Research Topics
Species | Preston R MillerSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Publications
Prospective evaluation of vacuum-assisted fascial closure after open abdomen: planned ventral hernia rate is substantially reducedPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Ann Surg 239:608-14; discussion 614-6. 2004..The goal of this report is to examine the success of vacuum-assisted fascial closure (VAFC) under a carefully applied protocol in abdominal closure after open abdomen...
Optimal threshold for diagnosis of ventilator-associated pneumonia using bronchoalveolar lavagePreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 55:263-7; discussion 267-8. 2003..In this project, the effects of lower diagnostic cutoffs on VAP diagnosis and unnecessary antibiotic use are examined...
A practical application of practice-based learning: development of an algorithm for empiric antibiotic coverage in ventilator-associated pneumoniaPreston R Miller
Department of Surgery, Wake Forest University Bowman Gray School of Medicine, Winston Salem, NC 27157, USA
J Trauma 60:725-9; discussion 729-31. 2006..Our goal was to describe the successful application of PBL to patient care improvement with development of an algorithm for the empiric therapy of ventilator-associated pneumonia (VAP)...
Complex blunt aortic injury or repair: beneficial effects of cardiopulmonary bypass usePreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27514, USA
Ann Surg 237:877-83; discussion 883-4. 2003..Special consideration is given to the influence of bypass in the outcome of complex injuries or repair circumstances...
External fixation or arteriogram in bleeding pelvic fracture: initial therapy guided by markers of arterial hemorrhagePreston R Miller
Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
J Trauma 54:437-43. 2003..Our aim was to evaluate markers of arterial bleeding in patients with BPF, thus identifying patients requiring early ANGIO regardless of fracture pattern...
Late fascial closure in lieu of ventral hernia: the next step in open abdomen managementPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27514, USA
J Trauma 53:843-9. 2002..We review a method of late primary fascial closure, thus eliminating the need for delayed reconstruction in some patients...
National nosocomial infection surveillance system: from benchmark to bedside in trauma patientsPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Trauma 60:98-103. 2006..This relies on a combination of clinical and culture data. Our goal was to evaluate the accuracy of the NNIS definition as compared with BAL diagnosis in trauma patients...
Current issues in traumaTimothy C Fabian
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Curr Probl Surg 39:1160-244. 2002
Emergency department length of stay is an independent predictor of hospital mortality in trauma activation patientsNathan T Mowery
Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Trauma 70:1317-25. 2011..Our hypothesis is that increased ED length of stay (LOS) leads to increased hospital mortality in patients not undergoing immediate surgical intervention...
Colonic resection in the setting of damage control laparotomy: is delayed anastomosis safe?Preston R Miller
Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
Am Surg 73:606-9; discussion 609-10. 2007..To our knowledge, this represents the first reported series of DA after DCL, an area in which further work is needed to carefully define indications for the safe application of this concept...
Increased insulin requirements are associated with pneumonia after severe injuryR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 63:358-64. 2007..Little is known about how insulin requirements are affected by the presence of infection, and therefore, the purpose of this study was to characterize this relationship...
Relationship of early hyperglycemia to mortality in trauma patientsAmanda M Laird
Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
J Trauma 56:1058-62. 2004..However, aggressive maintenance of levels <110 mg/dL as reported by others may not be necessary...
Traumatic pulmonary pathology measured with computed tomography and a semiautomated analytic methodMelissa Daly
Virginia Tech Wake Forest University School of Biomedical Engineering and Sciences, Center for Injury Biomechanics, Medical Center Boulevard, Winston Salem, NC 27157, USA
Clin Imaging 32:346-54. 2008..When used to predict which patients were at risk for ARDS, the method presented in this study had a sensitivity of 57% and a specificity of 100%...
Multiplicity of solid organ injury: influence on management and outcomes after blunt abdominal traumaAjai K Malhotra
Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, 23298, USA
J Trauma 54:925-9. 2003..The current study was undertaken to examine how concomitant injury to liver and spleen after blunt abdominal trauma affects management and outcomes...
Blunt aortic injury with concomitant intra-abdominal solid organ injury: treatment priorities revisitedJohn M Santaniello
Department of Surgery, Loyola University Medical Center, Stritch School of Medicine, Maywook, Illinois 60153, USA
J Trauma 53:442-5; discussion 445. 2002..We evaluated the safety of nonoperative management (NOM) of blunt L/S injuries in patients undergoing acute BAI repair with bypass...
Prospective comparison of bronchoalveolar lavage and quantitative deep tracheal aspirate in the diagnosis of ventilator associated pneumoniaMatthew M Mondi
Department of Surgery, Wake Forest University Bowman Gray School of Medicine, Winston-Salem, NC 27157, USA
J Trauma 59:891-5; discussion 895-6. 2005..With the increasing problems associated with excess antibiotic use, we believe these results support the use of BAL over QDEA in the diagnosis of VAP in the ventilated trauma patient...
National Trauma Institute prospective evaluation of the ventilator bundle in trauma patients: does it really work?Martin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma Acute Care Surg 74:354-60; discussion 360-2. 2013..To provide evidence of its efficacy, the National Trauma Institute organized a prospective multi-institutional trial to evaluate the utility of the VB...
Does Acute Physiology and Chronic Health Evaluation II Provide a Valid Metric to Directly Compare Disease Severity in Trauma versus Surgical Intensive Care Unit Patients?Robert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
Am Surg 78:1261-9. 2012..Improved severity scoring systems are needed to conduct clinically relevant and methodologically valid comparisons between these unique groups...
Non-helmeted motorcyclists: a burden to society? A study using the National Trauma Data BankJonathan C Hundley
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 57:944-9. 2004..In this study, we evaluated the effect that helmet use had upon injury severity, outcome controlling for alcohol or drug use, resource utilization, and financial burden using the National Trauma Data Bank (NTDB)...
Validation of stroke work and ventricular arterial coupling as markers of cardiovascular performance during resuscitationR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 60:930-4; discussion 934-5. 2006..The purpose of this study was to demonstrate the capabilities of a completely automated data management system by further evaluating SWI-based resuscitation...
Injury-associated hypothermia: an analysis of the 2004 National Trauma Data BankR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Shock 24:114-8. 2005..Although shock severity is highly indicative of outcome, hypothermia independently contributes to the substantial mortality associated with severe injury...
An innovative approach to predict the development of adult respiratory distress syndrome in patients with blunt traumaRobert D Becher
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
J Trauma Acute Care Surg 73:1229-35. 2012..In this study, we test the hypothesis that a novel method that objectively measures percent PC can be used to identify patients at risk to develop ARDS after injury...
Does gender difference influence outcome?Martin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis 38163, USA
J Trauma 53:889-94. 2002..We evaluated the effect of gender on various outcomes in trauma patients...
Are plain radiographs of the spine necessary during evaluation after blunt trauma? Accuracy of screening torso computed tomography in thoracic/lumbar spine fracture diagnosisGabriel E Berry
Department of Surgery and Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 59:1410-3; discussion 1413. 2005..The objective of this study is to determine whether the data obtained from admission chest/abdomen/pelvis (CAP) computed tomography (CT) scans after blunt trauma has utility in thoracolumbar spine evaluation...
Novel resuscitation strategy for pulmonary contusion after severe chest traumaMichael E Kelly
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 55:94-105. 2003....
The trend of using computed tomography in the detection of acute thoracic aortic and branch vessel injury after blunt thoracic trauma: single-center experience over 13 yearsMichael Y M Chen
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1088, USA
J Trauma 56:783-5. 2004..The purpose of this study was to review the trend of using chest computed tomography (CT) and aortography in evaluating patients with blunt thoracic trauma...
Systemic inflammation worsens outcomes in emergency surgical patientsRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma Acute Care Surg 72:1140-9. 2012..This study sought to determine the influence of preoperative systemic inflammation on postoperative outcome in patients requiring emergent colon surgery...
A semi-automated approach for measuring splenic injury using computed tomographyKerry A Danelson
Wake Forest University School of Medicine School of Biomedical Engineering and Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Biomed Sci Instrum 43:13-7. 2007..The results demonstrated as the AIS grade increased, the percent injury volume increased. In conclusion, it is possible to calculate injury volumes from abdominal CT scans with minimal user inputs...
A critical assessment of outcomes in emergency versus nonemergency general surgery using the American College of Surgeons National Surgical Quality Improvement Program databaseRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Am Surg 77:951-9. 2011..This data suggests that there is a need for improvement in both methods and systems of care for the emergent population...
Acute respiratory distress syndrome in blunt trauma: identification of independent risk factorsPreston R Miller
Department of Surgery, The University of Tennessee Health Science Center, Memphis 38163, USA
Am Surg 68:845-50; discussion 850-1. 2002..Improvement in understanding of which patients are actually at risk may allow for advances in treatment as well as prevention in the future...
Risk of thoracolumbar fractures doubled in victims of motor vehicle collisions with cervical spine fracturesJames E Winslow
Wake Forest University Health Sciences, Winston Salem, North Carolina 27157 1089, USA
J Trauma 61:686-7. 2006..We sought to determine the actual association between these injuries in a large nationwide data set...
Acute care surgery: impact on practice and economics of elective surgeonsPreston R Miller
Department of Surgery, Wake Forest University, Winston Salem, NC 27157, USA
J Am Coll Surg 214:531-5; discussion 536-8. 2012..The aim of this project is to examine the impact in terms of work relative value units (wRVUs), collections, and cases in both groups with creation of an acute care surgery service at our institution...
Creation and implementation of an emergency general surgery registry modeled after the National Trauma Data BankRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Am Coll Surg 214:156-63. 2012..The hypothesis was that creating standardized ICD-9-based inclusion criteria would facilitate patient identification for an EGSR and aid in its ongoing development...
The pathogenesis of pulmonary contusion: an open chest model in the ratJ Jason Hoth
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 61:32-44; discussion 44-5. 2006..Herein we describe an open chest model of pulmonary contusion (PC) in a rodent (rat) and have identified a possible role for CC and CXC chemokines in the pathogenesis of PC...
Multidrug-resistant pathogens and pneumonia: comparing the trauma and surgical intensive care unitsRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Surg Infect (Larchmt) 12:267-72. 2011..Our hypothesis was that SICU patients would have a higher incidence of multi-drug-resistant (MDR) organisms causing VAP/HAP, possibly contributing to inadequate empiric antibiotic (IEA) coverage...
Locally derived versus guideline-based approach to treatment of hospital-acquired pneumonia in the trauma intensive care unitRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Surg Infect (Larchmt) 13:352-9. 2012..Our hypothesis was that an empiric algorithm supported by our locally-driven analysis would predict more accurate coverage than one defined strictly by an unmodified guideline-driven approach...
Elevated admission white blood cell count in pregnant trauma patients: an indicator of ongoing placental abruptionShuchi Shah
Department of General Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
Am Surg 68:644-7. 2002..Conversely WBC <20,000/mm3 rules out PA in the pregnant trauma patient (negative predictive value of 100%)...
Associated injuries in blunt solid organ trauma: implications for missed injury in nonoperative managementPreston R Miller
Department of Surgery, University of Tennessee Health Science Center, Memphis 38163, USA
J Trauma 53:238-42; discussion 242-4. 2002..We speculate that the greater amount and/or different vector of energy transfer needed to injure the liver versus the spleen accounts for the greater rate of associated injuries to the pancreas/small bowel...
Aberrant obturator artery is a common arterial variant that may be a source of unidentified hemorrhage in pelvic fracture patientsJay A Requarth
Section of Vascular and Interventional Radiology, Department of Radiologic Sciences, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Trauma 70:366-72. 2011..The purpose of this study was to describe the incidence of the AOA using angiography and determine the sensitivity of 64-slice computed tomography angiography (CTA) at identifying the AOA...
Surgical intensive care unit mobility is increased after institution of a computerized mobility order set and intensive care unit mobility protocol: a prospective cohort analysisAmy N Hildreth
Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
Am Surg 76:818-22. 2010..Further studies should focus on measurement of the effect of mobility interventions on patient outcomes...
The splenic artery stump pressure is affected by arterial anatomy after proximal embolotherapy in blunt splenic injuryJay Anthony Requarth
Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, North Carolina 27106, USA
J Trauma Acute Care Surg 73:1221-4. 2012..Proximal splenic artery embolotherapy can be used as an adjunct to nonoperative management of blunt splenic injury (BSI); however, the hemodynamic changes in the distal splenic artery after proximal splenic artery occlusion are unknown...
Nonoperative management of adult blunt splenic injury with and without splenic artery embolotherapy: a meta-analysisJay A Requarth
Section of Vascular and Interventional Radiology, Department of Radiologic Sciences, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Trauma 71:898-903; discussion 903. 2011..This meta-analysis compares the known outcomes data for observational management versus SAE by splenic injury grade cohort...
Prospective screening for blunt cerebrovascular injuries: analysis of diagnostic modalities and outcomesPreston R Miller
Department of Surgery, The University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Ann Surg 236:386-93; discussion 393-5. 2002..However, less-invasive diagnostic techniques (CTA and MRA) are inadequate for screening. Technological advances are necessary before abandonment of conventional angiography, which remains the standard for diagnosis...
Vacuum-assisted closure for defects of the abdominal wallAnthony J DeFranzo
Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157 1075, USA
Plast Reconstr Surg 121:832-9. 2008..Ideally, reconstruction should be performed on a nonedematous, clean tissue bed with bacterial levels less than 10 bacteria/cm in a well-nourished patient...
Improving outcomes following penetrating colon wounds: application of a clinical pathwayPreston R Miller
Department of Surgery, The University of Tennessee Health Science Center, Memphis, 38163, USA
Ann Surg 235:775-81. 2002..The data demonstrated the need for colostomy in the face of shock and comorbidities. Institution of this pathway results in colostomy for only 7% of all colon wounds...
Resuscitation with a novel hemoglobin-based oxygen carrier in a Swine model of uncontrolled perioperative hemorrhageAjai K Malhotra
Department of Surgery, University of Tennessee Health Science Center, Memphis, USA
J Trauma 54:915-24. 2003..The current study evaluates the efficacy of this novel compound for resuscitation in a swine model of uncontrolled perioperative hemorrhage...
