Juliann G Kiang

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi Observation of the low frequency vibrational modes of bacteriophage M13 in water by Raman spectroscopy
    K T Tsen
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Virol J 3:79. 2006
  2. ncbi External bioenergy increases intracellular free calcium concentration and reduces cellular response to heat stress
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    J Investig Med 50:38-45. 2002
  3. ncbi Biology of hypoxia
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Chin J Physiol 49:223-33. 2006
  4. ncbi Geldanamycin prevents hemorrhage-induced ATP loss by overexpressing inducible HSP70 and activating pyruvate dehydrogenase
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Am J Physiol Gastrointest Liver Physiol 291:G117-27. 2006
  5. ncbi External bioenergy-induced increases in intracellular free calcium concentrations are mediated by Na+/Ca2+ exchanger and L-type calcium channel
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Room 1N07, Silver Spring, MD 20910 7500, USA
    Mol Cell Biochem 271:51-9. 2005
  6. ncbi Inducible heat shock protein 70 kD and inducible nitric oxide synthase in hemorrhage/resuscitation-induced injury
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Cell Res 14:450-9. 2004
  7. ncbi Resuscitation with lactated Ringer solution limits the expression of molecular events associated with lung injury after hemorrhage
    Juliann G Kiang
    Division of Military Casualty Research, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Rm 1N07, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 98:550-6. 2005
  8. ncbi Geldanamycin treatment inhibits hemorrhage-induced increases in KLF6 and iNOS expression in unresuscitated mouse organs: role of inducible HSP70
    Juliann G Kiang
    Department of Cellular Injury, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 97:564-9. 2004
  9. ncbi NaCN-induced chemical hypoxia is associated with altered gene expression
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Mol Cell Biochem 254:211-6. 2003
  10. ncbi Constitutive NO synthase regulates the Na+/Ca2+ exchanger in human T cells: role of [Ca2+]i and tyrosine phosphorylation
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Room 1N07, Silver Spring, MD 20910 7500, USA
    J Cell Biochem 89:1030-43. 2003

Collaborators

Detail Information

Publications18

  1. ncbi Observation of the low frequency vibrational modes of bacteriophage M13 in water by Raman spectroscopy
    K T Tsen
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Virol J 3:79. 2006
    ..For example, rod-shaped viruses such as the M13 phage and tobacco mosaic virus have been successfully used as biological templates for the synthesis of semiconductor and metallic nanowires...
  2. ncbi External bioenergy increases intracellular free calcium concentration and reduces cellular response to heat stress
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    J Investig Med 50:38-45. 2002
    ....
  3. ncbi Biology of hypoxia
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Chin J Physiol 49:223-33. 2006
    ..Therefore, iNOS inhibition may be a novel mechanism for protection from hypoxia-induced injury and cell death...
  4. ncbi Geldanamycin prevents hemorrhage-induced ATP loss by overexpressing inducible HSP70 and activating pyruvate dehydrogenase
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Am J Physiol Gastrointest Liver Physiol 291:G117-27. 2006
    ..We conclude that agents able to increase the expression of HSP70 and PDH may be of value in reducing pathology resulting from hemorrhage-associated ATP loss...
  5. ncbi External bioenergy-induced increases in intracellular free calcium concentrations are mediated by Na+/Ca2+ exchanger and L-type calcium channel
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Room 1N07, Silver Spring, MD 20910 7500, USA
    Mol Cell Biochem 271:51-9. 2005
    ..The increase in [Ca2+]i is mediated by activation of Na+/Ca2+ exchangers and opening of L-type voltage-gated Ca2+ channels...
  6. ncbi Inducible heat shock protein 70 kD and inducible nitric oxide synthase in hemorrhage/resuscitation-induced injury
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Cell Res 14:450-9. 2004
    ..HSP-70i is found to couple to iNOS and its transcription factor. Therefore, the complex formation between HSP-70i and iNOS may be a novel mechanism for protection from hemorrhage/resuscitation-induced injury...
  7. ncbi Resuscitation with lactated Ringer solution limits the expression of molecular events associated with lung injury after hemorrhage
    Juliann G Kiang
    Division of Military Casualty Research, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Rm 1N07, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 98:550-6. 2005
    ..Our results demonstrate that resuscitation with LR can reverse the expression of genes and their products that are thought to contribute to hemorrhage-induced lung injury...
  8. ncbi Geldanamycin treatment inhibits hemorrhage-induced increases in KLF6 and iNOS expression in unresuscitated mouse organs: role of inducible HSP70
    Juliann G Kiang
    Department of Cellular Injury, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 97:564-9. 2004
    ..These results suggest that GA may be therapeutically useful for reducing hemorrhage-induced injury when used as a presurgical treatment or when added to resuscitation fluids...
  9. ncbi NaCN-induced chemical hypoxia is associated with altered gene expression
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Mol Cell Biochem 254:211-6. 2003
    ....
  10. ncbi Constitutive NO synthase regulates the Na+/Ca2+ exchanger in human T cells: role of [Ca2+]i and tyrosine phosphorylation
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Room 1N07, Silver Spring, MD 20910 7500, USA
    J Cell Biochem 89:1030-43. 2003
    ..This process is related to increased expression of Fas/CD95 on the cell surface, which might explain the apoptotic diathesis of lymphocytes after heat stress...
  11. ncbi Genistein inhibits herbimycin A-induced over-expression of inducible heat shock protein 70 kDa
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Mol Cell Biochem 245:191-9. 2003
    ..The herbimycin A-induced increase in HSP-70i protected cells from hypoxia injury...
  12. ncbi N(omega)-nitro-L-arginine inhibits inducible HSP-70 via Ca(2+), PKC, and PKA in human intestinal epithelial T84 cells
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring 20910 7500, USA
    Am J Physiol Gastrointest Liver Physiol 282:G415-23. 2002
    ..These results suggest that L-NNA inhibits HSP-70i by reducing [Ca(2+)](i) and decreasing PKC and PKA activity, thereby blocking HSF1 translocation from the cytosol to the nucleus...
  13. ncbi Increased caspase-3 expression and activity contribute to reduced CD3zeta expression in systemic lupus erythematosus T cells
    Sandeep Krishnan
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD 20910-7500, USA
    J Immunol 175:3417-23. 2005
    ..We conclude that caspase-3 inhibitors can normalize SLE T cell function by limiting the excessive digestion of CD3zeta-chain and suggest that such molecules can be considered in the treatment of this disease...
  14. ncbi Androstenediol inhibits the trauma-hemorrhage-induced increase in caspase-3 by downregulating the inducible nitric oxide synthase pathway
    Juliann G Kiang
    Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    J Appl Physiol 102:933-41. 2007
    ..AED can potentially be a useful adjuvant for limiting liver apoptosis following T-H shock...
  15. ncbi Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat
    James L Atkins
    Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Shock 30:411-6. 2008
    ....
  16. ncbi Heat stress protection against mesenteric I/R-induced alterations in intestinal mucosa in rats
    Sherry D Fleming
    Department of Cellular Injury, Walter Reed Army Medical Institute of Research, Silver Spring, Maryland, USA
    J Appl Physiol 92:2600-7. 2002
    ..Thus induction of heat shock protein 70 is associated with the preservation of mucosal architecture and attenuation of some specific functional alterations induced by I/R...
  17. ncbi Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: role of inducible nitric oxide synthase
    Juliann G Kiang
    Scientific Research Department, Armed Forces Radiobiology Research Institute, BLDG 46, Rm 2423, Uniformed Services University of the Health Sciences, 8901 Wisconsin Ave, Bethesda, MD 20889 5603, USA
    J Appl Physiol 103:1045-55. 2007
    ..Geldanamycin, therefore, may prove useful as an adjuvant in fluids used to treat patients suffering blood loss...
  18. ncbi Inhibition of inducible nitric-oxide synthase protects human T cells from hypoxia-induced apoptosis
    Juliann G Kiang
    Armed Forces Radiobiology Research Institute, BLDG 46, Room 2423, 8901 Wisconsin Ave, Bethesda, MD 20889 5603, USA
    Mol Pharmacol 73:738-47. 2008
    ..These data suggest iNOS-mediated NO produced endogenously in the T cell alters overall T-cell function and results in apoptosis. Proper control of iNOS expressed in the T cell may represent a useful approach to immunomodulation...