Nikolai V Gorbunov

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi Establishment of a novel clonal murine bone marrow stromal cell line for assessment of p53 responses to genotoxic stress
    Nikolai V Gorbunov
    Pacific Northwest National Laboratory, Richland, WA, USA
    Toxicology 179:257-66. 2002
  2. ncbi Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury
    Nikolai V Gorbunov
    Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    Antioxid Redox Signal 9:483-95. 2007
  3. ncbi Pro-inflammatory alterations and status of blood plasma iron in a model of blast-induced lung trauma
    N V Gorbunov
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Int J Immunopathol Pharmacol 18:547-56. 2005
  4. ncbi Inflammatory leukocytes and iron turnover in experimental hemorrhagic lung trauma
    Nikolai V Gorbunov
    Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Exp Mol Pathol 80:11-25. 2006
  5. ncbi Assessment of inflammatory response and sequestration of blood iron transferrin complexes in a rat model of lung injury resulting from exposure to low-frequency shock waves
    Nikolai V Gorbunov
    Department of Respiratory Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Crit Care Med 32:1028-34. 2004
  6. ncbi Interplay between high energy impulse noise (blast) and antioxidants in the lung
    Nabil M Elsayed
    Department of Respiratory Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Toxicology 189:63-74. 2003
  7. ncbi Ferrous iron is found in mesenteric lymph bound to TIMP-2 following hemorrhage/resuscitation
    James L Atkins
    Closed Head Brain Injury Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    Biometals 24:279-89. 2011
  8. ncbi Electron paramagnetic resonance analysis of transferrin-bound iron in animal models of blunt trauma
    Nikolai V Gorbunov
    Department of Respiratory Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    J Trauma 54:574-83. 2003
  9. ncbi Brisk production of nitric oxide and associated formation of S-nitrosothiols in early hemorrhage
    James L Atkins
    Division of Military Casualty Research, Walter Reed Army Institute of Research, Bldg 503, Rm 1N80, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 100:1267-77. 2006
  10. ncbi Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat
    James L Atkins
    Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Shock 30:411-6. 2008

Detail Information

Publications13

  1. ncbi Establishment of a novel clonal murine bone marrow stromal cell line for assessment of p53 responses to genotoxic stress
    Nikolai V Gorbunov
    Pacific Northwest National Laboratory, Richland, WA, USA
    Toxicology 179:257-66. 2002
    ....
  2. ncbi Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury
    Nikolai V Gorbunov
    Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    Antioxid Redox Signal 9:483-95. 2007
    ..The studies suggested that a part of the proinflammatory action of iron in the lung resulted from its stimulation of the redox-sensitive factors...
  3. ncbi Pro-inflammatory alterations and status of blood plasma iron in a model of blast-induced lung trauma
    N V Gorbunov
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Int J Immunopathol Pharmacol 18:547-56. 2005
    ..We conclude that EPR monitoring of blood (Fe3+)TRF can be a useful approach for assessment of systemic pro-inflammatory alterations due to SW-induced lung injury...
  4. ncbi Inflammatory leukocytes and iron turnover in experimental hemorrhagic lung trauma
    Nikolai V Gorbunov
    Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Exp Mol Pathol 80:11-25. 2006
    ....
  5. ncbi Assessment of inflammatory response and sequestration of blood iron transferrin complexes in a rat model of lung injury resulting from exposure to low-frequency shock waves
    Nikolai V Gorbunov
    Department of Respiratory Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Crit Care Med 32:1028-34. 2004
    ....
  6. ncbi Interplay between high energy impulse noise (blast) and antioxidants in the lung
    Nabil M Elsayed
    Department of Respiratory Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Toxicology 189:63-74. 2003
    ..In addition, it suggests a role for endogenous nitric oxide in the injury. This report reviews experimental evidence of BLAST-induced antioxidant depletion, and the potential benefit from antioxidant supplementation before exposure...
  7. ncbi Ferrous iron is found in mesenteric lymph bound to TIMP-2 following hemorrhage/resuscitation
    James L Atkins
    Closed Head Brain Injury Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    Biometals 24:279-89. 2011
    ..In summary, there is a large increase in extracellular ferrous iron in the gut in H/R demonstrating dysregulation of iron homeostasis. We have identified, for the first time, the binding of extracellular iron to TIMP-2...
  8. ncbi Electron paramagnetic resonance analysis of transferrin-bound iron in animal models of blunt trauma
    Nikolai V Gorbunov
    Department of Respiratory Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    J Trauma 54:574-83. 2003
    ....
  9. ncbi Brisk production of nitric oxide and associated formation of S-nitrosothiols in early hemorrhage
    James L Atkins
    Division of Military Casualty Research, Walter Reed Army Institute of Research, Bldg 503, Rm 1N80, 503 Robert Grant Ave, Silver Spring, MD 20910 7500, USA
    J Appl Physiol 100:1267-77. 2006
    ..The results indicate that the initial compensatory response to H is more complicated than previously realized, and it involves an orchestrated balance between intense vasoconstrictor and vasodilatory components...
  10. ncbi Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat
    James L Atkins
    Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Shock 30:411-6. 2008
    ....
  11. ncbi Significant pulmonary response to a brief high-level, nose-only nitrogen dioxide exposure: an interspecies dosimetry perspective
    Nabil M Elsayed
    Department of Respiratory Research, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    Toxicol Appl Pharmacol 184:1-10. 2002
    ..This raises a question about interspecies dosimetry and species-specific responses when animal data are extrapolated to humans and used for safety standard setting, particularly with high-level brief exposures...
  12. ncbi Pulmonary biochemical and histological alterations after repeated low-level blast overpressure exposures
    Nabil M Elsayed
    Department of Scientific Affairs, Hurley Consulting Associates, Chatham, New Jersey 07928, USA
    Toxicol Sci 95:289-96. 2007
    ..These observations have biological and occupational implications, and emphasize the need for protection from low-level BOP, and for prompt treatment within the first hour following BOP exposure...
  13. ncbi Redox activation of Ref-1 potentiates cell survival following myocardial ischemia reperfusion injury
    Narasimman Gurusamy
    Cardiovascular Research Center, University of Connecticut School of Medicine, Farmington, CT 06030 1110, USA
    Free Radic Biol Med 43:397-407. 2007
    ....