Research Topics
| Stephen RappSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Social coping strategies associated with quality of life decrements among psoriasis patientsS R Rapp
Department of Psychiatry, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
Br J Dermatol 145:610-6. 2001..Individuals with psoriasis often report significant psychological distress, physical disability, social strain and reduced quality of life. Little is known about how they cope with the illness...- The promise and challenge of new biological treatments for psoriasis: how do they impact quality of life?Stephen R Rapp
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Dermatol Ther 17:376-82. 2004..These measures have been used to show the benefits new biologic medications offer our patients... - The Acne Quality of Life Index (Acne-QOLI): development and validation of a brief instrumentStephen R Rapp
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Am J Clin Dermatol 7:185-92. 2006..Assessing the impact of acne on quality of life requires well-validated and reliable measures of acne-specific quality of life that are brief and easy to administer and interpret... - Baseline experience with Modified Mini Mental State Exam: The Women's Health Initiative Memory Study (WHIMS)S R Rapp
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Aging Ment Health 7:217-23. 2003..Despite relatively narrow distributions in WHIMS, baseline 3MS scores retained associations with age and education. These associations varied among ethnic groups, so that care must be taken in comparing data across populations... - Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trialStephen R Rapp
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 289:2663-72. 2003..On July 8, 2002, the estrogen plus progestin therapy in the WHI trial was discontinued because of certain increased health risks for women... - Memory enhancement training for older adults with mild cognitive impairment: a preliminary studyS Rapp
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Wake Forest University 27157, USA
Aging Ment Health 6:5-11. 2002..Findings suggest that individuals with MCI can benefit from multi-component memory enhancement training. Further development of such training programs and tests of their efficacy alone and in combination with medications are needed... 
Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: the Seniors Health and Activity Research Program Pilot (SHARP-P) study, a randomized controlled trialClaudine Legault
Division of Public Health Sciences, Department of Biostatistical Sciences Wachovia 21st floor, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
BMC Geriatr 11:27. 2011..Before definitive trials are mounted, important design questions on participation/adherence, training and interventions effects must be answered to more fully inform a full-scale trial...- Long-term effects of conjugated equine estrogen therapies on domain-specific cognitive function: results from the Women's Health Initiative study of cognitive aging extensionMark A Espeland
Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
J Am Geriatr Soc 58:1263-71. 2010..To determine whether small decrements in global cognitive function that conjugated equine estrogen (CEE) therapies have been shown to produce in older women persist after cessation and extend to specific cognitive domains... 
Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) studyMark A Espeland
Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
Int J Geriatr Psychiatry 26:135-43. 2011..To examine the performance of the Telephone Interview for Cognitive Status (TICS) for identifying participants appropriate for trials of physical activity and cognitive training interventions...- Benchmarks for designing two-stage studies using modified mini-mental state examinations: experience from the Women's Health Initiative Memory StudyMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Clin Trials 3:99-106. 2006..The modified mini-mental state examination (3MS) is commonly used as this initial screen in such two-stage designs, however its properties for this role require further study... - Association between alcohol intake and domain-specific cognitive function in older womenMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Neuroepidemiology 27:1-12. 2006..However, our observational study cannot rule out confounding associations with unmeasured factors... - Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition studyHal H Atkinson
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Gerontol A Biol Sci Med Sci 62:844-50. 2007..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults... - Symptom clusters in patients with newly-diagnosed brain tumorsJohn F Gleason
Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Support Oncol 5:427-33, 436. 2007..Our results suggest that interventions that target both cognitive function and mood should be considered in this patient population. Further research on symptom clusters in brain tumor patients is needed... - Self report of skin problems among farmworkers in North CarolinaQuirina M Vallejos
Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1084, USA
Am J Ind Med 51:204-12. 2008..This study estimates the prevalence of self-reported skin problems among Latino farmworkers and identifies associated risk factors... - The association of dermatologist-diagnosed and self-reported skin diseases with skin-related quality of life in Latino migrant farmworkersSara A Quandt
Division of Public Health Sciences, Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Int J Dermatol 47:236-41. 2008..Farmworkers are at high risk for skin diseases, and are an appropriate population in which to explore these associations... - UV light abuse as a substance-related disorder: clinical implicationsStephen B W Keen
Department of Dermatology, Wake Forest School of Medicine, Medical Center Blvd, Box 2514, Winston-Salem, NC 27157-1071, USA
Arch Dermatol 144:1047-8. 2008 - The relationship between cognitive function and physical performance in older women: results from the women's health initiative memory studyHal H Atkinson
Wake Forest University School of Medicine, Sticht Center on Aging, Roena Kulynych Center for Memory and Cognition Research, and Department of Internal Medicine Gerontology and Geriatric Medicine, Winston Salem, North Carolina 27157, USA
J Gerontol A Biol Sci Med Sci 65:300-6. 2010..Cognitive function and physical performance are associated, but the common sequence of cognitive and physical decline remains unclear... - Postmenopausal hormone therapy and cognitive outcomes: the Women's Health Initiative Memory Study (WHIMS)Laura H Coker
Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Steroid Biochem Mol Biol 118:304-10. 2010..05); frontal lobe (P=0.004); and total brain (P=0.07). HT-associated reductions in hippocampal volumes were greatest in women with baseline 3MS scores < or = 90... - Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognitionMark A Espeland
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Womens Health (Larchmt) 19:371-9. 2010..To compare the relative effects of conjugated equine estrogens (CEE), raloxifene, and tamoxifen therapies on cognition among women aged > or =65 years... - Phase II study of donepezil in irradiated brain tumor patients: effect on cognitive function, mood, and quality of lifeEdward G Shaw
Department of Radiation Oncology, Wake Forest University School of Medicine, Brain Tumor Center of Excellence of WFU, Winston Salem, NC 27157 1030, USA
J Clin Oncol 24:1415-20. 2006.... - Association between reported alcohol intake and cognition: results from the Women's Health Initiative Memory StudyMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Am J Epidemiol 161:228-38. 2005..Moderate levels of alcohol intake may be associated with better cognition and reduced risk of significant cognitive decline; however, confounding associations with unmeasured factors cannot be ruled out... - Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trialSally A Shumaker
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27104, USA
JAMA 289:2651-62. 2003..On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's Health Initiative (WHI) trial were discontinued because of certain increased health risks in women receiving combined hormone therapy... - Do optimism and pessimism predict physical functioning?Gretchen A Brenes
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1063, USA
J Behav Med 25:219-31. 2002..001), while optimism was related to performance only on the walking task (p < .05), after controlling for demographic and health variables... - Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory StudySally A Shumaker
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 291:2947-58. 2004..The Women's Health Initiative Memory Study (WHIMS) previously found increased risk for dementia and no effect on mild cognitive impairment (MCI) in women treated with conjugated equine estrogens (CEE) plus medroxyprogesterone acetate (MPA)... - Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory StudyMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 291:2959-68. 2004..The effect of estrogen-alone therapy, also evaluated in WHIMS, on cognition has not been established for this population... - The family impact of atopic dermatitis in children: the role of the parent caregiverRajesh Balkrishnan
Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Pediatr Dermatol 20:5-10. 2003..These parent caregiver factors may be important in identifying suitable audiences and areas for education for optimal management of children's AD... - Ultraviolet exposure is a reinforcing stimulus in frequent indoor tannersSteven R Feldman
Department of Dermatology, Wake Forest University Health Sciences, USA
J Am Acad Dermatol 51:45-51. 2004..Investigations into tanners' reasons for tanning have focused primarily on the perception of improved appearance. Reported relaxing effects of tanning suggest the possibility of a physiologic effect of UV that drives tanning behavior... - A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapyJerome M Butler
Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Int J Radiat Oncol Biol Phys 69:1496-501. 2007..We assessed the effect of prophylactic d-threo-methylphenidate HCl (d-MPH), a central nervous system (CNS) stimulant on QOL and cognitive function in patients undergoing RT... - Correlates of health-related quality of life in women with severe facial blemishesRajesh Balkrishnan
Department of Dermatology, Psychiatry, and Public Health Services, Wake Forest University School of Medicine, Winston Salem, NC, USA
Int J Dermatol 45:111-5. 2006..Visible facial skin lesions are a common condition. Purpose This study assessed factors associated with health-related quality of life (HRQOL) in women with visible facial skin lesions... - Induction of withdrawal-like symptoms in a small randomized, controlled trial of opioid blockade in frequent tannersMandeep Kaur
Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1071, USA
J Am Acad Dermatol 54:709-11. 2006..Opioid blockade reduced ultraviolet preference in frequent tanners. Four of 8 frequent tanners, but no infrequent tanners, exhibited withdrawal-like symptoms with naltrexone administration. A limitation of this study is its small size... - Managing the cognitive effects of brain tumor radiation therapyJerome M Butler
Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA
Curr Treat Options Oncol 7:517-23. 2006..Given the prevalence of brain neoplasms and the high incidence of the radiation-induced symptom cluster and brain injury, clinical research to address these important clinical problems is critical... - Social sensitivity and acne: the role of personality in negative social consequences and quality of lifeJennifer Krejci-Manwaring
Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
Int J Psychiatry Med 36:121-30. 2006..Dispositional social sensitivity is an independent psychological factor associated with poorer social functioning and quality of life. Treatment of the acne patient should consider psychosocial factors as well as biological factors... - Patients with psoriasis prefer solution and foam vehicles: a quantitative assessment of vehicle preferenceTamara Salam Housman
Department of Dermatology, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA
Cutis 70:327-32. 2002..Although validated measures of adherence to topical therapy are not yet available, the results of this study suggest that the characteristics of solution and foam may favor improved adherence to topical therapy... - Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: implications for clinical practiceAdam A Pettey
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC 27104, USA
J Am Acad Dermatol 49:271-5. 2003..CONCLUSION: Patients with palmoplantar psoriasis are affected to a greater degree by the physical aspects of the disease than patients without palmoplantar involvement... - Spanish dermatological vocabulary used by Mexican workersQuirina M Vallejos
Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Dermatol Online J 11:32. 2005..This glossary is a supplement to other resources for learning medical Spanish and expands health care professionals' knowledge of dermatology-related Spanish vocabulary... - What predicts patients' expressed likelihood of choosing electroconvulsive therapy as a future treatment option?Peter B Rosenquist
Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157 1087, USA
J ECT 22:33-7. 2006.... - Women's cognitive health: postmenopausal dementia and the women's health initiative memory studyKaren Potvin Klein
Womens Health Issues 14:71-4. 2004 - Effects of combination estrogen plus progestin hormone treatment on cognition and affectSusan M Resnick
National Institute on Aging, Baltimore, Maryland 21224 6825, USA
J Clin Endocrinol Metab 91:1802-10. 2006..Some studies of hormone treatment in postmenopausal women suggest benefits on specific cognitive functions, particularly memory... - The Women's Health Initiative Study of Cognitive Aging (WHISCA): a randomized clinical trial of the effects of hormone therapy on age-associated cognitive declineSusan M Resnick
Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, Maryland 21224 6825, USA
Clin Trials 1:440-50. 2004.... - Effects of conjugated equine estrogen on stroke in the Women's Health InitiativeSusan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine Hutzel Women s Hospital, Detroit, MI, USA
Circulation 113:2425-34. 2006..This report provides a thorough analysis of the stroke finding using the final results from the completed trial database... - Measurement of health-related quality of life (HRQOL) associated with skin diseaseRajesh Balkrishnan
University of Texas School of Public Health, Houston, TX, USA
J Am Acad Dermatol 51:S3-4. 2004
Research Grants
- Phase III Study of Donepezil in the Irradiated BrainStephen Rapp; Fiscal Year: 2007..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..
- Phase III Study of Donepezil in the Irradiated BrainStephen Rapp; Fiscal Year: 2009..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..
- Phase III Study of Donepezil in the Irradiated BrainStephen R Rapp; Fiscal Year: 2010..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..