Research Topics
Species | Mariana MureaSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
|
Detail Information
Publications
Lipotoxicity in diabetic nephropathy: the potential role of fatty acid oxidationMariana Murea
Department of Internal Medicine Nephrology Section, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157 1053, USA
Clin J Am Soc Nephrol 5:2373-9. 2010..This novel glucolipotoxicity hypothesis in T2DN warrants further investigation...
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetesMariana Murea
Department of Internal Medicine, Section on Nephrology, Wake Forest University Baptist Medical Center, Winston Salem, NC 27157 1053, USA
Am J Nephrol 33:502-9. 2011..African-Americans (AAs) with diabetes have high incidence rates of end-stage renal disease (ESRD) with associated high mortality. Genetic factors modulating the risk of mortality on dialysis are poorly understood...
Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal diseaseBarry I Freedman
Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1053, USA
Kidney Int 82:805-11. 2012..After adjustment, two APOL1 risk variants weakly predict mild forms of kidney disease. Second hits appear necessary for the initiation of APOL1-associated nephropathy...
Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African AmericansBarry I Freedman
Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC, USA
Nephrol Dial Transplant 26:3805-10. 2011..Plasma HDL particle subclass concentrations were compared in 73 African Americans based on APOL1 genotypes to detect differences potentially contributing to renal disease...
The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African AmericansBarry I Freedman
Section on Nephrology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1053, USA
Am J Nephrol 32:66-72. 2010..Since MYH9 underlies approximately 40% of end-stage renal disease (ESRD) in AA, we tested for genetic association with LN...
Target organ damage in African American hypertension: role of APOL1Barry I Freedman
Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC 27157 1053, USA
Curr Hypertens Rep 14:21-8. 2012..Discovery of APOL1-associated nephropathy was a major success of the genetics revolution, demonstrating that secondary hypertension is typically present in nondiabetic African Americans with nephropathy...
The effect of ACACB cis-variants on gene expression and metabolic traitsLijun Ma
Wake Forest School of Medicine, Winston Salem, North Carolina, United States of America
PLoS ONE 6:e23860. 2011..We sought to determine whether ACACB transcribed variants were associated with ACACB gene expression and insulin sensitivity in non-diabetic African American (AA) and European American (EA) adults...
Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart StudyMariana Murea
Department of Internal Medicine Nephrology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC, 27157 1053, USA
BMC Nephrol 13:148. 2012..Relationships between serum MCP-1 concentration and early nephropathy and subclinical cardiovascular disease (CVD) were assessed in African Americans (AAs) with type 2 diabetes (T2D)...
Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complicationsMariana Murea
Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
Rev Diabet Stud 9:6-22. 2012..It is expected that novel strategies to exploit the gene- and exposure-related underpinnings of T2D will soon result...
Glycated albumin, not hemoglobin A1c, predicts cardiovascular hospitalization and length of stay in diabetic patients on dialysisMariana Murea
Department of Internal Medicine Nephrology, Wake Forest School of Medicine, Winston Salem, NC, USA
Am J Nephrol 36:488-96. 2012..Relationships between GA, HbA1c, and casual plasma glucose (PG) with cause-specific cardiovascular (CV) disease, infectious disease (ID), and vascular access- (VA) related hospitalization rates and length of stay (LOS) were assessed...
Potential effects of MYH9-associated nephropathy on dialysis and kidney transplant outcomesBarry I Freedman
Section on Nephrology, Department of Internal Medicine, Wake Forest University, School of Medicine, Winston Salem, North Carolina 27157 1053, USA
Semin Dial 23:244-7. 2010..MYH9 polymorphisms may affect treatment outcomes in severe kidney disease and such gene effects are rarely encountered in practice...
Essential hypertension and risk of nephropathy: a reappraisalMariana Murea
Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
Curr Opin Nephrol Hypertens 19:235-41. 2010..The pathogenesis of these disparate renal syndromes is reviewed...
