-postive subjects receiving antiretroviral therapy
    Hemant Kulkarni
    Veterans Administration Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, San Antonio, TX, USA
    J Acquir Immune Defic Syndr 57:387-95. 2011
    ..The relationship between CD4 T-cell counts determined soon after seroconversion with HIV-1 (baseline CD4), nadir CD4, and CD4 levels attained during highly active antiretroviral therapy (HAART) is unknown...
  10. pmc Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy
    Tuan Le
    Veterans Affairs Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, San Antonio, Texas, USA
    N Engl J Med 368:218-30. 2013
    ..The relationship between the timing of the initiation of antiretroviral therapy (ART) after infection with human immunodeficiency virus type 1 (HIV-1) and the recovery of CD4+ T-cell counts is unknown...
  11. doi request reprint Development of chronic hepatitis B virus infection in hepatitis B surface antigen negative HIV/HBV co-infected adults: a rare opportunistic illness
    Michael L Landrum
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, Texas
    J Med Virol 83:1537-43. 2011
    ..The occurrence of late-onset chronic HBV infection in HBsAg negative HIV/HBV co-infected adults appears to be one important, albeit rare, clinical event seen almost exclusively in those with isolated anti-HBc and low CD4 cell count...
  12. pmc Elevated CD8 counts during HAART are associated with HIV virologic treatment failure
    Elizabeth M Krantz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 57:396-403. 2011
    ..To evaluate whether elevated CD8 counts are associated with increased risk of virologic treatment failure in HIV-infected individuals...
  13. doi request reprint A single dose of benzathine penicillin G is as effective as multiple doses of benzathine penicillin G for the treatment of HIV-infected persons with early syphilis
    Anuradha Ganesan
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland Walter Reed National Military Medical Center, Washington, District of Columbia
    Clin Infect Dis 60:653-60. 2015
    ..However, data supporting this recommendation are limited. We examined the efficacy of single-dose BPG in the US Military HIV Natural History Study...
  14. pmc The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry
    Hemant Kulkarni
    Veterans Administration Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, San Antonio, USA
    Blood 114:2783-92. 2009
    ....
  15. pmc Is Kaposi's sarcoma occurring at higher CD4 cell counts over the course of the HIV epidemic?
    Nancy F Crum-Cianflone
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    AIDS 24:2881-3. 2010
    ..These data support future studies evaluating the impact of highly active antiretroviral therapy initiation at higher CD4 cell counts to further reduce Kaposi's sarcoma...
  16. pmc Association between hepatitis B vaccine antibody response and CD4 reconstitution after initiation of combination antiretroviral therapy in HIV-infected persons
    Kahtonna Allen
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    BMC Infect Dis 15:203. 2015
    ..We evaluated the relationship between HBV vaccine response status and CD4 reconstitution on cART in the U.S Military HIV Natural History Study...
  17. pmc Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of Health Sciences, Bethesda, Maryland2Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, Texas
    JAMA Intern Med 175:88-99. 2015
    ..In individuals with human immunodeficiency virus 1 (HIV-1) infection who are receiving antiretroviral therapy (ART), factors that promote full immune recovery are not well characterized...
  18. pmc The VACS index predicts mortality in a young, healthy HIV population starting highly active antiretroviral therapy
    Ionut Bebu
    Department of Preventive Medicine and Biometrics, Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, MD Yale University School of Medicine and the Veterans Affairs Healthcare Systems, West Haven, CT Veterans Affairs Medical Center and Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA Division of Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, MD Division of Infectious Diseases, San Antonio Military Medical Center, TX and Division of Infectious Diseases, Naval Medical Center San Diego, CA
    J Acquir Immune Defic Syndr 65:226-30. 2014
    ..A significant portion of the US HIV population is similarly composed; so, evaluation of the VACS index in this population is of great interest...
  19. pmc Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: the U.S. Military HIV Natural History Study
    Vincent C Marconi
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    AIDS Res Ther 7:14. 2010
    ..abstract:..
  20. doi request reprint Toxoplasma gondii seroprevalence: 30-year trend in an HIV-infected US military cohort
    Thomas A O'Bryan
    Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA Electronic address
    Diagn Microbiol Infect Dis 84:34-5. 2016
    ..We found that T. gondii seroprevalence at enrollment was associated with age and decreased significantly after 1995 (P=0.004), similar to the general US population. ..
  21. pmc Hospitalizations among HIV controllers and persons with medically controlled HIV in the U.S. Military HIV Natural History Study
    Trevor A Crowell
    U S Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    J Int AIDS Soc 19:20524. 2016
    ..The objective of this study was to characterize the rates and reasons for hospitalization among HICs and persons with medically controlled HIV...
  22. pmc Impact of the highly active antiretroviral therapy era on the epidemiology of primary HIV-associated thrombocytopenia
    Thomas A O'Bryan
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    BMC Res Notes 8:595. 2015
    ..Data comparing the epidemiology of PHAT between the pre-HAART and HAART eras are limited. We retrospectively examined the incidence of PHAT over 28 years in the US Military HIV Natural History Study (NHS) from 1986 to 2013...
  23. pmc Hepatitis B vaccine responsiveness and clinical outcomes in HIV controllers
    Jason F Okulicz
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America Infectious Disease Service, San Antonio Military Medical Center, San Antonio, Texas, United States of America
    PLoS ONE 9:e105591. 2014
    ..Although HIV controllers (HIC) typically have favorable immunologic and clinical characteristics compared to non-controllers, vaccine responsiveness has not been studied...
  24. ncbi request reprint Evaluation of HIV postexposure prophylaxis for occupational and nonoccupational exposures at a deployed U.S. military trauma hospital
    Jason F Okulicz
    San Antonio Military Medical Center, Infectious Disease Service, 3551 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
    Mil Med 177:1524-32. 2012
    ..Since exposures to blood and other body fluids commonly occur in a combat setting, it is important to evaluate PEP utilization in the deployed environment...
  25. doi request reprint Occupational exposures and the prevalence of blood-borne pathogens in a deployed setting: data from a US military trauma center in Afghanistan
    Jason F Okulicz
    Infectious Disease Service, San Antonio Military Medical Center, San Antonio, Texas, USA
    Infect Control Hosp Epidemiol 34:74-9. 2013
    ....
  26. pmc Mendelian randomization: potential use of genetics to enable causal inferences regarding HIV-associated biomarkers and outcomes
    Weijing He
    Veterans Administration Research Center for AIDS and HIV 1 Infection, South Texas Veterans Healthcare System, Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Curr Opin HIV AIDS 5:545-59. 2010
    ..Here, we discuss the potential use of Mendelian randomization for differentiating whether biomarkers are correlating with or causal for HIV-associated outcomes...
  27. pmc Delayed-type hypersensitivity (DTH) test anergy does not impact CD4 reconstitution or normalization of DTH responses during antiretroviral therapy
    Natascha M Minidis
    Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA Infectious Disease Service, San Antonio Military Medical Center San Antonio, TX, USA
    J Int AIDS Soc 17:18799. 2014
    ..We investigated CD4 reconstitution and the change in DTH responses from treatment baseline through 24 months of viral load (VL)-suppressive HAART in the U.S. Military HIV Natural History Study...
  28. doi request reprint Epidemiology and clinical characteristics of elite controllers
    Jason F Okulicz
    Infectious Disease Service, San Antonio Military Medical Center, San Antonio, Texas, USA
    Curr Opin HIV AIDS 6:163-8. 2011
    ..Recent studies have been published characterizing the epidemiology of elite controllers. The demographic features, clinical characteristics, and HIV disease outcomes of elite controllers are summarized...