Perry Shen

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Laparoscopic radiofrequency ablation of the liver in proximity to major vasculature: effect of the Pringle maneuver
    Perry Shen
    Department of General Surgery, Wake Forest University School of Medicine, Surgical Oncology Service, Winston Salem, North Carolina 27157, USA
    J Surg Oncol 83:36-41. 2003
  2. ncbi request reprint Factors predicting survival after intraperitoneal hyperthermic chemotherapy with mitomycin C after cytoreductive surgery for patients with peritoneal carcinomatosis
    Perry Shen
    Wake Forest University Baptist Medical Center, Department of General Surgery, Winston Salem, NC 27157, USA
    Arch Surg 138:26-33. 2003
  3. doi request reprint Metastases of colorectal cancer to the liver and peritoneum: comparison of surgical paradigms
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 8:1797-808. 2008
  4. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy with mitomycin C for peritoneal carcinomatosis from nonappendiceal colorectal carcinoma
    Perry Shen
    Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 11:178-86. 2004
  5. ncbi request reprint Pathologic correlation study of microwave coagulation therapy for hepatic malignancies using a three-ring probe
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Gastrointest Surg 11:603-11. 2007
  6. ncbi request reprint Peritoneal surface disease from colorectal cancer: comparison with the hepatic metastases surgical paradigm in optimally resected patients
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Ann Surg Oncol 15:3422-32. 2008
  7. pmc Intraperitoneal chemotherapy for peritoneal surface malignancy: experience with 1,000 patients
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC Electronic address
    J Am Coll Surg 218:573-85. 2014
  8. pmc Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 20:3899-904. 2013
  9. ncbi request reprint Survival and health outcomes after cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of appendiceal origin
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157 1082, USA
    Ann Surg Oncol 15:125-33. 2008
  10. ncbi request reprint Predicting postoperative morbidity following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CS+HIPEC) with preoperative FACT-C (Functional Assessment of Cancer Therapy) and patient-rated performance status
    Chukwuemeka U Ihemelandu
    Section of Surgical Oncology, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 20:3519-26. 2013

Collaborators

Detail Information

Publications77

  1. ncbi request reprint Laparoscopic radiofrequency ablation of the liver in proximity to major vasculature: effect of the Pringle maneuver
    Perry Shen
    Department of General Surgery, Wake Forest University School of Medicine, Surgical Oncology Service, Winston Salem, North Carolina 27157, USA
    J Surg Oncol 83:36-41. 2003
    ..Efficacy of laparoscopic Pringle in proximity to major vasculature has not been well described. Laparoscopic RFA was performed in proximity to major hepatic vessels to examine effects of the Pringle on ablation size and vascular damage...
  2. ncbi request reprint Factors predicting survival after intraperitoneal hyperthermic chemotherapy with mitomycin C after cytoreductive surgery for patients with peritoneal carcinomatosis
    Perry Shen
    Wake Forest University Baptist Medical Center, Department of General Surgery, Winston Salem, NC 27157, USA
    Arch Surg 138:26-33. 2003
    ..Certain clinicopathologic factors predict improved survival after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis...
  3. doi request reprint Metastases of colorectal cancer to the liver and peritoneum: comparison of surgical paradigms
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 8:1797-808. 2008
    ..This review will examine recent evidence regarding these two surgical oncology paradigms and compare patient populations, clinical outcomes and future challenges...
  4. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy with mitomycin C for peritoneal carcinomatosis from nonappendiceal colorectal carcinoma
    Perry Shen
    Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 11:178-86. 2004
    ..We reviewed our experience using this approach for nonappendiceal colorectal cancer (NACC)...
  5. ncbi request reprint Pathologic correlation study of microwave coagulation therapy for hepatic malignancies using a three-ring probe
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Gastrointest Surg 11:603-11. 2007
    ..The ablation time is significantly shorter than other available ablative techniques. Immediate histologic exam produces some evidence of coagulative necrosis. Further study of this promising technology is warranted...
  6. ncbi request reprint Peritoneal surface disease from colorectal cancer: comparison with the hepatic metastases surgical paradigm in optimally resected patients
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Ann Surg Oncol 15:3422-32. 2008
    ..We examined our experience with cytoreductive surgery (CS) and intraperitoneal hyperthermic chemotherapy (IPHC) for peritoneal surface disease (PSD) compared with liver resection for HM...
  7. pmc Intraperitoneal chemotherapy for peritoneal surface malignancy: experience with 1,000 patients
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC Electronic address
    J Am Coll Surg 218:573-85. 2014
    ..To treat carcinomatosis, we use cytoreductive surgery (CS) with hyperthermic intraperitoneal chemotherapy (HIPEC)...
  8. pmc Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 20:3899-904. 2013
    ..It is estimated that 37% of the U.S. population is obese. It is unknown how obesity influences the operative and survival outcomes of cytoreductive surgery (CRS)/hyperthermic intraperitoneal chemotherapy (HIPEC) procedures...
  9. ncbi request reprint Survival and health outcomes after cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of appendiceal origin
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157 1082, USA
    Ann Surg Oncol 15:125-33. 2008
    ..This aggressive therapy may impair patient quality of life (QOL). The purpose of this study was to monitor health outcomes before and after treatment...
  10. ncbi request reprint Predicting postoperative morbidity following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CS+HIPEC) with preoperative FACT-C (Functional Assessment of Cancer Therapy) and patient-rated performance status
    Chukwuemeka U Ihemelandu
    Section of Surgical Oncology, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 20:3519-26. 2013
    ..One goal of our ongoing patient-reported health-related quality of life (HRQoL) program is to describe the prognostic value of HRQoL measures for predicting postoperative morbidity and mortality following CS+HIPEC...
  11. ncbi request reprint Monitoring health outcomes following cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University, School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 14:1105-13. 2007
    ..It is associated with physical and psychological morbidity. The purpose of this study was to monitor health outcomes related to treatment...
  12. pmc Intraoperative imprint cytologic evaluation of sentinel lymph nodes for lobular carcinoma of the breast
    Andrew J Creager
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27157, USA
    Ann Surg 239:61-6. 2004
    ..We are unaware of any large published studies, using any technique, to evaluate SLN for lobular carcinoma...
  13. pmc Perioperative systemic chemotherapy for appendiceal mucinous carcinoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Aaron U Blackham
    Department of General Surgery, Wake Forest School of Medicine, Winston Salem, North Carolina
    J Surg Oncol 109:740-5. 2014
    ..The role of systemic chemotherapy (SC) in conjunction with cytoreductive surgery (CS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in appendiceal mucinous carcinoma peritonei (MCP) is unknown...
  14. pmc Survival and quality of life following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colonic origin
    Adrienne R Hill
    Section of Hematology and Oncology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 18:3673-9. 2011
    ..Cytoreductive surgery (CS) with hyperthermic intraperitoneal chemotherapy (HIPEC) offers patients the prospect of long-term survival with alleviation of symptoms...
  15. ncbi request reprint Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for advanced gastric cancer
    Jason J Hall
    Department of Surgery, Comprehensive Cancer Center of Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    J Gastrointest Surg 8:454-63. 2004
    ..Careful patient selection for this procedure is imperative, and patients in whom an R0/R1 resection can be achieved are the best candidates...
  16. ncbi request reprint Intraoperative evaluation of sentinel lymph nodes for metastatic melanoma by imprint cytology
    Victoria Soo
    Surgical Oncology Service and Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 14:1612-7. 2007
    ..There is a paucity of literature on intraoperative imprint cytology (IIC) evaluation of the SLN in melanoma. The purpose of this article is to present an update to our experience with IIC for SLN in melanoma...
  17. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: experience with 501 procedures
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Am Coll Surg 204:943-53; discussion 953-5. 2007
    ..We have been using aggressive cytoreductive surgery with intraperitoneal hyperthermic chemotherapy (IPHC) to treat PSD. The purpose of this article was to review our experience with IPHC...
  18. pmc Optimal timing of systemic therapy in resectable colorectal liver metastases
    Chukwuemeka Ihemelandu
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 79:414-21. 2013
    ..Adjuvant only systemic therapy was associated with an improved survival in resectable CLM. Prospective randomized trials are needed to confirm these findings...
  19. ncbi request reprint Comparison of standard distal pancreatectomy and splenectomy with radical antegrade modular pancreatosplenectomy
    Paul Trottman
    Department of General Surgery and Biostatistics, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Am Surg 80:295-300. 2014
    ..It should be the preferred surgical approach when lymph node count is important for tumor staging. ..
  20. pmc Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from rectal cancer
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 20:1088-92. 2013
    ..Yet the efficacy of HIPEC in rectal patients is controversial because of the retroperitoneal location of the primary tumor. Therefore, we reviewed our experience in patients with PC from a rectal primary tumor...
  21. ncbi request reprint Outcomes associated with cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in colorectal cancer patients with peritoneal surface disease and hepatic metastases
    Oliver Varban
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer 115:3427-36. 2009
    ..The purpose of the current study was to compare the overall survival of patients with HM to those without and to examine predictive factors...
  22. pmc A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers
    John H Stewart
    Department of General Surgery, Surgical Oncology Service, Medical Center Blvd, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Ann Surg Oncol 15:2137-45. 2008
    ..Therefore, we undertook a phase I evaluation of IPHC with oxaliplatin for peritoneal dissemination from colorectal and appendiceal cancers to establish the dose-limiting toxicity (DLT) and the maximum tolerated dose (MTD)...
  23. ncbi request reprint Long-term survivorship and quality of life after cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, The Surgical Oncology Service, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Ann Surg Oncol 10:155-62. 2003
    ..The purpose of this study was to measure the quality of life (QOL) of survivors (>3 years) after treatment...
  24. ncbi request reprint Impact of sentinel lymph node biopsy on immediate breast reconstruction after mastectomy
    Benjamin C Wood
    Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 75:551-6; discussion 556-7. 2009
    ....
  25. pmc Outcomes of Cytoreductive Surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients older than 70 years; survival benefit at considerable morbidity and mortality
    Konstantinos I Votanopoulos
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 20:3497-503. 2013
    ..Yet, for elderly patients (older than 70 years of age) CRS/HIPEC is controversial, due to associated morbidity...
  26. pmc A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C
    Konstantinos Votanopoulos
    Department of General Surgery, Surgical Oncology Section, Wake Forest School of Medicine, Winston Salem, North Carolina
    J Surg Res 179:e133-9. 2013
    ..Our goal in this study is to present a single institution's experience with the hematologic toxicities of the two agents...
  27. pmc Is intraoperative imprint cytology evaluation still feasible for the evaluation of sentinel lymph nodes for lobular carcinoma of the breast?
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 19:929-34. 2012
    ..Intraoperative imprint cytology (IIC) is a rapid, reliable method for evaluating SLNs intraoperatively. We sought to reexamine our experience with this technique in the identification of invasive lobular breast cancer SLN metastases...
  28. ncbi request reprint Use of sentinel lymph node biopsy for melanoma of the head and neck
    Lauren A Kilpatrick
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 73:754-8; discussion 758-9. 2007
    ..However, rates of nodal positivity are similar to melanoma of the trunk and extremities. Therefore, despite being more demanding, SLN is useful in diagnosis and treatment of melanomas of the head and neck...
  29. ncbi request reprint Intraoperative imprint cytology for evaluation of sentinel lymph nodes from Merkel cell carcinoma
    S Lindsey Wong
    Department of General Surgery Surgical Oncology Service, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 75:615-9. 2009
    ..SLN mapping has usefulness in patients with MCC. IIC is feasible and accurate in evaluating the SLN. IIC is a practical diagnostic tool when intraoperative analysis of SLN biopsy is desired for MCC...
  30. doi request reprint Prevention of surgical site infections in high-risk patients with laparotomy incisions using negative-pressure therapy
    Aaron U Blackham
    Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
    Am J Surg 205:647-54. 2013
    ..This study evaluates the efficacy of negative-pressure therapy (NPT) in preventing surgical site infections (SSIs) in high-risk surgical oncology patients...
  31. pmc Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma
    Yankai Sun
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 79:644-8. 2013
    ..However, even with such advancement in management, treatment for small bowel adenocarcinoma still remains a challenge...
  32. pmc Outcomes of repeat cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal surface malignancy
    Konstantinos I Votanopoulos
    Surgical Oncology Service, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
    J Am Coll Surg 215:412-7. 2012
    ..Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival of patients with peritoneal surface malignancy. On recurrence, a repeat CRS/HIPEC is a treatment option...
  33. pmc Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, NC 27157, USA
    J Am Coll Surg 214:599-606; discussion 606-7. 2012
    ..This study uses gene expression analysis of peritoneal metastases to better understand these neoplasms...
  34. ncbi request reprint Does shave biopsy accurately predict the final breslow depth of primary cutaneous melanoma?
    Phillip Moore
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am Surg 75:369-73; discussion 374. 2009
    ..SB is a valuable tool for practitioners in the diagnosis of melanoma. Nevertheless, patients diagnosed with melanoma by SB should be counseled about the rare need for additional surgery...
  35. ncbi request reprint Nodal melanocytic nevi in sentinel lymph nodes. Correlation with melanoma-associated cutaneous nevi
    John B Holt
    Department of Pathology, Duke University Medical Center, Durham, NC, USA
    Am J Clin Pathol 121:58-63. 2004
    ..The increased frequency of nodal nevi in SLNs relative to non-SLNs suggests an etiology of mechanical transport of nevus cells...
  36. doi request reprint Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for malignant peritoneal mesothelioma: mitomycin versus cisplatin
    Aaron U Blackham
    Surgical Oncology Service, Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 17:2720-7. 2010
    ..The most efficacious chemotherapy regimen is not established. Herein we report clinical outcomes of MPM patients treated with CS and IPHC and contrast results using two chemoperfusates: mitomycin and cisplatin...
  37. ncbi request reprint Use of sentinel node mapping for cancer of the colon: 'to map or not to map"
    Kristen A Thomas
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 72:606-11; discussion 611-2. 2006
    ..We do not suggest routine utilization of SLN mapping for colon cancer, but we believe that the data supports proceeding with a national trial...
  38. ncbi request reprint Sentinel lymph node mapping for gastric adenocarcinoma
    Robert D Becher
    Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27010, USA
    Am Surg 75:710-4. 2009
    ..Additionally, our study shows no utility in identifying micrometastatic disease with immunohistochemical techniques. Although a promising modality, we do not recommend the clinical use of SLN mapping for gastric cancer...
  39. ncbi request reprint Appendiceal neoplasms with peritoneal dissemination: outcomes after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy
    John H Stewart
    Department of General Surgery, Surgical Oncology Service, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 13:624-34. 2006
    ..Few data have correlated outcome with appendiceal histology after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy (IPHC). We have reviewed our experience with cytoreductive surgery and IPHC for PD from the appendix...
  40. ncbi request reprint Use of FDG-PET imaging for patients with disseminated cancer of the appendix
    Payam Rohani
    Surgical Oncology Service, Department of General Surgery, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am Surg 76:1338-44. 2010
    ..PET imaging has limited use for patients with PDA. We do not recommend the use of FDG-PET for patients with PDA from cancer of the appendix...
  41. doi request reprint Race and recurrence in women who undergo neoadjuvant chemotherapy for breast cancer
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am J Surg 205:397-401. 2013
    ..Black women can have worse outcomes than white women with breast cancer. We examined survival in black and white women who received neoadjuvant chemotherapy...
  42. pmc Patient rated outcomes and survivorship following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CS + HIPEC)
    Katharine E Duckworth
    Internal Medicine, Wake Forest Baptist Health, Winston Salem, North Carolina 27157, USA
    J Surg Oncol 106:376-80. 2012
    ..The purpose of this study was to record patient rated outcomes and the HRQOL of long-term survivors...
  43. pmc Outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface dissemination from ovarian neoplasms
    E Nicole Parson
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Surg 202:481-6. 2011
    ..This work represents a review of the authors' institution's experience with HIPEC for PSD from OC...
  44. ncbi request reprint Recurrence after mastectomy for ductal carcinoma in situ
    Laura N Godat
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 75:592-5; discussion 595-7. 2009
    ..We recommend SLN biopsy without intraoperative touch prep analysis. Additional treatment may not be required in patients with microinvasion, positive or close margins because our series shows no local recurrence in these patients...
  45. ncbi request reprint Intraoperative imprint cytology for evaluation of sentinel lymph nodes from visceral malignancies
    Edward A Levine
    Surgical Oncology Service, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Gastrointest Surg 7:687-91. 2003
    ..If there is a negative result, the technique may miss disease that is present on subsequent permanent sections. We do not recommend routine use of IIC; however, it may be of use in clinical trials...
  46. ncbi request reprint Futility of fluorodeoxyglucose F 18 positron emission tomography in initial evaluation of patients with T2 to T4 melanoma
    Paige B Clark
    Department of Nuclear Medicine, Surgical Oncology Service, Wake Forest University Health Sciences, Winston Salem, NC, USA
    Arch Surg 141:284-8. 2006
    ..The reported diagnostic yield of whole-body conventional radiological imaging in initial staging of patients with melanoma is low. However, the diagnostic yield of positron emission tomography (PET) for distant metastases is unclear...
  47. ncbi request reprint Intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: current status and future directions
    John H Stewart
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 12:765-77. 2005
    ..The advancement of centers of excellence and the initiation of further phase II trials will help to define the optimal treatment approach for peritoneal carcinomatosis...
  48. ncbi request reprint Effect of massage technique on sentinel lymph node mapping for cancer of the breast
    Georgia Haynes
    Surgical Oncology Service, Department of Surgery, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Am Surg 69:520-2. 2003
    ..Our results failed to demonstrate a superior breast massage technique for identifying sentinel nodes. A larger randomized trial is needed to confirm these findings...
  49. pmc Management of peritoneal carcinomatosis from colorectal cancer
    Chukwuemeka U Ihemelandu
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Semin Oncol 38:568-75. 2011
    ..This review will examine recent evidence pertaining to the evolving surgical oncology paradigm for management of colorectal peritoneal carcinomatosis...
  50. ncbi request reprint Leiomyosarcoma of the inferior vena cava: surgical management and clinical results
    Jason Dew
    Wake Forest University School of Medicine, Department of Surgery, Surgical Oncology, Vascular Surgery Service, Winston Salem, North Carolina 27157, USA
    Am Surg 71:497-501. 2005
    ..The management of the IVC can be managed with primary repair, ligation, or prosthetic graft. Long-term survival is possible if complete resection can be achieved...
  51. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma
    Samuel P Jacks
    Surgical Oncology Service of the Department of General Surgery and the Department of Public Health Sciences, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Surg Oncol 91:112-7; discussion 118-9. 2005
    ..Due to the rarity, poor prognosis, and lack of standard treatment, we chose to review our experience with this disease process treated with cytoreductive surgery (CS) and intraperitoneal hyperthermic chemotherapy (IPHC)...
  52. pmc Efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in the management of malignant ascites
    Reese W Randle
    Surgical Oncology Service in the Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 21:1474-9. 2014
    ..The role of cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in controlling malignant ascites is not well defined...
  53. pmc Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal sarcomatosis
    Reese W Randle
    Surgical Oncology Service in the Department of General Surgery, Wake Forest University, Winston Salem, North Carolina, USA
    Am Surg 79:620-4. 2013
    ..Although a complete cytoreduction is related to improved survival, the role of HIPEC in these patients is unknown. A multi-institutional review will help define the role of CRS-HIPEC in this population...
  54. doi request reprint Current status and future directions in appendiceal cancer with peritoneal dissemination
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Surg Oncol Clin N Am 21:599-609. 2012
    ..Finally, future challenges for the use of hyperthermic intraperitoneal perfusion for appendiceal primary tumors are explored...
  55. doi request reprint Intraperitoneal hyperthermic chemotherapy: an evolving paradigm for the treatment of peritoneal surface malignancies
    John H Stewart
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 8:1809-18. 2008
    ..The present review will outline the rationale, current practice and future directions of IPHC in the management of peritoneal surface malignancies...
  56. ncbi request reprint Staging and current treatment of hepatocellular carcinoma
    Hollins P Clark
    Department of Radiology, Wake Forest University School of Medicine, Meads Hall, 2nd Floor, Medical Center Blvd, Winston Salem, NC 27157 1088, USA
    Radiographics 25:S3-23. 2005
    ..To participate effectively in this effort, radiologists must be familiar with staging and treatment options for HCC and with the factors that affect the choice of management method...
  57. pmc Significance of urinary tract involvement in patients treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)
    Konstantinos I Votanopoulos
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 21:868-74. 2014
    ..The impact of these combined procedures on surgical outcomes is not well defined...
  58. ncbi request reprint Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration
    Girish Mishra
    Department of Internal Medicine, Section of Gastroenterology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Gastrointest Endosc 63:648-54. 2006
    ..Telomerase activity is up-regulated in pancreatic cancer. Hence, measurement of telomerase activity in pancreatic needle-biopsy specimens could assist in establishing a positive diagnosis in specimens that are inadequate for cytology...
  59. ncbi request reprint Lymphatic mapping for gastric adenocarcinoma
    Jon C Hundley
    Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 68:931-5. 2002
    ..However, SLN negativity does not definitively prove that the remaining nodal basin is free of disease (negative predictive value 50%). Lymphatic mapping for gastric carcinoma is a promising technique worthy of further investigation...
  60. ncbi request reprint Cryosurgery of close or positive margins after hepatic resection for primary and metastatic hepatobiliary malignancies
    Perry Shen
    Department of General Surgery, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Am Surg 68:695-703; discussion 703. 2002
    ..Because disease recurrence at the cryoablated margin is low this technique may allow more patients to undergo effective surgical treatment of their hepatobiliary cancers...
  61. ncbi request reprint Pleuropulmonary involvement in pseudomyxoma peritonei: morphologic assessment and literature review
    Kim R Geisinger
    Department of Pathology, Wake Forest University School of Medicine and the North Carolina Baptist Hospital, Winston Salem, NC 27157 1072, USA
    Am J Clin Pathol 127:135-43. 2007
    ..The smear backgrounds contained wispy mucin. None of the 5 patients developed thoracic lymph nodal metastases. Although rare, mucinous neoplasms from PP may involve the thorax...
  62. ncbi request reprint Outcome after mastectomy for ipsilateral breast tumor recurrence after breast conserving surgery
    H Randall Beard
    Surgical Oncology Service of Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 76:829-34. 2010
    ..Mastectomy for IBTR remains effective treatment for most patients, but the risk of PMR remains. Patients with IBTR tumors >2 cm have an increased risk of PMR. Strict follow-up should be routine, especially during the first 24 months...
  63. pmc Splenectomy ameliorates hematologic toxicity of hyperthermic intraperitoneal chemotherapy
    Robert D Becher
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC
    J Gastrointest Oncol 2:70-6. 2011
    ..Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is a promising modality for peritoneal carcinomatosis. Splenectomy is frequently required, however effect upon hematotoxicity is unknown...
  64. ncbi request reprint Intraoperative analysis of sentinel lymph nodes by imprint cytology for cancer of the breast
    Stephen A Shiver
    Department of Surgery, Surgical Oncology Service, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Am J Surg 184:424-7. 2002
    ..The optimal technique for rapid SLN assessment has not been determined. Both frozen sectioning and imprint cytology are used for rapid intraoperative SLN evaluation...
  65. ncbi request reprint Complications from radiofrequency ablation of liver metastases
    Ronald J Zagoria
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1088, USA
    Am Surg 68:204-9. 2002
    ..We conclude that radiofrequency ablation of liver metastases is associated with a low rate of serious complications (two of 38; 5%). Complications requiring treatment usually develop several days after the procedure...
  66. ncbi request reprint Biopsy needle technique and the accuracy of diagnosis of atypical ductal hyperplasia for mammographic abnormalities
    Li Zhao
    Surgical Oncology Services, Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 69:757-62; discussion 762. 2003
    ..Although the risk of understaging ADH is lower with the VACB, we continue to recommend excisional biopsy in a good-risk patient when a diagnosis of ADH is rendered via VACB biopsy...
  67. ncbi request reprint Tissue-dependent and -independent gene expression changes in metastatic colon cancer
    William H Gmeiner
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Oncol Rep 19:245-51. 2008
    ..These expression level changes complement the spectrum of mutations that characterize the progression of colorectal cancer...
  68. ncbi request reprint Evaluation of liver metastases after radiofrequency ablation: utility of 18F-FDG PET and PET/CT
    David W Barker
    Department of Radiology, Wake Forest University, Medical Center Blvd, Winston Salem, NC 27157, USA
    AJR Am J Roentgenol 184:1096-102. 2005
    ..CONCLUSION: (18)F-FDG PET and PET/CT can provide added diagnostic information compared with conventional imaging in patients after radiofrequency ablation of liver metastases and can be useful in guiding repeat ablation procedures...
  69. ncbi request reprint Intraperitoneal hemorrhage in a patient with hepatic focal nodular hyperplasia
    Mario P DeMarco
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 72:555-9. 2006
    ..We suggest that although FNH is a benign lesion and intervention is typically unnecessary, the potential for rupture requiring surgical resection should always be considered...
  70. ncbi request reprint Acceleration of Integra incorporation in complex tissue defects with subatmospheric pressure
    Joseph A Molnar
    Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157 1075, USA
    Plast Reconstr Surg 113:1339-46. 2004
    ..Application of subatmospheric pressure improved the take rate and time to vascularization of Integra, compared with previous published results, even with complicated wounds. This technique may be a practical alternative to flap closure...
  71. ncbi request reprint Breast cancer recurrences in elderly patients after lumpectomy
    Shuchi Shah
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 68:735-9. 2002
    ..This supports similar treatment patterns recommended for younger patients. Women over 65 years of age should be carefully evaluated for adjuvant therapy...
  72. ncbi request reprint Sentinel lymph node biopsy in a young child with thick cutaneous melanoma
    Marc Bisseck
    General Surgery Resident PGY4, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina, USA
    Oncology (Williston Park) 17:1003-5; discussion 1006-10. 2003
    ..In the adult population, sentinel lymph node biopsy has emerged as a less morbid yet accurate method of staging regional lymph nodes. This innovative technique can also be used in the pediatric population...
  73. ncbi request reprint Intraoperative evaluation of sentinel lymph nodes for metastatic melanoma by imprint cytology
    Andrew J Creager
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA
    Cancer 94:3016-22. 2002
    ..The purpose of the current study was to evaluate the utility of IIC in patients undergoing SLN for melanoma...
  74. ncbi request reprint Peritoneal carcinomatosis: what can we do about it?
    Perry Shen
    J Clin Oncol 22:202; author reply 203. 2004
  75. ncbi request reprint Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial
    Anton J Bilchik
    Department of Gastrointestinal Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, and Michigan State University McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg 246:568-75; discussion 575-7. 2007
    ..6% rate of micrometastases (MM) identified by immunohistochemical staining (IHC) of H&E-negative SNs in CC. We hypothesized that these MM have prognostic importance...
  76. ncbi request reprint Intraoperative evaluation of sentinel lymph nodes for metastatic breast carcinoma by imprint cytology
    Andrew J Creager
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Mod Pathol 15:1140-7. 2002
    ..The purpose of this study is to evaluate experience with imprint cytology for intraoperative evaluation of sentinel lymph nodes in patients with breast cancer...
  77. ncbi request reprint Pilot clinical trial of 18F-fluorodeoxyglucose positron-emission mammography in the surgical management of breast cancer
    Lorraine Tafra
    The Breast Center, Anne Arundel Health Systems, 2002 Medical Parkway, Suite 120, Annapolis, MD 21401, USA
    Am J Surg 190:628-32. 2005
    ..High-resolution positron-emission mammography (PEM) is a new device, which allows the imaging of breast tissue. A prospective study was performed to assess the accuracy of PEM in newly diagnosed breast cancer patients...