Bijan S Kheirabadi

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint Comparative study of the hemostatic efficacy of a new human fibrin sealant: is an antifibrinolytic agent necessary?
    Bijan S Kheirabadi
    American Red Cross, Holland Laboratory, Rockville, Maryland 20855, USA
    J Trauma 52:1107-15. 2002
  2. doi request reprint Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 66:316-26; discussion 327-8. 2009
  3. doi request reprint Effects of synthetic versus natural colloid resuscitation on inducing dilutional coagulopathy and increasing hemorrhage in rabbits
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma 64:1218-28; discussion 1228-9. 2008
  4. ncbi request reprint In vitro effect of activated recombinant factor VII (rFVIIa) on coagulation properties of human blood at hypothermic temperatures
    Bijan S Kheirabadi
    Division of Damage Control Resuscitation, US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 63:1079-86. 2007
  5. ncbi request reprint High-pressure fibrin sealant foam: an effective hemostatic agent for treating severe parenchymal hemorrhage
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
    J Surg Res 144:145-50. 2008
  6. ncbi request reprint In vivo bleeding time and in vitro thrombelastography measurements are better indicators of dilutional hypothermic coagulopathy than prothrombin time
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam, Houston, Texas 78234 6315, USA
    J Trauma 62:1352-9; discussion 1359-61. 2007
  7. ncbi request reprint The potential utility of fibrin sealant dressing in repair of vascular injury in swine
    Bijan S Kheirabadi
    United States Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 62:94-103. 2007
  8. ncbi request reprint Assessment of the thrombogenic effect of fibrin sealant dressing in a vascular surgery model in rabbits
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Invest Surg 19:387-96. 2006
  9. ncbi request reprint Hemostatic efficacy of two advanced dressings in an aortic hemorrhage model in Swine
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 8234 6315, USA
    J Trauma 59:25-34; discussion 34-5. 2005
  10. doi request reprint Effect of hemodilution on coagulation and recombinant factor VIIa efficacy in human blood in vitro
    Daniel N Darlington
    Damage Control Resuscitation and Blood Programs, US Army Institute of Surgical Research, San Antonio, Texas 78234 6315, USA
    J Trauma 71:1152-63. 2011

Detail Information

Publications26

  1. ncbi request reprint Comparative study of the hemostatic efficacy of a new human fibrin sealant: is an antifibrinolytic agent necessary?
    Bijan S Kheirabadi
    American Red Cross, Holland Laboratory, Rockville, Maryland 20855, USA
    J Trauma 52:1107-15. 2002
    ..The need for addition of an antifibrinolytic agent was assessed under normal and high-fibrinolytic conditions...
  2. doi request reprint Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 66:316-26; discussion 327-8. 2009
    ..The new products were compared with the most advanced forms of HC and QC products...
  3. doi request reprint Effects of synthetic versus natural colloid resuscitation on inducing dilutional coagulopathy and increasing hemorrhage in rabbits
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma 64:1218-28; discussion 1228-9. 2008
    ..We investigated the effects of resuscitation with this fluid, as well as other colloids, on coagulation and uncontrolled bleeding in rabbits subjected to a splenic injury...
  4. ncbi request reprint In vitro effect of activated recombinant factor VII (rFVIIa) on coagulation properties of human blood at hypothermic temperatures
    Bijan S Kheirabadi
    Division of Damage Control Resuscitation, US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 63:1079-86. 2007
    ..This study investigated the effects of hypothermia on clotting and the potential benefit of rFVIIa administration on blood coagulation at different hypothermic temperatures...
  5. ncbi request reprint High-pressure fibrin sealant foam: an effective hemostatic agent for treating severe parenchymal hemorrhage
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
    J Surg Res 144:145-50. 2008
    ..The purpose of this study was to formulate a fibrin sealant foam (FSF) able to control severe parenchymal bleeding without compression or vascular control...
  6. ncbi request reprint In vivo bleeding time and in vitro thrombelastography measurements are better indicators of dilutional hypothermic coagulopathy than prothrombin time
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam, Houston, Texas 78234 6315, USA
    J Trauma 62:1352-9; discussion 1359-61. 2007
    ..5. However, the utility of these values as a screening test is unknown. We examined different coagulation tests to determine the best predictor of coagulopathic bleeding and mortality in a small animal hemorrhage model...
  7. ncbi request reprint The potential utility of fibrin sealant dressing in repair of vascular injury in swine
    Bijan S Kheirabadi
    United States Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 62:94-103. 2007
    ..The objective of this study was to determine the effective duration of FSD hemostatic function in vivo and to examine its potential utility for definitive repair of a major arterial injury in swine...
  8. ncbi request reprint Assessment of the thrombogenic effect of fibrin sealant dressing in a vascular surgery model in rabbits
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Invest Surg 19:387-96. 2006
    ..It may also allow healing of minor venous defects, but cannot replace conventional surgical techniques (suturing) for permanent repair of arterial damages...
  9. ncbi request reprint Hemostatic efficacy of two advanced dressings in an aortic hemorrhage model in Swine
    Bijan S Kheirabadi
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 8234 6315, USA
    J Trauma 59:25-34; discussion 34-5. 2005
    ....
  10. doi request reprint Effect of hemodilution on coagulation and recombinant factor VIIa efficacy in human blood in vitro
    Daniel N Darlington
    Damage Control Resuscitation and Blood Programs, US Army Institute of Surgical Research, San Antonio, Texas 78234 6315, USA
    J Trauma 71:1152-63. 2011
    ..This study evaluates the effect of hemodilution by various common resuscitation fluids, and the efficacy of activated recombinant factor VII (rFVIIa) on coagulation parameters in human blood in vitro...
  11. doi request reprint A novel biologic hemostatic dressing (fibrin patch) reduces blood loss and resuscitation volume and improves survival in hypothermic, coagulopathic Swine with grade V liver injury
    Angel V Delgado
    US Army Institute of Surgical Research, San Antonio, Texas, USA
    J Trauma 64:75-80. 2008
    ..This study evaluated the efficacy of a biologic hemostatic fibrin patch (FP) to control coagulopathic bleeding and prevent death in a porcine model of severe liver injury with hemodilution and hypothermia...
  12. ncbi request reprint Comparison of hemorrhage control agents applied to lethal extremity arterial hemorrhages in swine
    Eric M Acheson
    US Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA
    J Trauma 59:865-74; discussion 874-5. 2005
    ..Our objective was to evaluate the hemostatic efficacy of these three products in a model of severe extremity arterial hemorrhage that could not be stopped by standard gauze treatment...
  13. doi request reprint Determination of efficacy of new hemostatic dressings in a model of extremity arterial hemorrhage in swine
    Bijan S Kheirabadi
    Damage Control Resuscitation Division, US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
    J Trauma 67:450-9; discussion 459-60. 2009
    ..In this study, four new dressings (preselected) that are more suitable for battlefield application were evaluated. The efficacy and acute safety of the dressings were tested in our standard arterial hemorrhage model...
  14. doi request reprint Safety evaluation of new hemostatic agents, smectite granules, and kaolin-coated gauze in a vascular injury wound model in swine
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Ft Sam Houston, Texas, USA
    J Trauma 68:269-78. 2010
    ..Thus, we investigated the thromboembolic risk of using WS when compared with kaolin-coated gauze, Combat Gauze (CG); or regular gauze, Kerlix (KX) to treat an external wound with vascular injuries in pigs...
  15. ncbi request reprint Structural design of the dry fibrin sealant dressing and its impact on the hemostatic efficacy of the product
    Anthony E Pusateri
    US Army Institute of Surgical Research, Fort Sam Houston, San Antonio, Texas 78234 6315, USA
    J Biomed Mater Res B Appl Biomater 70:114-21. 2004
    ..The structural design of DFSD-2 did not meet the efficacy requirement for release of the product. The subsequent change incorporated in DFSD-3 improved all hemostatic parameters of the dressings equal to those of the prototype product...
  16. doi request reprint Initial resuscitation with plasma and other blood components reduced bleeding compared to hetastarch in anesthetized swine with uncontrolled splenic hemorrhage
    Jill L Sondeen
    US Army Institute of Surgical Research, Fort Sam, Houston, Texas 78234 6315, USA
    Transfusion 51:779-92. 2011
    ..The purpose of this study was to evaluate resuscitation with either blood components or conventional fluids on coagulation and blood loss...
  17. doi request reprint Coagulation changes to systemic acidosis and bicarbonate correction in swine
    Daniel N Darlington
    Damage Control Resuscitation Program, US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 71:1271-7. 2011
    ....
  18. doi request reprint Negative-pressure wound therapy: a hemostatic adjunct for control of coagulopathic hemorrhage in large soft tissue wounds
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma Acute Care Surg 73:1188-94. 2012
    ..We investigated the potential hemostatic benefit of negative-pressure wound therapy for control of refractory hemorrhage in a soft tissue wound model in swine...
  19. doi request reprint Development of a standard swine hemorrhage model for efficacy assessment of topical hemostatic agents
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Ft Sam Houston, Texas, USA
    J Trauma 71:S139-46. 2011
    ..The aim of this study was to recommend a standard hemorrhage model for efficacy testing acceptable by most investigators in the field and avoid contradictory and duplicative efforts by different laboratories...
  20. ncbi request reprint Making sense of the preclinical literature on advanced hemostatic products
    Anthony E Pusateri
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, and the Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    J Trauma 60:674-82. 2006
    ..Mission and training requirements will dictate the use of these products by military and civilian prehospital care providers...
  21. ncbi request reprint Vented versus unvented chest seals for treatment of pneumothorax and prevention of tension pneumothorax in a swine model
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, San Antonio, Texas, USA
    J Trauma Acute Care Surg 75:150-6. 2013
    ..Since no supporting data exist, we compared the efficacy of a preferred unvented with that of a vented CS in a novel swine model of pneumothorax (PTx)...
  22. doi request reprint In vivo assessment of the Combat Ready Clamp to control junctional hemorrhage in swine
    Bijan S Kheirabadi
    US Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma Acute Care Surg 74:1260-5. 2013
    ..The Combat Ready Clamp (CRoC) has been developed and deployed for treating junctional hemorrhage on the battlefield. This study examined the efficacy of CRoC and its acute effects in an animal model...
  23. doi request reprint Toxicity of aluminum silicates used in hemostatic dressings toward human umbilical veins endothelial cells, HeLa cells, and RAW267.4 mouse macrophages
    Phillip D Bowman
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 71:727-32. 2011
    ..This study investigated the cellular toxicity of WS in different cell types that may be exposed to this mineral and compared the results with other minerals such as bentonite, kaolin, and QuikClot ACS+ (QC+)...
  24. pmc Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time
    Myung S Park
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma 67:266-75; discussion 275-6. 2009
    ..We hypothesized that a hypercoagulable state exists in patients early after severe injury and that the pattern of clotting and fibrinolysis are similar between burned and nonburn trauma patients...
  25. doi request reprint Arterial blood gases, electrolytes, and metabolic indices associated with hemorrhagic shock: inter- and intrainbred rat strain variation
    Rajiv Rose
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA
    J Appl Physiol (1985) 114:1165-73. 2013
    ..We speculate that whereas genetic differences may be responsible for interstrain variation, individual-specific epigenetic processes (e.g., DNA methylation) may be partly responsible for both inter- and intrastrain ABM variation...
  26. ncbi request reprint Comparative study of the efficacy of the common topical hemostatic agents with fibrin sealant in a rabbit aortic anastomosis model
    Bijan S Kheirabadi
    Holland Laboratory, American Red Cross, Rockville, MD 20855, USA
    J Surg Res 106:99-107. 2002
    ..The purpose of this study was to compare the hemostatic efficacy of the common surgical hemostatic agents with fibrin sealant (FS) and to assess their functional strength to secure hemostasis in lieu of placing additional sutures...