C S Fulco

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. doi request reprint Effectiveness of preacclimatization strategies for high-altitude exposure
    Charles S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Exerc Sport Sci Rev 41:55-63. 2013
  2. ncbi request reprint Carbohydrate supplementation improves time-trial cycle performance during energy deficit at 4,300-m altitude
    C S Fulco
    Thermal and Mountain Medicine Division, USARIEM, Natick, MA 01760 5007, USA
    J Appl Physiol 99:867-76. 2005
  3. doi request reprint Effect of repeated normobaric hypoxia exposures during sleep on acute mountain sickness, exercise performance, and sleep during exposure to terrestrial altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA 01760, USA
    Am J Physiol Regul Integr Comp Physiol 300:R428-36. 2011
  4. ncbi request reprint Exercise performance of sea-level residents at 4300 m after 6 days at 2200 m
    Charles S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 80:955-61. 2009
  5. ncbi request reprint Carbohydrate supplementation and endurance performance of moderate altitude residents at 4300 m
    C S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Int J Sports Med 28:437-43. 2007
  6. ncbi request reprint Effect of acetazolamide on leg endurance exercise at sea level and simulated altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine USARIEM, Kansas Street, Natick, MA 01760 5007, USA
    Clin Sci (Lond) 110:683-92. 2006
  7. ncbi request reprint Gender alters impact of hypobaric hypoxia on adductor pollicis muscle performance
    C S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 91:100-8. 2001
  8. ncbi request reprint Exercise VE and physical performance at altitude are not affected by menstrual cycle phase
    B A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 86:1519-26. 1999
  9. ncbi request reprint Exercise responses after altitude acclimatization are retained during reintroduction to altitude
    B A Beidleman
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 07160, USA
    Med Sci Sports Exerc 29:1588-95. 1997
  10. ncbi request reprint Energy intake deficit and physical performance at altitude
    C S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 73:758-65. 2002

Detail Information

Publications38

  1. doi request reprint Effectiveness of preacclimatization strategies for high-altitude exposure
    Charles S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Exerc Sport Sci Rev 41:55-63. 2013
    ..Strategies using hypobaric chambers or true altitude were much more effective overall than those using normobaric hypoxia (breathing, <20.9% oxygen)...
  2. ncbi request reprint Carbohydrate supplementation improves time-trial cycle performance during energy deficit at 4,300-m altitude
    C S Fulco
    Thermal and Mountain Medicine Division, USARIEM, Natick, MA 01760 5007, USA
    J Appl Physiol 99:867-76. 2005
    ..76; P < or = 0.03). It was concluded that, despite hypoxemia exacerbated by exercise, CHOS greatly improved TT performance at ALT in which there was a negative energy balance...
  3. doi request reprint Effect of repeated normobaric hypoxia exposures during sleep on acute mountain sickness, exercise performance, and sleep during exposure to terrestrial altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA 01760, USA
    Am J Physiol Regul Integr Comp Physiol 300:R428-36. 2011
    ..Under HH conditions, the higher sleep Sa(O(2)) may have contributed to a lessening of AMS upon awakening but had no impact on AMS or exercise performance for the remainder of each day...
  4. ncbi request reprint Exercise performance of sea-level residents at 4300 m after 6 days at 2200 m
    Charles S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 80:955-61. 2009
    ..g., 4300 m). Whether staging also benefits endurance performance has not yet been scientifically evaluated...
  5. ncbi request reprint Carbohydrate supplementation and endurance performance of moderate altitude residents at 4300 m
    C S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Int J Sports Med 28:437-43. 2007
    ..However, the decrements in TT performance and exercise intensity were attenuated at 4300 m in MAR compared to those of SLR as a result of acclimatization attained while living for nearly 2 years at approximately 2000 m...
  6. ncbi request reprint Effect of acetazolamide on leg endurance exercise at sea level and simulated altitude
    Charles S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine USARIEM, Kansas Street, Natick, MA 01760 5007, USA
    Clin Sci (Lond) 110:683-92. 2006
    ..g. ventilatory induced increase in SaO2 for acetazolamide compared with placebo (89+/-1 compared with 86+/-1% respectively; P<0.05), which resulted in an increased oxygen pressure gradient from capillary to exercising muscle...
  7. ncbi request reprint Gender alters impact of hypobaric hypoxia on adductor pollicis muscle performance
    C S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 91:100-8. 2001
    ....
  8. ncbi request reprint Exercise VE and physical performance at altitude are not affected by menstrual cycle phase
    B A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 86:1519-26. 1999
    ..Moreover, neither maximal nor submaximal exercise performance is affected by menstrual cycle phase at SL or AA...
  9. ncbi request reprint Exercise responses after altitude acclimatization are retained during reintroduction to altitude
    B A Beidleman
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 07160, USA
    Med Sci Sports Exerc 29:1588-95. 1997
    ....
  10. ncbi request reprint Energy intake deficit and physical performance at altitude
    C S Fulco
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 73:758-65. 2002
    ..Physical performance of sea-level (SL) residents acutely exposed to altitude (ALT) is diminished and may improve somewhat with ALT acclimatization...
  11. ncbi request reprint Intraocular pressure and acclimatization to 4300 M altitude
    A Cymerman
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 71:1045-50. 2000
    ..Studies were conducted to determine the effect of altitude exposure on intraocular pressure (IOP) and any relationship with the severity of acute mountain sickness (AMS)...
  12. ncbi request reprint Reproducible voluntary muscle performance during constant work rate dynamic leg exercise
    C S Fulco
    U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    Int J Sports Med 21:102-6. 2000
    ..Low variability of each performance index enhanced the ability to describe the effects of acute altitude exposure on voluntary muscle function...
  13. ncbi request reprint Women at altitude: ventilatory acclimatization at 4,300 m
    S R Muza
    United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    J Appl Physiol 91:1791-9. 2001
    ....
  14. doi request reprint Intermittent hypoxic exposure does not improve sleep at 4300 m
    Juli E Jones
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 9:281-7. 2008
    ..Rather, it is likely that the acquired ventilatory acclimatization was lost in the 60 h between the last IHE session and the POST-T altitude exposure...
  15. ncbi request reprint Circulatory responses to orthostasis during alpha1-adrenergic receptor blockade at high altitude
    C S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Aviat Space Environ Med 72:1075-80. 2001
    ..g., blood pressure). We hypothesized that blocking alpha1-adrenergic receptors would impair circulatory compensation for an orthostatic challenge to a greater extent at altitude than at sea level...
  16. ncbi request reprint Improving athletic performance: is altitude residence or altitude training helpful?
    C S Fulco
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 71:162-71. 2000
    ..g., at 1250 m) to allow maintenance of high-intensity training is accumulating scientific and popular support as the most advantageous strategy to improve subsequent sea level exercise performance in well-trained, competitive runners...
  17. ncbi request reprint Postural instability and acute mountain sickness during exposure to 24 hours of simulated altitude (4300 m)
    A Cymerman
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    High Alt Med Biol 2:509-14. 2001
    ..These results indicate that postural stability is adversely affected during a 24-h exposure to 4300 m; however, there does not appear to be a correlation with the incidence or severity of AMS...
  18. ncbi request reprint Validation of a shortened electronic version of the environmental symptoms questionnaire
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 8:192-9. 2007
    ..90; p = 0.01), PP48 (k = 0.91; p = 0.01), and PP72 (k = 0.92; p = 0.01) were significant. Our findings suggest that the shortened electronic version can be substituted for the paper and pencil version of the ESQ to assess AMS...
  19. ncbi request reprint Seven intermittent exposures to altitude improves exercise performance at 4300 m
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 40:141-8. 2008
    ....
  20. doi request reprint Altitude preexposure recommendations for inducing acclimatization
    Stephen R Muza
    U S Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    High Alt Med Biol 11:87-92. 2010
    ..The subsequent ascent to high altitude should be scheduled as soon as possible after the last altitude preexposure...
  21. doi request reprint Effect of hypohydration and altitude exposure on aerobic exercise performance and acute mountain sickness
    John W Castellani
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, 42 Kansas St, Natick, MA 01760 5007, USA
    J Appl Physiol 109:1792-800. 2010
    ..07). In conclusion, hypohydration at 3,048 m 1) degrades aerobic performance in an additive manner with that induced by ALT; and 2) did not appear to increase the prevalence/severity of AMS symptoms...
  22. doi request reprint Intermittent hypoxic exposure does not improve endurance performance at altitude
    Beth A Beidleman
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 41:1317-25. 2009
    ..This study examined the effect of 1 wk of normobaric intermittent hypoxic exposure (IHE) combined with exercise training on endurance performance at a 4300-m altitude (HA)...
  23. doi request reprint Effect of six days of staging on physiologic adjustments and acute mountain sickness during ascent to 4300 meters
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    High Alt Med Biol 10:253-60. 2009
    ..56) to postSTG (45 +/- 53%; 0.59 +/- 0.43), respectively. These results suggest that modest physiologic adjustments induced by staging for 6 d at 2200 m reduced the incidence and severity of AMS during rapid, high-risk ascent to 4300 m...
  24. ncbi request reprint Substrate oxidation is altered in women during exercise upon acute altitude exposure
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 34:430-7. 2002
    ..The purpose of this study was to determine whether substrate oxidation during submaximal exercise in women is affected by an acute exposure to 4300-m altitude and menstrual cycle phase...
  25. ncbi request reprint Voluntary muscle function after creatine supplementation in acute hypobaric hypoxia
    Carol J Baker-Fulco
    Military Nutrition Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 38:1418-24. 2006
    ..To determine whether creatine (Cr) supplementation improves muscle performance during exposure to acute hypobaric hypoxia...
  26. ncbi request reprint Saccadic velocity and pupillary reflexes during acclimatization to altitude (4300 m)
    Allen Cymerman
    U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 76:627-34. 2005
    ....
  27. ncbi request reprint White blood cell and hormonal responses to 4300 m altitude before and after intermittent altitude exposure
    Beth A Beidleman
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Clin Sci (Lond) 111:163-9. 2006
    ..This method of pre-acclimatization can therefore be highly recommended for inducing altitude acclimatization without the 'altitude residency' requirement...
  28. ncbi request reprint Intermittent altitude exposures improve muscular performance at 4,300 m
    Beth A Beidleman
    Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 95:1824-32. 2003
    ..IAE may therefore be used as an alternative to chronic altitude residence to facilitate improvements in muscular performance in athletes, soldiers, mountaineers, shift workers, and others that are deployed to altitude...
  29. ncbi request reprint Incidence of adverse reactions from 23,000 exposures to simulated terrestrial altitudes up to 8900 m
    David W DeGroot
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 74:994-7. 2003
    ..The purpose of this study was to determine the rate of adverse reactions in a chamber used exclusively for terrestrial altitude research studies...
  30. ncbi request reprint Intermittent altitude exposures reduce acute mountain sickness at 4300 m
    Beth A Beidleman
    Biophysics and Biomedical Modeling Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Clin Sci (Lond) 106:321-8. 2004
    ..In conclusion, our findings suggest that 3 weeks of IAE provide an effective alternative to chronic altitude residence for increasing resting ventilation and reducing the incidence and severity of AMS...
  31. ncbi request reprint Ventilation after supplemental oxygen administration at high altitude
    Stephen R Muza
    US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Wilderness Environ Med 15:18-24. 2004
    ..The present study assessed the effects of acute hyperoxia on resting-minute ventilation (VE) during altitude acclimatization to 4300 m...
  32. ncbi request reprint Cysteinyl leukotriene blockade does not prevent acute mountain sickness
    Stephen R Muza
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 75:413-9. 2004
    ..AMS may be a manifestation of hypoxia-induced cerebral edema resulting, in part, from increased capillary permeability...
  33. ncbi request reprint Antioxidant supplementation does not attenuate oxidative stress at high altitude
    Andrew W Subudhi
    VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304 1290, USA
    Aviat Space Environ Med 75:881-8. 2004
    ..Hypobaric hypoxia and heightened metabolic rate increase free radical production...
  34. ncbi request reprint Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction
    Kimberly E Barnholt
    Clinical Studies Unit, VA Palo Alto Health Care System, 3801 Miranda Ave, Palo Alto, CA 94304, USA
    Am J Physiol Endocrinol Metab 290:E1078-88. 2006
    ..Such suppression results in the preservation of energy stores but may sacrifice the facilitation of oxygen delivery and the use of oxygen-efficient fuels...
  35. ncbi request reprint Cerebrovascular responses to incremental exercise during hypobaric hypoxia: effect of oxygenation on maximal performance
    Andrew W Subudhi
    Department of Biology, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA
    Am J Physiol Heart Circ Physiol 294:H164-71. 2008
    ..Thus cerebral hypoxia appeared to impose a limit to maximal exercise during hypobaric hypoxia (Pi(O(2)) 86 Torr), since its reversal was associated with improved performance...
  36. ncbi request reprint Cytokine responses at high altitude: effects of exercise and antioxidants at 4300 m
    Todd A Hagobian
    Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304 1290, USA
    Med Sci Sports Exerc 38:276-85. 2006
    ....
  37. ncbi request reprint Changes in ventilatory threshold at high altitude: effect of antioxidants
    Andrew W Subudhi
    Department of Biology, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA
    Med Sci Sports Exerc 38:1425-31. 2006
    ..To investigate the effects of prolonged hypoxia and antioxidant supplementation on ventilatory threshold (VT) during high-altitude (HA) exposure (4300 m)...
  38. ncbi request reprint Three weeks of caloric restriction alters protein metabolism in normal-weight, young men
    Anne L Friedlander
    Geriatric Research Education and Clinical Center and Research and Medical Services, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Am J Physiol Endocrinol Metab 289:E446-55. 2005
    ..However, despite negative nitrogen balance and loss of lean mass, whole body exercise performance was well maintained in response to CR...