Research Topics
| C D FurbergSummaryAffiliation: Wake Forest University School of Medicine Country: USA Publications
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Publications
Subgroup interactions in the Heart and Estrogen/Progestin Replacement Study: lessons learnedCurt D Furberg
Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Circulation 105:917-22. 2002..We analyzed the HERS data to determine whether there were specific subgroups of women who responded differently to treatment, either during the first year or in the overall study...
Approaches to data analyses of clinical trialsCurt D Furberg
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Prog Cardiovasc Dis 54:330-4. 2012..four questions related to secondary analysis with emphasis on sharing of data primarily from NIH-sponsored trials: Who has access to this information? What questions can be asked? What are the requirements? What are the common challenges?..
Five years of TrialsDouglas G Altman
Centre for Statistics in Medicine, Wolfson College Annexe, Linton Road, Oxford OX2 6UD, UK
Trials 12:248. 2011..These include the publication of raw data, extended versions of previously published trial-related articles, descriptions of 'lessons learned', negative results, and educational articles regarding ethics and reporting bias...
A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health OrganizationElsayed Z Soliman
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Trials 12:3. 2011..More information is needed regarding the efficacy in reducing the risk factors of cardiovascular disease (CVD), side effects, improvement in adherence and physician/patient "acceptability" of the Polypill...
[Reduce prescription of expensive drugs without increased value]Curt Furberg
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, USA
Lakartidningen 100:4113. 2003
[Alfadil--positive documentation when it comes to safety is missing]Curt Furberg
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, USA
Lakartidningen 100:4329; discussion 4330. 2003
Doxazosin, an inferior antihypertensive agent?C D Furberg
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
J Hum Hypertens 16:375-7. 2002
To whom do the research findings apply?Curt D Furberg
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
Heart 87:570-4. 2002
The FDA and drug safety: a proposal for sweeping changesCurt D Furberg
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Arch Intern Med 166:1938-42. 2006....
Distribution and correlates of lipoprotein-associated phospholipase A2 in an elderly cohort: the Cardiovascular Health StudyCurt D Furberg
Division of Public Health Sciences, School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157 1063, USA
J Am Geriatr Soc 56:792-9. 2008....
Double-blindness protects scientific validityC D Furberg
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1063, USA
J Thromb Haemost 6:230-1. 2008
Are all angiotensin-converting enzyme inhibitors interchangeable?C D Furberg
Department of Public Health Sciences, Wake Forest University, Winston Salem, North Carolina 27157, USA
J Am Coll Cardiol 37:1456-60. 2001..For our patients, such practice is a legitimate expectation. Therefore, it seems prudent to recommend that patients requiring ACE inhibitor therapy be prescribed one that has been proven effective and safe...
Should evidence-based proof of drug efficacy be extrapolated to a "class of agents"?Curt D Furberg
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1063, USA
Circulation 108:2608-10. 2003
Isradipine in prediabetic hypertensive subjectsR P Byington
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1063, USA
Diabetes Care 21:2103-10. 1998....
Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetesM Pahor
Sticht Center on Aging, Department of Internal Medicine, Wake Forest University, Winston Salem, North Carolina 27157, USA
Diabetes Care 23:888-92. 2000..To assess whether ACE inhibitors are superior to alternative agents for the prevention of cardiovascular events in patients with hypertension and type 2 diabetes...
Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trialsM Pahor
Sticht Center on Aging, Department of Internal Medicine, Wake Forest University, Winston Salem, NC 27157, USA
Lancet 356:1949-54. 2000..The aim of this meta-analysis was to compare the effects of calcium antagonists and other antihypertensive drugs on major cardiovascular events...
Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trialsDavid L Mount
Wake Forest University School of Medicine, Winston Salem, NC, USA
Clin Trials 6:416-29. 2009..Comparing findings from separate trials is necessary to choose among treatment options, however differences among study cohorts may impede these comparisons...
Usefulness of T-axis deviation as an independent risk indicator for incident cardiac events in older men and women free from coronary heart disease (the Cardiovascular Health Study)P M Rautaharju
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Am J Cardiol 88:118-23. 2001..These results suggest that T-axis deviation is an easily quantified marker for subclinical disease and an independent indicator for the risk of incident CHD events in older men and women free of CHD...
Clinical Implications of Recent Findings from the Antihypertensive and Lipid-Lowering Treatment To Prevent Heart Attack Trial (ALLHAT) and Other Studies of HypertensionC D Furberg
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
Ann Intern Med 135:1074-8. 2001....
Assessment of temporal bias in longitudinal measurements of carotid intimal-medial thickness in the Asymptomatic Carotid Artery Progression Study (ACAPS). ACAPS Research GroupW A Riley
Department of Neurology, Bowman Gray School of Medicine, Wake Forest University, Winston Salem, NC 27157 1078, USA
Ultrasound Med Biol 22:405-11. 1996..The carotid IMT measurement process, when combined with uniform reader training, certification and monitoring of reading performance throughout the course of the study, can avoid the temporal bias observed in other studies...
Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysisSonal Singh
Department of Medicine, One Medical Center Blvd, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 300:1439-50. 2008..Inhaled anticholinergics (ipratropium bromide or tiotropium bromide) are widely used in patients with chronic obstructive pulmonary disease (COPD) but their effect on the risk of cardiovascular outcomes is unknown...
Long-term risk of cardiovascular events with rosiglitazone: a meta-analysisSonal Singh
Department of Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 298:1189-95. 2007..Recent reports of serious adverse events with rosiglitazone use have raised questions about whether the evidence of harm justifies its use for treatment of type 2 diabetes...
Thiazolidinediones and heart failure: a teleo-analysisSonal Singh
Section of General Internal Medicine, Wake Forest University School of Medicine, 1 Medical Center Blvd, Winston Salem, NC 27157, USA
Diabetes Care 30:2148-53. 2007..We aimed to evaluate the magnitude of the risk of heart failure with TZDs and classify this adverse effect under the novel dose-time-susceptibility system...
Effect of estrogen plus progestin on progression of carotid atherosclerosis in postmenopausal women with heart disease: HERS B-mode substudyRobert P Byington
Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Arterioscler Thromb Vasc Biol 22:1692-7. 2002..In addition to the events trial, a carotid ultrasound substudy was established in 1993 to be conducted concurrently to determine whether hormone therapy affects the progression of the underlying atherosclerotic process...
Effect of Ginkgo biloba on blood pressure and incidence of hypertension in elderly men and womenTina E Brinkley
Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Am J Hypertens 23:528-33. 2010..Accumulating evidence suggests that Ginkgo biloba is cardioprotective, in part, through its vasodilatory and antihypertensive properties. However, definitive data on its blood pressure (BP)-lowering effects in humans is lacking...
Controlling prescription drug expenditures: a report of successDavid P Miller
General Internal Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Am J Manag Care 13:473-80. 2007..To determine whether a multi-interventional program can limit increases in prescription drug expenditures while maintaining utilization of needed medications...
Cost-minimization and the number needed to treat in uncomplicated hypertensionK A Pearce
Department of Family and Community Medicine, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27012, USA
Am J Hypertens 11:618-29. 1998..Treatment costs to prevent major hypertensive complications are much lower with diuretics and beta-blockers than with ACEI, CCB, or alpha-blockers, especially in middle-aged patients...
Developing an optimal approach to global drug safetyR Balkrishnan
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Intern Med 250:271-9. 2001..This report summarizes the resulting discussions of global postmarketing surveillance initiatives and describes efforts to reduce medication errors, and improve global communication about drug safety...
Effects of lovastatin and warfarin on early carotid atherosclerosis: sex-specific analyses. Asymptomatic Carotid Artery Progression Study (ACAPS) Research GroupR P Byington
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Circulation 100:e14-7. 1999..Few clinical trials have documented the efficacy of preventive treatment in asymptomatic women...
Comparison of mortality risk for electrocardiographic abnormalities in men and women with and without coronary heart disease (from the Cardiovascular Health Study)Pentti M Rautaharju
the Department of Public Health Sciences, Wake Forest University, Winston Salem, North Carolina, USA
Am J Cardiol 97:309-15. 2006..In conclusion, we found no evidence that the relative risk of mortality for ECG abnormalities is lower in women than in men...
The evolution of public health sciences in an academic medical centerGregory L Burke
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1063, USA
South Med J 95:1248-53. 2002
Attempted control of hyperglycemia during cardiopulmonary bypass fails to improve neurologic or neurobehavioral outcomes in patients without diabetes mellitus undergoing coronary artery bypass graftingJohn Butterworth
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
J Thorac Cardiovasc Surg 130:1319. 2005....
COX-2 inhibitors--lessons in drug safetyBruce M Psaty
N Engl J Med 352:1133-5. 2005
Lipoprotein management in patients with cardiometabolic risk: consensus statement from the American Diabetes Association and the American College of Cardiology FoundationJohn D Brunzell
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and the Northwest Lipid Laboratory, University of Washington, Seattle, Washington, USA
Diabetes Care 31:811-22. 2008
Parecoxib, valdecoxib, and cardiovascular riskCurt D Furberg
Circulation 111:249. 2005
Rosiglitazone and cardiovascular riskBruce M Psaty
N Engl J Med 356:2522-4. 2007
Recent trials in hypertension: compelling science or commercial speech?Bruce M Psaty
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, USA
JAMA 295:1704-6. 2006
Characteristics and baseline clinical predictors of future fatal versus nonfatal coronary heart disease events in older adults: the Cardiovascular Health StudyCamille A Pearte
Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
Circulation 113:2177-85. 2006..Although >80% of annual coronary heart disease (CHD) deaths occur in adults aged >65 years and the population is aging rapidly, CHD event fatality and its predictors in the elderly have not been well described...
Long-term and short-term changes in antihypertensive prescribing by office-based physicians in the United StatesRandall S Stafford
Program on Prevention Outcomes and Practices, Stanford Prevention Research Center, Stanford University, Palo Alto, California, USA
Hypertension 48:213-8. 2006..The recorded long- and short-term trends indicate that evidence-based clinical recommendations had an impact on antihypertensive prescribing practices, but the magnitude of impact may be smaller and of more limited duration than desired...
Cost-effectiveness of chlorthalidone, amlodipine, and lisinopril as first-step treatment for patients with hypertension: an analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Paul A Heidenreich
VA Palo Alto Health Care System, Palo Alto, CA, USA
J Gen Intern Med 23:509-16. 2008..To evaluate the cost-effectiveness of first-line treatments for hypertension...
Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertensionGina D Schellenbaum
Department of Epidemiology, University of Washington, Seattle, Washington, USA
J Am Geriatr Soc 53:1996-2000. 2005..To determine whether angiotensin-converting enzyme (ACE) inhibitor use may be associated with weight maintenance and sustained muscle strength (measured by grip strength) in older adults...
Coronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factorsFrank M Sacks
Nutrition Department, Harvard School of Public Health F M S, Boston, Mass 02115, USA
Circulation 105:1424-8. 2002..We conducted exploratory analyses of participant characteristics, lipid risk factors, and risk reduction in this group...
The record on rosiglitazone and the risk of myocardial infarctionBruce M Psaty
N Engl J Med 357:67-9. 2007
Benefits of niacin by glycemic status in patients with healed myocardial infarction (from the Coronary Drug Project)Paul L Canner
Maryland Medical Research Institute, 600 Wyndhurst Avenue, Baltimore, MD 21210, USA
Am J Cardiol 95:254-7. 2005..Cardiovascular and total mortality outcomes in the niacin and placebo groups are presented by baseline glycemic status and by change in glycemic status from baseline to year 1...
Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysisBruce M Psaty
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, USA
JAMA 292:2622-31. 2004..As a result, the challenge of early detection has largely shifted to the US postmarketing systems...
Incidence, manifestations, and predictors of brain infarcts defined by serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health StudyW T Longstreth
Department of Neurology, University of Washington, Seattle, USA
Stroke 33:2376-82. 2002..MRI-defined infarcts are common in the elderly. We sought to explore incidence, manifestations, and predictors of such infarcts...
Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health StudyBruce M Psaty
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
Arch Intern Med 162:2325-32. 2002..More widespread use of these agents will be an important intervention to prevent the devastating complications of hypertension, including stroke, myocardial infarction, and heart failure...
Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiencyMichael G Shlipak
Department of Medicine, University of California, San Francisco, and the Veterans Affairs Medical Center, San Francisco 94121, USA
Circulation 107:87-92. 2003..Little is known about the association of renal insufficiency with inflammatory and procoagulant markers, which are potential mediators for the cardiovascular risk of kidney disease...
Risk factors and secondary prevention in women with heart disease: the Heart and Estrogen/progestin Replacement StudyEric Vittinghoff
University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, 74 New Montgomery, Suite 600, San Francisco, California 94105, USA
Ann Intern Med 138:81-9. 2003..Established drugs for secondary prevention, including aspirin, beta-blockers, and lipid-lowering agents, are underused in these women, especially those at highest risk...
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysisBruce M Psaty
Department of Medicine, University of Washington, Seattle, USA
JAMA 289:2534-44. 2003..Establishing relative benefit or harm from specific antihypertensive agents is limited by the complex array of studies that compare treatments. Network meta-analysis combines direct and indirect evidence to better define risk or benefit...
Differences in medical care and disease outcomes among black and white women with heart diseaseAshish K Jha
Division of General Medicine, San Francisco VA Medical Center, San Francisco, USA
Circulation 108:1089-94. 2003..We sought to evaluate differences in medical care and clinical outcomes among black and white women with established coronary artery disease...
Impact of clinical trial results on national trends in alpha-blocker prescribing, 1996-2002Randall S Stafford
Stanford Prevention Research Center, Stanford University, Stanford, Calif 94305, USA
JAMA 291:54-62. 2004..Research on factors that influence prescribing patterns and the extent of change produced by clinical trial findings is limited...
Creatinine levels and cardiovascular events in women with heart disease: do small changes matter?Michael G Shlipak
General Internal Medicine Section, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
Am J Kidney Dis 43:37-44. 2004....
Predictors of subsequent coronary events, stroke, and death among survivors of first hospitalized myocardial infarctionRobert C Kaplan
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Belfer Building, Room 1308C, Bronx, NY 10461, USA
J Clin Epidemiol 55:654-64. 2002..Finally, high creatinine was a strong, independent predictor of a variety of adverse outcomes after first MI...
Beyond hypertension toward guidelines for cardiovascular risk reductionMassimo Volpe
Department of Cardiology, II Faculty of Medicine, University of Rome La Sapienza Rome, Rome, Italy
Am J Hypertens 17:1068-74. 2004..We propose that global risk should be used as the main determinant of whom to treat, how to treat, and how much to treat...
Risk of congestive heart failure in an elderly population treated with peripheral alpha-1 antagonistsChris L Bryson
VA Puget Sound Health Services Research and Development, VAMC, Seattle, Washington 98108, USA
J Am Geriatr Soc 52:1648-54. 2004....
Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology FoundationJohn D Brunzell
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Northwest Lipid Laboratory, University of Washington, Seattle, Washington, USA
J Am Coll Cardiol 51:1512-24. 2008
Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment tBarry R Davis
The University of Texas School of Public Health, 1200 Herman Pressler Street, Houston, TX 77030, USA
Ann Intern Med 137:313-20. 2002..Sixty-eight percent (6167 of 9061) of the former patients and 59% (9081 of 15 256) of the latter patients were given additional medications to achieve a target blood pressure of less than 140/90 mm Hg...
Meta-analysis of health outcomes of chlorthalidone-based vs nonchlorthalidone-based low-dose diuretic therapiesBruce M Psaty
JAMA 292:43-4. 2004
ALLHAT: setting the record straightBarry R Davis
The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas 77030, USA
Ann Intern Med 141:39-46. 2004....
Medications and cardiovascular health in older adults: room for improvement in prevention and treatmentCaroline S Rhoads
Department of Medicine, University of Washington, Seattle, WA 98101, USA
Am J Geriatr Cardiol 13:161-7. 2004
Age as a modifiable risk factor for cardiovascular diseaseAllan D Sniderman
Mike Rosenbloom Laboratory for Cardiovascular Research, Royal Victoria Hospital, Montreal, Quebec, Canada
Lancet 371:1547-9. 2008
Serious adverse drug events reported to the Food and Drug Administration, 1998-2005Thomas J Moore
Institute for Safe Medication Practices, 1800 Byberry Rd, Ste 810, Huntingdon Valley, PA 19006, USA
Arch Intern Med 167:1752-9. 2007..The US Food and Drug Administration has operated the Adverse Event Reporting System since 1998. It collects all voluntary reports of adverse drug events submitted directly to the agency or through drug manufacturers...
Lipoprotein-associated phospholipase A2 and risk of venous thrombosis in older adultsNels Olson
Department of Pathology, University of Vermont College of Medicine, Burlington, Vermont, USA
Am J Hematol 83:524-7. 2008..Results were robust to several definitions of low or high Lp-PLA2. While the association of Lp-PLA(2) levels with arterial disease events implies a role for this enzyme in atherogenesis, our findings suggest that it is not prothrombotic...
Calcium channel blocker use and gastrointestinal tract bleeding among older adultsRobert C Kaplan
Age Ageing 31:217-8. 2002
Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function. The Cardiovascular Health StudyJohn S Gottdiener
St Francis Hospital, Roslyn, New York Mayo Clinic, Rochester, Minnesota 55905, USA
Ann Intern Med 137:631-9. 2002..Most persons with congestive heart failure are elderly, and many elderly persons with congestive heart failure have normal left ventricular systolic function...
Cardiovascular disease risk status in elderly persons with renal insufficiencyMichael G Shlipak
General Internal Medicine Section, Medical Service, Veterans Affairs Medical Center 111A1, 4150 Clement Street, San Francisco, CA 94121, USA
Kidney Int 62:997-1004. 2002..We determined the prevalence of elevated cardiovascular disease risk status among elderly persons with renal insufficiency...
Post hoc analysis of coronary findings from the prospective randomized evaluation of the vascular effects of the Norvasc trial (PREVENT)G B John Mancini
Vancouver Hospital, Vancouver, BC, Canada
Am J Cardiol 89:1414-6. 2002
From knowledge to practice in chronic cardiovascular disease: a long and winding roadSumit R Majumdar
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
J Am Coll Cardiol 43:1738-42. 2004..outline which of the strategies for translating evidence into clinical care have been shown to be ineffective, which strategies have been shown to be effective and to describe some untested approaches that hold promise...
The PROGRESS trial: questions about the effectiveness of angiotensin converting enzyme inhibitors. Perindopril pROtection aGainst REcurrent Stroke StudyBruce M Psaty
Am J Hypertens 15:472-4. 2002
The association between lipid levels and the risks of incident myocardial infarction, stroke, and total mortality: The Cardiovascular Health StudyBruce M Psaty
Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA
J Am Geriatr Soc 52:1639-47. 2004..To assess the association between lipid levels and cardiovascular events in older adults...
Contemplating ACTION--long-acting nifedipine in stable anginaBruce M Psaty
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA
Lancet 364:817-8. 2004
Benefits of niacin in patients with versus without the metabolic syndrome and healed myocardial infarction (from the Coronary Drug Project)Paul L Canner
Maryland Medical Research Institute, Baltimore, Maryland, USA
Am J Cardiol 97:477-9. 2006..86) in those without the MS (Z for interaction = 0.06, indicating homogeneity of the treatment effect across groups). In conclusion, these results support the use of niacin in postinfarction patients with and without the MS...
Evaluating professional performance in cardiovascular medicineRobert D Furberg
Evid Based Cardiovasc Med 10:75-8. 2006
Adverse cardiovascular effects of rofecoxibCurt D Furberg
N Engl J Med 355:204; author reply 204-5. 2006
The COX-2 inhibitors--an updateCurt D Furberg
Am Heart J 152:197-9. 2006
Recruitment of the elderly into a pharmacologic prevention trial: the Ginkgo Evaluation of Memory Study experienceAnnette L Fitzpatrick
Department of Epidemiology, University of Washington, Seattle, WA 98115, USA
Contemp Clin Trials 27:541-53. 2006..Information on the experience of the GEM Study recruitment may be helpful to other clinical trials attempting to randomize older adults into prevention trials...
Hypertension guidelines: criteria that might make them more clinically usefulMichael H Alderman
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
Am J Hypertens 15:917-23. 2002..Similarly, the benefit of therapy must be assessed by reduction in cardiovascular disease morbidity and mortality...
