J W Castellani

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi Cold strain index applied to exercising men in cold-wet conditions
    J W Castellani
    United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1764-8. 2001
  2. ncbi Cold exposure: human immune responses and intracellular cytokine expression
    John W Castellani
    USARIEM, Thermal and Mountain Medicine Division, 42 Kansas Street, Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 34:2013-20. 2002
  3. ncbi Symposium: Immune function in environmental extremes--an introduction
    John W Castellani
    USARIEM, Thermal and Mountain Medicine Division, Natick, MA 01760-5007, USA
    Med Sci Sports Exerc 34:2002-3. 2002
  4. ncbi Body fluid regulation in a simulated disabled submarine: effects of cold, reduced O2, and elevated CO2
    John W Castellani
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, 42 Kansas St, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 76:753-9. 2005
  5. ncbi Pituitary-adrenal and pituitary-thyroid hormone responses during exercise-cold exposure after 7 days of exhaustive exercise
    John W Castellani
    US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 73:544-50. 2002
  6. ncbi Cortisol and testosterone concentrations in wheelchair athletes during submaximal wheelchair ergometry
    J W Castellani
    US Army Research Institute of Environmental Medicine, 42 Kansas Street, Natick, MA 01760 5007, USA
    Eur J Appl Physiol 84:42-7. 2001
  7. ncbi Thermoregulation during cold exposure after several days of exhaustive exercise
    J W Castellani
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 90:939-46. 2001
  8. ncbi Thermoregulation during cold exposure: effects of prior exercise
    J W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 87:247-52. 1999
  9. ncbi Thermoregulatory responses to cold water at different times of day
    J W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 87:243-6. 1999
  10. ncbi Eighty-four hours of sustained operations alter thermoregulation during cold exposure
    John W Castellani
    US Army Research Institute of Environmental Medicine Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 35:175-81. 2003

Detail Information

Publications37

  1. ncbi Cold strain index applied to exercising men in cold-wet conditions
    J W Castellani
    United States Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1764-8. 2001
    ....
  2. ncbi Cold exposure: human immune responses and intracellular cytokine expression
    John W Castellani
    USARIEM, Thermal and Mountain Medicine Division, 42 Kansas Street, Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 34:2013-20. 2002
    ..Based on the review of the literature, there is no support for the concept that cold exposure depresses immune function...
  3. ncbi Symposium: Immune function in environmental extremes--an introduction
    John W Castellani
    USARIEM, Thermal and Mountain Medicine Division, Natick, MA 01760-5007, USA
    Med Sci Sports Exerc 34:2002-3. 2002
  4. ncbi Body fluid regulation in a simulated disabled submarine: effects of cold, reduced O2, and elevated CO2
    John W Castellani
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, 42 Kansas St, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 76:753-9. 2005
    ..We hypothesized that elevated CO2 levels would lead to hormone changes that would mitigate cold and hypoxia-induced body fluid losses...
  5. ncbi Pituitary-adrenal and pituitary-thyroid hormone responses during exercise-cold exposure after 7 days of exhaustive exercise
    John W Castellani
    US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 73:544-50. 2002
    ..The effects of exertional fatigue on pituitary-adrenal hormones and thyroid hormone responses to exercise-cold stress are unknown...
  6. ncbi Cortisol and testosterone concentrations in wheelchair athletes during submaximal wheelchair ergometry
    J W Castellani
    US Army Research Institute of Environmental Medicine, 42 Kansas Street, Natick, MA 01760 5007, USA
    Eur J Appl Physiol 84:42-7. 2001
    ..The greater exercise response in WA for plasma testosterone should be confirmed on a larger population. It could have been the result of the lower plasma testosterone concentrations at rest in our group...
  7. ncbi Thermoregulation during cold exposure after several days of exhaustive exercise
    J W Castellani
    Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 90:939-46. 2001
    ..These findings suggest that susceptibility to hypothermia is increased by exertional fatigue...
  8. ncbi Thermoregulation during cold exposure: effects of prior exercise
    J W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 87:247-52. 1999
    ..The combination of exercise intensity and duration studied in these experiments did not fatigue the shivering response to cold exposure...
  9. ncbi Thermoregulatory responses to cold water at different times of day
    J W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 87:243-6. 1999
    ..These data indicate that shivering and vasoconstriction are not affected by time of day. These observations raise the possibility that CWI may increase the risk of hypothermia in the early morning because of a lower initial T(core)...
  10. ncbi Eighty-four hours of sustained operations alter thermoregulation during cold exposure
    John W Castellani
    US Army Research Institute of Environmental Medicine Natick, MA 01760 5007, USA
    Med Sci Sports Exerc 35:175-81. 2003
    ..PURPOSE; This study examined the effects of short-term (3.5 d) sustained military operations (SUSOPS) on thermoregulatory responses to cold stress...
  11. ncbi Exertional fatigue, sleep loss, and negative energy balance increase susceptibility to hypothermia
    A J Young
    United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 85:1210-7. 1998
    ..A short period of rest, sleep, and refeeding restored the thermogenic response to cold, but thermal balance in the cold remained compromised until after several weeks of recovery when tissue insulation had been restored...
  12. ncbi Physiological responses to cold exposure in men: a disabled submarine study
    J W Castellani
    US Army Research Institute of Environmental Medicine, Natick, MA 01760-5007, USA
    Undersea Hyperb Med 29:189-203. 2002
    ..These thermoregulatory effector changes do not increase the risk for hypothermia in DISSUB survivors who are adequately clothed...
  13. ncbi Human thermoregulatory responses during serial cold-water immersions
    J W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760 5007, USA
    J Appl Physiol 85:204-9. 1998
    ..An alternative explanation is that shivering habituation develops rapidly during serially repeated cold exposures...
  14. ncbi Rehydration with fluid of varying tonicities: effects on fluid regulatory hormones and exercise performance in the heat
    R W Kenefick
    US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Natick, MA 01760, USA
    J Appl Physiol 102:1899-905. 2007
    ..Neither a fluid of greater tonicity nor the route of administration resulted in a more rapid or greater fluid retention, nor did it enhance heat tolerance or diminish physiological strain during subsequent exercise in the heat...
  15. ncbi Telemetry pill measurement of core temperature in humans during active heating and cooling
    C O'BRIEN
    U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 30:468-72. 1998
    ....
  16. ncbi Effect of increased plasma osmolality on cold-induced thirst attenuation
    Robert William Kenefick
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Kansas Street, Natick, MA, 01760, USA
    Eur J Appl Physiol 104:1013-9. 2008
    ..Thirst ratings remained elevated (P < 0.05) in the DH + NaCl treatment 30 min after dosing and 45 min at 4 degrees C versus DH + P and EU + P. Attenuation of thirst when dehydrated in the cold can be over-ridden by increasing P (osm)...
  17. ncbi Exertion-induced fatigue and thermoregulation in the cold
    A J Young
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Comp Biochem Physiol A Mol Integr Physiol 128:769-76. 2001
    ....
  18. ncbi Epidemiology of U.S. Army cold weather injuries, 1980-1999
    David W DeGroot
    U S Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 74:564-70. 2003
    ..The purpose of this cross-sectional study was to determine the occurrence of CWI hospitalizations in the U.S. Army from 1980 to 1999, and to identify possible trends, high-risk groups and/or activities...
  19. ncbi Rapid IV versus oral rehydration: responses to subsequent exercise heat stress
    Robert W Kenefick
    U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 38:2125-31. 2006
    ..This study sought to determine the effect of rapid intravenous (IV) versus oral (ORAL) rehydration immediately after dehydration, on cardiovascular, thermoregulatory, and perceptual responses during subsequent exercise in the heat...
  20. ncbi Thermal responses for men with different fat compositions during immersion in cold water at two depths: prediction versus observation
    Xiaojiang Xu
    Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA, 01760, USA
    Eur J Appl Physiol 100:79-88. 2007
    ..CTM predicts Tc responses to immersion at various depths with acceptable accuracy for NF individuals in this study and can be adapted to non-uniform environments...
  21. ncbi How hot is the human body?
    Michael N Sawka
    J Appl Physiol 103:419-20. 2007
  22. ncbi Cognitive, psychomotor, and physical performance in cold air after cooling by exercise in cold water
    Catherine O'Brien
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Kansas Street, Building 42, Natick, MA 01760 5007, USA
    Aviat Space Environ Med 78:568-73. 2007
    ..This study evaluated performance after lowering core temperature at different rates while local tissues were either cooled (lower body) or not cooled (upper body)...
  23. ncbi Exertional fatigue and cold exposure: mechanisms of hiker's hypothermia
    Andrew J Young
    US Army Research Institute of Environmental Medicine, Kansas St, Natick, MA 01760 5007, USA
    Appl Physiol Nutr Metab 32:793-8. 2007
    ..The mechanisms accounting for this thermoregulatory impairment are not clear, but the possibility that changes in blood glucose availability or sympathetic responsiveness to cold due to exertion and fatigue merit further research...
  24. ncbi Evaluation of two cold thermoregulatory models for prediction of core temperature during exercise in cold water
    John W Castellani
    Thermal and Mountain Medicine Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    J Appl Physiol 103:2034-41. 2007
    ..Algorithms need to be developed to better predict heat loss during exercise in cold water...
  25. ncbi Hydration effects on cognitive performance during military tasks in temperate and cold environments
    Gina E Adam
    U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Physiol Behav 93:748-56. 2008
    ..Moderate HYP had no effect on cognitive and psychomotor performance in either environment, cold exposure produced equivocal effects, and aerobic exercise improved some aspects of military task performance...
  26. ncbi American College of Sports Medicine position stand: prevention of cold injuries during exercise
    John W Castellani
    Med Sci Sports Exerc 38:2012-29. 2006
    ....
  27. ncbi Dietary tyrosine benefits cognitive and psychomotor performance during body cooling
    Caroline Mahoney
    Thermal and Mountain Medicine Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Physiol Behav 90:301-7. 2007
    ....
  28. ncbi Cognition during sustained operations: comparison of a laboratory simulation to field studies
    Harris R Lieberman
    U S Army Research Institute of Environmental Medicine, Natick 01760 5007, USA
    Aviat Space Environ Med 77:929-35. 2006
    ..Our laboratory developed a brief, intense, laboratory-based simulation of a multistressor environment which included sleep loss, continuous physical activity, and food deprivation...
  29. ncbi Differential responses of IGF-I molecular complexes to military operational field training
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Appl Physiol 95:1083-9. 2003
    ..the relative proportion of IGF-I sequestered in ternary vs. nonternary molecular complexes appears to be well maintained...
  30. ncbi Reliability assessment of two militarily relevant occupational physical performance tests
    Clay E Pandorf
    Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA, USA
    Can J Appl Physiol 28:27-37. 2003
    ..This study demonstrates that both are reliable tests, but they do require administration of 1 single-trial session of RBLT and 2 two-trial sessions of OC before highly reliable performance data are obtained...
  31. ncbi Thirst sensations and AVP responses at rest and during exercise-cold exposure
    Robert W Kenefick
    Department of Kinesiology, The University of New Hampshire, Durham, NH 03824, USA
    Med Sci Sports Exerc 36:1528-34. 2004
    ..The purpose of this study was to 1) determine the effect of hypohydration (HYPO) on thirst sensations during moderate exercise in the cold and 2) determine a possible mechanism for a cold-induced decline in thirst...
  32. ncbi Reliability assessment of ballistic jump squats and bench throws
    Joseph A Alemany
    Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    J Strength Cond Res 19:33-8. 2005
    ..Slightly greater variability for JS was observed, although the test had high reliability...
  33. ncbi Hypohydration impairs endurance exercise performance in temperate but not cold air
    Samuel N Cheuvront
    US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Kansas St, Natick, MA 01760 5007, USA
    J Appl Physiol 99:1972-6. 2005
    ..05). These data demonstrate that 1) HYP impairs endurance exercise performance in temperate but not cold air but 2) cold stress per se does not...
  34. ncbi Physical performance responses during 72 h of military operational stress
    Bradley C Nindl
    Military Performance Division, U S Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 34:1814-22. 2002
    ..To characterize the impact of prolonged work, underfeeding, and sleep deprivation (i.e., sustained operations; SUSOPS) on physical and occupational related performance during military operational stress...
  35. ncbi Altered secretion of growth hormone and luteinizing hormone after 84 h of sustained physical exertion superimposed on caloric and sleep restriction
    Bradley C Nindl
    Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760, USA
    J Appl Physiol 100:120-8. 2006
    ..During periods of energy deficiency, amplitude modulation of GH and LH pulses may precede alterations in pulse numbers...
  36. ncbi Energy expenditure in men and women during 54 h of exercise and caloric deprivation
    John W Castellani
    US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA
    Med Sci Sports Exerc 38:894-900. 2006
    ..Men and women completed the same physical tasks...
  37. ncbi Hypohydration effects on thermoregulation during moderate exercise in the cold
    Robert W Kenefick
    Department of Kinesiology, The University of New Hampshire, New Hampshire Hall, NH 03824, Durham, USA
    Eur J Appl Physiol 92:565-70. 2004
    ..These data demonstrate that moderate intensity exercise in the cold while hypohydrated does not alter metabolic heat production, skin temperatures and heat loss, nor does it increase thermoregulatory and cardiovascular strain...