B C Nindl

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint Gender differences in regional body composition and somatotrophic influences of IGF-I and leptin
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 92:1611-8. 2002
  2. doi request reprint Insulin-like growth factor-I, physical activity, and control of cellular anabolism
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 42:35-8. 2010
  3. ncbi request reprint Physiological consequences of U.S. Army Ranger training
    Bradley C Nindl
    Military Performance, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 39:1380-7. 2007
  4. ncbi request reprint Physical performance responses during 72 h of military operational stress
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 34:1814-22. 2002
  5. ncbi request reprint Differential responses of IGF-I molecular complexes to military operational field training
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 95:1083-9. 2003
  6. ncbi request reprint Utility of circulating IGF-I as a biomarker for assessing body composition changes in men during periods of high physical activity superimposed upon energy and sleep restriction
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    J Appl Physiol 103:340-6. 2007
  7. pmc Exercise modulation of growth hormone isoforms: current knowledge and future directions for the exercise endocrinologist
    B C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA, USA
    Br J Sports Med 41:346-8; discussion 348. 2007
  8. ncbi request reprint Measurement of insulin-like growth factor-I during military operational stress via a filter paper blood spot assay
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    Diabetes Technol Ther 5:455-61. 2003
  9. ncbi request reprint Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    Diabetes Technol Ther 8:244-52. 2006
  10. ncbi request reprint Growth hormone molecular heterogeneity and exercise
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Exerc Sport Sci Rev 31:161-6. 2003

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Gender differences in regional body composition and somatotrophic influences of IGF-I and leptin
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 92:1611-8. 2002
    ....
  2. doi request reprint Insulin-like growth factor-I, physical activity, and control of cellular anabolism
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 42:35-8. 2010
    ..The IGF-I system remains one of the most intriguing and captivating marvels of human physiology that seems central in mediating numerous adaptations from physical activity...
  3. ncbi request reprint Physiological consequences of U.S. Army Ranger training
    Bradley C Nindl
    Military Performance, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 39:1380-7. 2007
    ..This study examined the physiological consequences of U.S. Army Ranger training on strength, power, body composition, and somatotrophic hormones...
  4. ncbi request reprint Physical performance responses during 72 h of military operational stress
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 34:1814-22. 2002
    ..To characterize the impact of prolonged work, underfeeding, and sleep deprivation (i.e., sustained operations; SUSOPS) on physical and occupational related performance during military operational stress...
  5. ncbi request reprint Differential responses of IGF-I molecular complexes to military operational field training
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 95:1083-9. 2003
    ..the relative proportion of IGF-I sequestered in ternary vs. nonternary molecular complexes appears to be well maintained...
  6. ncbi request reprint Utility of circulating IGF-I as a biomarker for assessing body composition changes in men during periods of high physical activity superimposed upon energy and sleep restriction
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    J Appl Physiol 103:340-6. 2007
    ....
  7. pmc Exercise modulation of growth hormone isoforms: current knowledge and future directions for the exercise endocrinologist
    B C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA, USA
    Br J Sports Med 41:346-8; discussion 348. 2007
  8. ncbi request reprint Measurement of insulin-like growth factor-I during military operational stress via a filter paper blood spot assay
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    Diabetes Technol Ther 5:455-61. 2003
    ..The filter paper blood spot method for IGF-I detected reductions accompanying nutritional stress and may be of potential value for characterizing the IGF-I response when conventional blood sampling methods are not feasible...
  9. ncbi request reprint Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    Diabetes Technol Ther 8:244-52. 2006
    ..Additionally, the IGF-I measurements in these two biocompartments were not closely associated, possibly indicating an uncoupled, rather than a linked, regulation of IGF-I among the body's biocompartments...
  10. ncbi request reprint Growth hormone molecular heterogeneity and exercise
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Exerc Sport Sci Rev 31:161-6. 2003
    ..e., 22 kDa). New assay methodologies now can assess various GH isoforms. The current data suggest that exercise results in the preferential release of GH isoforms with extended half-lives, thereby sustaining biological actions...
  11. ncbi request reprint Leptin concentrations experience a delayed reduction after resistance exercise in men
    Bradley C Nindl
    Intercollege Graduate Program in Physiology, Department of Kinesiology, The Pennsylvania State University, University Park, PA, USA
    Med Sci Sports Exerc 34:608-13. 2002
    ..We hypothesized that these studies have been limited by short sampling schemes (<4 h) postexercise and may have missed a time-delayed reduction in circulating leptin concentrations...
  12. ncbi request reprint Overnight responses of the circulating IGF-I system after acute, heavy-resistance exercise
    B C Nindl
    Intercollege Graduate Program in Physiology, The Pennsylvania State University, University Park, Pennsylvania 16801, USA
    J Appl Physiol 90:1319-26. 2001
    ..Thus acute, heavy-resistance exercise can lead to alterations in the IGF-I system that can be detected in the systemic circulation...
  13. doi request reprint Relationship between growth hormone in vivo bioactivity, the insulin-like growth factor-I system and bone mineral density in young, physically fit men and women
    B C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Growth Horm IGF Res 18:439-45. 2008
    ..The in vivo bioassay for GH (bioGH) provides a more physiologically relevant measurement than an in vitro immunoassay, since bioGH is quantified on a biological outcome...
  14. ncbi request reprint Growth hormone pulsatility profile characteristics following acute heavy resistance exercise
    B C Nindl
    Intercollege Graduate Program in Physiology, The Pennsylvania State University, University Park, Pennsylvania 16801, USA
    J Appl Physiol 91:163-72. 2001
    ..Additionally, because of the unique molecular basis of the DSL IFA, this influence does have biological relevance because functionally intact molecules are affected...
  15. ncbi request reprint LH secretion and testosterone concentrations are blunted after resistance exercise in men
    B C Nindl
    Intercollege Graduate Program in Physiology, The Pennsylvania State University, University Park, Pennsylvania 16801, USA
    J Appl Physiol 91:1251-8. 2001
    ..These data demonstrate that the decline in overnight testosterone concentrations after acute heavy-resistance exercise is accompanied by a blunted LH production rate and elevated C concentrations...
  16. ncbi request reprint Immunofunctional vs immunoreactive growth hormone responses after resistance exercise in men and women
    B C Nindl
    Intercollege Graduate Program in Physiology, The Pennsylvania State University, University Park, PA 16801, USA
    Growth Horm IGF Res 10:99-103. 2000
    ..In summary, dynamic exercise elicited a similar rise in M and W for immunofunctionally active GH molecules, but the magnitude is lower than when detected with another conventional assay...
  17. ncbi request reprint Regional body composition changes in women after 6 months of periodized physical training
    B C Nindl
    Department of Kinesiology, The Pennsylvania State University, University Park 16802, USA
    J Appl Physiol 88:2251-9. 2000
    ..5% increases in leg lean tissue. These findings show the importance of considering regional body composition changes, rather than whole body changes alone when assessing the effects of a periodized physical training program...
  18. ncbi request reprint Lymphocyte proliferation in response to acute heavy resistance exercise in women: influence of muscle strength and total work
    K Dohi
    Laboratory for Sports Medicine, Department of Kinesiology, Center for Sports Medicine, Pennsylvania State University, University Park, PA 16802, USA
    Eur J Appl Physiol 85:367-73. 2001
    ..Therefore, individuals performing at the same relative exercise intensity (i.e. 10 RM) in a resistance exercise protocol may have different immune responses stemming from differences in absolute total work performance...
  19. ncbi request reprint Effect of resistance training on women's strength/power and occupational performances
    W J Kraemer
    Laboratory for Sports Medicine Center for Sports Medicine, The Pennsylvania State University, University Park, PA 16802, USA
    Med Sci Sports Exerc 33:1011-25. 2001
    ..The effects of resistance training programs on strength, power, and military occupational task performances in women were examined...
  20. ncbi request reprint Characteristics of circulating growth hormone in women after acute heavy resistance exercise
    W C Hymer
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Am J Physiol Endocrinol Metab 281:E878-87. 2001
    ..Finally, because most of the GH released after exercise was able to dimerize the GH receptor in vitro, it is also concluded that these forms have the two intact binding sites required to initiate signal transduction in target cells...
  21. ncbi request reprint Influence of muscle strength and total work on exercise-induced plasma growth hormone isoforms in women
    W J Kraemer
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, Conneticut, USA
    J Sci Med Sport 6:295-306. 2003
    ....
  22. ncbi request reprint Energy flux, more so than energy balance, protein intake, or fitness level, influences insulin-like growth factor-I system responses during 7 days of increased physical activity
    Kevin R Rarick
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 103:1613-21. 2007
    ....
  23. ncbi request reprint Testosterone responses after resistance exercise in women: influence of regional fat distribution
    B C Nindl
    Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Int J Sport Nutr Exerc Metab 11:451-65. 2001
    ..In young, healthy women, resistance exercise can induce transient increases in testosterone, and anthropometric markers of adiposity correlate with testosterone concentrations...
  24. ncbi request reprint Physical performance and metabolic recovery among lean, healthy men following a prolonged energy deficit
    B C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Int J Sports Med 18:317-24. 1997
    ....
  25. ncbi request reprint Effects of intensified military field training on jumping performance
    T T Welsh
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Int J Sports Med 29:45-52. 2008
    ....
  26. doi request reprint Effects of dietary protein content on IGF-I, testosterone, and body composition during 8 days of severe energy deficit and arduous physical activity
    Joseph A Alemany
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 105:58-64. 2008
    ..01). Dietary protein content of 0.5 and 0.9 g/kg minimally attenuated the decline of IGF-I, the androgenic system, and fat-free mass during 8 days of negative energy balance associated with high energy expenditure and low energy intake...
  27. ncbi request reprint Peripheral QCT sector analysis reveals early exercise-induced increases in tibial bone mineral density
    R K Evans
    US Army Research Institute of Environmental Medicine, Natick, MA, USA
    J Musculoskelet Neuronal Interact 12:155-64. 2012
    ..The purpose of this controlled trial was to determine whether subtle changes in mineralization and geometry of the tibia were evident following short term exercise interventions...
  28. ncbi request reprint Reliability assessment of two militarily relevant occupational physical performance tests
    Clay E Pandorf
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA, USA
    Can J Appl Physiol 28:27-37. 2003
    ..This study demonstrates that both are reliable tests, but they do require administration of 1 single-trial session of RBLT and 2 two-trial sessions of OC before highly reliable performance data are obtained...
  29. ncbi request reprint Effects of aging on human skeletal muscle myosin heavy-chain mRNA content and protein isoform expression
    James O Marx
    Noll Physiological Research Center, The Pennsylvania State University, University Park 16802, USA
    J Gerontol A Biol Sci Med Sci 57:B232-8. 2002
    ..Thus, the present results do not support the hypothesis that pretranslational events in MyHC protein synthesis are playing a significant role in the development of sarcopenia...
  30. ncbi request reprint Effects of concurrent resistance and aerobic training on load-bearing performance and the Army physical fitness test
    William J Kraemer
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT 06269, USA
    Mil Med 169:994-9. 2004
    ..Army Physical Fitness Test performance, loaded running, and leg power responded positively to training, however, it appears there is a high degree of specificity when concurrent training regimens are implemented...
  31. doi request reprint A novel, noninvasive transdermal fluid sampling methodology: IGF-I measurement following exercise
    D E Scofield
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Am J Physiol Regul Integr Comp Physiol 300:R1326-32. 2011
    ..Moreover, our finding that the proportion of free to tIGF-I was greater in TDF than in serum suggests that changes in local IGF-I may be captured more readily using this system...
  32. ncbi request reprint Prediction of simulated battlefield physical performance from field-expedient tests
    Everett A Harman
    US Army Research Institute of Environmental Medicine, Kansas Street, Natick, MA 01760 5007, USA
    Mil Med 173:36-41. 2008
    ..77-0.82). The vertical jump entered all four prediction equations and the horizontal jump entered one of them. The equations, using input from easy to administer tests, effectively predict simulated battlefield physical performance...
  33. ncbi request reprint Effects of resistance training on neuromuscular junction morphology
    M R Deschenes
    Department of Kinesiology, College of William and Mary, Williamsburg, Virginia 23187 8795, USA
    Muscle Nerve 23:1576-81. 2000
    ..The data presented here indicate that the stimulus of resistance training was sufficiently potent to remodel NMJ structure, and that this effect cannot be attributed to muscle fiber hypertrophy or fiber type conversion...
  34. ncbi request reprint Strength, workload, anaerobic intensity and the immune response to resistance exercise in women
    M P Miles
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, PA, USA
    Acta Physiol Scand 178:155-63. 2003
    ..The purpose of this investigation was to determine whether the immune response to resistance exercise was associated with (1) changes in workload or (2) anaerobic exercise intensity...
  35. doi request reprint Effects of exercise training on the matrix metalloprotease response to acute exercise
    Maria L Urso
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Building 42, Natick, MA 01760, USA
    Eur J Appl Physiol 106:655-63. 2009
    ..RT did not alter MMP-3 and -9 concentrations. These data suggest that the mode of exercise training influences the MMP response to an acute bout of exercise, revealing a possible role of MMPs in initiating training-specific adaptations...
  36. doi request reprint Effects of acute and chronic exercise on disulfide-linked growth hormone variants
    Joseph R Pierce
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA, USA
    Med Sci Sports Exerc 41:581-7. 2009
    ..To test the hypothesis that the appearance of disulfide-linked growth hormone (GH) aggregates during and after an acute resistance exercise test (ARET) in men could be influenced by chronic physical training...
  37. doi request reprint Effects of exercise mode and duration on 24-h IGF-I system recovery responses
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 41:1261-70. 2009
    ..This study hypothesized that insulin-like growth factor-binding protein (IGFBP), rather than insulin-like growth factor I (IGF-I) itself, would be more responsive to acute exercise stress in a dose-dependent fashion...
  38. doi request reprint Loss of IGF-IEa or IGF-IEb impairs myogenic differentiation
    Ronald W Matheny
    United States Army Research Institute of Environmental Medicine, Military Performance Division, Natick, Massachusetts 01760, USA
    Endocrinology 152:1923-34. 2011
    ..Collectively, these data suggest that IGF-I splice variants may regulate myoblast differentiation through the actions of mature IGF-I and not the E peptides...
  39. doi request reprint Combined resistance and endurance training improves physical capacity and performance on tactical occupational tasks
    Nathan R Hendrickson
    Military Performance Division, US Army Research Institute of Environmental Medicine, Building 42, Kansas Street, Natick, MA 01760, USA
    Eur J Appl Physiol 109:1197-208. 2010
    ..In conclusion, 8 weeks of combined training improved performance in all tactical occupational tasks measured and did not interfere with improvements in strength, power and endurance measures compared to R or E alone...
  40. doi request reprint Hypohydration reduces vertical ground reaction impulse but not jump height
    Samuel N Cheuvront
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas Street, Natick, MA 01760 5007, USA
    Eur J Appl Physiol 109:1163-70. 2010
    ..05). In conclusion, this study demonstrates the failure to improve jump height when HYP can be explained by offsetting reductions in both VGRI and body mass...
  41. doi request reprint Diet, body composition, and physical fitness influences on IGF-I bioactivity in women
    J Philip Karl
    US Army Research Institute of Environmental Medicine, 42 Kansas St, Natick, MA 01760, USA
    Growth Horm IGF Res 19:491-6. 2009
    ..The influence of these factors on IGF-I bioactivity; however, is undetermined. We assessed the relationships between IGF-I bioactivity and lifestyle factors purportedly associated with IGF-I immunoreactivity...
  42. doi request reprint Randomized, double-blind, placebo-controlled trial of iron supplementation in female soldiers during military training: effects on iron status, physical performance, and mood
    James P McClung
    Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Am J Clin Nutr 90:124-31. 2009
    ..Decrements in iron status have been reported in female soldiers during military training. Diminished iron status adversely affects physical and cognitive performance...
  43. doi request reprint Insulin-like growth factor I as a biomarker of health, fitness, and training status
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 42:39-49. 2010
    ..We believe that such endeavors will provide greater understanding in the complex role that IGF-I possesses in mediating exercise-induced adaptations...
  44. pmc Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration
    Ronald W Matheny
    U S Army Research Institute of Environmental Medicine, Military Performance Division, 15 Kansas Street, Building 42, Natick, Massachusetts 01760, USA
    Endocrinology 151:865-75. 2010
    ..Additionally, the role of MGF in satellite cell activation, aging, neuroprotection, and signaling will be discussed. A survey of outstanding questions relating to MGF will also be provided...
  45. pmc Insulin-like growth factor-I as a candidate metabolic biomarker: military relevance and future directions for measurement
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    J Diabetes Sci Technol 3:371-6. 2009
    ..Minimally invasive technologies that are field expedient, cost-effective, and allow for continuous and real-time feedback will have the greatest likelihood of being adapted and used in military environments...
  46. doi request reprint Circulating bioactive and immunoreactive IGF-I remain stable in women, despite physical fitness improvements after 8 weeks of resistance, aerobic, and combined exercise training
    Bradley C Nindl
    Military Performance Division, The US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 109:112-20. 2010
    ..In terms of reflecting positive anabolic neuromuscular outcomes, these data do not support a role for endocrine-derived IGF-I...
  47. ncbi request reprint A double-blind, placebo-controlled test of 2 d of calorie deprivation: effects on cognition, activity, sleep, and interstitial glucose concentrations
    Harris R Lieberman
    Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Am J Clin Nutr 88:667-76. 2008
    ..Therefore, test meals varying in caloric content, but indistinguishable in sensory characteristics, were formulated using hydrocolloid-based gels as the principal structural component...
  48. doi request reprint Effects of two different eight-week training programs on military physical performance
    Everett A Harman
    U S Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA
    J Strength Cond Res 22:524-34. 2008
    ..Further research would be needed to determine whether weight-based training provides an advantage over a longer training period...
  49. ncbi request reprint Eighty-four hours of sustained operations alter thermoregulation during cold exposure
    John W Castellani
    US Army Research Institute of Environmental Medicine Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 35:175-81. 2003
    ..PURPOSE; This study examined the effects of short-term (3.5 d) sustained military operations (SUSOPS) on thermoregulatory responses to cold stress...
  50. ncbi request reprint Altered secretion of growth hormone and luteinizing hormone after 84 h of sustained physical exertion superimposed on caloric and sleep restriction
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 100:120-8. 2006
    ..During periods of energy deficiency, amplitude modulation of GH and LH pulses may precede alterations in pulse numbers...
  51. ncbi request reprint Correlates of load carriage and obstacle course performance among women
    Clay E Pandorf
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Work 18:179-89. 2002
    ..Maximum number of sit-ups and push-ups, composite score of the Army Physical Fitness Test as well as body height were positively correlated with the speed at which some course segments were traversed...
  52. ncbi request reprint Nocturnal growth hormone secretory dynamics are altered after resistance exercise: deconvolution analysis of 12-hour immunofunctional and immunoreactive isoforms
    Alexander P Tuckow
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA, USA
    Am J Physiol Regul Integr Comp Physiol 291:R1749-55. 2006
    ....
  53. ncbi request reprint Cognition during sustained operations: comparison of a laboratory simulation to field studies
    Harris R Lieberman
    U S Army Research Institute of Environmental Medicine, Natick 01760 5007, USA
    Aviat Space Environ Med 77:929-35. 2006
    ..Our laboratory developed a brief, intense, laboratory-based simulation of a multistressor environment which included sleep loss, continuous physical activity, and food deprivation...
  54. ncbi request reprint Influence of oral contraceptive use on growth hormone in vivo bioactivity following resistance exercise: responses of molecular mass variants
    William J Kraemer
    Human Performance Laboratory, Department of Kinesiology, Department of Physiology and Neurobiology, University of Connecticut Storrs, CT 06269, USA
    Growth Horm IGF Res 18:238-44. 2008
    ..However, OC use only increased biological activity of GH in one of two bioassays. These data demonstrated that GH concentrations at rest and following exercise are assay-dependent...
  55. ncbi request reprint Resistance training improves strength and functional measures in patients with end-stage renal disease
    Samuel Headley
    Springfield College, Pioneer Valley Dialysis Center, Military Performance Division, US Army Research, Springfield, MA 01109, USA
    Am J Kidney Dis 40:355-64. 2002
    ..The current study was designed to examine the effect of 12 weeks of resistance training on strength and functional ability in 10 medically stable hemodialysis patients (age, 42.8 +/- 4.4 years)...
  56. ncbi request reprint Reliability assessment of ballistic jump squats and bench throws
    Joseph A Alemany
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Strength Cond Res 19:33-8. 2005
    ..Slightly greater variability for JS was observed, although the test had high reliability...
  57. doi request reprint Influence of exercise mode and osteogenic index on bone biomarker responses during short-term physical training
    Mark E Lester
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Building 42, Kansas Street, Natick, MA 01760, USA
    Bone 45:768-76. 2009
    ....
  58. doi request reprint Female recruits sustaining stress fractures during military basic training demonstrate differential concentrations of circulating IGF-I system components: a preliminary study
    C A Strohbach
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Growth Horm IGF Res 22:151-7. 2012
    ..This study examined the response of the IGF-I system between female soldiers that sustained a stress fracture (SFX, n=13) during BT and female soldiers who did not (NSFX, n=49)...
  59. ncbi request reprint Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways
    Barry A Spiering
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, Connecticut 06269, USA
    Sports Med 38:527-40. 2008
    ..e. exercise choice, load, volume, rest period lengths, and exercise order) alters the unique 'fingerprint' of the RE stimulus and subsequently modifies the downstream cellular and molecular responses...
  60. doi request reprint Effects of elevated circulating hormones on resistance exercise-induced Akt signaling
    Barry A Spiering
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT 06269, USA
    Med Sci Sports Exerc 40:1039-48. 2008
    ..We hypothesized that elevated circulating hormones would potentiate the signaling response...
  61. ncbi request reprint Influence of the menstrual cycle on proenkephalin peptide F responses to maximal cycle exercise
    William J Kraemer
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT, 06269, USA
    Eur J Appl Physiol 96:581-6. 2006
    ..Pre-exercise arousal mechanisms potentially related to analgesia may also be involved to prepare untrained women for the stress of maximal exercise...
  62. doi request reprint Histological and molecular analysis of the biceps tendon long head post-tenotomy
    Michael Joseph
    Department of Kinesiology, The University of Connecticut, Storrs, Connecticut, USA
    J Orthop Res 27:1379-85. 2009
    ..The intra-articular LHB exhibited histological characteristics of tendinopathy. Protein expression of the intra-articular LHB did not universally display signs of tendinopathy in comparison to the extra-articular portion of the tendon...
  63. ncbi request reprint IGF-I system responses during 12 weeks of resistance training in end-stage renal disease patients
    Bradley C Nindl
    Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Growth Horm IGF Res 14:245-50. 2004
    ..To examine the hypothesis that 12 weeks of resistance training would alter circulating concentrations of IGF-I system components in end-stage renal disease (ESRD) patients...
  64. doi request reprint Elevated endogenous testosterone concentrations potentiate muscle androgen receptor responses to resistance exercise
    Barry A Spiering
    Department of Kinesiology, University of Connecticut, 2095 Hillside Road, Storrs, CT 06269, USA
    J Steroid Biochem Mol Biol 114:195-9. 2009
    ..10) but remained stable during HT (+40%; p=0.17). Muscle AR content at +180 during the HT trial exceeded the corresponding CON value. In conclusion, acute elevations in circulating T potentiated muscle AR content following RE...
  65. ncbi request reprint Effect of alkalosis on plasma epinephrine responses to high intensity cycle exercise in humans
    James O Marx
    Laboratory for Sports Medicine, The Pennsylvania State University, University Park, PA 16802, USA
    Eur J Appl Physiol 87:72-7. 2002
    ..7 (54.4) W P]. The primary finding of this investigation was that orally-induced alkalosis does not significantly affect plasma epinephrine concentrations or performance following 90 s of maximal cycle exercise in untrained men...
  66. ncbi request reprint Changes in muscle hypertrophy in women with periodized resistance training
    William J Kraemer
    Human Performance Laboratory Department of Kinesiology, University of Connecticut, Storrs, CT 06269 1110, USA
    Med Sci Sports Exerc 36:697-708. 2004
    ..Adaptations of arm and thigh muscle hypertrophy to different long-term periodized resistance training programs and the influence of upper body resistance training were examined...
  67. doi request reprint Moderate protein intake improves total and regional body composition and insulin sensitivity in overweight adults
    Paul J Arciero
    Department of Exercise Science, Skidmore College, Saratoga Springs, NY 12866, USA
    Metabolism 57:757-65. 2008
    ..These findings may have practical implications for individuals interested in diets containing elevated dietary protein...
  68. ncbi request reprint Chronic resistance training in women potentiates growth hormone in vivo bioactivity: characterization of molecular mass variants
    William J Kraemer
    Human Performance Laboratory, Dept of Kinesiology, University of Connecticut, Storrs, CT 06269, USA
    Am J Physiol Endocrinol Metab 291:E1177-87. 2006
    ....
  69. ncbi request reprint Effects of resistance training on resting immune parameters in women
    Mary P Miles
    Department of Health and Human Development, Montana State University, Bozeman, MT, USA
    Eur J Appl Physiol 87:506-8. 2002
    ..This was consistent despite differences in the volume of muscle mass trained or the manner of training (power verses hypertrophy)...