Isabel G Newton
Affiliation: Wake Forest University School of Medicine
- Caloric restriction does not reverse aging-related changes in hippocampal BDNFIsabel G Newton
Department of Neurobiology, Medical Center Boulevard, Winston Salem, NC 27157 1010, USA
Neurobiol Aging 26:683-8. 2005..Furthermore, if CRs attenuation of aging-related memory changes is mediated by BDNF, then it must be through a small, CA1-specific increase and does not involve reversal of an aging-related decline in BDNF...
- Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasisLei Shi
Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157 1010, USA
Exp Neurol 206:70-9. 2007..CR eliminates that aging-related decline by inducing stable NMDA and AMPA receptor subunit levels...
- Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning abilityMichelle M Adams
Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Exp Neurol 211:141-9. 2008..This age-related decrease and CR-induced stabilization are likely to affect CA3 synaptic plasticity and, as a result, hippocampal function...
- Effects of aging and caloric restriction on dentate gyrus synapses and glutamate receptor subunitsIsabel G Newton
Department of Neurobiology and Anatomy, Medical Center Boulevard, Wake Forest University School of Medicine, Winston Salem, NC 27157 1010, USA
Neurobiol Aging 29:1308-18. 2008..Instead, it is due to subunit decreases in young CR rats to levels that are sustained in CR rats throughout lifespan, but that are reached in AL rats only in old age...