Xiugong Gao

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. pmc Inhibition of sulfur mustard-induced cytotoxicity and inflammation by the macrolide antibiotic roxithromycin in human respiratory epithelial cells
    Xiugong Gao
    Section of Molecular Biology, Department of Biology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    BMC Cell Biol 8:17. 2007
  2. doi request reprint Macrolide antibiotics improve chemotactic and phagocytic capacity as well as reduce inflammation in sulfur mustard-exposed monocytes
    Xiugong Gao
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Pulm Pharmacol Ther 23:97-106. 2010
  3. doi request reprint Suppression of inducible nitric oxide synthase expression and nitric oxide production by macrolide antibiotics in sulfur mustard-exposed airway epithelial cells
    Xiugong Gao
    Department of Biology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Basic Clin Pharmacol Toxicol 103:255-61. 2008
  4. doi request reprint Pathological studies on the protective effect of a macrolide antibiotic, roxithromycin, against sulfur mustard inhalation toxicity in a rat model
    Xiugong Gao
    Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
    Toxicol Pathol 39:1056-64. 2011
  5. doi request reprint Toxicogenomic Studies of Human Neural Cells Following Exposure to Organophosphorus Chemical Warfare Nerve Agent VX
    Xiugong Gao
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA
    Neurochem Res 38:916-34. 2013
  6. pmc An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines
    Peng Zhang
    Division of Experimental Therapeutics and Division of Pathology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Am J Trop Med Hyg 88:1138-45. 2013

Detail Information

Publications6

  1. pmc Inhibition of sulfur mustard-induced cytotoxicity and inflammation by the macrolide antibiotic roxithromycin in human respiratory epithelial cells
    Xiugong Gao
    Section of Molecular Biology, Department of Biology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    BMC Cell Biol 8:17. 2007
    ..We suggest that the influence of roxithromycin on SM-induced inflammatory reaction could play an important therapeutic role in the cytotoxicity exerted by this toxicant...
  2. doi request reprint Macrolide antibiotics improve chemotactic and phagocytic capacity as well as reduce inflammation in sulfur mustard-exposed monocytes
    Xiugong Gao
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Pulm Pharmacol Ther 23:97-106. 2010
    ....
  3. doi request reprint Suppression of inducible nitric oxide synthase expression and nitric oxide production by macrolide antibiotics in sulfur mustard-exposed airway epithelial cells
    Xiugong Gao
    Department of Biology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Basic Clin Pharmacol Toxicol 103:255-61. 2008
    ..These results suggest that macrolide antibiotics may serve as potential vesicant respiratory therapeutics through mechanisms independent of their antibacterial activity...
  4. doi request reprint Pathological studies on the protective effect of a macrolide antibiotic, roxithromycin, against sulfur mustard inhalation toxicity in a rat model
    Xiugong Gao
    Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
    Toxicol Pathol 39:1056-64. 2011
    ..001 and p < .05, respectively) from the untreated group. These results suggest that roxithromycin protects against some damages associated with SM injury in the lung, particularly in the upper respiratory tract...
  5. doi request reprint Toxicogenomic Studies of Human Neural Cells Following Exposure to Organophosphorus Chemical Warfare Nerve Agent VX
    Xiugong Gao
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD, 20910, USA
    Neurochem Res 38:916-34. 2013
    ..These results provide useful information valuable in developing suitable antidotes for more effective prevention and treatment of, as well as in developing biomarkers for, VX-induced chronic neurotoxicity...
  6. pmc An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines
    Peng Zhang
    Division of Experimental Therapeutics and Division of Pathology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Am J Trop Med Hyg 88:1138-45. 2013
    ..These results suggest that this model is suitable for evaluation of selected 8-AQ type candidate antimalarial drugs for their hemolytic potential...