Research Topics
| J Wayne MeredithSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Detail Information
Publications
Independently derived survival risk ratios yield better estimates of survival than traditional survival risk ratios when using the ICISSJ Wayne Meredith
Department of Surgery, Wake Forest Univeresity School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
J Trauma 55:933-8. 2003..Independent SRRs are derived from incidents where patients sustained only an isolated injury. The objective of this study is to compare the mortality prediction abilities of independent and traditional SRRs via the ICISS...- A comparison of the abilities of nine scoring algorithms in predicting mortalityJ Wayne Meredith
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 53:621-8; discussion 628-9. 2002..The purpose of this study was to compare the abilities of nine Abbreviated Injury Scale (AIS)- and (ICD-9)-based scoring algorithms in predicting mortality... - Thoracic trauma: when and how to interveneJ Wayne Meredith
Department of General Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Surg Clin North Am 87:95-118, vii. 2007..We review common injuries and scenarios that may be encountered by the surgeon and discuss the considerations and variables that enter into the decision-making process for operative intervention... - A fresh set of survival risk ratios derived from incidents in the National Trauma Data Bank from which the ICISS may be calculatedJ Wayne Meredith
Department of Surgery, Wake Forest Univeresity School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
J Trauma 55:924-32. 2003..The purpose of this study was to compare a new set of SRRs derived from the National Trauma Data Bank (NTDB) with SRRs derived years ago from the North Carolina Hospital Discharge Database (NCHDD)... - Increased insulin requirements are associated with pneumonia after severe injuryR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 63:358-64. 2007..Little is known about how insulin requirements are affected by the presence of infection, and therefore, the purpose of this study was to characterize this relationship... 
Centers for Medicare and Medicaid services quality indicators do not correlate with risk-adjusted mortality at trauma centersShahid Shafi
Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas, USA
J Trauma 68:771-7. 2010..We hypothesized that compliance with CMS quality indicators would correlate with risk-adjusted mortality rates in trauma patients...- Characterization of crash-induced thoracic loading resulting in pulmonary contusionF Scott Gayzik
Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
J Trauma 66:840-9. 2009..A technique to match CIREN cases to vehicle crash tests is applied to quantify the thoracic loading associated with this injury... - Traumatic pulmonary pathology measured with computed tomography and a semiautomated analytic methodMelissa Daly
Virginia Tech Wake Forest University School of Biomedical Engineering and Sciences, Center for Injury Biomechanics, Medical Center Boulevard, Winston Salem, NC 27157, USA
Clin Imaging 32:346-54. 2008..When used to predict which patients were at risk for ARDS, the method presented in this study had a sensitivity of 57% and a specificity of 100%... - Emergency department length of stay is an independent predictor of hospital mortality in trauma activation patientsNathan T Mowery
Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, North Carolina 27157, USA
J Trauma 70:1317-25. 2011..Our hypothesis is that increased ED length of stay (LOS) leads to increased hospital mortality in patients not undergoing immediate surgical intervention... - Validation of stroke work and ventricular arterial coupling as markers of cardiovascular performance during resuscitationR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 60:930-4; discussion 934-5. 2006..The purpose of this study was to demonstrate the capabilities of a completely automated data management system by further evaluating SWI-based resuscitation... 
Prospective evaluation of vacuum-assisted fascial closure after open abdomen: planned ventral hernia rate is substantially reducedPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Ann Surg 239:608-14; discussion 614-6. 2004..The goal of this report is to examine the success of vacuum-assisted fascial closure (VAFC) under a carefully applied protocol in abdominal closure after open abdomen...- Injury-associated hypothermia: an analysis of the 2004 National Trauma Data BankR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Shock 24:114-8. 2005..Although shock severity is highly indicative of outcome, hypothermia independently contributes to the substantial mortality associated with severe injury... - Prospective comparison of bronchoalveolar lavage and quantitative deep tracheal aspirate in the diagnosis of ventilator associated pneumoniaMatthew M Mondi
Department of Surgery, Wake Forest University Bowman Gray School of Medicine, Winston-Salem, NC 27157, USA
J Trauma 59:891-5; discussion 895-6. 2005..With the increasing problems associated with excess antibiotic use, we believe these results support the use of BAL over QDEA in the diagnosis of VAP in the ventilated trauma patient... - National nosocomial infection surveillance system: from benchmark to bedside in trauma patientsPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Trauma 60:98-103. 2006..This relies on a combination of clinical and culture data. Our goal was to evaluate the accuracy of the NNIS definition as compared with BAL diagnosis in trauma patients... - A practical application of practice-based learning: development of an algorithm for empiric antibiotic coverage in ventilator-associated pneumoniaPreston R Miller
Department of Surgery, Wake Forest University Bowman Gray School of Medicine, Winston Salem, NC 27157, USA
J Trauma 60:725-9; discussion 729-31. 2006..Our goal was to describe the successful application of PBL to patient care improvement with development of an algorithm for the empiric therapy of ventilator-associated pneumonia (VAP)... - Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusionJ Jason Hoth
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Shock 31:376-81. 2009..These results show that TLRs have a primary role in the response to acute lung injury. Lung inflammation and systemic innate immune responses are dependent on TLR activation by pulmonary contusion... - Relationship of early hyperglycemia to mortality in trauma patientsAmanda M Laird
Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
J Trauma 56:1058-62. 2004..However, aggressive maintenance of levels <110 mg/dL as reported by others may not be necessary... - Creation and implementation of an emergency general surgery registry modeled after the National Trauma Data BankRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
J Am Coll Surg 214:156-63. 2012..The hypothesis was that creating standardized ICD-9-based inclusion criteria would facilitate patient identification for an EGSR and aid in its ongoing development... - A population-based comparison of CIREN and NASS cases using similarity scoringJoel D Stitzel
Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
Annu Proc Assoc Adv Automot Med 51:395-417. 2007..Weighted NASS data and CIREN data were obtained for the years 2001-2005. NASS cases with Maximum AIS 3 resulted in a subset of 1,869 NASS cases, and 2,819 CIREN cases... - Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusionJ Jason Hoth
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Shock 28:447-52. 2007..These results show that TLR2 has a primary role in the neutrophil response to acute lung injury. We suggest that an unidentified noninfectious ligand generated by pulmonary contusion acts via TLR2 to generate inflammatory responses... - Non-helmeted motorcyclists: a burden to society? A study using the National Trauma Data BankJonathan C Hundley
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 57:944-9. 2004..In this study, we evaluated the effect that helmet use had upon injury severity, outcome controlling for alcohol or drug use, resource utilization, and financial burden using the National Trauma Data Bank (NTDB)... - Colonic resection in the setting of damage control laparotomy: is delayed anastomosis safe?Preston R Miller
Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
Am Surg 73:606-9; discussion 609-10. 2007..To our knowledge, this represents the first reported series of DA after DCL, an area in which further work is needed to carefully define indications for the safe application of this concept... - Systemic inflammation worsens outcomes in emergency surgical patientsRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma Acute Care Surg 72:1140-9. 2012..This study sought to determine the influence of preoperative systemic inflammation on postoperative outcome in patients requiring emergent colon surgery... - Acute care surgery: impact on practice and economics of elective surgeonsPreston R Miller
Department of Surgery, Wake Forest University, Winston Salem, NC 27157, USA
J Am Coll Surg 214:531-5; discussion 536-8. 2012..The aim of this project is to examine the impact in terms of work relative value units (wRVUs), collections, and cases in both groups with creation of an acute care surgery service at our institution... - A critical assessment of outcomes in emergency versus nonemergency general surgery using the American College of Surgeons National Surgical Quality Improvement Program databaseRobert D Becher
Acute Care Surgery Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Am Surg 77:951-9. 2011..This data suggests that there is a need for improvement in both methods and systems of care for the emergent population... - Age thresholds for increased mortality of three predominant crash induced head injuriesJoel D Stitzel
Wake Forest University School of Medicine, Winston Salem, NC, USA
Ann Adv Automot Med 52:235-44. 2008..This study has potential implications in the arena of safety design for the elderly, automated crash notification, and auto safety legislation... - Improving the Glasgow Coma Scale score: motor score alone is a better predictorC Healey
Department of Surgery, University of Vermont, College of Medicine, Burlington 05401, USA
J Trauma 54:671-8; discussion 678-80. 2003..Because the m component is nonlinear in the log odds of survival, however, it should be mathematically transformed before its inclusion in broader outcome prediction models... - The Trauma Quality Improvement Program: pilot study and initial demonstration of feasibilityMark R Hemmila
Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan 48109 5033, USA
J Trauma 68:253-62. 2010..This study details the feasibility and acceptance of TQIP among the participating centers... - Are plain radiographs of the spine necessary during evaluation after blunt trauma? Accuracy of screening torso computed tomography in thoracic/lumbar spine fracture diagnosisGabriel E Berry
Department of Surgery and Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 59:1410-3; discussion 1413. 2005..The objective of this study is to determine whether the data obtained from admission chest/abdomen/pelvis (CAP) computed tomography (CT) scans after blunt trauma has utility in thoracolumbar spine evaluation... - American Association for the Surgery of Trauma Organ Injury Scale I: spleen, liver, and kidney, validation based on the National Trauma Data BankGlen Tinkoff
Department of Surgery, Christiana Care Health System, Newark, DE, USA
J Am Coll Surg 207:646-55. 2008..This study attempts to validate the American Association for the Surgery of Trauma (AAST) Organ Injury Scale (OIS) for spleen, liver, and kidney injuries using the National Trauma Data Bank (NTDB)... - A finite element-based injury metric for pulmonary contusion: investigation of candidate metrics through correlation with computed tomographyF Scott Gayzik
Wake Forest University School of Medicine, Medical Center Blvd, MRI 2, Winston Salem, NC 27104, USA
Stapp Car Crash J 51:189-209. 2007..The study also presents a novel spatial validation technique for correlation of mathematical predictors to volumetric contusion data; a technique that may be extended to other injuries and modalities as well... - Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspectiveErnest E Moore
Department of Surgery, Denver Health, Denver, Colorado 80204, USA
J Trauma 70:334-9. 2011..The purpose of this prospective multicenter study was to identify injury patterns and physiologic profiles at ED arrival that are compatible with survival... - Videotape review leads to rapid and sustained learningLynette A Scherer
Department of Surgery, University of California, Davis, Sacramento, CA, USA
Am J Surg 185:516-20. 2003..Performance review using videotapes is a strategy employed to improve future performance. We postulated that videotape review of trauma resuscitations would improve compliance with a treatment algorithm... - External fixation or arteriogram in bleeding pelvic fracture: initial therapy guided by markers of arterial hemorrhagePreston R Miller
Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
J Trauma 54:437-43. 2003..Our aim was to evaluate markers of arterial bleeding in patients with BPF, thus identifying patients requiring early ANGIO regardless of fracture pattern... - Selective management of cardiovascular dysfunction in posttraumatic SIRS and sepsisR Shayn Martin
Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
Shock 23:202-8. 2005..Specific cardiovascular abnormalities can be identified at the bedside, and this information can guide pharmacologic management. Directed therapy improves cardiovascular function... - Complex blunt aortic injury or repair: beneficial effects of cardiopulmonary bypass usePreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27514, USA
Ann Surg 237:877-83; discussion 883-4. 2003..Special consideration is given to the influence of bypass in the outcome of complex injuries or repair circumstances... - A note on the disjointed nature of the injury severity scorePatrick D Kilgo
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
J Trauma 57:479-85; discussion 486-7. 2004..This study sought to compare the mortality of equivalent ISS values from different triplets and to evaluate whether ISS is a monotonic function of mortality... - Optimal threshold for diagnosis of ventilator-associated pneumonia using bronchoalveolar lavagePreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 55:263-7; discussion 267-8. 2003..In this project, the effects of lower diagnostic cutoffs on VAP diagnosis and unnecessary antibiotic use are examined... - Age thresholds for increased mortality of predominant crash induced thoracic injuriesJoel D Stitzel
Wake Forest University School of Medicine, Winston Salem, NC Virginia Tech Wake Forest University Center for Injury Biomechanics, Blacksburg, VA, Winston Salem, NC
Ann Adv Automot Med 54:41-50. 2010..Results of the current study and future work could lead to improvements in automotive safety design and regulation, automated crash notification, and hospital treatment for the elderly... - The pathogenesis of pulmonary contusion: an open chest model in the ratJ Jason Hoth
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 61:32-44; discussion 44-5. 2006..Herein we describe an open chest model of pulmonary contusion (PC) in a rodent (rat) and have identified a possible role for CC and CXC chemokines in the pathogenesis of PC... - Late fascial closure in lieu of ventral hernia: the next step in open abdomen managementPreston R Miller
Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27514, USA
J Trauma 53:843-9. 2002..We review a method of late primary fascial closure, thus eliminating the need for delayed reconstruction in some patients... - Trauma systems: improving trauma outcomes in North CarolinaRobert D Becher
Department of General Surgery, School of Medicine, Wake Forest University, Winston Salem, North Carolina, USA
N C Med J 71:574-8. 2010..This commentary reviews how the state has consistently decreased the burden of injury through its integrated, systems-based approach to trauma care... - Interventions-developing a plan for implementationJ Wayne Meredith
Wake Forest University School of Medicine, Department of Surgery, Winston-Salem, NC 27157, USA
J Trauma 59:S144-5; discussion S146-66. 2005 - The effectiveness of regionalized burn care: an analysis of 6,873 burn admissions in North Carolina from 2000 to 2007James H Holmes
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Am Coll Surg 212:487-93, 493.e1-6; discussion 493-5. 2011..The effectiveness and benefits of regionalized trauma care are well substantiated; however, the effectiveness of regionalized burn care and potential benefits of burn center verification have not been fully validated... - Elevated admission white blood cell count in pregnant trauma patients: an indicator of ongoing placental abruptionShuchi Shah
Department of General Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
Am Surg 68:644-7. 2002..Conversely WBC <20,000/mm3 rules out PA in the pregnant trauma patient (negative predictive value of 100%)... - The position of the Eastern Association for the Surgery of Trauma on the future of trauma surgeryMichael F Rotondo
Department of Surgery, East Carolina University, Brody School of Medicine, Greenville, North Carolina 27834, USA
J Trauma 59:77-9. 2005 - Improving ventricular-arterial coupling during resuscitation from shock: effects on cardiovascular function and systemic perfusionMichael C Chang
Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Trauma 53:679-85. 2002..Our hypothesis was that optimizing VAC during resuscitation results in improved myocardial work efficiency while simultaneously improving systemic perfusion... - The vacuum assisted closure device: a method of securing skin grafts and improving graft survivalLynette A Scherer
Department of Surgery, University of California Davis Medical Center, 2315 Stockton Blvd, Room 4209, Sacramento, CA 95817, USA
Arch Surg 137:930-3; discussion 933-4. 2002..Use of the vacuum assisted closure device (VAC) for securing split-thickness skin grafts (STSGs) is associated with improved wound outcomes compared with bolster dressings... - The effect of burn nursing units on burn wound infectionsJames T Thompson
Winston Salem, North Carolina 27157-1075, USA
J Burn Care Rehabil 23:281-6; discussion 280. 2002..Despite consistent wound care the incidence of infection increased nearly two-fold to four-fold when patients were treated out of the unit. We recommend a temporary isolation unit during renovations if possible... - Incorporating recent advances to make the TRISS approach universally availablePatrick D Kilgo
Department of Biostatistics, Emory University School of Public Health, GA 30322, USA
J Trauma 60:1002-8; discussion 1008-9. 2006..This study hypothesized that the TRISS approach could be made more predictive and efficient with fewer variables by incorporating these advances... - Evidence of beneficial effect of physical therapy after lower-extremity traumaRenan C Castillo
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Arch Phys Med Rehabil 89:1873-9. 2008..To examine the effect of physical therapy (PT) use on a range of measures of physical impairment in a cohort of patients with lower-extremity trauma... - The state of US trauma systems: public perceptions versus reality--implications for US response to terrorism and mass casualty eventsHoward R Champion
Coalition for American Trauma Care, Reston VA, USA
J Am Coll Surg 203:951-61. 2006..Trauma systems must be adequately developed and supported to fulfill the public's expectation to receive the best possible care if seriously injured, and to ensure readiness for mass casualty and terrorist incidents...