Stephen Rapp

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Social coping strategies associated with quality of life decrements among psoriasis patients
    S R Rapp
    Department of Psychiatry, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Br J Dermatol 145:610-6. 2001
  2. ncbi request reprint The promise and challenge of new biological treatments for psoriasis: how do they impact quality of life?
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Dermatol Ther 17:376-82. 2004
  3. ncbi request reprint The Acne Quality of Life Index (Acne-QOLI): development and validation of a brief instrument
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am J Clin Dermatol 7:185-92. 2006
  4. ncbi request reprint Baseline experience with Modified Mini Mental State Exam: The Women's Health Initiative Memory Study (WHIMS)
    S R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Aging Ment Health 7:217-23. 2003
  5. ncbi request reprint Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 289:2663-72. 2003
  6. ncbi request reprint Memory enhancement training for older adults with mild cognitive impairment: a preliminary study
    S Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Wake Forest University 27157, USA
    Aging Ment Health 6:5-11. 2002
  7. pmc Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: the Seniors Health and Activity Research Program Pilot (SHARP-P) study, a randomized controlled trial
    Claudine Legault
    Division of Public Health Sciences, Department of Biostatistical Sciences Wachovia 21st floor, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    BMC Geriatr 11:27. 2011
  8. pmc Long-term effects of conjugated equine estrogen therapies on domain-specific cognitive function: results from the Women's Health Initiative study of cognitive aging extension
    Mark A Espeland
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    J Am Geriatr Soc 58:1263-71. 2010
  9. doi request reprint Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) study
    Mark A Espeland
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
    Int J Geriatr Psychiatry 26:135-43. 2011
  10. ncbi request reprint Benchmarks for designing two-stage studies using modified mini-mental state examinations: experience from the Women's Health Initiative Memory Study
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Clin Trials 3:99-106. 2006

Research Grants

Detail Information

Publications41

  1. ncbi request reprint Social coping strategies associated with quality of life decrements among psoriasis patients
    S R Rapp
    Department of Psychiatry, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Br J Dermatol 145:610-6. 2001
    ..Individuals with psoriasis often report significant psychological distress, physical disability, social strain and reduced quality of life. Little is known about how they cope with the illness...
  2. ncbi request reprint The promise and challenge of new biological treatments for psoriasis: how do they impact quality of life?
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Dermatol Ther 17:376-82. 2004
    ..These measures have been used to show the benefits new biologic medications offer our patients...
  3. ncbi request reprint The Acne Quality of Life Index (Acne-QOLI): development and validation of a brief instrument
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am J Clin Dermatol 7:185-92. 2006
    ..Assessing the impact of acne on quality of life requires well-validated and reliable measures of acne-specific quality of life that are brief and easy to administer and interpret...
  4. ncbi request reprint Baseline experience with Modified Mini Mental State Exam: The Women's Health Initiative Memory Study (WHIMS)
    S R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Aging Ment Health 7:217-23. 2003
    ..Despite relatively narrow distributions in WHIMS, baseline 3MS scores retained associations with age and education. These associations varied among ethnic groups, so that care must be taken in comparing data across populations...
  5. ncbi request reprint Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial
    Stephen R Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 289:2663-72. 2003
    ..On July 8, 2002, the estrogen plus progestin therapy in the WHI trial was discontinued because of certain increased health risks for women...
  6. ncbi request reprint Memory enhancement training for older adults with mild cognitive impairment: a preliminary study
    S Rapp
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Wake Forest University 27157, USA
    Aging Ment Health 6:5-11. 2002
    ..Findings suggest that individuals with MCI can benefit from multi-component memory enhancement training. Further development of such training programs and tests of their efficacy alone and in combination with medications are needed...
  7. pmc Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: the Seniors Health and Activity Research Program Pilot (SHARP-P) study, a randomized controlled trial
    Claudine Legault
    Division of Public Health Sciences, Department of Biostatistical Sciences Wachovia 21st floor, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    BMC Geriatr 11:27. 2011
    ..Before definitive trials are mounted, important design questions on participation/adherence, training and interventions effects must be answered to more fully inform a full-scale trial...
  8. pmc Long-term effects of conjugated equine estrogen therapies on domain-specific cognitive function: results from the Women's Health Initiative study of cognitive aging extension
    Mark A Espeland
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    J Am Geriatr Soc 58:1263-71. 2010
    ..To determine whether small decrements in global cognitive function that conjugated equine estrogen (CEE) therapies have been shown to produce in older women persist after cessation and extend to specific cognitive domains...
  9. doi request reprint Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) study
    Mark A Espeland
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
    Int J Geriatr Psychiatry 26:135-43. 2011
    ..To examine the performance of the Telephone Interview for Cognitive Status (TICS) for identifying participants appropriate for trials of physical activity and cognitive training interventions...
  10. ncbi request reprint Benchmarks for designing two-stage studies using modified mini-mental state examinations: experience from the Women's Health Initiative Memory Study
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Clin Trials 3:99-106. 2006
    ..The modified mini-mental state examination (3MS) is commonly used as this initial screen in such two-stage designs, however its properties for this role require further study...
  11. ncbi request reprint Association between alcohol intake and domain-specific cognitive function in older women
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Neuroepidemiology 27:1-12. 2006
    ..However, our observational study cannot rule out confounding associations with unmeasured factors...
  12. ncbi request reprint Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study
    Hal H Atkinson
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 62:844-50. 2007
    ..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults...
  13. ncbi request reprint Symptom clusters in patients with newly-diagnosed brain tumors
    John F Gleason
    Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Support Oncol 5:427-33, 436. 2007
    ..Our results suggest that interventions that target both cognitive function and mood should be considered in this patient population. Further research on symptom clusters in brain tumor patients is needed...
  14. doi request reprint Self report of skin problems among farmworkers in North Carolina
    Quirina M Vallejos
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1084, USA
    Am J Ind Med 51:204-12. 2008
    ..This study estimates the prevalence of self-reported skin problems among Latino farmworkers and identifies associated risk factors...
  15. doi request reprint The association of dermatologist-diagnosed and self-reported skin diseases with skin-related quality of life in Latino migrant farmworkers
    Sara A Quandt
    Division of Public Health Sciences, Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Int J Dermatol 47:236-41. 2008
    ..Farmworkers are at high risk for skin diseases, and are an appropriate population in which to explore these associations...
  16. doi request reprint UV light abuse as a substance-related disorder: clinical implications
    Stephen B W Keen
    Department of Dermatology, Wake Forest School of Medicine, Medical Center Blvd, Box 2514, Winston Salem, NC 27157 1071, USA
    Arch Dermatol 144:1047-8. 2008
  17. pmc The relationship between cognitive function and physical performance in older women: results from the women's health initiative memory study
    Hal H Atkinson
    Wake Forest University School of Medicine, Sticht Center on Aging, Roena Kulynych Center for Memory and Cognition Research, and Department of Internal Medicine Gerontology and Geriatric Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 65:300-6. 2010
    ..Cognitive function and physical performance are associated, but the common sequence of cognitive and physical decline remains unclear...
  18. doi request reprint Postmenopausal hormone therapy and cognitive outcomes: the Women's Health Initiative Memory Study (WHIMS)
    Laura H Coker
    Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    J Steroid Biochem Mol Biol 118:304-10. 2010
    ..05); frontal lobe (P=0.004); and total brain (P=0.07). HT-associated reductions in hippocampal volumes were greatest in women with baseline 3MS scores < or = 90...
  19. pmc Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition
    Mark A Espeland
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Womens Health (Larchmt) 19:371-9. 2010
    ..To compare the relative effects of conjugated equine estrogens (CEE), raloxifene, and tamoxifen therapies on cognition among women aged > or =65 years...
  20. ncbi request reprint Phase II study of donepezil in irradiated brain tumor patients: effect on cognitive function, mood, and quality of life
    Edward G Shaw
    Department of Radiation Oncology, Wake Forest University School of Medicine, Brain Tumor Center of Excellence of WFU, Winston Salem, NC 27157 1030, USA
    J Clin Oncol 24:1415-20. 2006
    ....
  21. ncbi request reprint Association between reported alcohol intake and cognition: results from the Women's Health Initiative Memory Study
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am J Epidemiol 161:228-38. 2005
    ..Moderate levels of alcohol intake may be associated with better cognition and reduced risk of significant cognitive decline; however, confounding associations with unmeasured factors cannot be ruled out...
  22. ncbi request reprint Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial
    Sally A Shumaker
    Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27104, USA
    JAMA 289:2651-62. 2003
    ..On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's Health Initiative (WHI) trial were discontinued because of certain increased health risks in women receiving combined hormone therapy...
  23. ncbi request reprint Do optimism and pessimism predict physical functioning?
    Gretchen A Brenes
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1063, USA
    J Behav Med 25:219-31. 2002
    ..001), while optimism was related to performance only on the walking task (p < .05), after controlling for demographic and health variables...
  24. ncbi request reprint Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study
    Sally A Shumaker
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 291:2947-58. 2004
    ..The Women's Health Initiative Memory Study (WHIMS) previously found increased risk for dementia and no effect on mild cognitive impairment (MCI) in women treated with conjugated equine estrogens (CEE) plus medroxyprogesterone acetate (MPA)...
  25. ncbi request reprint Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study
    Mark A Espeland
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 291:2959-68. 2004
    ..The effect of estrogen-alone therapy, also evaluated in WHIMS, on cognition has not been established for this population...
  26. ncbi request reprint The family impact of atopic dermatitis in children: the role of the parent caregiver
    Rajesh Balkrishnan
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Pediatr Dermatol 20:5-10. 2003
    ..These parent caregiver factors may be important in identifying suitable audiences and areas for education for optimal management of children's AD...
  27. ncbi request reprint Ultraviolet exposure is a reinforcing stimulus in frequent indoor tanners
    Steven R Feldman
    Department of Dermatology, Wake Forest University Health Sciences, USA
    J Am Acad Dermatol 51:45-51. 2004
    ..Investigations into tanners' reasons for tanning have focused primarily on the perception of improved appearance. Reported relaxing effects of tanning suggest the possibility of a physiologic effect of UV that drives tanning behavior...
  28. ncbi request reprint A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy
    Jerome M Butler
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Int J Radiat Oncol Biol Phys 69:1496-501. 2007
    ..We assessed the effect of prophylactic d-threo-methylphenidate HCl (d-MPH), a central nervous system (CNS) stimulant on QOL and cognitive function in patients undergoing RT...
  29. ncbi request reprint Correlates of health-related quality of life in women with severe facial blemishes
    Rajesh Balkrishnan
    Department of Dermatology, Psychiatry, and Public Health Services, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Int J Dermatol 45:111-5. 2006
    ..Visible facial skin lesions are a common condition. Purpose This study assessed factors associated with health-related quality of life (HRQOL) in women with visible facial skin lesions...
  30. ncbi request reprint Induction of withdrawal-like symptoms in a small randomized, controlled trial of opioid blockade in frequent tanners
    Mandeep Kaur
    Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1071, USA
    J Am Acad Dermatol 54:709-11. 2006
    ..Opioid blockade reduced ultraviolet preference in frequent tanners. Four of 8 frequent tanners, but no infrequent tanners, exhibited withdrawal-like symptoms with naltrexone administration. A limitation of this study is its small size...
  31. ncbi request reprint Managing the cognitive effects of brain tumor radiation therapy
    Jerome M Butler
    Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Curr Treat Options Oncol 7:517-23. 2006
    ..Given the prevalence of brain neoplasms and the high incidence of the radiation-induced symptom cluster and brain injury, clinical research to address these important clinical problems is critical...
  32. ncbi request reprint Social sensitivity and acne: the role of personality in negative social consequences and quality of life
    Jennifer Krejci-Manwaring
    Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Int J Psychiatry Med 36:121-30. 2006
    ..The adverse social impact of acne is well documented. Negative social consequences, however, are likely to be determined by personality features as well as acne severity...
  33. ncbi request reprint Patients with psoriasis prefer solution and foam vehicles: a quantitative assessment of vehicle preference
    Tamara Salam Housman
    Department of Dermatology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Cutis 70:327-32. 2002
    ..Although validated measures of adherence to topical therapy are not yet available, the results of this study suggest that the characteristics of solution and foam may favor improved adherence to topical therapy...
  34. ncbi request reprint Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: implications for clinical practice
    Adam A Pettey
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, NC 27104, USA
    J Am Acad Dermatol 49:271-5. 2003
    ..Psoriasis is a chronic, unpredictable, and incurable disease that has a negative impact on patients' quality of life. Palm and sole psoriasis can add to this negative impact as it directly affects activities of daily living...
  35. ncbi request reprint Spanish dermatological vocabulary used by Mexican workers
    Quirina M Vallejos
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Dermatol Online J 11:32. 2005
    ..This glossary is a supplement to other resources for learning medical Spanish and expands health care professionals' knowledge of dermatology-related Spanish vocabulary...
  36. ncbi request reprint What predicts patients' expressed likelihood of choosing electroconvulsive therapy as a future treatment option?
    Peter B Rosenquist
    Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157 1087, USA
    J ECT 22:33-7. 2006
    ....
  37. ncbi request reprint Women's cognitive health: postmenopausal dementia and the women's health initiative memory study
    Karen Potvin Klein
    Womens Health Issues 14:71-4. 2004
  38. ncbi request reprint Effects of combination estrogen plus progestin hormone treatment on cognition and affect
    Susan M Resnick
    National Institute on Aging, Baltimore, Maryland 21224 6825, USA
    J Clin Endocrinol Metab 91:1802-10. 2006
    ..Some studies of hormone treatment in postmenopausal women suggest benefits on specific cognitive functions, particularly memory...
  39. ncbi request reprint The Women's Health Initiative Study of Cognitive Aging (WHISCA): a randomized clinical trial of the effects of hormone therapy on age-associated cognitive decline
    Susan M Resnick
    Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, Maryland 21224 6825, USA
    Clin Trials 1:440-50. 2004
    ....
  40. ncbi request reprint Effects of conjugated equine estrogen on stroke in the Women's Health Initiative
    Susan L Hendrix
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine Hutzel Women s Hospital, Detroit, MI, USA
    Circulation 113:2425-34. 2006
    ..This report provides a thorough analysis of the stroke finding using the final results from the completed trial database...
  41. ncbi request reprint Measurement of health-related quality of life (HRQOL) associated with skin disease
    Rajesh Balkrishnan
    University of Texas School of Public Health, Houston, TX, USA
    J Am Acad Dermatol 51:S3-4. 2004

Research Grants4

  1. Phase III Study of Donepezil in the Irradiated Brain
    Stephen Rapp; Fiscal Year: 2007
    ..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..
  2. Phase III Study of Donepezil in the Irradiated Brain
    Stephen Rapp; Fiscal Year: 2009
    ..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..
  3. Phase III Study of Donepezil in the Irradiated Brain
    Stephen R Rapp; Fiscal Year: 2010
    ..If successful the study will offer physicians a treatment for radiation-induced cognitive impairment which also may improve mood and quality of life. ..