Research Topics
| L A KomanSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Surgery of the upper extremity in cerebral palsyL Andrew Koman
Department of Orthopedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Orthop Clin North Am 41:519-29. 2010..In addition, the various evaluation techniques of the upper extremity, the general principles of an operative treatment plan, and the appropriate postoperative care of these patients is presented...
Cerebral palsyL Andrew Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157 1070, USA
Lancet 363:1619-31. 2004..This seminar addresses only the musculoskeletal issues associated with cerebral palsy and only indirectly discusses the cognitive, medical, and social issues associated with this diagnosis...- Botulinum toxin type a neuromuscular blockade in the treatment of equinus foot deformity in cerebral palsy: a multicenter, open-label clinical trialL A Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1070, USA
Pediatrics 108:1062-71. 2001..Focal spasticity of the gastrocnemius-soleus muscles causes equinus gait in children with cerebral palsy (CP). Botulinum toxin type A (BTX-A), a neuromuscular blocking agent, reduces muscle tone/overactivity in dystonia, stroke, and CP... - Spasticity associated with cerebral palsy in children: guidelines for the use of botulinum A toxinL Andrew Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1070, USA
Paediatr Drugs 5:11-23. 2003..Botulinum A toxin, when used in appropriate doses, is well tolerated... - Botulinum toxin type A neuromuscular blockade in the treatment of lower extremity spasticity in cerebral palsy: a randomized, double-blind, placebo-controlled trial. BOTOX Study GroupL A Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1070, USA
J Pediatr Orthop 20:108-15. 2000..Patients in the BTX group demonstrated improved gait function and partial denervation of the injected muscle. No serious adverse events were reported... - The effect of transdermal nicotine on digital perfusion in reformed habitual smokersS M Fulcher
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Hand Surg Am 23:792-9. 1998.... - Arterial reconstruction in the ischemic hand and wrist: effects on microvascular physiology and health-related quality of lifeL A Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157 1070, USA
J Hand Surg Am 23:773-82. 1998..Although cold sensitivity was unchanged, symptoms decreased and upper extremity function and health-related quality of life improved after successful proximal reconstruction in patients with 2-level arterial occlusion... - The role of hip arthroscopy in the evaluation of avascular necrosisD S Ruch
Department of Orthopedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1070, USA
Orthopedics 24:339-43. 2001..Arthroscopy of the hip revealed osteochondral degeneration that was not detected by plain radiographs or MRI in 36% of post-collapse femoral heads... - Complex regional pain syndrome (reflex sympathetic dystrophy)Robert D Teasdall
Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Clin Sports Med 23:145-55. 2004..Therapeutic efforts that should be effective may fail, and a trial-and-error approach to treatment is often mandatory. Early recognition of CRPS and prompt intervention, however, provide the best opportunity for clinical improvement... - Safety profile of multilevel chemical denervation procedures using phenol or botulinum toxin or both in a pediatric populationKat Kolaski
Department of Orthopaedic Surgery, Wake Forest University Health Sciences, Winston Salem, NC 27103, USA
Am J Phys Med Rehabil 87:556-66. 2008..To investigate the safety of single and repeated multilevel injections of botulinum toxin (BoNT) alone or a combination of phenol and BoNT performed under general anesthesia in children with chronic muscle spasticity... - Brachial plexus birth palsy-associated shoulder deformity: a rat model studyZhongyu Li
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Hand Surg Am 33:308-12. 2008..The aim of this study was to establish an animal model to study BPBP-associated shoulder deformities... - Quantifying spasticity in a clinical settingJames A Norris
School of Biomedical Engineering and Sciences, Wake Forest Virginia Tech, Winston Salem, NC 27157 1022, USA
Biomed Sci Instrum 43:284-9. 2007..Three clinical cases are presented. These preliminary examples from the clinic suggest that this technique provides an improved method to monitor spasticity... - Neuromuscular recovery after distraction osteogenesis at different frequencies in a rabbit modelCassandra Lee
Department of Orthopaedic Surgery, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA
J Pediatr Orthop 26:628-33. 2006..Repeated microtrauma to the soft tissues associated with high-frequency distraction may facilitate the regenerative capacity of the soft tissues and result in an improved outcome of muscle and nerve function... - Vascular changes of the hand in professional baseball players with emphasis on digital ischemia in catchersT Adam Ginn
Department of Orthopaedic Surgery, Extremity Laboratory, Wake Forest University Baptist Medical Center, Medical Center Boulevard, 4th Floor, Watlington Hall, Winston Salem, NC 27157, USA
J Bone Joint Surg Am 87:1464-9. 2005..In contrast to previous investigators, we documented the presence of abnormalities in younger, asymptomatic individuals... - Longitudinal examination of health outcomes associated with botulinum toxin use in children with cerebral palsyRajesh Balkrishnan
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
J Surg Orthop Adv 13:76-80. 2004..001). These findings suggest that BTX injections may be associated with beneficial outcomes in childhood spasticity... - Management of peripheral nerve defects: external fixator-assisted primary neurorrhaphyDavid S Ruch
Department of Orthopaedic Surgery, Watlington Hall, 4th Floor, Medical Center Boulevard, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Bone Joint Surg Am 86:1405-13. 2004..The hypothesis of the present study was that gradual lengthening of nerve repairs with use of incremental distraction would provide superior results compared with grafting or repair under tension... - Pharmacologic management of spasticity in cerebral palsyJames F Mooney
Department of Orthopaedic Surgery, Children's Hospital of Michigan, Detroit, Michigan 48201, USA
J Pediatr Orthop 23:679-86. 2003 - Stress and adaptation in mothers of children with cerebral palsyJaneen Manuel
Wake Forest University School of Medicine, Department of Public Health Sciences, Winstion Salem, NC 27157, USA
J Pediatr Psychol 28:197-201. 2003.... - The pink pulseless handDavid Simms Ruch
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1070, USA
J South Orthop Assoc 11:174-8. 2002..Review of the literature is included, as well as recommendations regarding operative management... - Periarterial sympathectomy in scleroderma patients: intermediate-term follow-upDavid S Ruch
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1070, USA
J Hand Surg [Am] 27:258-64. 2002..Follow-up of scleroderma patients after PAS documented improved microvascular perfusion as evaluated by laser Doppler fluxmetry and by variable clinical results... - Factors associated with self-esteem in pre-adolescents and adolescents with cerebral palsyJaneen C Manuel
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157, USA
J Adolesc Health 32:456-8. 2003..In a multivariate model, only perceived impact of the disability remained significant... - Juvenile and adult rat neuromuscular junctions: density, distribution, and morphologyJianjun Ma
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, 4th Floor, Watlington Hall, Medical Center Blvd, Winston-Salem, North Carolina 27157, USA
Muscle Nerve 26:804-9. 2002.... - Post-traumatic ulnar artery thrombosis: outcome of arterial reconstruction using reverse interpositional vein grafting at 2 years minimum follow-upGeorge D Chloros
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Hand Surg Am 33:932-40. 2008..This study reports the outcome at 2 years minimum follow-up of a uniform approach using reversed interpositional vein grafting to treat symptomatic patients with UAT... - Bioprotection of tendon repair: adjunctive use of botulinum toxin A in Achilles tendon repair in the ratJianjun Ma
Department of Orthopaedic Surgery, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
J Bone Joint Surg Am 89:2241-9. 2007.... - Digital ischemia due to essential thrombocythemia: a case reportAnastasios Papadonikolakis
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Hand Surg Am 32:1053-7. 2007..This report describes the case of a 34-year-old patient with essential thrombocythemia who presented with Raynaud's syndrome, was refractory to medical treatment, and developed progressive digital gangrene... - Effects of Botox and Neuronox on muscle force generation in miceAustin V Stone
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
J Orthop Res 25:1658-64. 2007.... - The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nervesPaulina Sierpinski
The Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Biomaterials 29:118-28. 2008..These results suggest that a biomaterial derived from human hair keratins is neuroinductive and can facilitate an outcome comparable to autograft in a nerve injury model... - Recurrence of equinus foot deformity in cerebral palsy patients following surgery: a reviewL Andrew Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1070, USA
J South Orthop Assoc 12:125-33, quiz 134. 2003..One study demonstrated that the use of chemodenervation delayed surgery and by inference theoretically would decrease recurrence after surgical release... - How muscles recover from paresis and atrophy after intramuscular injection of botulinum toxin A: Study in juvenile ratsJian Shen
Department of Orthopaedic Surgery, Wake Forest University Medical Center, Winston-Salem, North Carolina 27104, USA
J Orthop Res 24:1128-35. 2006..This recovery process is divided into two stages (aneural and neural) and that the IGF-1 signaling pathway play a central role in the process... - Cost impact of botulinum toxin use in Medicaid-enrolled children with cerebral palsyRajesh Balkrishnan
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
J South Orthop Assoc 11:71-9. 2002..These data suggest that BTX therapy does not significantly add to the costs of treating Medicaid-enrolled children with CP... - Gene expression of myogenic regulatory factors following intramuscular injection of botulinum A toxin in juvenile ratsJian Shen
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA
Neurosci Lett 381:207-10. 2005 - Time course of recovery of juvenile skeletal muscle after botulinum toxin A injection: an animal model studyJianjun Ma
Department of Orthopaedic Surgery, Wake Forest University Health Sciences, Winston-Salem, North Carolina 27157, USA
Am J Phys Med Rehabil 83:774-80; quiz 781-3. 2004..CONCLUSION: Our findings provide scientific evidence to support the clinical situation in which the interinjection interval of 3-6 mos of botulinum toxin A at a similar dosage is used... - Cerebral palsy: past, present, and futureL Andrew Koman
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1070, USA
J South Orthop Assoc 11:93-101. 2002 - The acute effect of peripheral nerve transection on digital thermoregulatory functionDavid S Ruch
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
J Hand Surg [Am] 28:481-8. 2003..CONCLUSIONS: This study documents that cutaneous perfusion and thermoregulatory function is altered after isolated peripheral nerve injury... - Clinical usefulness of botulinum toxin in the lower extremityLaura K Jacks
Children s Orthopaedics of Louisville, 3900 Kresge Way, Suite 52, Louisville, KY 40241, USA
Foot Ankle Clin 9:339-48. 2004..We review the uses and techniques for botulinum toxin in the foot and ankle and present results of botulinum toxin treatment in 10 idiopathic toe walkers... - Technique for iliopsoas ultrasound-guided active electromyography-directed botulinum a toxin injection in cerebral palsyMichael J Willenborg
Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA
J Pediatr Orthop 22:165-8. 2002..The authors' experience to date includes the treatment of 28 patients (53 hips). Use of this technique has resulted in improved hip range of motion. No intraoperative or postoperative adverse events or complications have been observed... - Parent caregiver-related predictors of health care service utilization by children with cerebral palsy enrolled in MedicaidRajesh Balkrishnan
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
J Pediatr Health Care 16:73-8. 2002..Parents who believed that their children receive enough care may need to be targeted for care management and disease management programs to ensure the continuum of treatment and care for these children...