Research Topics
| STEPHEN MESSIERSummaryAffiliation: Wake Forest University Country: USA Publications
Research Grants
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Detail Information
Publications
Declines in strength and balance in older adults with chronic knee pain: a 30-month longitudinal, observational studyStephen P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, North Carolina 27109, USA
Arthritis Rheum 47:141-8. 2002....
Diet and exercise for obese adults with knee osteoarthritisStephen P Messier
Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Clin Geriatr Med 26:461-77. 2010....
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationaleStephen P Messier
Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC, USA
BMC Musculoskelet Disord 10:93. 2009..This article describes the intervention, the empirical evidence to support it, and test-retest reliability data...
Obesity and osteoarthritis: disease genesis and nonpharmacologic weight managementStephen P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Med Clin North Am 93:145-59, xi-xii. 2009....
Risk factors and mechanisms of knee injury in runnersStephen P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Med Sci Sports Exerc 40:1873-9. 2008..5 million running at least 100 d x yr(-1). Although running injuries are well understood medically, their potential risk factors are not. Thus, we presently have limited ability to identify individuals at high risk for overuse injuries...
Obesity and osteoarthritis: disease genesis and nonpharmacologic weight managementStephen P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Rheum Dis Clin North Am 34:713-29. 2008....
Physical activity and weight loss interventions in older adults with knee osteoarthritisStephen P Messier
J. B. Snow Biomechanics Laboratory, Department of Health and Sport Science, Wake Forest University, Winston-Salem, NC 27109, USA
N C Med J 68:436-8. 2007
Glucosamine/chondroitin combined with exercise for the treatment of knee osteoarthritis: a preliminary studyS P Messier
Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, United States
Osteoarthritis Cartilage 15:1256-66. 2007....
Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking?S P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Osteoarthritis Cartilage 19:272-80. 2011..The aim of this study was to examine the effects of high weight loss on knee joint loads during walking in participants with knee osteoarthritis (OA)...
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion TrialStephen P Messier
Claude D Pepper Older Americans Independence Center, Wake Forest University, Winston Salem, NC 27109, USA
Arthritis Rheum 50:1501-10. 2004....
Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritisStephen P Messier
Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, North Carolina 27109, USA
Arthritis Rheum 52:2026-32. 2005..To determine the relationship between change in body mass and knee-joint moments and forces during walking in overweight and obese older adults with knee osteoarthritis (OA) following an 18-month clinical trial of diet and exercise...
Inflammatory markers and physical function among older adults with knee osteoarthritisBrenda W J H Penninx
Sticht Center on Aging, Department of Internal Medicine, Wake Forest University School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157, USA
J Rheumatol 31:2027-31. 2004..CONCLUSION: Especially high levels of the soluble receptors of TNF-alpha were found to be associated with lower physical function, increased OA symptoms, and worse knee radiographic scores in older obese adults with knee OA...
Knee strength maintained despite loss of lean body mass during weight loss in older obese adults with knee osteoarthritisXuewen Wang
Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 62:866-71. 2007..The effects of weight loss on muscle function in older adults have not been well studied. This study determined the effects of a 6-month weight-loss intervention on muscle strength and quality in older obese adults with knee osteoarthritis...
Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trialBarbara J Nicklas
Wake Forest University School of Medicine, Winston Salem, NC, USA
Am J Clin Nutr 79:544-51. 2004..Persistent, low-grade inflammation is an independent predictor of several chronic diseases and all-cause mortality...
The effect of randomization to weight loss on total mortality in older overweight and obese adults: the ADAPT StudyM Kyla Shea
Sticht Center on Aging, Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 65:519-25. 2010..Data from the Arthritis, Diet, and Activity Promotion Trial (ADAPT) were used to determine whether randomization to a weight reduction program was associated with total mortality in overweight/obese older adults...
The Arthritis, Diet and Activity Promotion Trial (ADAPT): design, rationale, and baseline resultsGary D Miller
Department of Health and Exercise Science Wake Forest University, Winston Salem, North Carolina 27109, USA
Control Clin Trials 24:462-80. 2003..The results from ADAPT will provide approaches clinicians should recommend for behavioral therapies that effectively reduce the incidence of disability associated with knee OA...
Intensive weight loss program improves physical function in older obese adults with knee osteoarthritisGary D Miller
Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA
Obesity (Silver Spring) 14:1219-30. 2006..Physical function and body composition in older obese adults with knee osteoarthritis (OA) were examined after intensive weight loss...
Baseline balance and functional decline in older adults with knee pain: the Observational Arthritis Study in SeniorsAnthony P Marsh
Department of Health and Exercise Science, Gymnasium Building Room 313, Wake Forest University, Winston Salem, NC 27109, USA
J Am Geriatr Soc 51:331-9. 2003..To examine the cross-sectional and longitudinal effect of baseline balance, independent of multiple covariates (sociodemographic variables, comorbidities), on self-reported disability and several measures of functional performance...
Do older adults with knee osteoarthritis place greater loads on the knee during gait? A preliminary studyStephen P Messier
J B Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winton Salem, NC 27109, USA
Arch Phys Med Rehabil 86:703-9. 2005....
Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritisBarbara J Nicklas
Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 60:1292-8. 2005....
Long-term exercise therapy resolves ethnic differences in baseline health status in older adults with knee osteoarthritisCapri Gabrielle Foy
Department of Public Health Sciences, Wake Forest University, Winston Salem, North Carolina, USA
J Am Geriatr Soc 53:1469-75. 2005....
Effects of exercise adherence on physical function among overweight older adults with knee osteoarthritisCoen H van Gool
Universiteit Maastricht, Maastricht, The Netherlands
Arthritis Rheum 53:24-32. 2005..To determine whether high exercise adherence improved physical function among older adults with knee osteoarthritis (OA) who were overweight or obese...
Exercise, self-efficacy, and mobility performance in overweight and obese older adults with knee osteoarthritisBrian C Focht
Ohio State University, Columbus, 43210, USA
Arthritis Rheum 53:659-65. 2005....
Determinants of high and low attendance to diet and exercise interventions among overweight and obese older adults. Results from the arthritis, diet, and activity promotion trialCoen H van Gool
Department of Health Care Studies, Section of Medical Sociology, Universiteit Maastricht, Maastricht, The Netherlands
Contemp Clin Trials 27:227-37. 2006..Therefore, we explored demographic, health-related, and social determinants of high and low attendance to diet and exercise sessions among overweight and obese patients with knee osteoarthritis (> or = 60 years; N = 206)...
Research Grants
- Intensive Dietary Restriction with Exercise in ArthritisSTEPHEN MESSIER; Fiscal Year: 2007..This study could make intensive weight loss the standard-of- care for overweight and obese adults with knee OA, as it enhances our understanding of the OA disease process and weight-loss recommendations for older people generally. ..
- Intensive Dietary Restriction with Exercise in ArthritisSTEPHEN MESSIER; Fiscal Year: 2009..This study could make intensive weight loss the standard-of- care for overweight and obese adults with knee OA, as it enhances our understanding of the OA disease process and weight-loss recommendations for older people generally. ..
- Intensive Dietary Restriction with Exercise in ArthritisStephen P Messier; Fiscal Year: 2010..This study could make intensive weight loss the standard-of- care for overweight and obese adults with knee OA, as it enhances our understanding of the OA disease process and weight-loss recommendations for older people generally. ..
