Christopher Paul Turner

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. Turner C, Debenedetto D, Liu C. NMDAR blockade-induced neonatal brain injury: Reversal by the calcium channel agonist BayK 8644. Neurosci Lett. 2009;450:292-5 pubmed publisher
  2. Turner C, Debenedetto D, Ware E, Walburg C, Lee A, Stowe R, et al. MK801-induced activated caspase-3 exhibits selective co-localization with GAD67. Neurosci Lett. 2009;462:152-6 pubmed publisher
    ..These data suggest that whereas somatic expression of AC3 and GAD67 may be non-overlapping, areas that exhibit punctate GAD67 (and are high in synaptic turnover) may be more vulnerable to MK801 exposure. ..
  3. Turner C, Ware E, Stowe R, Debenedetto D, Walburg C, Lee A, et al. Postnatal expression of GAD67. Neurochem Res. 2010;35:254-61 pubmed publisher
    ..In contrast, at P14 and especially P21, both puncta and cell bodies were robustly labeled. Our data indicate that adult-like expression of GAD67 emerges quite late in the postnatal period. ..
  4. Turner C, Debenedetto D, Ware E, Stowe R, Lee A, Swanson J, et al. Postnatal exposure to MK801 induces selective changes in GAD67 or parvalbumin. Exp Brain Res. 2010;201:479-88 pubmed publisher
    ..More importantly, such differential effects may be of great clinical importance, given that cognitive deficits are seen in children exposed to anesthetics that act by blocking the NMDAR. ..
  5. Turner C, Gutierrez S, Liu C, Miller L, Chou J, Finucane B, et al. Strategies to defeat ketamine-induced neonatal brain injury. Neuroscience. 2012;210:384-92 pubmed publisher
    ..These data show that a number of unique approaches can be taken to address anesthesia-induced neurotoxicity in the infant brain, thus providing MDs with a variety of alternative strategies that enhance therapeutic flexibility. ..