Research Topics
| Joseph MaldjianSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Fully automated processing of fMRI data in SPM: from MRI scanner to PACSJoseph A Maldjian
Wake Forest University, Winston Salem, NC, USA
Neuroinformatics 7:57-72. 2009..The pipeline requires no manual intervention, and can be extended to any studies requiring offline processing...
Differences in carotid arterial morphology and composition between individuals with and without obstructive coronary artery disease: a cardiovascular magnetic resonance studyHunter R Underhill
Department of Radiology University of Washington, Seattle, WA, USA
J Cardiovasc Magn Reson 10:31. 2008....
Cross-modal deactivations during modality-specific selective attentionJennifer L Mozolic
Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
BMC Neurol 8:35. 2008..This study was designed to determine how focusing attention on the auditory or visual modality impacts neural activity in cortical regions responsible for processing stimuli in the unattended modality...
Clinical implementation of spin-tag perfusion magnetic resonance imagingJoseph A Maldjian
Department of Radiology, Wake Forest University Medical School, Medical Center Boulevard, Winston Salem, NC, USA
J Comput Assist Tomogr 32:403-6. 2008..Here, we describe a fully automated pipeline for clinical implementation of a magnetic resonance spin-tag perfusion sequence that can be extended to any studies requiring off-line processing...
Precentral gyrus discrepancy in electronic versions of the Talairach atlasJoseph A Maldjian
Department of Radiology, Wake Forest University Health Sciences Center, Winston Salem, NC 27157, USA
Neuroimage 21:450-5. 2004..The mislabeled portion encompasses a 3 x 1.5-cm region in the axial plane and has significant implications for sensorimotor studies that rely on the digital atlases for anatomic labeling...
An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data setsJoseph A Maldjian
Department of Radiology, Wake Forest University Health Sciences Center, Winston Salem, NC 27157, USA
Neuroimage 19:1233-9. 2003..This tool represents a necessary evolution in fMRI data analysis for testing of more spatially complex hypotheses...
Relationship between caffeine-induced changes in resting cerebral perfusion and blood oxygenation level-dependent signalPaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
AJNR Am J Neuroradiol 24:1607-11. 2003..Future studies aimed at evaluating the relationship between perfusion and BOLD signal intensity changes should seek a means to selectively modulate known components of the neural and vascular responses independently...
Dietary caffeine consumption modulates fMRI measuresPaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1022, USA
Neuroimage 17:751-7. 2002..We propose that the outcome observed here was due to an upregulation of adenosine receptors in high users, resulting in differential contributions of the neural and vascular effects of adenosine in the two study populations...
Arterial transit time imaging with flow encoding arterial spin tagging (FEAST)Jiongjiong Wang
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Magn Reson Med 50:599-607. 2003..Application of the FEAST technique in two patients with cerebrovascular disease demonstrated prolonged tissue transit times in the affected vascular territories which were consistent with results from other MR imaging modalities...
The impact of temporal regularization on estimates of the BOLD hemodynamic response function: a comparative analysisRamon Casanova
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC, USA
Neuroimage 40:1606-18. 2008..Our results clarify the effects of temporal resolution, noise color, and experimental design on the accuracy of HRF estimation...
Arterial spin-labeled magnetic resonance imaging in hyperperfused seizure focus: a case reportJeffrey M Pollock
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC, USA
J Comput Assist Tomogr 32:291-2. 2008..The finding of hyperperfusion with perfusion imaging significantly impacted clinical management of the patient...
Closing the mind's eye: deactivation of visual cortex related to auditory task difficultyW David Hairston
ANSIR Lab, Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27257, USA
Neuroreport 19:151-4. 2008..Together, these results suggest that cross-modal deactivations occur in compensation for task difficulty, perhaps acting as an intrinsic filter for nonrelevant information...
Brain volumes, cognitive impairment, and conjugated equine estrogensMark A Espeland
Department of Biostatistical Sciences, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 64:1243-50. 2009....
An adaptive staircase procedure for the E-Prime programming environmentW David Hairston
Human Research and Engineering Directorate, US Army Research Laboratory, Aberdeen Proving Ground, MD 21005, USA
Comput Methods Programs Biomed 93:104-8. 2009..An example experiment (visual temporal-order-judgment task) where subjects report the order of occurrence of two circles illustrates the behavior and consistency of the routine...
A fast, effective filtering method for improving clinical pulsed arterial spin labeling MRIHuan Tan
Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Magn Reson Imaging 29:1134-9. 2009..To evaluate the effectiveness of a fully automated postprocessing filter algorithm in pulsed arterial spin labeling (PASL) MRI perfusion images in a large clinical population...
Aging and the interaction of sensory cortical function and structureAnn M Peiffer
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Hum Brain Mapp 30:228-40. 2009..Thus, functional differences in cortical activity between older and younger adults cannot solely be accounted for by differences in gray matter volume...
Relating imaging indices of white matter integrity and volume in healthy older adultsChristina E Hugenschmidt
Neuroscience Program, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Cereb Cortex 18:433-42. 2008..As such, the ability to detect early white matter alterations may facilitate development of targeted treatments that prevent or slow age-related white matter degradation and associated cognitive sequelae...
Cross-modal sensory processing in the anterior cingulate and medial prefrontal corticesPaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Hum Brain Mapp 19:213-23. 2003..Although activity in these regions was also dependent on task difficulty, showing decreased activity with decreasing task difficulty, the activity changes associated with stimulus congruence predominated...
Separating neural processes using mixed event-related and epoch-based fMRI paradigmsPaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1022, USA
J Neurosci Methods 131:41-50. 2003..Mixed designs provide neuroscientists with the power and flexibility to address more complex cognitive hypotheses that were otherwise difficult to study with either epoch-based or event-related designs alone...
Semantic congruence is a critical factor in multisensory behavioral performancePaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Exp Brain Res 158:405-14. 2004....
Enhanced multisensory integration in older adultsPaul J Laurienti
Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Neurobiol Aging 27:1155-63. 2006..e., visual). The current results suggest that despite the decline in sensory processing that accompanies aging, the use of multiple sensory channels may represent an effective compensatory strategy to overcome these unisensory deficits...
Biological parametric mapping: A statistical toolbox for multimodality brain image analysisRamon Casanova
Advanced Neuroscience Imaging Research ANSIR Laboratory, Department of Radiology, Wake Forest University School of Medicine, USA
Neuroimage 34:137-43. 2007..An example with in vivo data is presented, demonstrating the potential of the BPM methodology as a tool for multimodal image analysis...
Continuous arterial spin labeled perfusion magnetic resonance imaging in patients before and after carotid endarterectomyBeau M Ances
Department of Neurology, Department of Neurosurgery, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
J Neuroimaging 14:133-8. 2004..78, P < .05) but not in the posterior distribution (r = .25, P = .63). CASL-pMRI may provide a convenient, inexpensive, noninvasive method for identifying CEA patients at risk for hyperperfusion following carotid revascularization...
The effect of daily caffeine use on cerebral blood flow: How much caffeine can we tolerate?Merideth A Addicott
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Hum Brain Mapp 30:3102-14. 2009..Our results suggest a limited ability of the cerebrovascular adenosine system to compensate for high amounts of daily caffeine use...
Arterial spin-labeled MR perfusion imaging: clinical applicationsJeffrey M Pollock
Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Magn Reson Imaging Clin N Am 17:315-38. 2009..The appearance of pathology is affected significantly by the ASL techniques used. Familiarity with the available sequence parameter options and the common appearances of pathology facilitates perfusion interpretation...
Multiple reproducibility indices for evaluation of cognitive functional MR imaging paradigmsJoseph A Maldjian
Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
AJNR Am J Neuroradiol 23:1030-7. 2002..The forward-backward paradigm demonstrates more focal activations with less extraneous activation...
Multicenter, double-blind, randomized, intra-individual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine in MRI of brain tumors at 3 teslaZoran Rumboldt
Medical University of South Carolina, Department of Radiology, Charleston, SC, USA
J Magn Reson Imaging 29:760-7. 2009..To prospectively compare 0.1 mmol/kg doses of gadobenate dimeglumine and gadopentetate dimeglumine for contrast-enhanced MRI of brain lesions at 3 Tesla (T)...
Susceptibility contrast and arterial spin labeled perfusion MRI in cerebrovascular diseaseRonald L Wolf
Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA
J Neuroimaging 13:17-27. 2003....
Integrating postprocessed functional MR images with picture archiving and communication systemsJoseph A Maldjian
Department of Radiology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA
AJNR Am J Neuroradiol 23:1393-7. 2002..The procedure can be used with any MR postprocessed dataset, and it can be extended to other imaging modalities...
Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patientsTeresa R Franklin
Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA 19104-6178, USA
Biol Psychiatry 51:134-42. 2002....
Research Grants
- Uncovering Brain Anatomy/Function/Relationships using Biologic Parametric MappingJoseph Maldjian; Fiscal Year: 2005....
- Cerberal Diffusion and Perfusion Correlation using Biologic Parametric MappingJoseph Maldjian; Fiscal Year: 2005....
- Integrated Tool for Biological Parametric MappingJoseph Maldjian; Fiscal Year: 2007....
