Research Topics
| D G RirieSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Time-dependent perioperative anesthetic management and outcomes of the first 100 consecutive cases of spring-assisted surgery for sagittal craniosynostosisDouglas G Ririe
Department of Anesthesiology, Wake Forest School of Medicine, Winston Salem, NC, USA
Paediatr Anaesth 21:1015-9. 2011..The effect of number of procedures was also tested on hematocrit postoperative day 1 (POD1), anesthesia time, and surgery time of the first procedure...
Electrophysiologic characteristics of large neurons in dorsal root ganglia during development and after hind paw incision in the ratDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesthesiology 109:111-7. 2008..The authors hypothesized that these differences result in part from changes in intrinsic electrophysiologic properties of large neurons...
Age-dependent responses to nerve injury-induced mechanical allodyniaDouglas G Ririe
Department of Anesthesiology, and Center for the Study of Pharmacologic Plasticity in the Presence of Pain, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Anesthesiology 104:344-50. 2006....
Transfusion-related acute lung injury in an infant during craniofacial surgeryDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1009, USA
Anesth Analg 101:1003-6, table of contents. 2005..Understanding the pathophysiology may help make an earlier diagnosis to reduce more serious adverse outcomes...
Comparison of the immediate effects of surgical incision on dorsal horn neuronal receptive field size and responses during postnatal developmentDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1009, USA
Anesthesiology 109:698-706. 2008..The authors hypothesize that the spatial activation and intensity of dorsal horn neuron responses to skin incision differ in immature and adult spinal cord...
Effect of cyclooxygenase-1 inhibition in postoperative pain is developmentally regulatedDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009, USA
Anesthesiology 101:1031-5. 2004
Preoperative sciatic nerve block decreases mechanical allodynia more in young rats: is preemptive analgesia developmentally modulated?Douglas G Ririe
Department of Anesthesiology and Center for the Study of Pharmacologic Plasticity in the Presence of Pain, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesth Analg 99:140-5. 2004..These results suggest that preoperative SNB in young animals provides a preemptive analgesic effect on mechanical allodynia that is age or developmentally dependent...
Surgical advancement influences perioperative care: a comparison of two surgical techniques for sagittal craniosynostosis repairDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesth Analg 97:699-703. 2003..The reduction in blood loss with this new surgical treatment is significant for the patient in reducing blood transfusion and for the anesthesiologist in reducing concerns of volume resuscitation...
Age-dependent responses to thermal hyperalgesia and mechanical allodynia in a rat model of acute postoperative painDouglas G Ririe
Department of Anesthesiology and Center for the Study of Pharmacologic Plasticity in the Presence of Pain, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesthesiology 99:443-8. 2003..The purpose of the present study was to examine postoperative responses in rats of developmental ages paralleling the infant to young adult human...
The pharmacokinetics of epsilon-aminocaproic acid in children undergoing surgical repair of congenital heart defectsDouglas G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesth Analg 94:44-9, table of contents. 2002..Based on these data, a dosing modification in children is suggested which may better maintain serum concentrations in children when compared with adults...
Direct effects of propofol on myocardial and vascular tissue from mature and immature ratsD G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
J Cardiothorac Vasc Anesth 15:745-9. 2001..To determine the effect of age on the direct myocardial and vascular effects of propofol in rats...
Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile ratsM Danilo Boada
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1009, USA
J Neurophysiol 104:3568-75. 2010..Additionally, these results highlight potential limitations of using passive electrical properties and conduction velocity alone to characterize primary afferents without knowledge of the skin type they innervated...
Video-assisted ductal ligation in premature infantsMichael H Hines
Department of Cardiothoracic Surgery, Brenner Children s Hospital, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina, USA
Ann Thorac Surg 76:1417-20; discussion 1420. 2003..We have applied this technique in low birth weight premature infants and now report our experience...
Assessment of behavior during labor in rats and effect of intrathecal morphineChuanyao Tong
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Anesthesiology 108:1081-6. 2008..To address this, the authors classified and quantified spontaneous behaviors during labor and delivery in rats and examined the effects of a known analgesic, intrathecal morphine...
Developmental differences in spinal cyclooxygenase 1 expression after surgical incisionDouglas G Ririe
Department of Anesthesiology and Center for the Study of Pharmacological Plasticity in the Presence of Pain, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1009, USA
Anesthesiology 104:426-31. 2006....
The antinociceptive effects of spinal cyclooxygenase inhibitors on uterine cervical distensionDongping Du
Pain Mechanism Laboratory, Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA
Brain Res 1024:130-6. 2004..None of the inhibitors altered hemodynamic response to uterine cervical distension. The study suggests that targeting spinal COX-2 could be useful to treat transient and acute visceral pain from the uterine cervix...
Vasodilatory actions of the dietary peptide carnosineD G Ririe
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
Nutrition 16:168-72. 2000..The effect of carnosine is at least in part mediated via cyclic GMP production and is not reproduced by its constituent amino acids, L-histidine and beta-alanine...
Vagal hypertonia and anesthesia in Angelman syndromeJeffrey C Gardner
Paediatr Anaesth 18:348-9. 2008
A well-fertilized bulb should blossomTimothy E Smith
Anesth Analg 99:622. 2004
Research Grants
- Neurophysiologic Development Responses to SurgeryDOUGLAS RIRIE; Fiscal Year: 2007..Through this and future studies which come from this data and training, improvement in understanding will hopefully lead to improved pain therapy that is developmentally appropriate. ..
