Aysegul Nalca

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. pmc ACAM2000: the new smallpox vaccine for United States Strategic National Stockpile
    Aysegul Nalca
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA
    Drug Des Devel Ther 4:71-9. 2010
  2. ncbi request reprint Reemergence of monkeypox: prevalence, diagnostics, and countermeasures
    Aysegul Nalca
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    Clin Infect Dis 41:1765-71. 2005
  3. pmc A characterization of aerosolized Sudan virus infection in African green monkeys, cynomolgus macaques, and rhesus macaques
    Elizabeth E Zumbrun
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA
    Viruses 4:2115-36. 2012
  4. doi request reprint Rabbitpox: a model of airborne transmission of smallpox
    Aysegul Nalca
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    J Gen Virol 92:31-5. 2011
  5. pmc Evaluation of the efficacy of modified vaccinia Ankara (MVA)/IMVAMUNE against aerosolized rabbitpox virus in a rabbit model
    Nicole L Garza
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, United States
    Vaccine 27:5496-504. 2009
  6. pmc Development of a murine model for aerosolized ebolavirus infection using a panel of recombinant inbred mice
    Elizabeth E Zumbrun
    Center for Aerobiological Sciences, U S Army Medical Research Institute of Infectious Diseases USAMRIID, 1425 Porter Street, Fort Detrick, Maryland 21702, USA
    Viruses 4:3468-93. 2012
  7. doi request reprint Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model
    Aysegul Nalca
    Center for Aerobiological Sciences, U S Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, MD, United States
    Antiviral Res 79:121-7. 2008
  8. pmc Application of the Ibis-T5000 pan-Orthopoxvirus assay to quantitatively detect monkeypox viral loads in clinical specimens from macaques experimentally infected with aerosolized monkeypox virus
    Rebecca J Grant
    U S Army Medical Research Institute of Infectious Diseases, 1301 Ditto Avenue, Fort Detrick, MD 21702, USA
    Am J Trop Med Hyg 82:318-23. 2010
  9. pmc Aerosol exposure to Rift Valley fever virus causes earlier and more severe neuropathology in the murine model, which has important implications for therapeutic development
    Christopher Reed
    United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Maryland, USA
    PLoS Negl Trop Dis 7:e2156. 2013

Collaborators

  • Lisa E Hensley
  • Darci R Smith
  • Chris A Whitehouse
  • Mark W Eshoo
  • Dennis Hruby
  • Rangarajan Sampath
  • Anne W Rimoin
  • Robert Jordan
  • Elizabeth E Zumbrun
  • Donald K Nichols
  • Nicole L Garza
  • Christopher Reed
  • Holly A Bloomfield
  • Rebecca J Grant
  • Ashley Keeney
  • Joshua Shamblin
  • Kenny Lin
  • Brian Friedrich
  • Gene Olinger
  • Catherine Wilhelmsen
  • Ginger Donnelly
  • Taylor B Chance
  • Roger D Williams
  • Paige E Harrison
  • Ty C Hunter
  • Paul A Dabisch
  • Reese J Baker
  • Malak Kotb
  • John M Dye
  • Nicholas R Bramel
  • Nourtan F Abdeltawab
  • Scott Zoll
  • Lawrence B Blyn
  • Heather Matthews
  • Carson D Baldwin
  • Josh M Hatkin
  • Diana Fisher
  • Ariane Volkmann
  • Virginia Livingston
  • Paul J Chaplin

Detail Information

Publications10

  1. pmc ACAM2000: the new smallpox vaccine for United States Strategic National Stockpile
    Aysegul Nalca
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA
    Drug Des Devel Ther 4:71-9. 2010
    ..This review of ACAM2000 addresses the production, characterization, clinical trials, and adverse events associated with this new smallpox vaccine...
  2. ncbi request reprint Reemergence of monkeypox: prevalence, diagnostics, and countermeasures
    Aysegul Nalca
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    Clin Infect Dis 41:1765-71. 2005
    ..This has led to fears that monkeypox virus could be used as a bioterrorism agent. Effective prevention relies on limiting the contact with infected patients or animals and limiting the respiratory exposure to infected patients...
  3. pmc A characterization of aerosolized Sudan virus infection in African green monkeys, cynomolgus macaques, and rhesus macaques
    Elizabeth E Zumbrun
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA
    Viruses 4:2115-36. 2012
    ..Overall, the results indicate that the disease course after exposure to aerosolized SUDV is similar for all three species of NHP...
  4. doi request reprint Rabbitpox: a model of airborne transmission of smallpox
    Aysegul Nalca
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA
    J Gen Virol 92:31-5. 2011
    ..This model can therefore be utilized to test drugs and vaccines against variola virus and other aerosolized orthopoxviruses...
  5. pmc Evaluation of the efficacy of modified vaccinia Ankara (MVA)/IMVAMUNE against aerosolized rabbitpox virus in a rabbit model
    Nicole L Garza
    Center for Aerobiological Sciences, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, United States
    Vaccine 27:5496-504. 2009
    ..This study shows that IMVAMUNE can be a very effective vaccine against aerosolized RPXV...
  6. pmc Development of a murine model for aerosolized ebolavirus infection using a panel of recombinant inbred mice
    Elizabeth E Zumbrun
    Center for Aerobiological Sciences, U S Army Medical Research Institute of Infectious Diseases USAMRIID, 1425 Porter Street, Fort Detrick, Maryland 21702, USA
    Viruses 4:3468-93. 2012
    ..Preliminary quantitative trait loci (QTLs) were identified that are likely to harbor genes involved in modulating differential susceptibility to Ebola infection...
  7. doi request reprint Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model
    Aysegul Nalca
    Center for Aerobiological Sciences, U S Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, MD, United States
    Antiviral Res 79:121-7. 2008
    ..e., survival was 67% and 33%, respectively. This work suggests that ST-246 is a very potent antiviral compound against aerosolized rabbitpox in rabbits and should be investigated for further development for all orthopoxvirus diseases...
  8. pmc Application of the Ibis-T5000 pan-Orthopoxvirus assay to quantitatively detect monkeypox viral loads in clinical specimens from macaques experimentally infected with aerosolized monkeypox virus
    Rebecca J Grant
    U S Army Medical Research Institute of Infectious Diseases, 1301 Ditto Avenue, Fort Detrick, MD 21702, USA
    Am J Trop Med Hyg 82:318-23. 2010
    ..This platform provides a new tool for the diagnosis and monitoring of orthopoxviral loads during vaccine or antiviral studies, but also could provide rapid identification during natural outbreaks or bioterrorism attacks...
  9. pmc Aerosol exposure to Rift Valley fever virus causes earlier and more severe neuropathology in the murine model, which has important implications for therapeutic development
    Christopher Reed
    United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Maryland, USA
    PLoS Negl Trop Dis 7:e2156. 2013
    ....