Clifford W Zeyl

Summary

Affiliation: Wake Forest University
Country: USA

Publications

  1. ncbi request reprint Experimental studies on ploidy evolution in yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    FEMS Microbiol Lett 233:187-92. 2004
  2. doi request reprint The role of sex in fungal evolution
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, NC 27109, USA
    Curr Opin Microbiol 12:592-8. 2009
  3. ncbi request reprint The advantage of sex in evolving yeast populations
    C Zeyl
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 388:465-8. 1997
  4. ncbi request reprint Evolutionary genetics: a piggyback ride to adaptation and diversity
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Curr Biol 17:R333-5. 2007
  5. ncbi request reprint A short history of recombination in yeast
    Clifford W Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Trends Ecol Evol 22:223-5. 2007
  6. ncbi request reprint Experimental evolution with yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    FEMS Yeast Res 6:685-91. 2006
  7. ncbi request reprint Antagonism between sexual and natural selection in experimental populations of Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, North Carolina 27109, USA
    Evolution 59:2109-15. 2005
  8. ncbi request reprint Nuclear-mitochondrial epistasis for fitness in Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, PO Box 7325, Winston Salem, North Carolina 27109, USA
    Evolution 59:910-4. 2005
  9. pmc The number of mutations selected during adaptation in a laboratory population of Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Genetics 169:1825-31. 2005
  10. ncbi request reprint Capturing the adaptive mutation in yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, NC 27109, USA
    Res Microbiol 155:217-23. 2004

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Experimental studies on ploidy evolution in yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    FEMS Microbiol Lett 233:187-92. 2004
    ..A convincing longer-term advantage for diploidy has proven elusive, and different evolutionary explanations for the origin and for the subsequent maintenance of diploidy may be required...
  2. doi request reprint The role of sex in fungal evolution
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, NC 27109, USA
    Curr Opin Microbiol 12:592-8. 2009
    ....
  3. ncbi request reprint The advantage of sex in evolving yeast populations
    C Zeyl
    Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA
    Nature 388:465-8. 1997
    ....
  4. ncbi request reprint Evolutionary genetics: a piggyback ride to adaptation and diversity
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Curr Biol 17:R333-5. 2007
    ..Competition between adaptive mutations in different asexual lineages limits the rate of adaptation. But additional adaptive mutations can occur in lineages that already have one, altering the dynamics of evolving asexual populations...
  5. ncbi request reprint A short history of recombination in yeast
    Clifford W Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Trends Ecol Evol 22:223-5. 2007
    ....
  6. ncbi request reprint Experimental evolution with yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    FEMS Yeast Res 6:685-91. 2006
    ..This minireview briefly describes some recent contributions of yeast experiments to current understanding of the evolution of ploidy, sex, mutation, and speciation...
  7. ncbi request reprint Antagonism between sexual and natural selection in experimental populations of Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, North Carolina 27109, USA
    Evolution 59:2109-15. 2005
    ..Thus, evolutionary history affected the evolution of genetic correlations, as fitness increases in a population already well adapted to the environment were more likely to come at the expense of sexual functions...
  8. ncbi request reprint Nuclear-mitochondrial epistasis for fitness in Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, PO Box 7325, Winston Salem, North Carolina 27109, USA
    Evolution 59:910-4. 2005
    ..These results indicate that cytonuclear interactions analogous to those already known from plants and animals can evolve rapidly on an evolutionary timescale...
  9. pmc The number of mutations selected during adaptation in a laboratory population of Saccharomyces cerevisiae
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Genetics 169:1825-31. 2005
    ..These backcrosses also indicated that deleterious mutations had hitchhiked with adaptive mutations in this evolved genotype...
  10. ncbi request reprint Capturing the adaptive mutation in yeast
    Clifford Zeyl
    Department of Biology, Wake Forest University, P O Box 7325, Winston Salem, NC 27109, USA
    Res Microbiol 155:217-23. 2004
    ..Estimated rates of adaptive mutation are on the order of 1 in 10(11) cell divisions. There remains great potential for the genomic study of variation within yeast species to contribute to our understanding of adaptive mutation...
  11. ncbi request reprint Budding yeast as a model organism for population genetics
    C Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Yeast 16:773-84. 2000
    ..Conversely, the redundancy of the yeast genome means that, for many open reading frames, deletion has only a quantitative effect that is most readily observed in competitions with a wild-type strain...
  12. pmc Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiae
    C Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Genetics 157:53-61. 2001
    ..Inactivation of mismatch repair increases the frequency of slightly deleterious mutations by approximately two orders of magnitude...
  13. ncbi request reprint Mutational meltdown in laboratory yeast populations
    C Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Evolution 55:909-17. 2001
    ..Wild-type populations showed no trend to decrease in size and, on average, they increased in fitness...
  14. ncbi request reprint An evolutionary advantage of haploidy in large yeast populations
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Science 299:555-8. 2003
    ..Adaptive mutations were on average partially recessive. As predicted, diploidy slowed adaptation by large populations but not by small populations...
  15. ncbi request reprint The effects of sex and mutation rate on adaptation in test tubes and to mouse hosts by Saccharomyces cerevisiae
    Brian Grimberg
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Evolution 59:431-8. 2005
    ..Increased rates of point mutation do not appear to accelerate adaptation...
  16. doi request reprint Prezygotic isolation between Saccharomyces cerevisiae and Saccharomyces paradoxus through differences in mating speed and germination timing
    Helen A Murphy
    Department of Biology, The College of William and Mary, Williamsburg, VA 23187 8795, USA
    Evolution 66:1196-209. 2012
    ..Our results indicate that the mechanisms of allochronic isolation that are well known in plants and animals can also operate in sexual microbes...
  17. ncbi request reprint Evolutionary genetics: choosing to evolve
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Curr Biol 16:R87-9. 2006
    ....
  18. pmc Conflicting levels of selection in the accumulation of mitochondrial defects in Saccharomyces cerevisiae
    Douglas R Taylor
    Department of Biology, University of Virginia, Charlottesville, VA 22904 4328, USA
    Proc Natl Acad Sci U S A 99:3690-4. 2002
    ..The relative intensities of within- and among-cell selection may also explain the tissue specificity of human mitochondrial defects...
  19. pmc Yeast sex: surprisingly high rates of outcrossing between asci
    Helen A Murphy
    Wake Forest University, Winston Salem, North Carolina, United States of America
    PLoS ONE 5:e10461. 2010
    ..Confinement within the ascus is thought to enforce mating between products of the same meiotic division, minimizing outcrossing in this stage of the life cycle...
  20. doi request reprint Evolutionary genetics: desperate times call for more sex
    Clifford Zeyl
    Department of Biology, Wake Forest University, Winston Salem, NC 27109, USA
    Curr Biol 20:R637-9. 2010
    ..A new study has found that strains of the fungus Aspergillus nidulans produce more of their spores sexually in environments where they are less fit, resembling a hypothesized transitional stage in the evolution of sex...