Clara R Thore

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Morphometric analysis of arteriolar tortuosity in human cerebral white matter of preterm, young, and aged subjects
    Clara R Thore
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Neuropathol Exp Neurol 66:337-45. 2007
  2. pmc Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 257:62-6. 2007
  3. pmc Microvascular changes in the white mater in dementia
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 283:28-31. 2009
  4. ncbi request reprint Morphometric assessment of collagen accumulation in germinal matrix vessels of premature human neonates
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine Winston Salem, NC 27157, USA
    Neuropathol Appl Neurobiol 31:181-90. 2005
  5. ncbi request reprint Quantification of afferent vessels shows reduced brain vascular density in subjects with leukoaraiosis
    Dixon M Moody
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Radiology 233:883-90. 2004
  6. ncbi request reprint Germinal matrix cells associate with veins and a glial scaffold in the human fetal brain
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Res Dev Brain Res 160:96-100. 2005
  7. ncbi request reprint Immunolocalization of tight junction proteins in blood vessels in human germinal matrix and cortex
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Histochem Cell Biol 127:205-13. 2007
  8. ncbi request reprint Venous collagenosis and arteriolar tortuosity in leukoaraiosis
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 203:159-63. 2002
  9. ncbi request reprint Anatomical analysis of the developing cerebral vasculature in premature neonates: absence of precapillary arteriole-to-venous shunts
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Pediatr Res 52:554-60. 2002
  10. ncbi request reprint Capillary loss precedes the cognitive impairment induced by fractionated whole-brain irradiation: a potential rat model of vascular dementia
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 257:67-71. 2007

Detail Information

Publications16

  1. ncbi request reprint Morphometric analysis of arteriolar tortuosity in human cerebral white matter of preterm, young, and aged subjects
    Clara R Thore
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Neuropathol Exp Neurol 66:337-45. 2007
    ....
  2. pmc Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 257:62-6. 2007
    ..In the four irradiated brains, we found very low vessel densities, similar to those found in LA, without an additional age-related decline...
  3. pmc Microvascular changes in the white mater in dementia
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 283:28-31. 2009
    ..Once the capillaries stop dying, no more string vessels are formed, and the string vessels gradually disappear...
  4. ncbi request reprint Morphometric assessment of collagen accumulation in germinal matrix vessels of premature human neonates
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine Winston Salem, NC 27157, USA
    Neuropathol Appl Neurobiol 31:181-90. 2005
    ..The high incidence of GM haemorrhage in premature neonates may be related to factors other than a deficiency in accumulated collagen...
  5. ncbi request reprint Quantification of afferent vessels shows reduced brain vascular density in subjects with leukoaraiosis
    Dixon M Moody
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Radiology 233:883-90. 2004
    ..To investigate vessel density changes with increasing age in three areas of the brain and to correlate these changes with leukoaraiosis (LA) on the basis of magnetic resonance (MR) images and location in deep white matter (WM)...
  6. ncbi request reprint Germinal matrix cells associate with veins and a glial scaffold in the human fetal brain
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Res Dev Brain Res 160:96-100. 2005
    ..We suggest that the GM cuff cells may represent a distinct subset of GM cells that migrate away from the GM on a pathway consisting of a vein and its associated astrocytic scaffold...
  7. ncbi request reprint Immunolocalization of tight junction proteins in blood vessels in human germinal matrix and cortex
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Histochem Cell Biol 127:205-13. 2007
    ..This maturation could relate to the pathogenesis of germinal matrix hemorrhage-intraventricular hemorrhage...
  8. ncbi request reprint Venous collagenosis and arteriolar tortuosity in leukoaraiosis
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 203:159-63. 2002
    ..In conclusion, our studies support the concept that LA results from chronic ischemia due to age-related vascular pathology...
  9. ncbi request reprint Anatomical analysis of the developing cerebral vasculature in premature neonates: absence of precapillary arteriole-to-venous shunts
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Pediatr Res 52:554-60. 2002
    ..We conclude that precapillary arteriole-to-venous shunts are not a significant factor leading to GMH...
  10. ncbi request reprint Capillary loss precedes the cognitive impairment induced by fractionated whole-brain irradiation: a potential rat model of vascular dementia
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 257:67-71. 2007
    ..Capillary loss may play an important role in radiation-induced dementia and this may be a model of vascular dementia...
  11. ncbi request reprint Vascular damage after fractionated whole-brain irradiation in rats
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Radiat Res 164:662-8. 2005
    ..We suggest that the early (10-week) and persistent vascular damage that occurs after a prolonged whole-brain irradiation fractionation scheme may play an important role in the development of late delayed radiation-induced brain injury...
  12. pmc Reduced ratio of afferent to total vascular density in mesial temporal sclerosis
    Ryan T Mott
    From the Department of Pathology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    J Neuropathol Exp Neurol 68:1147-54. 2009
    ..e. remnants of regressing vasculature) were also observed in Ammon's horn, suggesting vascular degeneration in the MTS hippocampus. These findings may help further our understanding of the pathophysiology of MTS...
  13. ncbi request reprint Increase of white matter string vessels in Alzheimer's disease
    Venkat R Challa
    Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Alzheimers Dis 6:379-83; discussion 443-9. 2004
    ..88 +/- 0.38) compared to controls (1.36 +/- 0.27) (p = 0.0057). This increase in string vessels in the white matter of AD subjects suggests a decrease in vascular supply in this disease...
  14. ncbi request reprint Subependymal veins in premature neonates: implications for hemorrhage
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 2715 7, USA
    Pediatr Neurol 30:46-53. 2004
    ..These data support our suggestion that the structural immaturity of these veins in premature neonates is causally related to the high incidence of germinal matrix hemorrhage in these patients...
  15. ncbi request reprint Apoptosis in leukoaraiosis lesions
    William R Brown
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Neurol Sci 203:169-71. 2002
    ..The apoptosis in the white matter adjacent to the LA lesions suggests progressive cell loss and expansion of the LA lesions...
  16. ncbi request reprint Temporal expression pattern of cerebrovascular endothelial cell alkaline phosphatase during human gestation
    John A Anstrom
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Neuropathol Exp Neurol 61:76-84. 2002
    ..Our measurements indicate that neonates born prior to 28 wk gestation are characterized by immature cerebral white matter afferent vessels and raise the possibility that the immaturity compromises vascular function...