Stephen R Muza

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint Military applications of hypoxic training for high-altitude operations
    Stephen R Muza
    U S Army Research Institute of Environmental Medicine, Natick, MA 02053, USA
    Med Sci Sports Exerc 39:1625-31. 2007
  2. doi request reprint Intermittent hypoxic exposure does not improve sleep at 4300 m
    Juli E Jones
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 9:281-7. 2008
  3. ncbi request reprint Residence at moderate altitude improves ventilatory response to high altitude
    Stephen R Muza
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 75:1042-8. 2004
  4. ncbi request reprint Cysteinyl leukotriene blockade does not prevent acute mountain sickness
    Stephen R Muza
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 75:413-9. 2004
  5. ncbi request reprint Ventilation after supplemental oxygen administration at high altitude
    Stephen R Muza
    US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Wilderness Environ Med 15:18-24. 2004
  6. doi request reprint Altitude preexposure recommendations for inducing acclimatization
    Stephen R Muza
    U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    High Alt Med Biol 11:87-92. 2010
  7. doi request reprint Effect of repeated normobaric hypoxia exposures during sleep on acute mountain sickness, exercise performance, and sleep during exposure to terrestrial altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA 01760, USA
    Am J Physiol Regul Integr Comp Physiol 300:R428-36. 2011
  8. doi request reprint Effect of six days of staging on physiologic adjustments and acute mountain sickness during ascent to 4300 meters
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 10:253-60. 2009
  9. doi request reprint Efficacy of residence at moderate versus low altitude on reducing acute mountain sickness in men following rapid ascent to 4300 m
    Janet E Staab
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 14:13-8. 2013
  10. ncbi request reprint Seven intermittent exposures to altitude improves exercise performance at 4300 m
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 40:141-8. 2008

Detail Information

Publications28

  1. ncbi request reprint Military applications of hypoxic training for high-altitude operations
    Stephen R Muza
    U S Army Research Institute of Environmental Medicine, Natick, MA 02053, USA
    Med Sci Sports Exerc 39:1625-31. 2007
    ..Thus, IHE is a promising approach to provide the benefits of altitude acclimatization to low-altitude-based soldiers before their deployment to high mountainous regions...
  2. doi request reprint Intermittent hypoxic exposure does not improve sleep at 4300 m
    Juli E Jones
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 9:281-7. 2008
    ..Rather, it is likely that the acquired ventilatory acclimatization was lost in the 60 h between the last IHE session and the POST-T altitude exposure...
  3. ncbi request reprint Residence at moderate altitude improves ventilatory response to high altitude
    Stephen R Muza
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 75:1042-8. 2004
    ..This study compared the distribution of arterial oxygen saturation (SaO2) and susceptibility to Acute Mountain Sickness (AMS) in moderate altitude residents (MAR) and low altitude residents (LAR) following rapid ascent to 4056 m...
  4. ncbi request reprint Cysteinyl leukotriene blockade does not prevent acute mountain sickness
    Stephen R Muza
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 75:413-9. 2004
    ..AMS may be a manifestation of hypoxia-induced cerebral edema resulting, in part, from increased capillary permeability...
  5. ncbi request reprint Ventilation after supplemental oxygen administration at high altitude
    Stephen R Muza
    US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Wilderness Environ Med 15:18-24. 2004
    ..The present study assessed the effects of acute hyperoxia on resting-minute ventilation (VE) during altitude acclimatization to 4300 m...
  6. doi request reprint Altitude preexposure recommendations for inducing acclimatization
    Stephen R Muza
    U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    High Alt Med Biol 11:87-92. 2010
    ..The subsequent ascent to high altitude should be scheduled as soon as possible after the last altitude preexposure...
  7. doi request reprint Effect of repeated normobaric hypoxia exposures during sleep on acute mountain sickness, exercise performance, and sleep during exposure to terrestrial altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA 01760, USA
    Am J Physiol Regul Integr Comp Physiol 300:R428-36. 2011
    ..Under HH conditions, the higher sleep Sa(O(2)) may have contributed to a lessening of AMS upon awakening but had no impact on AMS or exercise performance for the remainder of each day...
  8. doi request reprint Effect of six days of staging on physiologic adjustments and acute mountain sickness during ascent to 4300 meters
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 10:253-60. 2009
    ..56) to postSTG (45 +/- 53%; 0.59 +/- 0.43), respectively. These results suggest that modest physiologic adjustments induced by staging for 6 d at 2200 m reduced the incidence and severity of AMS during rapid, high-risk ascent to 4300 m...
  9. doi request reprint Efficacy of residence at moderate versus low altitude on reducing acute mountain sickness in men following rapid ascent to 4300 m
    Janet E Staab
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 14:13-8. 2013
    ....
  10. ncbi request reprint Seven intermittent exposures to altitude improves exercise performance at 4300 m
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 40:141-8. 2008
    ....
  11. doi request reprint Intermittent hypoxic exposure does not improve endurance performance at altitude
    Beth A Beidleman
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 41:1317-25. 2009
    ..This study examined the effect of 1 wk of normobaric intermittent hypoxic exposure (IHE) combined with exercise training on endurance performance at a 4300-m altitude (HA)...
  12. ncbi request reprint Intermittent altitude exposures reduce acute mountain sickness at 4300 m
    Beth A Beidleman
    Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Clin Sci (Lond) 106:321-8. 2004
    ..In conclusion, our findings suggest that 3 weeks of IAE provide an effective alternative to chronic altitude residence for increasing resting ventilation and reducing the incidence and severity of AMS...
  13. ncbi request reprint White blood cell and hormonal responses to 4300 m altitude before and after intermittent altitude exposure
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Clin Sci (Lond) 111:163-9. 2006
    ..This method of pre-acclimatization can therefore be highly recommended for inducing altitude acclimatization without the 'altitude residency' requirement...
  14. doi request reprint Effect of hypohydration and altitude exposure on aerobic exercise performance and acute mountain sickness
    John W Castellani
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, 42 Kansas St, Natick, MA 01760 5007, USA
    J Appl Physiol (1985) 109:1792-800. 2010
    ..07). In conclusion, hypohydration at 3,048 m 1) degrades aerobic performance in an additive manner with that induced by ALT; and 2) did not appear to increase the prevalence/severity of AMS symptoms...
  15. ncbi request reprint Saccadic velocity and pupillary reflexes during acclimatization to altitude (4300 m)
    Allen Cymerman
    U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 76:627-34. 2005
    ....
  16. ncbi request reprint Validation of a shortened electronic version of the environmental symptoms questionnaire
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 8:192-9. 2007
    ..90; p = 0.01), PP48 (k = 0.91; p = 0.01), and PP72 (k = 0.92; p = 0.01) were significant. Our findings suggest that the shortened electronic version can be substituted for the paper and pencil version of the ESQ to assess AMS...
  17. ncbi request reprint Intermittent altitude exposures improve muscular performance at 4,300 m
    Beth A Beidleman
    Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol (1985) 95:1824-32. 2003
    ..IAE may therefore be used as an alternative to chronic altitude residence to facilitate improvements in muscular performance in athletes, soldiers, mountaineers, shift workers, and others that are deployed to altitude...
  18. doi request reprint Effectiveness of preacclimatization strategies for high-altitude exposure
    Charles S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Exerc Sport Sci Rev 41:55-63. 2013
    ..Strategies using hypobaric chambers or true altitude were much more effective overall than those using normobaric hypoxia (breathing, <20.9% oxygen)...
  19. ncbi request reprint Exercise performance of sea-level residents at 4300 m after 6 days at 2200 m
    Charles S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 80:955-61. 2009
    ..g., 4300 m). Whether staging also benefits endurance performance has not yet been scientifically evaluated...
  20. ncbi request reprint Performance during simple and complex military psychomotor tasks at various altitudes
    Mark A Kryskow
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Aviat Space Environ Med 84:1147-52. 2013
    ....
  21. doi request reprint Predictive models of acute mountain sickness after rapid ascent to various altitudes
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 45:792-800. 2013
    ..Despite decades of research, no predictive models of acute mountain sickness (AMS) exist, which identify the time course of AMS severity and prevalence following rapid ascent to various altitudes...
  22. ncbi request reprint Substrate oxidation is altered in women during exercise upon acute altitude exposure
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 34:430-7. 2002
    ..The purpose of this study was to determine whether substrate oxidation during submaximal exercise in women is affected by an acute exposure to 4300-m altitude and menstrual cycle phase...
  23. ncbi request reprint Changes in ventilatory threshold at high altitude: effect of antioxidants
    Andrew W Subudhi
    Department of Biology, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA
    Med Sci Sports Exerc 38:1425-31. 2006
    ..To investigate the effects of prolonged hypoxia and antioxidant supplementation on ventilatory threshold (VT) during high-altitude (HA) exposure (4300 m)...
  24. ncbi request reprint Cytokine responses at high altitude: effects of exercise and antioxidants at 4300 m
    Todd A Hagobian
    Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304 1290, USA
    Med Sci Sports Exerc 38:276-85. 2006
    ....
  25. ncbi request reprint Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction
    Kimberly E Barnholt
    Clinical Studies Unit, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA
    Am J Physiol Endocrinol Metab 290:E1078-88. 2006
    ..Such suppression results in the preservation of energy stores but may sacrifice the facilitation of oxygen delivery and the use of oxygen-efficient fuels...
  26. ncbi request reprint Statistical models of acute mountain sickness
    Richard D Vann
    Center for Hyperbaric Medicine and Environmental Physiology, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA
    High Alt Med Biol 6:32-42. 2005
    ....
  27. ncbi request reprint Antioxidant supplementation does not attenuate oxidative stress at high altitude
    Andrew W Subudhi
    VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304 1290, USA
    Aviat Space Environ Med 75:881-8. 2004
    ..Hypobaric hypoxia and heightened metabolic rate increase free radical production...
  28. ncbi request reprint Epidemiological modeling of acute mountain sickness (AMS). A prospective data collection standard
    Richard D Vann
    Center for Hyperbaric Medicine and Environmental Physiology, Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Adv Exp Med Biol 543:355-8. 2003