Arthur Lyons

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint A Phase 2 study of a purified, inactivated virus vaccine to prevent Japanese encephalitis
    Arthur Lyons
    Department of Virus Diseases, Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Vaccine 25:3445-53. 2007
  2. doi request reprint A double-blind, placebo-controlled study of the safety and immunogenicity of live, oral type 4 and type 7 adenovirus vaccines in adults
    Arthur Lyons
    Department of Virus Diseases, Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Vaccine 26:2890-8. 2008
  3. pmc Genome sequences of human adenovirus 14 isolates from mild respiratory cases and a fatal pneumonia, isolated during 2006-2007 epidemics in North America
    Huo Shu H Houng
    Walter Reed Army Institute of Research, Silver Spring, 20910, USA
    Respir Res 11:116. 2010
  4. doi request reprint Emergent 2009 influenza A(H1N1) viruses containing HA D222N mutation associated with severe clinical outcomes in the Americas
    Huo Shu H Houng
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Clin Virol 53:12-5. 2012
  5. pmc Multiplexed Luminex xMAP assay for detection and identification of five adenovirus serotypes associated with epidemics of respiratory disease in adults
    Cicely Washington
    Division of Viral Diseases, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    J Clin Microbiol 48:2217-22. 2010

Detail Information

Publications5

  1. ncbi request reprint A Phase 2 study of a purified, inactivated virus vaccine to prevent Japanese encephalitis
    Arthur Lyons
    Department of Virus Diseases, Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Vaccine 25:3445-53. 2007
    ..JE-PIV was well tolerated, resulted in high seroconversion rates [Day 56 (primary endpoint); 95-100%] and induced enduring immune responses up to 2 years after vaccination. Expanded Phase 3 trials are planned...
  2. doi request reprint A double-blind, placebo-controlled study of the safety and immunogenicity of live, oral type 4 and type 7 adenovirus vaccines in adults
    Arthur Lyons
    Department of Virus Diseases, Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Vaccine 26:2890-8. 2008
    ..3) while 63% seroconverted to ADV-7 (GMT 51.1) by Day 28. The new ADV-4 and ADV-7 vaccines were safe and induced a good immune response in the study population. Expanded trials for safety and efficacy are in progress...
  3. pmc Genome sequences of human adenovirus 14 isolates from mild respiratory cases and a fatal pneumonia, isolated during 2006-2007 epidemics in North America
    Huo Shu H Houng
    Walter Reed Army Institute of Research, Silver Spring, 20910, USA
    Respir Res 11:116. 2010
    ..Some outbreaks have been relatively mild, with low rates of progression beyond uncomplicated FRI, while other outbreaks have involved high rates of more serious outcomes...
  4. doi request reprint Emergent 2009 influenza A(H1N1) viruses containing HA D222N mutation associated with severe clinical outcomes in the Americas
    Huo Shu H Houng
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Clin Virol 53:12-5. 2012
    ..Genetically, the haemagglutinin (HA) of this sub-clade was distinct from HAs found in viruses associated with severe outbreaks in 2010 from the United Kingdom and from other global specimens isolated earlier in the season...
  5. pmc Multiplexed Luminex xMAP assay for detection and identification of five adenovirus serotypes associated with epidemics of respiratory disease in adults
    Cicely Washington
    Division of Viral Diseases, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    J Clin Microbiol 48:2217-22. 2010
    ..This multiplexed assay can be expanded to include more serotypes and will allow broad and rapid detection and identification of adenoviral serotypes in a high-throughput environment...