R Waksman

Summary

Country: USA

Publications

  1. ncbi PhotoPoint photodynamic therapy promotes stabilization of atherosclerotic plaques and inhibits plaque progression
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 52:1024-32. 2008
  2. ncbi Bivalirudin versus unfractionated heparin in patients undergoing percutaneous coronary intervention after acute myocardial infarction
    William W Chu
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Cardiovasc Revasc Med 7:132-5. 2006
  3. ncbi FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study
    Ron Waksman
    Medstar Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 61:917-23. 2013
  4. ncbi Evolution of percutaneous balloon aortic valvuloplasty in the treatment of patients with aortic stenosis
    L K Pendyala
    Interventional Cardiology, Medstar Washington Hospital Center, Washington, DC, USA
    Minerva Med 103:415-29. 2012
  5. ncbi Percutaneous coronary intervention with second-generation paclitaxel-eluting stents versus everolimus-eluting stents in United States contemporary practice (REWARDS TLX Trial)
    Ron Waksman
    MedStar Washington Hospital Center MedStar Health Research Institute, Washington, DC, USA
    Am J Cardiol 110:1119-24. 2012
  6. ncbi In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 80:429-36. 2012
  7. ncbi Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice
    Ron Waksman
    Interventional Cardiology, Washington Hospital Center, DC, USA
    Am J Cardiol 109:1288-94. 2012
  8. ncbi Coating bioabsorption and chronic bare metal scaffolding versus fully bioabsorbable stent
    Ron Waksman
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 10 Irving Street NW, Washington, DC 20010, USA
    EuroIntervention 5:F36-42. 2009
  9. ncbi Glycoprotein IIb/IIIa inhibitors and bivalirudin in patients undergoing percutaneous coronary intervention
    M Mahmoudi
    Department of Internal Medicine, Washington Hospital Center, Washington, DC, USA
    Minerva Cardioangiol 60:95-100. 2012
  10. ncbi Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients
    Michael R Elashoff
    CardioDx, Inc, 2500 Faber Place, Palo Alto, CA 94602, USA
    BMC Med Genomics 4:26. 2011

Collaborators

Detail Information

Publications156 found, 100 shown here

  1. ncbi PhotoPoint photodynamic therapy promotes stabilization of atherosclerotic plaques and inhibits plaque progression
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 52:1024-32. 2008
    ..The purpose of this study was to determine how photodynamic therapy (PDT) promotes stabilization and reduction of regional atherosclerosis...
  2. ncbi Bivalirudin versus unfractionated heparin in patients undergoing percutaneous coronary intervention after acute myocardial infarction
    William W Chu
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Cardiovasc Revasc Med 7:132-5. 2006
    ..41). CONCLUSION: The use of bivalirudin in patients undergoing PCI after AMI is safe and feasible. Bivalirudin should be considered as an alternative anticoagulant agent during PCI to treat patients presenting with AMI...
  3. ncbi FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study
    Ron Waksman
    Medstar Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 61:917-23. 2013
    ....
  4. ncbi Evolution of percutaneous balloon aortic valvuloplasty in the treatment of patients with aortic stenosis
    L K Pendyala
    Interventional Cardiology, Medstar Washington Hospital Center, Washington, DC, USA
    Minerva Med 103:415-29. 2012
    ..BAV can be used as a selection tool to determine if the patient will benefit from valve replacement if they have other comorbidities, such as severe pulmonary hypertension, severe lung disease, very poor ejection fraction, or frailty...
  5. ncbi Percutaneous coronary intervention with second-generation paclitaxel-eluting stents versus everolimus-eluting stents in United States contemporary practice (REWARDS TLX Trial)
    Ron Waksman
    MedStar Washington Hospital Center MedStar Health Research Institute, Washington, DC, USA
    Am J Cardiol 110:1119-24. 2012
    ..However, for composite efficacy and safety end points, EESs outperformed second-generation PESs...
  6. ncbi In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 80:429-36. 2012
    ....
  7. ncbi Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice
    Ron Waksman
    Interventional Cardiology, Washington Hospital Center, DC, USA
    Am J Cardiol 109:1288-94. 2012
    ..The XIENCE V failed to demonstrate superiority for overall major adverse cardiovascular events, Q-wave myocardial infarction, and revascularization rates...
  8. ncbi Coating bioabsorption and chronic bare metal scaffolding versus fully bioabsorbable stent
    Ron Waksman
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 10 Irving Street NW, Washington, DC 20010, USA
    EuroIntervention 5:F36-42. 2009
    ..This manuscript will discuss the wide variety of new stent technologies and compare and contrast durable metallic and polymeric stents to current biodegradable stent technology...
  9. ncbi Glycoprotein IIb/IIIa inhibitors and bivalirudin in patients undergoing percutaneous coronary intervention
    M Mahmoudi
    Department of Internal Medicine, Washington Hospital Center, Washington, DC, USA
    Minerva Cardioangiol 60:95-100. 2012
    ....
  10. ncbi Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients
    Michael R Elashoff
    CardioDx, Inc, 2500 Faber Place, Palo Alto, CA 94602, USA
    BMC Med Genomics 4:26. 2011
    ..A non-invasive blood test that could reliably assess obstructive CAD likelihood would have diagnostic utility...
  11. ncbi Optimal dosing and duration of oral everolimus to inhibit in-stent neointimal growth in rabbit iliac arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Cardiovasc Revasc Med 7:179-84. 2006
    ..Everolimus is an orally active derivative of sirolimus. Oral administration of rapamycin is efficacious in the reduction of neointima formation and clinical restenosis; however, its optimal dose and duration have not been determined...
  12. ncbi Safety and efficacy of bioabsorbable magnesium alloy stents in porcine coronary arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 68:607-17; discussion 618-9. 2006
    ....
  13. ncbi Intracoronary photodynamic therapy reduces neointimal growth without suppressing re-endothelialisation in a porcine model
    R Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Heart 92:1138-44. 2006
    ..To examine the effects of intracoronary PhotoPoint photodynamic therapy (PDT) with a new photosensitiser, MV0611, in the overstretch balloon and stent porcine models of restenosis...
  14. ncbi Twelve versus six months of clopidogrel to reduce major cardiac events in patients undergoing gamma-radiation therapy for in-stent restenosis: Washington Radiation for In-Stent restenosis Trial (WRIST) 12 versus WRIST PLUS
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Circulation 106:776-8. 2002
    ..Late thrombosis was attenuated with 6 months of aspirin and clopidogrel. We aimed to find out whether 12 months of aspirin plus clopidogrel is superior to a strategy of 6 months after radiation therapy for patients with ISR...
  15. ncbi Update on bioabsorbable stents: from bench to clinical
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    J Interv Cardiol 19:414-21. 2006
    ..Bioabsorbable stents are considered the next frontier of stenting and we will discuss their potential to fulfill this promise in interventional cardiology...
  16. ncbi ACUITY-PCI: one drug does not fit all
    Ron Waksman
    Washington Hospital Center, Washington, DC 20010, USA
    Lancet 369:881-2. 2007
  17. ncbi Long-term clinical outcomes and thrombosis rates of sirolimus-eluting versus paclitaxel-eluting stents in an unselected population with coronary artery disease (REWARDS registry)
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 100:45-51. 2007
    ..In conclusion, use of SESs and PESs in unrestricted, contemporary practice had comparable outcomes in terms of low rates of revascularization and clinical events. Stent thrombosis continues to be a major concern for SESs and PESs...
  18. ncbi Efficacy and safety of absorbable metallic stents with adjunct intracoronary beta radiation in porcine coronary arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Interv Cardiol 20:367-72. 2007
    ..These stents, however, are associated with a modest degree of late recoil and intimal hyperplasia. The aim of the study was to test whether adjunct vascular brachytherapy (VBT) compared to AMS alone can overcome these limitations...
  19. ncbi Use of localised intracoronary beta radiation in treatment of in-stent restenosis: the INHIBIT randomised controlled trial
    Ron Waksman
    Cardiovascular Brachytherapy Institute, Washington Hospital Center, Washington DC 20010, USA
    Lancet 359:551-7. 2002
    ..We aimed to compare the effects of intracoronary beta radiation treatment with those of placebo for clinical and angiographic outcomes of patients with diffuse in-stent restenosis...
  20. ncbi Efficacy and safety of pimecrolimus-eluting stents in porcine coronary arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Cardiovasc Revasc Med 8:259-74. 2007
    ..We aimed to evaluate an effective dosage and safety profile of pimecrolimus as an anti-inflammatory drug for drug-eluting stents...
  21. ncbi Balloon-based radiation therapy for treatment of in-stent restenosis in human coronary arteries: results from the BRITE I study
    Ron Waksman
    Cardiovascular Brachytherapy Institute, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 57:286-94. 2002
    ..5%. Beta-radiation delivered with a balloon P-32 source design for patients with in-stent restenosis results in lower than expected rate of angiographic and clinical restenosis and the absence of late complications...
  22. ncbi Drug-eluting stents versus repeat vascular brachytherapy for patients with recurrent in-stent restenosis after failed intracoronary radiation
    William W Chu
    Washington Hospital Center, Division of Cardiology, 110 Irving Street, N W, Suite 4B 1, Washington, D C, 20010, USA
    J Invasive Cardiol 17:659-62. 2005
    ..Therefore, repeat IRT should be considered as an option for this difficult patient subset...
  23. ncbi Oral rapamycin inhibits growth of atherosclerotic plaque in apoE knock-out mice
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street, NW, Suite 4B 1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 4:34-8. 2003
    ..This study is designed to test the potential of oral rapamycin to inhibit atherosclerotic plaque development...
  24. ncbi Coronary brachytherapy in the drug-eluting stent era: don't bury it alive
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, 100 Irving St, NW, Suite 4B-1, Washington, DC 20010, USA
    Circulation 108:386-8. 2003
  25. ncbi Repeat intracoronary radiation for recurrent in-stent restenosis in patients who failed intracoronary radiation
    Ron Waksman
    Washington Hospital Center, 110 Irving St, NW, Suite 4B 1, Washington, DC 20010, USA
    Circulation 108:654-6. 2003
    ..It is, however, associated with a significant failure rate. The present study evaluated the outcomes of patients who underwent repeat intracoronary radiation for recurrent ISR...
  26. ncbi Drug-eluting stents: from bench to bed
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, 110 Irving Street, NW, Suite 4B 1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 3:226-41. 2002
    ....
  27. ncbi Beta emitter systems and results from clinical trials. state of the art
    Ron Waksman
    Washington Hospital Center, 110 Irving Street, NW, Suite 4B 1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 4:54-63. 2003
    ..This review is intended to summarize the clinical trials utilizing beta emitter systems for the treatment of ISR and de novo lesions and their subsequent results...
  28. ncbi Five-year follow-up after intracoronary gamma radiation therapy for in-stent restenosis
    Ron Waksman
    Washington Hospital Center, 110 Irving St NW, Suite 4B 1, Washington, DC 20010, USA
    Circulation 109:340-4. 2004
    ..The Washington Radiation for In-Stent Restenosis Trial is a double-blinded randomized study evaluating the effects of intracoronary radiation therapy (IRT) in patients with in-stent restenosis (ISR)...
  29. ncbi Review of intracoronary radiation for in-stent restenosis
    Robert Lew
    Cardiovascular Research Institute, Cardiology Division, Washington Hospital Center, 110 Irving Street, N.W, Suite 4B-1, Washington, D.C, 20010, USA
    J Invasive Cardiol 15:2A-8A. 2003
  30. ncbi Bone marrow and bone marrow derived mononuclear stem cells therapy for the chronically ischemic myocardium
    Ron Waksman
    Division of Cardiology, Cardiovascular Research Institute, Washington Hospital Center, 100 Irving Street, Northwest, Suite 4B 1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 4:164-8. 2003
    ..Randomized, double blind and placebo-controlled clinical trials need to be completed to determine the effectiveness of stem cell...
  31. ncbi Intracoronary radiation therapy improves the clinical and angiographic outcomes of diffuse in-stent restenotic lesions: results of the Washington Radiation for In-Stent Restenosis Trial for Long Lesions (Long WRIST) Studies
    Ron Waksman
    Washington Hospital Center, 110 Irving St, NW, Suite 4B 1, Washington, DC 20010, USA
    Circulation 107:1744-9. 2003
    ..The Washington Radiation for In-Stent Restenosis Trial for long lesions (Long WRIST) was designed to determine the safety and efficacy of vascular brachytherapy for the treatment of diffuse in-stent restenosis...
  32. ncbi Use of IIb/IIIa inhibitors in patients with in-stent restenosis treated with intracoronary gamma-radiation. Integrilin WRIST
    Ron Waksman
    Cardiology Research Institute, Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 62:162-6. 2004
    ..Major bleeding was similar in patients treated with and without eptifibatide. Overall, the use of eptifibatide as adjunct therapy for patients with ISR that are treated with IRT did not impact the clinical outcome at 30 days...
  33. ncbi Transepicardial autologous bone marrow-derived mononuclear cell therapy in a porcine model of chronically infarcted myocardium
    Ron Waksman
    Washington Hospital Center, Suite 4B 1, 110 Irving Street, NW, Washington, DC 20010, USA
    Cardiovasc Radiat Med 5:125-31. 2004
    ..We evaluated the effect of bone marrow-derived mononuclear cell (BMMNC) transplantation on collateral vessel development and myocardial function in a porcine model of chronically infarcted heart...
  34. ncbi Short-term effects of biocorrodible iron stents in porcine coronary arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Interv Cardiol 21:15-20. 2008
    ..This study aimed to test the safety and efficacy of biocorrodible iron stents in porcine coronary arteries...
  35. ncbi Effect of clopidogrel on neointimal formation and inflammation in balloon-denuded and radiated hypercholesterolemic rabbit iliac arteries
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Interv Cardiol 21:122-8. 2008
    ..The aim of this study is to find out by modulating inflammation if clopidogrel can affect neointima formation in balloon-denuded iliac arteries of hypercholesterolemic rabbits...
  36. ncbi Drug-eluting stents: is new necessarily better?
    Ron Waksman
    Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Lancet 372:1126-8. 2008
  37. ncbi Intravascular gamma radiation for in-stent restenosis in saphenous-vein bypass grafts
    Ron Waksman
    Division of Cardiology, Washington Hospital Center and the Washington Cancer Institute, Washington, DC 20010, USA
    N Engl J Med 346:1194-9. 2002
    ..We examined the effects of intravascular gamma radiation in patients with in-stent restenosis of saphenous-vein bypass grafts...
  38. ncbi Drug-eluting stent thrombosis vs bare metal stent restenosis: finding the lesser of two evils
    Daniel H Steinberg
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Am Heart Hosp J 5:151-4. 2007
  39. ncbi Biodegradable and bioabsorbable stents
    Ron Waksman
    Washington Hospital Center 110 Irving Street, NW, Suite 4B 1 Washington, DC 20010, USA
    Curr Pharm Des 16:4041-51. 2010
    ....
  40. ncbi Current state of the absorbable metallic (magnesium) stent
    Ron Waksman
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA
    EuroIntervention 5:F94-7. 2009
    ..The preclinical results of the drug-eluting AMS-3 are encouraging and the clinical investigational program will resume in 2010...
  41. ncbi A first-in-man, randomized, placebo-controlled study to evaluate the safety and feasibility of autologous delipidated high-density lipoprotein plasma infusions in patients with acute coronary syndrome
    Ron Waksman
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 55:2727-35. 2010
    ..This study aimed to determine whether serial autologous infusions of selective high-density lipoprotein (HDL) delipidated plasma are feasible and well tolerated in patients with acute coronary syndrome (ACS)...
  42. ncbi Promise and challenges of bioabsorbable stents
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 70:407-14. 2007
    ..Thus, the concept of bioabsorbable stents has emerged as an alternative to permanent metal stents. This review will outline concepts, material designs, preclinical, and initial clinical experimental studies with bioabsorbable stents...
  43. ncbi An innovative noninvasive respiratory stress test indicates significant coronary artery disease
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Cardiovasc Revasc Med 11:20-8. 2010
    ..It is based on spectral analysis of finger pulse wave oscillations measured by photoplethysmography during deep, paced breathing at a rate of six breaths per minute (0.1 Hz) over 70 s...
  44. ncbi Effects of exogenous peripheral-blood-derived endothelial progenitor cells or unfractionated bone-marrow-derived cells on neointimal formation and inflammation in cholesterol-fed, balloon-denuded, and radiated iliac arteries of inbred rabbits
    Ron Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Cardiovasc Revasc Med 10:110-6. 2009
    ....
  45. ncbi Definition, incidence, correlates, and clinical impact of "nuisance" bleeding in patients undergoing drug-eluting stent implantation
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA
    Am J Cardiol 104:30C-3C. 2009
    ..This article discusses the various definitions, incidence, correlates, and clinical impact of this phenomenon...
  46. ncbi Early- and long-term intravascular ultrasound and angiographic findings after bioabsorbable magnesium stent implantation in human coronary arteries
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    JACC Cardiovasc Interv 2:312-20. 2009
    ..This study aimed to evaluate the degradation rate and long-term vascular responses to the absorbable metal stent (AMS)...
  47. ncbi Acute renal failure requiring dialysis after percutaneous coronary interventions
    L Gruberg
    Division of Cardiology, Washington Hospital Center, Washington, D C 20010, USA
    Catheter Cardiovasc Interv 52:409-16. 2001
    ..Thus, acute renal failure that requires dialysis after percutaneous coronary interventions is associated with very high in-hospital and 1-year mortality rates and a dramatic increase in hospital resource utilization...
  48. ncbi Serial intravascular ultrasound assessment of the efficacy of intracoronary gamma-radiation therapy for preventing recurrence in very long, diffuse, in-stent restenosis lesions
    J M Ahmed
    Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Circulation 104:856-9. 2001
    ..005 for all comparisons). CONCLUSIONS:- Serial IVUS analysis shows that gamma-irradiation reduces recurrent in-stent neointimal hyperplasia in long, diffuse ISR lesions; however, it is even more effective when given at a higher dose...
  49. ncbi Intracoronary radiation for patients with refractory in-stent restenosis: an analysis from the WRIST-Crossover Trial. Washington Radiation for In-stent Restenosis Trial
    R Waksman
    Cardiovascular Research Institute, Washington Hospital Center, 20010 DC, USA
    Cardiovasc Radiat Med 1:317-22. 1999
    ..In-stent restenosis (ISR) is a limitation of intracoronary stent implantation. In animal models and clinical trials, ionizing radiation has been shown to decrease in-stent neointimal formation...
  50. ncbi Late total occlusion after intracoronary brachytherapy for patients with in-stent restenosis
    R Waksman
    Cardiac Catheterization Laboratories, Washington Hospital Center, DC, USA
    J Am Coll Cardiol 36:65-8. 2000
    ..The study sought to determine the incidence and predictors of late total occlusion (LTO, >30 days) in-patients with in-stent restenosis who were treated with intracoronary radiation...
  51. ncbi Intracoronary beta-radiation therapy inhibits recurrence of in-stent restenosis
    R Waksman
    Vascular Brachytherapy Institute, Washington Hospital Center, Washington, DC 20010, USA
    Circulation 101:1895-8. 2000
    ..This study, BETA WRIST (Washington Radiation for In-Stent restenosis Trial) was designed to examine the efficacy and safety of the beta-emitter 90-yttrium for the prevention of recurrent ISR...
  52. ncbi Incidence, predictors, and outcome of new, subsequent lesions treated with percutaneous coronary intervention in patients presenting with myocardial infarction
    Gilles Lemesle
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 103:1189-95. 2009
    ..Aggressive preventive and medical management should be applied to this population for prevention of these subsequent events...
  53. ncbi Intracoronary radiation with gamma wire inhibits recurrent in-stent restenosis
    R Waksman
    Washington Hospital Center, 110 Irving Street North West, Suite 4B 1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 2:63-8. 2001
    ..41.8 mm(2); P=.32). Eight patients had a reduction of neointimal intimal tissue at follow-up. These results indicate that intracoronary gamma radiation with the Angiorad source wire is safe and effective in preventing in-stent restenosis...
  54. ncbi Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions
    J M Ahmed
    Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 87:1145-9. 2001
    ..Thus, edge recurrence after (192)Ir treatment of in-stent restenosis is the result of neointimal hyperplasia (part of generalized treatment failure) and the absence of radiation-induced positive remodeling...
  55. ncbi A novel 32P deployable balloon system inhibits formation of neointima in porcine coronary arteries after balloon-overstretching injury
    H S Kim
    Cardiovascular Research Institute, Washington Hospital Center, DC 20010, USA
    Coron Artery Dis 12:317-22. 2001
    ..01). CONCLUSIONS: Intracoronary radiation therapy using a new 32P deployable-balloon system is feasible and safe. A radiation dose of 15 Gy was sufficient to inhibit neointimal response in the porcine coronary-balloon-injury model...
  56. ncbi Edge stenosis and geographical miss following intracoronary gamma radiation therapy for in-stent restenosis
    H S Kim
    Cardiovascular Research Institute, Washington Hospital Center, DC, USA
    J Am Coll Cardiol 37:1026-30. 2001
    ..016). CONCLUSIONS: Edge restenosis following gamma irradiation treatment of ISR is related to GM: a mismatch between the segment of artery injured during the primary catheter-based intervention and the length of the radiation source...
  57. ncbi Prolonged antiplatelet therapy to prevent late thrombosis after intracoronary gamma-radiation in patients with in-stent restenosis: Washington Radiation for In-Stent Restenosis Trial plus 6 months of clopidogrel (WRIST PLUS)
    R Waksman
    Washington Hospital Center, Washington, DC, USA
    Circulation 103:2332-5. 2001
    ..Methods and..
  58. ncbi Delayed re-endothelialization and T-cell infiltration following intracoronary radiation therapy in the porcine model
    M Kollum
    Cardiovascular Research Institute, Washington, DC, USA
    Int J Radiat Oncol Biol Phys 50:495-501. 2001
    ..The elevated apoptosis of these infiltrating T cells may indicate a mechanism for the resolution of inflammation...
  59. ncbi Prognostic value of cardiac troponin I re-elevation following percutaneous coronary intervention in high-risk patients with acute coronary syndromes
    S Fuchs
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 88:129-33. 2001
    ..We conclude that troponin I re-elevation after percutaneous coronary intervention in high-risk patients with ACS is associated with a substantial increase in mortality and reduced event-free survival at 6-month follow-up...
  60. ncbi Treatment of in-stent restenosis
    G S Mintz
    Intravascular Ultrasound Imaging Laboratory, Washington Hospital Center, Washington, DC, USA
    Semin Interv Cardiol 3:117-21. 1998
    ..Vascular brachytherapy has emerged as the most promising way to treat high-risk lesion subsets...
  61. ncbi Usefulness of gamma intracoronary radiation for totally occluded in-stent restenotic coronary narrowing
    Arvind K Sharma
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 91:595-7. 2003
  62. ncbi Creatine kinase-MB fraction elevation after percutaneous coronary intervention in patients with chronic renal failure
    L Gruberg
    Cardiac Catheterization Laboratory, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 87:1356-60. 2001
    ....
  63. ncbi Comparative efficacy of gamma-irradiation for treatment of in-stent restenosis in saphenous vein graft versus native coronary artery in-stent restenosis: An intravascular ultrasound study
    M T Castagna
    Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Circulation 104:3020-2. 2001
    ..1+/-2.1 mm(2) versus 5.6+/-2.2 mm(2), P=0.0067). CONCLUSION: gamma-Irradiation with (192)Ir brachytherapy appears to be as effective in SVGs as it is in native artery ISR lesions...
  64. ncbi Excimer laser coronary angioplasty and intracoronary radiation for in-stent restenosis: six-month angiographic and clinical outcomes
    A E Ajani
    Catheterization Laboratories, Washington Hospital Center, Suite 4B-1, 110 Irving Street Northwest, Washington, DC 20010, USA
    Cardiovasc Radiat Med 2:191-6. 2001
    ..54%, P=.014). CONCLUSION: Radiation therapy with ELCA significantly reduces angiographic binary restenosis at 6 months in patients with diffuse ISR, driven predominantly by reduced percutaneous TVR...
  65. ncbi Effect of direct stenting on clinical outcome in patients treated with percutaneous coronary intervention on saphenous vein graft
    Laurent Leborgne
    Cardiovascular Research Institute, Division of Cardiology, Washington Hospital Center, Washington, DC 20100, USA
    Am Heart J 146:501-6. 2003
    ..021). Multivariate analysis showed that DS (OR = 0.47, P =.007) was associated with reduction of the target lesion revascularization-MACE. CONCLUSIONS: When feasible, DS may be the best approach for treating SVG stenosis...
  66. ncbi An intravascular ultrasound classification of angiographic coronary artery aneurysms
    A Maehara
    Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 88:365-70. 2001
    ..Instead, most angiographically diagnosed aneurysms had the morphology of complex plaques or normal segments with adjacent stenoses...
  67. ncbi Three-year follow-up after intracoronary gamma radiation therapy for in-stent restenosis. Original WRIST. Washington Radiation for In-Stent Restenosis Trial
    A E Ajani
    Washington Hospital Center and Washington Cancer Institute at the Washington Hospital Center, Washington, DC 20010, USA
    Cardiovasc Radiat Med 2:200-4. 2001
    ..65%, P=.003). CONCLUSIONS: In WRIST, patients with ISR treated with IRT using 192Ir had a marked reduction in the need for repeat target lesion and vessel revascularization at 6 months, with the clinical benefit maintained at 3 years...
  68. ncbi Intravascular ultrasound assessment of the stenoses location and morphology in the left main coronary artery in relation to anatomic left main length
    A Maehara
    Intravascular Ultrasound Imaging and Cardiac Catheterization Laboratories, Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 88:1-4. 2001
    ..Most ostial left main stenoses were categorized as eccentric (97% vs 76%, p = 0.01). Short and long left main arteries develop stenoses at different locations. Stenosis morphology was significantly different in these 2 locations...
  69. ncbi Decreased adventitial neovascularization after intracoronary irradiation in swine: a time course study
    M Kollum
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Int J Radiat Oncol Biol Phys 50:1033-9. 2001
    ..Intimal area and adventitial vessel count were correlated positively. Neointima reduction after intracoronary radiation may depend not only on an antiproliferative effect but also on an anti-angiogenic effect...
  70. ncbi Frequency and severity of plaque prolapse within Cypher and Taxus stents as determined by sequential intravascular ultrasound analysis
    Sang-Wook Kim
    Cardiovascular Research Institute/Medstar Research Institute, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 98:1206-11. 2006
    ..However, sequential intravascular ultrasound imaging showed that the frequency and amount of plaque prolapse were neither increased nor decreased by additional higher pressure inflations...
  71. ncbi Differential remodeling after balloon overstretch injury and either beta- or gamma-intracoronary radiation of porcine coronary arteries
    Y Cottin
    Cardiovascular Research Institute, Washington Hospital Center, 110 Irving Street, NW Suite 4B-1, Washington, DC 20010, USA
    Cardiovasc Radiat Med 2:75-82. 2001
    ..These changes in adventitia and neointima appear to contribute to differential vascular remodeling caused by IR in injured vessels...
  72. ncbi Yttrium-90 delivered via a centering catheter and afterloader, given both before and after stent implantation, inhibits neointima formation in porcine coronary arteries
    R Waksman
    Cardiovascular Research Institute, Washington Hospital Center, Suite 4B1, 110 Irving Street, NW, Washington, DC 20010, USA
    Cardiovasc Radiat Med 2:11-7. 2000
    ....
  73. ncbi The effect of intracoronary radiation for the treatment of recurrent in-stent restenosis in patients with chronic renal failure
    L Gruberg
    Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 38:1049-53. 2001
    ..Despite this benefit, patients with renal dysfunction continued to have significantly higher in-hospital and six-month adverse outcomes...
  74. ncbi Intracoronary radiation therapy using a novel beta emitter for in-stent restenosis Tungsten WRIST
    Christian Dilcher
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Cardiovasc Revasc Med 6:52-7. 2005
    ..CONCLUSIONS: Vascular brachytherapy with tungsten (188W) is feasible and safe. The 6-month clinical outcomes are similar to the original WRIST radiation group...
  75. ncbi Intravascular ultrasound analysis of the impact of gamma radiation therapy on the treatment of saphenous vein graft in-stent restenosis
    Marco T Castagna
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 90:1378-81. 2002
  76. ncbi Serial intravascular ultrasound analysis of the impact of lesion length on the efficacy of intracoronary gamma-irradiation for preventing recurrent in-stent restenosis
    J M Ahmed
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Circulation 103:188-91. 2001
    ..378, P:<0.0001). CONCLUSIONS: Brachytherapy may be less effective in longer ISR lesions because of the greater variability and longer source-to-target distances in diffuse ISR...
  77. ncbi Management of severely calcified right coronary artery
    R Lew
    Washington Hospital Center, Washington, DC, USA
    Cardiovasc Radiat Med 4:116-7. 2003
  78. ncbi Efficacy of sirolimus-eluting stents as compared to paclitaxel-eluting stents for saphenous vein graft intervention
    William W Chu
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    J Interv Cardiol 19:121-5. 2006
    ..75). CONCLUSIONS: The use of DES in patients undergoing SVG intervention with a DPD is clinically safe and feasible. As compared to SES, PES have the same efficacy and clinical outcomes in SVG interventions up to 6 months...
  79. ncbi Bivalirudin compared with IIb/IIIa inhibitors in patients with in-stent restenosis undergoing intracoronary brachytherapy
    Pramod Kuchulakanti
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, Washington DC 20010, USA
    Cardiovasc Revasc Med 6:154-9. 2005
    ....
  80. ncbi Prognostic value of cardiac troponin I elevation after percutaneous coronary intervention in patients with chronic renal insufficiency: a 12-month outcome analysis
    Luis Gruberg
    Cardiac Catheterization Laboratory, Cardiovascular Research Institute, Washington Hospital Center, Washington, D C, USA
    Catheter Cardiovasc Interv 55:174-9. 2002
    ..Thus, in patients with CRI, elevated cTnI levels after successful PCI is an important predictor of poor long-term outcome. Our data suggest that patients with cTnI elevation > 3 times above normal values are particularly at higher risk...
  81. ncbi Real-world clinical practice of intracoronary radiation therapy as compared to investigational trials
    Seung-Woon Rha
    Department of Internal Medicine, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 64:61-6. 2005
    ....
  82. ncbi The WRIST series--what have we learnt?
    Andrew E Ajani
    Vascular Brachytherapy Institute, Cardiology Research Institute, Washington Cardiology Center, Washington, DC, USA
    Herz 27:23-9. 2002
    ..AIM: This review is intended to give an overview of the individual trials, summarize pertinent lessons that have been learned and give insight into future of intracoronary radiation...
  83. ncbi The impact of lesion length and reference vessel diameter on angiographic restenosis and target vessel revascularization in treating in-stent restenosis with radiation
    Andrew E Ajani
    Cardiovascular Research Institute, Washington Hospital Center, Washington, D.C, USA
    J Am Coll Cardiol 39:1290-6. 2002
    ....
  84. ncbi Impact of intravascular ultrasound-guided direct stenting on clinical outcome of patients treated for native coronary disease
    Edouard Cheneau
    Washington Hospital Center, 110 Irving Street, NW, Suite 4B-1, Washington, DC, 20010, USA
    Cardiovasc Radiat Med 5:15-9. 2004
    ..25-.85, P = .013) was independently correlated to lower risk for revascularization in multivariate analysis. CONCLUSION: When DS is implemented by IVUS assessment, it is associated with low in-hospital and long-term events...
  85. ncbi Correlates of clinical restenosis following intracoronary implantation of drug-eluting stents
    Probal Roy
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 100:965-9. 2007
    ..In conclusion, correlates of DES ISR included both clinical and procedural factors. Limiting the number of stents and stented length, in addition to intravascular ultrasound guidance, may minimize DES ISR...
  86. ncbi Comparison between sirolimus- and paclitaxel-eluting stents in complex patient and lesions subsets
    Probal Roy
    Division of Cardiology, Washington Hospital Center, Washington DC 20010, USA
    Catheter Cardiovasc Interv 70:167-72. 2007
    ..The data for more complex subsets of patients and lesions remains conflicting. This study aimed to compare SES with PES in a selected population with a broad range of complex features...
  87. ncbi Optimizing dosimetry with high-dose intracoronary gamma radiation (21 Gy) for patients with diffuse in-stent restenosis
    Pramod Kuchulakanti
    Division of Cardiology, Department of Medicine, Washington, DC 20010, USA
    Cardiovasc Revasc Med 6:108-12. 2005
    ....
  88. ncbi The proximal location of stenosis in the left anterior descending coronary artery is not a predictive factor of worse outcome in the era of the stent
    Laurent Leborgne
    Division of Cardiology, Cardiovascular Research Institute, Washington Hospital Center, Suite 4B-1, 110 Irving Street, NW, Washington, DC 20100, USA
    Cardiovasc Radiat Med 3:127-32. 2002
    ..Therefore, when stenting is feasible, the location of the lesion in the LAD is not predictive of worse outcome and, consequently, should not be taken into account in the choice of the revascularization strategy...
  89. ncbi Clinical presentation and outcome of patients hospitalized for symptomatic in-stent restenosis treated by percutaneous coronary intervention: comparison between drug-eluting stents and bare-metal stents
    Axel de Labriolle
    Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 110, Irving Street, NW, Suite 4B 1, Washington DC 20010, USA
    Arch Cardiovasc Dis 102:209-17. 2009
    ..Drug-eluting stents (DES) decrease in-stent restenosis, which is thought to have minimal clinical consequences, but may increase the risk of stent thrombosis and its attendant high mortality rate...
  90. ncbi Impact of sirolimus-eluting stents on outcomes of patients treated for acute myocardial infarction by primary angioplasty
    Edouard Cheneau
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 65:469-72. 2005
    ..14). SESs are safe and effective for the treatment of AMI by primary angioplasty. As compared to BMSs, SESs improve long-term outcome after AMI, mainly by reducing the need for repeat revascularization...
  91. ncbi Bivalirudin-associated intracoronary thrombosis during gamma-brachytherapy and its experimental validation in acute swine model
    Pramod K Kuchulakanti
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 62:209-13. 2004
    ..Cases of intracoronary thrombosis have been reported with beta-radiation when bivalirudin is used as an anticoagulant. We report two cases of intracoronary thrombosis with gamma-radiation when bivalirudin is used...
  92. ncbi Serial volumetric intravascular ultrasound assessment of native coronary artery versus saphenous vein grafts in-stent restenosis lesions after conventional catheter-based treatment
    Javed M Ahmed
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 91:739-41. 2003
  93. ncbi Usefulness of preprocedural coronary lesion morphology as assessed by intravascular ultrasound in predicting Thrombolysis In Myocardial Infarction frame count after percutaneous coronary intervention in patients with Q-wave acute myocardial infarction
    Jun-ichi Kotani
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    Am J Cardiol 91:870-2. 2003
  94. ncbi Asymptomatic late stent thrombosis after sirolimus stent implantation
    Edouard Cheneau
    Washington Hospital Center, Washington, DC 20010, USA
    Cardiovasc Radiat Med 5:57-8. 2004
  95. ncbi Switching from Enoxaparin to Bivalirudin in Patients with Acute Coronary Syndromes without ST-segment Elevation who Undergo Percutaneous Coronary Intervention. Results from SWITCH--a multicenter clinical trial
    Ron Waksman
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    J Invasive Cardiol 18:370-5. 2006
    ....
  96. ncbi Selective versus exclusive use of sirolimus-eluting stent implantation in multivessel coronary artery disease
    William W Chu
    Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Catheter Cardiovasc Interv 65:473-7. 2005
    ....
  97. ncbi Combined mechanical and pharmacological approach to a thrombus-containing lesion
    Itsik Ben-Dor
    Division of Cardiology, Washington Hospital Center, Washington, D C 20010, USA
    Catheter Cardiovasc Interv 75:972-6. 2010
    ..A review of the current literature regarding the drugs and devices available for the prevention and treatment of large thrombus burden has also been performed...
  98. ncbi Treatment of drug-eluting stent restenosis with the same versus different drug-eluting stent
    Shaila Garg
    Department of Cardiology, Washington Hospital Center, Washington, District of Columbia 20010, USA
    Catheter Cardiovasc Interv 70:9-14. 2007
    ..The authors aimed to compare the clinical outcomes with repeat drug-eluting stent (DES) implantation utilizing the same type versus an alternate DES type for in-stent restenosis (ISR) of DES...
  99. ncbi Comparison of ruptured plaques in native coronary arteries and in saphenous vein grafts: an intravascular ultrasound study
    Jerzy Pregowski
    Cardiovascular Research Institute/Medstar Research Institute, Washington Hospital Center, Washington, DC
    Am J Cardiol 97:593-7. 2006
    ..In conclusion, although patients with SVG plaque ruptures are older and have more co-morbidities, the clinical presentation and angiographic and IVUS features are remarkably similar to those of native artery plaque ruptures...
  100. ncbi Intravascular brachytherapy versus drug-eluting stents for the treatment of patients with drug-eluting stent restenosis
    Rebecca Torguson
    Division of Cardiology, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 98:1340-4. 2006
    ..In conclusion, intravascular radiation therapy as adjunct therapy to PCI for patients presenting with ISR of a DES is safe and should be considered an alternative therapeutic option for this difficult subset of patients...
  101. ncbi Intravascular ultrasound parameters associated with stent thrombosis after drug-eluting stent deployment
    Teruo Okabe
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC, USA
    Am J Cardiol 100:615-20. 2007
    ....