Annette T Hastie
Affiliation: Wake Forest University School of Medicine
- Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and beta2-agonist useAnnette T Hastie
Department of Internal Medicine, Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
Respir Res 7:25. 2006....
- Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytesAnnette T Hastie
Center for Human Genomics, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
J Allergy Clin Immunol 125:1028-1036.e13. 2010..Patients with severe asthma have increased granulocytes in their sputum compared with patients with mild to moderate asthma...
- Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjectsAnnette T Hastie
Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
J Allergy Clin Immunol 132:72-80. 2013..Availability and ease of measurement are useful characteristics, but accuracy in predicting airway eosinophil and neutrophil percentages either individually or combined is not established...
- The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthmaGregory A Hawkins
Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
J Allergy Clin Immunol 130:510-5.e1. 2012..The SNP rs4129267 is in linkage disequilibrium (r(2) = 1) with the IL6R coding SNP rs2228145 (Asp(358)Ala). This IL6R coding change increases IL-6 receptor (IL-6R) shedding and promotes IL-6 transsignaling...
- Modulation of vasodilator-stimulated phosphoprotein in vivo in human epithelial cells by segmental allergen challenge and beta2-agonist therapyAnnette T Hastie
Thomas Jefferson University, Philadelphia, PA 19107, USA
Chest 123:377S. 2003
- Asthmatic epithelial cell proliferation and stimulation of collagen production: human asthmatic epithelial cells stimulate collagen type III production by human lung myofibroblasts after segmental allergen challengeAnnette T Hastie
Department of Medicine, Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, and Division of Clinical Pharmacology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania
Am J Respir Crit Care Med 165:266-72. 2002..Epithelial cell proliferation appears dependent upon infiltrating inflammatory cells, but stimulation of collagen type III does not...
- Concentration of cytokines and growth factors in BAL fluid after allergen challenge in asthmatics and their effect on alpha-smooth muscle actin and collagen III synthesis by human lung fibroblastsVikas Batra
Thomas Jefferson University, Philadelphia, PA, USA
Chest 123:398S-9S. 2003