Research Topics
| Kent WallnerSummaryCountry: USA Publications
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Publications
125I versus 103Pd for low-risk prostate cancer: preliminary PSA outcomes from a prospective randomized multicenter trialKent Wallner
Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA 98108, USA
Int J Radiat Oncol Biol Phys 57:1297-303. 2003..To compare prostate cancer control rates in patients who received (125)I vs. (103)Pd...
I-125 versus Pd-103 for low-risk prostate cancer: long-term morbidity outcomes from a prospective randomized multicenter controlled trialAndrew Herstein
Department of Radiation Oncology, Seattle, Washington, USA
Cancer J 11:385-9. 2005..The trend toward more proctitis in the I-125 patient group likely reflects their higher R100 values due to less rapid dose fall-off that can be overcome with judicious treatment planning and implant execution...
20 Gy versus 44 Gy supplemental beam radiation with Pd-103 prostate brachytherapy: preliminary biochemical outcomes from a prospective randomized multi-center trialKent Wallner
Department of Veterans Affairs, Radiation Oncology, Puget Sound Health Care System, Seattle, WA 98108 1597, USA
Radiother Oncol 75:307-10. 2005..Similar to classic randomized Wilm's tumor studies from the 1980s, the intention of the trial design was to decrementally test the need for beam radiation...
There is a wide range of predictive dosimetric factors for I-125 and pd-103 prostate brachytherapyAndrew Herstein
Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, Washington, USA
Am J Clin Oncol 31:6-10. 2008..We have analyzed biochemical control versus multiple dosimetric parameters for a relatively homogeneous group of low-risk patients treated with I-125 or Pd-103...
Morbidity effect of the time gap between supplemental beam radiation and Pd-103 prostate brachytherapyJacques Corriveau
Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA, USA
Brachytherapy 2:108-13. 2003..There was no relationship between beam doses and RTOG rectal morbidity scores. CONCLUSIONS: The findings reported here are suggestive that short gap times are safe...
The time gap between Pd-103 prostate brachytherapy and supplemental beam radiation does not impact on rectal morbidity or likelihood of cureNathan Bittner
Department of Radiation Oncology, University of Washington, Seattle, WA 98195 6043, USA
Am J Clin Oncol 31:231-6. 2008..To determine whether treatment gap between supplemental beam radiation and brachytherapy implant affects rectal morbidity and likelihood of cure in the treatment of intermediate-risk prostate cancer...
Perirectal seeds as a risk factor for prostate brachytherapy-related rectal bleedingAmy Mueller
Radiation Oncology (#174, Veterans Affairs Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA 98108-1597, USA
Int J Radiat Oncol Biol Phys 59:1047-52. 2004..025). CONCLUSION: A limited number of errant perirectal sources in itself does not appear to place patients at increased risk of rectal bleeding, providing that the overall rectal wall doses are within acceptable values...
Factors predictive of rectal bleeding after 103Pd and supplemental beam radiation for prostate cancerTracy Sherertz
Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, 1600 S. Columbian Way, Seattle, WA 98108-1597, USA
Brachytherapy 3:130-5. 2004....
Rectal fistulas after prostate brachytherapyAudrey Tran
Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA
Int J Radiat Oncol Biol Phys 63:150-4. 2005..High rectal radiation doses should be avoided a priori, to minimize the likelihood of rectal bleeding, and hence the likelihood that invasive procedures will be performed...
Dosimetric parameters as predictive factors for biochemical control in patients with higher risk prostate cancer treated with Pd-103 and supplemental beam radiationPeter Orio
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Int J Radiat Oncol Biol Phys 67:342-6. 2007..To analyze the role of dosimetric quality parameters in maximizing cancer eradication in higher risk prostate cancer patients treated with palladium (Pd)-103 and supplemental beam radiation...
The effect of supplemental beam radiation on prostate brachytherapy-related morbidity: morbidity outcomes from two prospective randomized multicenter trialsMaged Ghaly
Department of Radiation Oncology, Methodist Hospital, New York, NY, USA
Int J Radiat Oncol Biol Phys 55:1288-93. 2003..CONCLUSION: The addition of supplemental beam radiation had little effect on morbidity. We do not believe that morbidity per se should influence the decision of whether or not to use supplemental beam radiation...
Prostatic acid phosphatase adversely affects cause-specific survival in patients with intermediate to high-risk prostate cancer treated with brachytherapyL Christine Fang
Department of Radiation Oncology, University of Washington Medical Center, Seattle, Washington 98195, USA
Urology 71:146-50. 2008....
High-dose regions versus likelihood of cure after prostate brachytherapyKent Wallner
Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA 98108 1597, USA
Int J Radiat Oncol Biol Phys 62:170-4. 2005..To analyze the effect of high-dose regions on biochemical cancer control rates after prostate brachytherapy...
The prognostic significance of Gleason pattern 5 in prostate cancer patients treated with Pd 103 plus beam radiation therapyTracy Sherertz
Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, Washington 98108, USA
Cancer J 10:301-6. 2004....
The prognostic significance of Gleason pattern 5 in prostate cancer patients treated with Pd-103 brachytherapyHiroki Mitsuyama
Department of Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA 98108 1597, USA
Am J Clin Oncol 30:597-600. 2007..To determine the effect of high-grade prostate cancer (Gleason pattern 5) on the prognosis of patients treated with Pd-103 brachytherapy...
Effect of post-implant edema on prostate brachytherapy treatment marginsDaniel R Reed
Radiation Oncology, Arizona Oncology Services, Phoenix, AZ 85260, USA
Int J Radiat Oncol Biol Phys 63:1469-73. 2005..9 mm on Day 0 to 4.7 mm on Day 30. CONCLUSION: Treatment margins appear to be durable in the postimplant period, with a clinically insignificant increase from Day 0 to Day 30...
Optimized prostate brachytherapy minimizes the prognostic impact of percent of biopsy cores involved with adenocarcinomaRizwan Nurani
Department of Radiation Oncology, Puget Sound Health Care System, Seattle, Washington 98108 1597, USA
J Urol 178:1968-73; discussion 1973. 2007....
Clinical correlates of high intraprostatic brachytherapy dose volumesShaleah Jones
Medical School, University of Washington, Seattle, USA
Int J Radiat Oncol Biol Phys 53:328-33. 2002..CONCLUSION: Expending substantial effort to monitor and modify higher-dose volumes, at least in the setting of modified peripheral loading patterns, is unlikely to substantially decrease implant-related morbidity...
Seed-based transrectal ultrasound-fluoroscopy registration method for intraoperative dosimetry analysis of prostate brachytherapyIsmail B Tutar
Department of Electrical Engineering, Image Computing Systems Laboratory, University of Washington, Seattle, Washington 98195, USA
Med Phys 35:840-8. 2008..2 cm even when the seed detection rate is only 10%. We believe that IOA can offer a robust solution to seed-based TRUS-fluoroscopy registration, thus making intraoperative dosimetry possible...
The effect of interobserver differences in post-implant prostate CT image interpretation on dosimetric parametersBen H Han
Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
Med Phys 30:1096-102. 2003..The V100 and TMs are less influenced by interobserver CT interpretation variability than is the D90, and may be better suited as interinstitutional quality indices...
Epididymitis after prostate brachytherapyS Christopher Hoffelt
Department of Radiation Oncology, Oregon Health and Sciences University, Portland, Oregon, USA
Urology 63:293-6. 2004..That epididymitis patients had greater preimplant AUA scores is consistent with a retrograde infection route, at least in some cases...
Clinical correlates to PSA spikes and positive repeat biopsies after prostate brachytherapyDaniel Reed
Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington, USA
Urology 62:683-8. 2003..On the basis of the patient data reported here, it appears that a spike up to 10 ng/mL is still consistent with cancer eradication...
Modification of prostate implants based on postimplant treatment margin assessmentAmy Mueller
Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
Med Phys 29:2782-7. 2002..It seems that doing so, even in experienced hands, will require a reappraisal of our implant techniques, or the addition of intraoperative dosimetric analysis with the capacity to substantially modify the implant with extra sources...
Semiautomatic 3-D prostate segmentation from TRUS images using spherical harmonicsIsmail B Tutar
Image Computing Systems Laboratory, Departments of Electrical Engineering and Bioengineering, University of Washington, Seattle, WA 98195, USA
IEEE Trans Med Imaging 25:1645-54. 2006..The overall mean absolute distance error was 1.26 +/- 0.41 mm while the percent volume overlap was 83.5 +/- 4.2. We found the segmentation error to be slightly less than the clinically-observed interobserver variability...
Reviving the acid phosphatase test for prostate cancerAl Taira
Department of Radiation Oncology, University of Washington, Seattle, Washington 98195, USA
Oncology (Williston Park) 21:1003-10. 2007....
Prostate brachytherapy under local anesthesia; lessons from the first 600 patientsKent Wallner
Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA, USA
Brachytherapy 1:145-8. 2002..Local anesthesia for prostate brachytherapy was instituted at the Puget Sound Veterans Hospital in 1999, peforming the procedure in our own department without anesthesia personnel in attendance...
I-125 versus Pd-103 for low-risk prostate cancer: morbidity outcomes from a prospective randomized multicenter trialKent Wallner
Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, Washington 98108-1597, USA
Cancer J 8:67-73. 2002....
A reappraisal of local anesthesia for prostate brachytherapyAmy Mueller
Radiation Oncology, Puget Sound Health Care System, Department of Veterans Affairs, Seattle, WA 98108-1597, USA
Radiother Oncol 67:309-12. 2003..CONCLUSIONS: Performing prostate brachytherapy under local anesthesia, as reported here, is simple, efficient and well tolerated...
Gross hematuria after prostate brachytherapyJerry Barker
Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington, USA
Urology 61:408-11. 2003..Such an analysis will require a more controlled, prospective study of a large implant patient population...
Prostate brachytherapy in obese patientsJason Rockhill
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Brachytherapy 1:54-60. 2002..For the 2 sub-350-pound patients who could be imaged on our CT scanner, postimplant target coverage (V100) was 88% and 95%. CONCLUSIONS: Standard TRUS and brachytherapy needles are sufficient to implant even the largest patients...
Medical malpractice of prostate brachytherapyKathryn Elliott
School of Law, University of Washington, Seattle, WA, USA
Brachytherapy 3:231-6. 2004..CONCLUSION: Prostate brachytherapists should brace themselves for the likelihood of more lawsuits. In addition to fistulas, plaintiff attorneys are likely to devise more bases for lawsuits in the future...
Late urinary function after prostate brachytherapyDaniel Landis
Department of Radiation Oncology, University of Washington, Seattle, WA, USA
Brachytherapy 1:21-6. 2002....
Chronic pelvic pain following prostate brachytherapy: a case reportKent Wallner
Radiation Oncology 174, Department of Veterans Affairs, 1660 S Columbian Way, Seattle, WA 98108 1597, USA
Brachytherapy 3:153-8. 2004..To alert physicians and potential patients that chronic postimplant pelvic pain syndromes can occur, and that dosimetric parameters (i.e., implant technique) may predispose patients to it...
Urinary morbidity in brachytherapy patients with median lobe hyperplasiaJohnathan Nguyen
School of Medicine, University of Washington, Seattle, WA, USA
Brachytherapy 1:42-7. 2002..Considering that even patients with prolonged retention have gradually improved spontaneously, we do not advocate prophylactic prebrachytherapy resection of hypertrophic tissue in MLH patients...
Permanent prostate brachytherapy-induced morbidity in patients with grade II and III obesityGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital, Wheeling, West Virginia 26003-6300, USA
Urology 60:104-8. 2002..In addition, the dosimetric quality of the implants was outstanding, and the short-term biochemical outcome was encouraging...
Risk factors for acute urinary retention requiring temporary intermittent catheterization after prostate brachytherapy: a prospective studyJacob Locke
Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63108, USA
Int J Radiat Oncol Biol Phys 52:712-9. 2002..We prospectively investigated prognostic factors for men undergoing transperineal radioactive seed implantation for prostate cancer at the University of Washington...
Extraprostatic seed placement and its effect on seed lossElena Nedea
Department of Radiation Oncology, McGill University, Montreal, Quebec, Canada
Cancer J 11:147-51. 2005..CONCLUSIONS: We have shown here that with CT and MR seed localization, extraprostatic seed placement does not appear to substantially increase the likelihood of seed loss after the procedure...
Long-term outcomes after treatment with brachytherapy and supplemental conformal radiation for prostate cancer patients having intermediate and high-risk featuresMichael Dattoli
Dattoli Cancer Center and Brachytherapy Research Institute, Sarasota, Florida, USA
Cancer 110:551-5. 2007..This study summarizes long-term outcomes from treatment of prostate cancer with increased risk of extracapsular cancer extension (ECE) using brachytherapy-based treatment...
Prostate cancer distribution in patients diagnosed by transperineal template-guided saturation biopsyGregory S Merrick
Schiffler Cancer Center, Wheeling Hospital and Wheeling Jesuit University, Wheeling, WV 26003 6300, USA
Eur Urol 52:715-23. 2007..To determine the prostate cancer incidence, anatomic distribution, Gleason score profile, and tumor burden in patients diagnosed by transperineal template-guided saturation biopsy (TTSB)...
Long-term prostate cancer control using palladium-103 brachytherapy and external beam radiotherapy in patients with a high likelihood of extracapsular cancer extensionMichael Dattoli
Dattoli Cancer Center and Brachytherapy Research Institute, Sarasota, Florida 34217, USA
Urology 69:334-7. 2007..To report the long-term biochemical control rates with brachytherapy-based treatment for patients with prostate cancer at high risk of extracapsular cancer extension...
Long-term outcomes after treatment with external beam radiation therapy and palladium 103 for patients with higher risk prostate carcinoma: influence of prostatic acid phosphataseMichael Dattoli
Dattoli Cancer Center and Brachytherapy Research Institute, Sarasota, Florida 34237, USA
Cancer 97:979-83. 2003..This report adds to the rationale for reintroducing PAP measurement into general practice...
MR imaging for prostate cancer staging: beauty or beast?Kent Wallner
Int J Radiat Oncol Biol Phys 52:886-7. 2002
American Brachytherapy Society recommendations for reporting morbidity after prostate brachytherapySubir Nag
American Brachytherapy Society, Oakbrook, IL, USA
Int J Radiat Oncol Biol Phys 54:462-70. 2002..To standardize the reporting of brachytherapy-related prostate morbidity to guide ongoing clinical practice and future investigations...
Factors affecting patient selection for prostate brachytherapy: what nurses should knowDebra Zeroski
Clin J Oncol Nurs 9:553-60. 2005..Clinical studies seek to further define patient selection criteria and examine optimal choices for adjuvant treatment and isotope preference. Expanding the knowledge base of nurses helps enhance patient care...
