M J Loza

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Association between Q551R IL4R genetic variants and atopic asthma risk demonstrated by meta-analysis
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Allergy Clin Immunol 120:578-85. 2007
  2. ncbi NKT and T cells: coordinate regulation of NK-like phenotype and cytokine production
    Matthew J Loza
    Jefferson Medical College, Kimmel Cancer Center, Department of Microbiology and Immunology, Philadelphia, PA, USA
    Eur J Immunol 32:3453-62. 2002
  3. ncbi Assembly of inflammation-related genes for pathway-focused genetic analysis
    Matthew J Loza
    Center for Human Genomics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, United States of America
    PLoS ONE 2:e1035. 2007
  4. ncbi Interactive effects of steroids and beta-agonists on accumulation of type 2 T cells
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Allergy Clin Immunol 121:750.e1-5.e3. 2008
  5. ncbi Asthma and gender impact accumulation of T cell subtypes
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Respir Res 11:103. 2010
  6. ncbi Atopy, asthma, and experimental approaches based on the linear model of T cell maturation
    M J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Clin Exp Allergy 35:8-17. 2005
  7. ncbi Peripheral immature CD2-/low T cell development from type 2 to type 1 cytokine production
    Matthew J Loza
    Kimmel Cancer Center, Department of Microbiology and Immunology, Jefferson Medical College, Philadelphia, PA 19107, USA
    J Immunol 169:3061-8. 2002
  8. ncbi Expression of type 1 (interferon gamma) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells
    Matthew J Loza
    The Kimmel Cancer Center, Jefferson Medical College, Philadelphia, PA 19107, USA
    Blood 99:1273-81. 2002
  9. ncbi beta-Agonist enhances type 2 T-cell survival and accumulation
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Allergy Clin Immunol 119:235-44. 2007
  10. ncbi Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA
    Blood 107:2052-60. 2006

Detail Information

Publications18

  1. ncbi Association between Q551R IL4R genetic variants and atopic asthma risk demonstrated by meta-analysis
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Allergy Clin Immunol 120:578-85. 2007
    ..However, the results from studies testing for associations of the I50V and Q551R IL4R genetic variants are conflicting...
  2. ncbi NKT and T cells: coordinate regulation of NK-like phenotype and cytokine production
    Matthew J Loza
    Jefferson Medical College, Kimmel Cancer Center, Department of Microbiology and Immunology, Philadelphia, PA, USA
    Eur J Immunol 32:3453-62. 2002
    ..However, the results of their analysis can be taken as a model for immunotherapeutic approaches with T cells for which a nominal or surrogate antigen is defined...
  3. ncbi Assembly of inflammation-related genes for pathway-focused genetic analysis
    Matthew J Loza
    Center for Human Genomics, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, United States of America
    PLoS ONE 2:e1035. 2007
    ..For existing genome-wide association data, this list of key inflammation-related genes and associated subpathways can facilitate comprehensive inflammation pathway- focused association analyses...
  4. ncbi Interactive effects of steroids and beta-agonists on accumulation of type 2 T cells
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Allergy Clin Immunol 121:750.e1-5.e3. 2008
    ....
  5. ncbi Asthma and gender impact accumulation of T cell subtypes
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Respir Res 11:103. 2010
    ..We sought to establish whether CD3+CD28-mediated and antigen-independent accumulation of type 1 and type 2 T cells differs significantly between nonasthmatic and asthmatic populations...
  6. ncbi Atopy, asthma, and experimental approaches based on the linear model of T cell maturation
    M J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Clin Exp Allergy 35:8-17. 2005
    ....
  7. ncbi Peripheral immature CD2-/low T cell development from type 2 to type 1 cytokine production
    Matthew J Loza
    Kimmel Cancer Center, Department of Microbiology and Immunology, Jefferson Medical College, Philadelphia, PA 19107, USA
    J Immunol 169:3061-8. 2002
    ..They define the cellular bases to support that cell-mediated immune responses are regulated not only via Ag-induced activation of mature effector cells, but also via bystander monokine-induced maturation of immature T cells...
  8. ncbi Expression of type 1 (interferon gamma) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells
    Matthew J Loza
    The Kimmel Cancer Center, Jefferson Medical College, Philadelphia, PA 19107, USA
    Blood 99:1273-81. 2002
    ....
  9. ncbi beta-Agonist enhances type 2 T-cell survival and accumulation
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Allergy Clin Immunol 119:235-44. 2007
    ..beta-Adrenergic receptor ligands (beta-agonists) subserve numerous physiologic processes but also function as pathogenic or therapeutic agents in numerous diseases with inflammatory components...
  10. ncbi Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells
    Matthew J Loza
    Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA
    Blood 107:2052-60. 2006
    ..These findings identify direct effects of beta2AR activation on T-cell subtypes and suggest a complex role for GPCRs and PKA activity in modulating T-cell functions...
  11. ncbi Human peripheral CD2-/lo T cells: an extrathymic population of early differentiated, developing T cells
    Matthew J Loza
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, Thomas Jefferson University, BLSB 750, 233 South, 10th Street, Philadelphia, PA 19107, USA
    Int Immunol 17:1213-25. 2005
    ....
  12. ncbi Peripheral NK cell phenotypes: multiple changing of faces of an adapting, developing cell
    Bice Perussia
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, Philadelphia, PA 19107, USA
    Mol Immunol 42:385-95. 2005
    ....
  13. ncbi The IL-12 signature: NK cell terminal CD56+high stage and effector functions
    Matthew J Loza
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, 233 South 10th Street, Philadelphia, PA 19107, USA
    J Immunol 172:88-96. 2004
    ..The significance of these findings to the NK cell-mediated regulation of immune responses and NK cell development is discussed...
  14. ncbi Differential regulation of NK cell proliferation by type I and type II IFN
    Matthew J Loza
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, Philadelphia, PA 19107, USA
    Int Immunol 16:23-32. 2004
    ....
  15. ncbi Linear "2-0-1" lymphocyte development: hypotheses on cellular bases for immunity
    Bice Perussia
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, BLSB 750, 233 S. 10th Street, Philadelphia, PA 19107, USA
    Trends Immunol 24:235-41. 2003
  16. ncbi Accumulation of type 2 cytokine+ T cells: differentiation-independent proliferation of pre-existing type 2 T cells
    Matthew J Loza
    Jefferson Medical College, Kimmel Cancer Center, Department of Microbiology and Immunology, Philadelphia, USA
    Eur J Immunol 33:939-49. 2003
    ..These novel insights into the regulation of type 2 and type 1 cytokine(+) T cells provide a new understanding of the cellular bases for the regulation of immune responses and for manipulating the immune system in clinical settings...
  17. ncbi Multiple color immunofluorescence for cytokine detection at the single-cell level
    Matthew J Loza
    Bice Perussia, Jefferson Medical College, Kimmel Cancer Institute, Philadelphia, PA 19107, USA
    Mol Biotechnol 23:245-58. 2003
    ....
  18. ncbi Distinction between IL-13+ and IFN-gamma+ natural killer cells and regulation of their pool size by IL-4
    Matthew J Loza
    Department of Microbiology and Immunology, Kimmel Cancer Center, Jefferson Medical College, 233 S. 10th Street, Philadelphia, PA 19107, USA
    Eur J Immunol 32:413-23. 2002
    ..These data define the existence and regulation of two distinct resting peripheral NK cell subsets producing type 1 and type 2 cytokines, and suggest possible roles for IL-13+ NK cells in allergy...