Graziano Onder

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. doi request reprint Polypharmacy in nursing home in Europe: results from the SHELTER study
    Graziano Onder
    Centro Medicina dell Invecchiamento, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Largo F Vito 1, 00168, Roma, Italy
    J Gerontol A Biol Sci Med Sci 67:698-704. 2012
  2. ncbi request reprint Trends in antihypertensive drugs in the elderly: the decline of thiazides
    G Onder
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Hum Hypertens 15:291-7. 2001
  3. ncbi request reprint Treatment of osteoporosis among older adults discharged from hospital in Italy
    G Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Medical Center Boulevard Winston Salem, NC 27157, USA
    Eur J Clin Pharmacol 57:599-604. 2001
  4. ncbi request reprint Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study
    Graziano Onder
    Sticht Center on Aging, Section on Gerontology and Geriatrics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Lancet 359:926-30. 2002
  5. ncbi request reprint Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Stricht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Pharmacotherapy 23:240-7. 2003
  6. ncbi request reprint Moderate alcohol consumption and adverse drug reactions among older adults
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Winston Salem, NC, USA
    Pharmacoepidemiol Drug Saf 11:385-92. 2002
  7. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
  8. ncbi request reprint Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    J Clin Epidemiol 60:518-24. 2007
  9. doi request reprint Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Eur J Nutr 52:1261-8. 2013
  10. ncbi request reprint Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    Francesco Landi
    Department of Gerontology Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:622-6. 2005

Detail Information

Publications98

  1. doi request reprint Polypharmacy in nursing home in Europe: results from the SHELTER study
    Graziano Onder
    Centro Medicina dell Invecchiamento, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Largo F Vito 1, 00168, Roma, Italy
    J Gerontol A Biol Sci Med Sci 67:698-704. 2012
    ..This study assesses prevalence and patients characteristics related to polypharmacy in a sample of nursing home residents...
  2. ncbi request reprint Trends in antihypertensive drugs in the elderly: the decline of thiazides
    G Onder
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Hum Hypertens 15:291-7. 2001
    ..A possible explanation is that the choice to prescribe a thiazides diuretic is influenced by age, functional status and comorbidity...
  3. ncbi request reprint Treatment of osteoporosis among older adults discharged from hospital in Italy
    G Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Medical Center Boulevard Winston Salem, NC 27157, USA
    Eur J Clin Pharmacol 57:599-604. 2001
    ....
  4. ncbi request reprint Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study
    Graziano Onder
    Sticht Center on Aging, Section on Gerontology and Geriatrics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Lancet 359:926-30. 2002
    ..We aimed to see whether ACE inhibitors also prevent reduction in physical performance and in muscle strength in older women who do not have CHF...
  5. ncbi request reprint Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Stricht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Pharmacotherapy 23:240-7. 2003
    ..To evaluate whether hospitalization affects blood pressure control in hypertensive patients, and to identify factors associated with attainment of adequate blood pressure control and with aggressive pharmacologic treatment...
  6. ncbi request reprint Moderate alcohol consumption and adverse drug reactions among older adults
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Winston Salem, NC, USA
    Pharmacoepidemiol Drug Saf 11:385-92. 2002
    ..To assess the effect of moderate alcohol consumption on Adverse Drug Reactions (ADRs) among older adults admitted to acute care hospitals and to examine the consistency of this effect across gender and age groups...
  7. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
    ..Physical function measures have gained increased importance in the evaluation of older persons. The presence of comorbidity is a major and growing issue in geriatrics...
  8. ncbi request reprint Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    J Clin Epidemiol 60:518-24. 2007
    ..The aims of the study were to describe the prevalence of physical activity in a sample of older adults in home care in Europe and to examine the relationship between physical activity and incident disability...
  9. doi request reprint Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Eur J Nutr 52:1261-8. 2013
    ..There is increasing evidence that anorexia of aging can cause physical and mental impairment. The aim of the present study was to evaluate the relationship between anorexia and sarcopenia in elderly persons aged 80 years or older...
  10. ncbi request reprint Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    Francesco Landi
    Department of Gerontology Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:622-6. 2005
    ..Although a small number of falls have a single cause, the majority have many different causes resulting from the interactions between intrinsic or extrinsic risk factors...
  11. ncbi request reprint Depression and adverse drug reactions among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168 Rome, Italy
    Arch Intern Med 163:301-5. 2003
    ..The aim of this study was to assess whether depression may be a risk factor for adverse drug reactions (ADRs) among hospitalized older adults...
  12. ncbi request reprint The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Aging Clin Exp Res 17:486-93. 2005
    ....
  13. doi request reprint Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Age Ageing 42:203-9. 2013
    ..32, 95% CI: 1.01-5.43). Conclusions: our results obtained from a representative sample of very old and frail subjects show that sarcopenia is associated with mortality, independently of age and other clinical and functional variables...
  14. ncbi request reprint The effects of cognitive impairment on mortality among hospitalized patients with heart failure
    Giuseppe Zuccala
    Department of Gerontology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Med 115:97-103. 2003
    ..Because cerebral metabolic abnormalities have been associated with reduced survival in younger patients with advanced heart failure, we assessed the effect of cognitive impairment on the survival of older patients with heart failure...
  15. pmc All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study
    Rosa Liperoti
    Centro di Medicina dell Invecchiamento, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Largo A Gemelli, 8 0168 Rome, Italy
    J Clin Psychiatry 70:1340-7. 2009
    ..We conducted a retrospective cohort study to compare the risk of death associated with atypical and conventional antipsychotics in a large population of nursing home residents with dementia...
  16. ncbi request reprint Depression and risk of nursing home admission among older adults in home care in Europe: results from the Aged in Home Care (AdHOC) study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    J Clin Psychiatry 68:1392-8. 2007
    ..The aim of the present study was to assess the effect of depression on the risk of nursing home admission in a group of older adults receiving home care in Europe...
  17. ncbi request reprint Total serum cholesterol and recovery from disability among hospitalized older adults
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 61:736-42. 2006
    ..The objective of the present study was to determine within a cohort of acutely hospitalized disabled elderly patients whether total cholesterol predicts recovery from disability in basic activities of daily living (ADL)...
  18. doi request reprint Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Clin Epidemiol 63:752-9. 2010
    ..In this study, we evaluate the impact of disability and multimorbidity on the risk of all-cause death in a population of frail older persons living in community...
  19. ncbi request reprint Association between pain and depression among older adults in Europe: results from the Aged in Home Care (AdHOC) project: a cross-sectional study
    Graziano Onder
    Department of Gerontologic Science, Catholic University of the Sacred Heart, Rome, Italy
    J Clin Psychiatry 66:982-8. 2005
    ..To assess the association between pain and depression in a population of older adults...
  20. ncbi request reprint Impact of inappropriate drug use on physical performance among a frail elderly population living in the community
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:791-9. 2007
    ..The aim of the present study was to evaluate the relationship between the use of inappropriate drugs and measures of physical performance, muscle strength and functional status in an elderly population (80+ years)...
  21. doi request reprint Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica Sacro Cuore, Rome, Italy
    J Am Med Dir Assoc 14:450.e7-12. 2013
    ..The aim of the present study was to assess if, in a sample of nursing home (NH) residents with advanced cognitive impairment, the effect of polypharmacy on mortality differs depending on estimated life expectancy...
  22. doi request reprint Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individuals
    Silvia Giovannini
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 59:1679-85. 2011
    ..To investigate whether interleukin-6 (IL-6), C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-α) protein levels predict all-cause mortality in older persons living in the community...
  23. ncbi request reprint Comorbidity and social factors predicted hospitalization in frail elderly patients
    Francesco Landi
    Instituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Clin Epidemiol 57:832-6. 2004
    ....
  24. ncbi request reprint Indwelling urethral catheter and mortality in frail elderly women living in community
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Neurourol Urodyn 23:697-701. 2004
    ..The aims of present study were to describe the prevalence of bladder catheter in a population of older women living in community and to examine the relationship between urinary catheter and mortality...
  25. doi request reprint Metacognitive unawareness correlates with executive function impairment after severe traumatic brain injury
    Paola Ciurli
    Post Coma Unit, Santa Lucia Foundation, Rome, Italy
    J Int Neuropsychol Soc 16:360-8. 2010
    ..This study suggests the importance of integrating an overall assessment of cognitive functions with a specific evaluation of SA to treat self-awareness and executive functions together during the rehabilitation process...
  26. pmc Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study
    Matteo Cesari
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Roma, Italy
    BMC Geriatr 8:34. 2008
    ..Aim of the present study is to compare the predictive value for mortality of measures of physical function and SRH status, and test their possible interactions...
  27. ncbi request reprint Anemia is associated with depression in older adults: results from the InCHIANTI study
    Graziano Onder
    Geriatric Department, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:1168-72. 2005
    ..The objective of this study was to examine whether depressive symptoms and anemia are associated among older adults living in the community...
  28. doi request reprint Myeloperoxidase levels and mortality in frail community-living elderly individuals
    Silvia Giovannini
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 65:369-76. 2010
    ....
  29. ncbi request reprint Association between daily pain and physical function among old-old adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    Pain 121:53-9. 2006
    ..In conclusion, the present study shows that among old-old subjects living in the community, daily pain is highly prevalent and that this condition is associated with impaired muscle strength and physical performance...
  30. ncbi request reprint Body mass index, free insulin-like growth factor I, and physical function among older adults: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Am J Physiol Endocrinol Metab 291:E829-34. 2006
    ..By contrast, no association was observed between IGFBP-3 and study outcomes, independently of BMI. In conclusion, high IGF-I level is associated with better physical function in older persons with obesity, but not in nonobese subjects...
  31. ncbi request reprint Anemia and cognitive performance in hospitalized older patients: results from the GIFA study
    Valentina Zamboni
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Int J Geriatr Psychiatry 21:529-34. 2006
    ..Anemia represents a major risk factor for adverse health-related events in older persons. The aim of this study was to evaluate the association between hemoglobin levels/anemia and cognitive function in hospitalized older persons...
  32. ncbi request reprint Impact of inappropriate drug use among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 61:453-9. 2005
    ..The objective of this study was to evaluate the impact of inappropriate drug use on all-cause mortality, adverse drug reactions (ADRs) and length of stay among in-hospital patients...
  33. ncbi request reprint Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study
    Mauro Di Bari
    Department of Internal Medicine, Sticht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:961-6. 2004
    ..To evaluate whether older persons using angiotensin-converting enzyme (ACE) inhibitors have a larger lower extremity muscle mass (LEMM) than users of other antihypertensive drugs...
  34. ncbi request reprint Case management and risk of nursing home admission for older adults in home care: results of the AgeD in HOme Care Study
    Graziano Onder
    Department of Gerontology, Catholic University Sacred Heart, Rome, Italy
    J Am Geriatr Soc 55:439-44. 2007
    ..To explore the relationship between a case management approach and the risk of institutionalization in a large European population of frail, old people in home care...
  35. ncbi request reprint Anemia and decline in physical performance among older persons
    Brenda W J H Penninx
    Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Am J Med 115:104-10. 2003
    ..We examined whether anemia in older persons increases the risk of subsequent decline in physical function, as measured by objective performance-based tests...
  36. ncbi request reprint Physical activity and risk of cognitive impairment among older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 19:410-6. 2007
    ..The aim of the present study was to evaluate the relationship of lifetime physical activity with cognitive performance in older persons aged 80 years or older...
  37. doi request reprint Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of the Sacred Heart, Rome, Italy
    J Pain Symptom Manage 38:350-7. 2009
    ..94; 95% CI: 2.00-23.01). In conclusion, among very old subjects living in the community, moderate to severe daily pain is associated with a significant increased risk of disability, irrespective of potential confounders...
  38. ncbi request reprint Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 59:157-62. 2003
    ..To determine the prevalence of inappropriate medication use among hospitalized older adults and to identify predictors of this use...
  39. ncbi request reprint Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 54:71-8. 2008
    ..High-density lipoprotein (HDL) cholesterol has been hypothesized to be a reliable marker of frailty and poor prognosis among the oldest elderly...
  40. ncbi request reprint Serum cholesterol levels and in-hospital mortality in the elderly
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Am J Med 115:265-71. 2003
    ..We explored whether total cholesterol levels were independently associated with in-hospital mortality among elderly patients...
  41. pmc Assessment of nursing home residents in Europe: the Services and Health for Elderly in Long TERm care (SHELTER) study
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica Sacro Cuore, Rome, Italy
    BMC Health Serv Res 12:5. 2012
    ..to present the results about the test-retest and inter-rater reliability of the interRAI LTCF instrument translated into the languages of participating countries; 3 to illustrate the characteristics of NH residents at study entry...
  42. ncbi request reprint Use of calcium antagonists and worsening renal function in patients receiving angiotensin-converting-enzyme inhibitors
    Giuseppe Zuccala
    Catholic University of the Sacred Heart, L go F Vito 1, 00168, Rome, Italy
    Eur J Clin Pharmacol 58:695-9. 2003
    ....
  43. ncbi request reprint Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 50:1962-8. 2002
    ....
  44. ncbi request reprint Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:389-95. 2007
    ..However, this relationship has only rarely been investigated in humans. The aim of the present cross-sectional study was to assess the association of ACE inhibitors with free IGF-1 and IGFBP-3 in the blood of older hypertensive adults...
  45. doi request reprint Polypharmacy in nursing home residents with severe cognitive impairment: results from the SHELTER Study
    Davide L Vetrano
    Centro Medicina dell Invecchiamento, Universita Cattolica Sacro Cuore, Rome, Italy
    Alzheimers Dement 9:587-93. 2013
    ..The aim of the current study is to assess prevalence and factors related to polypharmacy in a sample of nursing home (nursing home) residents with advanced cognitive impairment...
  46. pmc Inappropriate drugs in elderly patients with severe cognitive impairment: results from the shelter study
    Giuseppe Colloca
    Centro Medicina dell Invecchiamento, Universita Cattolica Sacro Cuore, Rome, Italy
    PLoS ONE 7:e46669. 2012
    ..The aim of this study was to determine prevalence and factors associated with use of inappropriate drugs in elderly patients with severe cognitive impairment living in NH in Europe...
  47. doi request reprint Interaction between GSTM1 genotype and IL-6 on mortality in older adults: results from the ilSIRENTE study
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Cytokine 53:301-5. 2011
    ..The aim of the present study was to assess if, in a population of older adults, the effect of antioxidant genes GSTM1 and GSTT1 genotypes on mortality may differ depending on levels of inflammation...
  48. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and Alzheimer disease in community-dwelling elderly patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Am J Geriatr Psychiatry 11:179-85. 2003
    ..The aim of the present study was to examine the relationship between NSAIDs use and AD in a large sample of community-dwelling elderly people...
  49. ncbi request reprint Chewing problems and mortality in older adults in home care: results from the Aged in Home Care study
    Graziano Onder
    Department of Gerontology, Catholic University Sacred Heart, Rome, Italy
    J Am Geriatr Soc 55:1961-6. 2007
    ..To assess the association between chewing problems and risk of mortality in an older population receiving home care in Europe...
  50. ncbi request reprint Hemoglobin levels and skeletal muscle: results from the InCHIANTI study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Gerontol A Biol Sci Med Sci 59:249-54. 2004
    ..Anemia is associated with reduced physical performance and muscle strength. The aim of the study was to explore whether anemia and hemoglobin levels are associated with differences in quantitative and qualitative measures of muscle and fat...
  51. ncbi request reprint Prevalence and predictors of influenza vaccination among frail, community-living elderly patients: an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    Vaccine 23:3896-901. 2005
    ..In conclusion, more than 40% of subjects in this sample of home care patients in Europe did not receive influenza vaccination. Recommendations for influenza vaccination have not been adequately implemented...
  52. ncbi request reprint Pattern of medication use among older inpatients in seven hospitals in Italy: results from the CRiteria to assess Appropriate Medication use among Elderly complex patients (CRIME) project
    Matteo Tosato
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Curr Drug Saf 8:98-103. 2013
    ..Patterns of drugs use have rarely been investigated in these patients...
  53. ncbi request reprint Second and third generation assessment instruments: the birth of standardization in geriatric care
    Roberto Bernabei
    Centro Medicina dell Invecchiamento CEMI, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Gerontol A Biol Sci Med Sci 63:308-13. 2008
    ....
  54. ncbi request reprint Benzodiazepines and the risk of urinary incontinence in frail older persons living in the community
    Francesco Landi
    Department of Gerontology Geriatrics and Physiatrics, Catholic University of Sacred Heart, Rome, Italy
    Clin Pharmacol Ther 72:729-34. 2002
    ..The aim of this study was to estimate the risk of urinary incontinence associated with the use of oxidative or nonoxidative benzodiazepines...
  55. ncbi request reprint Pain and its relation to depressive symptoms in frail older people living in the community: an observational study
    Francesco Landi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Pain Symptom Manage 29:255-62. 2005
    ..Treatment models that put together the assessment and the treatment of both pain and depression are indispensable for better outcomes...
  56. doi request reprint Prevalence of the seven cardiovascular health metrics in a Mediterranean country: results from a cross-sectional study
    Davide Liborio Vetrano
    Department of Gerontology, Neuroscience and Orthopedics, Catholic University of Sacred Heart, Rome, Italy
    Eur J Public Health 23:858-62. 2013
    ..This is defined by seven health metrics identified by the American Heart Association. Aim of the present study was to assess prevalence and distribution of these seven CV health metrics within an unselected population...
  57. ncbi request reprint Pharmacoepidemiology and disability in older adults: can medications slow the age-related decline in physical function?
    Anna Savo
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Roma, Italy
    Expert Opin Pharmacother 5:407-13. 2004
    ..The findings of these studies are not definite and need to be confirmed in large clinical trials...
  58. doi request reprint Predictors of rehabilitation outcome among frail elderly patients living in the community
    Domenico Fusco
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, Rome, Italy
    J Am Med Dir Assoc 10:335-41. 2009
    ..The purpose of this study is to evaluate the association of medical indicators of health status on functional recovery during rehabilitation of frail elderly living in the community...
  59. ncbi request reprint Sexual satisfaction and risk of disability in older women
    Graziano Onder
    Sticht Center on Aging, Section on Gerontology and Geriatrics, Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, N C, USA
    J Clin Psychiatry 64:1177-82. 2003
    ....
  60. ncbi request reprint Conventional or atypical antipsychotics and the risk of femur fracture among elderly patients: results of a case-control study
    Rosa Liperoti
    Center for Medicine of Aging, Department of Gerontology and Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Clin Psychiatry 68:929-34. 2007
    ..The aim of this study was to estimate the effect of atypical and conventional antipsychotics on the risk of hospitalization for femur fracture...
  61. doi request reprint Vitamin D receptor polymorphisms and falls among older adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Bone Miner Res 23:1031-6. 2008
    ..Further studies conducted in larger population are needed to confirm the association of BsmI genotype and falls and to understand reasons for these findings...
  62. doi request reprint Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older: the GerontoNet ADR risk score
    Graziano Onder
    Department of Geriatrics, Policlinico A Gemelli, Catholic University of the Sacred Heart, Rome, Italy
    Arch Intern Med 170:1142-8. 2010
    ..The aim of the present study was to develop and validate a method of identifying elderly patients who are at increased risk for an adverse drug reaction (ADR)...
  63. ncbi request reprint Physical activity and mortality in frail, community-living elderly patients
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 59:833-7. 2004
    ..The authors describe the prevalence of moderate-intensity physical activity in a population of older persons living in the community. In addition, they explore the relationship between physical activity and mortality...
  64. doi request reprint Mini Mental State Examination over time in chronic hemodialysis patients
    Maurizio Bossola
    Hemodialysis Service, Department of Surgery, Catholic University of the Sacred Heart, Rome, Italy
    J Psychosom Res 71:50-4. 2011
    ..The present study aimed to evaluate if changes in Mini Mental State Examination (MMSE) over time in hemodialysis (HDP) and elderly (EP) patients differ significantly and determine the variables associated with such possible changes...
  65. ncbi request reprint Prevalence and risk factors for falls in an older community-dwelling population
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatric Sciences, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 57:M722-6. 2002
    ..The aim of this study was to determine the prevalence of falls and related intrinsic and extrinsic risk factors in a community-dwelling older population...
  66. ncbi request reprint Change in physical performance over time in older women: the Women's Health and Aging Study
    Graziano Onder
    Sticht Center on Aging, Section on Gerontology and Geriatrics, Department of Internal Medicine, Wake Forest University, School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 57:M289-93. 2002
    ....
  67. doi request reprint Development of CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project: rationale and methodology
    Domenico Fusco
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Drugs Aging 26:3-13. 2009
    ..Once completed these recommendations should be validated in interventional studies...
  68. doi request reprint Prevalence and risk factors of sarcopenia among nursing home older residents
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    J Gerontol A Biol Sci Med Sci 67:48-55. 2012
    ..We evaluated the prevalence of sarcopenia and its association with functional and clinical status in a population of elderly persons aged 70 years and older living in nursing homes...
  69. ncbi request reprint Adverse drug reactions and cognitive function among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Clin Pharmacol 58:371-7. 2002
    ..To explore the relationship between cognitive function and the detection of adverse drug reactions (ADRs) and to evaluate whether cognitive function could influence the association between age and ADRs...
  70. ncbi request reprint Effects of an occupational therapy program on functional outcomes in older stroke patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:85-91. 2006
    ..Objective: To evaluate the efficacy of occupational therapy programs in patients with a recent stroke...
  71. ncbi request reprint NSAID-related psychiatric adverse events: who is at risk?
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Drugs 64:2619-27. 2004
    ..Prescribers should consider warning patients of the possibility of an acute neuropsychiatric event when traditional NSAIDs or selective COX-2 inhibitors are prescribed...
  72. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
    ..Management options for pressure ulcers include local wound care; surgical repair; and, more recently, topical application of growth factors...
  73. ncbi request reprint Physical performance and longevity in aged rats
    Christy S Carter
    Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 57:B193-7. 2002
    ....
  74. ncbi request reprint A case of normal-pressure hydrocephalus associated with rheumatoid arthritis
    Chiara Catananti
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, Largo F Vito 1, Rome, Italy
    Aging Clin Exp Res 22:189-91. 2010
    ..We analyse previous case reports describing a relationship between RA and normal-pressure hydrocephalus, and discuss potential mechanisms underlying this association...
  75. doi request reprint Executive function and metacognitive self-awareness after severe traumatic brain injury
    Umberto Bivona
    Post Coma Unit, Fondazione Santa Lucia, Rome, Italy
    J Int Neuropsychol Soc 14:862-8. 2008
    ..The significant correlation found between some components of executive system and metacognitive self-awareness confirmed the importance of addressing this issue to treat SA contextually in the rehabilitation of executive functions...
  76. ncbi request reprint Predictors of rehabilitation outcomes in frail patients treated in a geriatric hospital
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 50:679-84. 2002
    ..To evaluate the effect of medical indicators of health status on functional gain during rehabilitation of frail older patients...
  77. pmc Characteristics of nondisabled older patients developing new disability associated with medical illnesses and hospitalization
    Stefano Volpato
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology, and Geriatrics, University of Ferrara, Ferrara, Italy
    J Gen Intern Med 22:668-74. 2007
    ..To identify demographic, clinical, and biological characteristics of older nondisabled patients who develop new disability in basic activities of daily living (BADL) during medical illnesses requiring hospitalization...
  78. pmc Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    Am J Clin Nutr 83:1142-8. 2006
    ..Frailty is a common condition in elders and identifies a state of vulnerability for adverse health outcomes...
  79. ncbi request reprint Anemia and recovery from disability in activities of daily living in hospitalized older persons
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    J Am Geriatr Soc 54:632-6. 2006
    ..To evaluate the predictive value of hemoglobin levels upon hospital admission on recovery from activity of daily living (ADL) disability during hospital stay in older patients...
  80. ncbi request reprint Anemia, physical disability, and survival in older patients with heart failure
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Card Fail 12:533-9. 2006
    ..The effect of anemia on functional ability in heart failure has not been described. We evaluated the relationship of anemia, physical disability, and survival in patients with heart failure...
  81. ncbi request reprint In a prospective observational study, influenza vaccination prevented hospitalization among older home care patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, 00168 Rome, Italy
    J Clin Epidemiol 59:1072-7. 2006
    ..The aim of the study is (1) to describe the prevalence of vaccination against influenza in older home care patients and (2) to investigate the protective effect of influenza vaccination for hospitalization events...
  82. ncbi request reprint Non malignant daily pain and risk of disability among older adults in home care in Europe
    Manuel Soldato
    Department of Gerontology, Catholic University of Sacred Heart, Roma, Italy
    Pain 129:304-10. 2007
    ..36; 95% CI: 1.05-1.78). The risk of disability increased with pain severity and with number of painful sites. In conclusion among old subjects living in the community, daily pain is associated with an increased risk of disability...
  83. ncbi request reprint HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study)
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Age Ageing 36:514-20. 2007
    ..We evaluate the relationship of HDL-cholesterol with measures of physical performance, muscle strength, and functional status in older persons aged 80years or older...
  84. ncbi request reprint Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Int J Hematol 85:294-9. 2007
    ..This finding suggests that the growth hormone/IGF axis may play an important role in hematopoiesis, and it may be implicated in the age-related decline in hemoglobin concentration...
  85. ncbi request reprint Effects of influenza vaccination on mortality among frail, community-living elderly patients: an observational study
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric Medicine, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:254-8. 2003
    ..The aims of the present study were to describe the prevalence of vaccination against influenza in a population of older people living in the community, and to examine the relationship between influenza vaccination and mortality...
  86. ncbi request reprint Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study)
    Andrea Russo
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Geriatr Psychiatry Neurol 20:131-7. 2007
    ..In conclusion, physical performance and functional status measures are significantly and negatively influenced by the presence of depression in community-dwelling older persons aged 80 years and older...
  87. ncbi request reprint Anemia status, hemoglobin concentration, and mortality in nursing home older residents
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    J Am Med Dir Assoc 8:322-7. 2007
    ..Anemia status is a typical feature of the "frailty syndrome" of elderly subjects. Increasing evidences suggest that low hemoglobin concentration is common in elderly subjects and adversely affects morbidity and mortality...
  88. ncbi request reprint Community care in Europe. The Aged in Home Care project (AdHOC)
    Iain Carpenter
    Centre for Health Services Studies, University of Kent, United Kingdom
    Aging Clin Exp Res 16:259-69. 2004
    ..This paper describes the study and baseline data...
  89. ncbi request reprint Diffuse idiopathic skeletal hyperostosis: an uncommon case of dysphagia in an older adult
    Alessia Federici
    Department of Geriatrics, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:343-6. 2003
    ..In conclusion, DISH should be considered an important, although rare, cause of dysphagia among older adults. However, it should not be accepted as the cause of dysphagia until all other causes have been ruled out...
  90. ncbi request reprint Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure
    Giuseppe Zuccala
    Catholic University, Department of Gerontology, Geriatrics, and Physiatrics, L go F Vito, I 00168 Rome, Italy
    Eur Heart J 26:226-33. 2005
    ..Our aim was to assess whether starting treatment with ACE-inhibitors might improve cognition in patients with heart failure...
  91. ncbi request reprint Preoperative assessment and risk factors in the surgical treatment of lung cancer: the role of age
    Graziano Onder
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Centro Medicina dell Invecchiamento Università Cattolica Sacro Cuore, Policlinico A Gemelli, Roma, Italy
    Rays 29:407-11. 2004
    ....
  92. ncbi request reprint Depression and adverse drug reactions
    Graziano Onder
    Arch Intern Med 163:2395. 2003
  93. ncbi request reprint Angiotensin-converting enzyme inhibition intervention in elderly persons: effects on body composition and physical performance
    Christy S Carter
    University of Florida, Department of Aging and Geriatric Research, 1329 SW 16th St PO Box 100143, Gainesville FL, 32610 0143, USA
    J Gerontol A Biol Sci Med Sci 60:1437-46. 2005
    ..Promising pharmacoepidemiological studies and experimental evidence in animals suggest that there are appropriate models in which to study this effect...
  94. ncbi request reprint Association of calcium channel blocker use and pregnancy-associated plasma protein-A among older adults with hypertension: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Italy
    J Gerontol A Biol Sci Med Sci 62:1274-8. 2007
    ..The aim of the present cross-sectional study was to evaluated if, among older hypertensive adults, PAPP-A levels differ according to use of CCB...
  95. ncbi request reprint Fellowships for geriatric study in Italy
    Graziano Onder
    Aging Clin Exp Res 18:462. 2006
  96. ncbi request reprint Cross-sectional association between behavioral symptoms and potential elder abuse among subjects in home care in Italy: results from the Silvernet Study
    Luciana Ogioni
    Geriatrics Sector, Federal University of Rio de Janeiro UFRJ, Home for Ageing of Aeronáutica, Rio de Janeiro, Brazil
    Am J Geriatr Psychiatry 15:70-8. 2007
    ..The objectives of this study were to evaluate the prevalence of potential elder abuse among older adults receiving home care and to assess the association between behavioral symptoms and potential abuse...
  97. ncbi request reprint Effects of ACE inhibitors on skeletal muscle
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168, Rome Italy
    Curr Pharm Des 12:2057-64. 2006
    ....
  98. ncbi request reprint Physical function, physical activity and recent falls. Results from the "Invecchiamento e Longevità nel Sirente (ilSIRENTE)" Study
    Irene Mangani
    Department of Critical Care Medicine and Surgery, Unit of Geriatric Medicine, University of Florence, Florence, Italy
    Aging Clin Exp Res 20:234-41. 2008
    ....