Jasmin Divers

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Comparing self-reported ethnicity to genetic background measures in the context of the Multi-Ethnic Study of Atherosclerosis (MESA)
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest University School of Medicine Winston Salem, North Carolina 27157, USA
    BMC Genet 12:28. 2011
  2. ncbi The genetic architecture of lipoprotein subclasses in Gullah-speaking African American families enriched for type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Lipid Res 51:586-97. 2010
  3. ncbi Correcting for measurement error in individual ancestry estimates in structured association tests
    Jasmin Divers
    Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Services, Wake Forest University Health Sciences, Winston Salem, North Carolina 27101, USA
    Genetics 176:1823-33. 2007
  4. ncbi Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans
    Jessica N Cooke
    Program in Molecular Medicine and Translational Science, Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 27:1505-11. 2012
  5. ncbi Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 82:805-11. 2012
  6. ncbi Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD
    Barry I Freedman
    1Internal Medicine Nephrology, 2Biochemistry, 3Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 24:3366-71. 2009
  7. ncbi Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:260-7. 2009
  8. ncbi Genome-wide association of BMI in African Americans
    Maggie C Y Ng
    Center for Genomics and Personalized Medicine Research, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 20:622-7. 2012
  9. ncbi A genome-wide association search for type 2 diabetes genes in African Americans
    Nicholette D Palmer
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina, United States of America
    PLoS ONE 7:e29202. 2012
  10. ncbi Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans
    Barry I Freedman
    Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    PLoS Genet 7:e1002150. 2011

Detail Information

Publications38

  1. ncbi Comparing self-reported ethnicity to genetic background measures in the context of the Multi-Ethnic Study of Atherosclerosis (MESA)
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest University School of Medicine Winston Salem, North Carolina 27157, USA
    BMC Genet 12:28. 2011
    ..We compare the agreement between SRE and genetic based measures of ancestry (GBMA), and conduct simulation studies based on observed MESA data to evaluate the performance of each measure under various conditions...
  2. ncbi The genetic architecture of lipoprotein subclasses in Gullah-speaking African American families enriched for type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Jasmin Divers
    Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Lipid Res 51:586-97. 2010
    ....
  3. ncbi Correcting for measurement error in individual ancestry estimates in structured association tests
    Jasmin Divers
    Center for Public Health Genomics, Department of Biostatistical Sciences, Division of Public Health Services, Wake Forest University Health Sciences, Winston Salem, North Carolina 27101, USA
    Genetics 176:1823-33. 2007
    ..Our results show that the quadratic measurement error correction (QMEC) method performs better than the other methods and maintains the type I error to its nominal level...
  4. ncbi Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans
    Jessica N Cooke
    Program in Molecular Medicine and Translational Science, Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 27:1505-11. 2012
    ..We tested for association of single nucleotide polymorphisms (SNPs) in MYH9 with T2DM-ESRD in European Americans; additionally, three APOL1 gene variants were evaluated...
  5. ncbi Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 82:805-11. 2012
    ..After adjustment, two APOL1 risk variants weakly predict mild forms of kidney disease. Second hits appear necessary for the initiation of APOL1-associated nephropathy...
  6. ncbi Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD
    Barry I Freedman
    1Internal Medicine Nephrology, 2Biochemistry, 3Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 24:3366-71. 2009
    ....
  7. ncbi Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:260-7. 2009
    ..Affected relative pairs with type 2 diabetes were recruited through the Sea Islands Genetic African American Registry (Project SuGAR)...
  8. ncbi Genome-wide association of BMI in African Americans
    Maggie C Y Ng
    Center for Genomics and Personalized Medicine Research, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 20:622-7. 2012
    ..Further replication and meta-analysis in African Americans and other populations will shed light on the role of these loci in different ethnic populations...
  9. ncbi A genome-wide association search for type 2 diabetes genes in African Americans
    Nicholette D Palmer
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina, United States of America
    PLoS ONE 7:e29202. 2012
    ..These results suggest that multiple loci underlie T2DM susceptibility in the African-American population and that these loci are distinct from those identified in other ethnic populations...
  10. ncbi Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans
    Barry I Freedman
    Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    PLoS Genet 7:e1002150. 2011
    ..These analyses reveal a role for FRMD3 in AA T2DN susceptibility and accounting for c22 nephropathy risk variants can assist in detecting DN susceptibility genes...
  11. ncbi Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study
    Barry I Freedman
    Section on Nephrology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1053, USA
    Am J Nephrol 29:626-32. 2009
    ....
  12. ncbi Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans
    Barry I Freedman
    Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Nephrol Dial Transplant 26:3805-10. 2011
    ..Plasma HDL particle subclass concentrations were compared in 73 African Americans based on APOL1 genotypes to detect differences potentially contributing to renal disease...
  13. ncbi Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping
    Caitrin W McDonough
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Hum Genet 126:805-17. 2009
    ..0017; OR (95% CI) = 0.65 (0.50-0.85)]. Collectively, these results suggest that multiple genes in this region may influence diabetic nephropathy susceptibility in AAs...
  14. ncbi Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes
    Thomas C Register
    Department of Pathology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, USA
    J Clin Endocrinol Metab 98:E60-5. 2013
    ..Plasma DKK1, BMD in the spine, and CP in three arterial beds were assessed in African-Americans (AAs) to determine relationships of serum DKK1 with atherosclerotic vascular calcification...
  15. ncbi Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes
    Jasmin Divers
    Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1053, USA
    J Bone Miner Res 26:1554-60. 2011
    ..This relationship was independent of conventional CVD risk factors and supports the hypothesis that bone metabolism and atherosclerotic plaque mineralization are related processes...
  16. ncbi The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans
    Barry I Freedman
    Section on Nephrology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1053, USA
    Am J Nephrol 32:66-72. 2010
    ..Since MYH9 underlies approximately 40% of end-stage renal disease (ESRD) in AA, we tested for genetic association with LN...
  17. ncbi Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 18:2004-9. 2010
    ..004). As in European Americans, PAT is associated with CP in African Americans with type 2 diabetes. Ethnic differences in the relationships between organ-specific adipose tissue depots and atherosclerosis require further study...
  18. ncbi Ethnic differences in the relationship between pericardial adipose tissue and coronary artery calcified plaque: African-American-diabetes heart study
    Jasmin Divers
    Department of Public Health Sciences, Center for Diabetes Research, Section on Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1053, USA
    J Clin Endocrinol Metab 95:5382-9. 2010
    ..Because pericardial adipose tissue (PAT) is associated with CP in the neighboring coronary arteries, we explored ethnic-specific relationships between PAT and CP...
  19. ncbi Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease
    Keith L Keene
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Hum Genet 124:147-54. 2008
    ..This study presents exploratory analyses of the impact of admixture on studies of AA with T2DM-ESRD and supports the use of ancestral proportions as a means of reducing confounding effects due to admixture...
  20. ncbi Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans
    Joshua P Lewis
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Genomics 96:211-9. 2010
    ..0018-0.041). Mediation testing revealed that 30-40% of the effects of these SNPs on T2D were significantly mediated by BMI. SNPs near PREX1 may contribute to T2D susceptibility mediated through effects of adiposity in European Americans...
  21. ncbi Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes Care 33:131-8. 2010
    ..We explored ethnicity-specific relationships between albuminuria and calcified plaque involving the infrarenal aorta, coronary artery, and carotid artery in 835 European American and 393 African American subjects with type 2 diabetes...
  22. ncbi Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans
    Barry I Freedman
    Internal Medicine Nephrology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Kidney Int 75:736-45. 2009
    ..Our study shows that gene-environment and/or gene-gene interactions may initiate kidney disease in genetically susceptible individuals, because African Americans homozygous for MYH9 risk alleles do not universally develop kidney disease...
  23. ncbi Coincident idiopathic focal segmental glomerulosclerosis collapsing variant and diabetic nephropathy in an African American homozygous for MYH9 risk variants
    Isai Gopalakrishnan
    Department of Internal Medicine Nephrology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1053, USA
    Hum Pathol 42:291-4. 2011
    ....
  24. ncbi Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the african american-diabetes heart study
    Thomas C Register
    PhD, Department of Pathology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157
    J Clin Endocrinol Metab 98:1916-22. 2013
    ..The data support a regulatory/signaling role for adiponectin in the modulation of bone density...
  25. ncbi Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
    Jasmin Divers
    Departments of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC 27157 1053, USA
    Circ Cardiovasc Genet 6:97-105. 2013
    ....
  26. ncbi Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
    Mariana Murea
    Department of Internal Medicine Nephrology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC, 27157 1053, USA
    BMC Nephrol 13:148. 2012
    ..Relationships between serum MCP-1 concentration and early nephropathy and subclinical cardiovascular disease (CVD) were assessed in African Americans (AAs) with type 2 diabetes (T2D)...
  27. ncbi Susceptibility genes in common complex kidney disease
    Jasmin Divers
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1053, USA
    Curr Opin Nephrol Hypertens 19:79-84. 2010
    ..A brief overview of methods for identifying gene variants is provided, along with genetic associations and new avenues under exploration...
  28. ncbi Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes
    Mariana Murea
    Department of Internal Medicine, Section on Nephrology, Wake Forest University Baptist Medical Center, Winston Salem, NC 27157 1053, USA
    Am J Nephrol 33:502-9. 2011
    ..African-Americans (AAs) with diabetes have high incidence rates of end-stage renal disease (ESRD) with associated high mortality. Genetic factors modulating the risk of mortality on dialysis are poorly understood...
  29. ncbi Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans
    Pamela J Hicks
    Department of Biochemistry, Wake Forest School of Medicine, Winston Salem, North Carolina, USA 27157 1053
    Kidney Int 80:1339-43. 2011
    ..05) in dominant models. In addition, no evidence of APOL1 or MYH9 interactions with sickle cell trait was detected. Hence, sickle cell trait is not associated with diabetic or non-diabetic ESRD in a large sample of African Americans...
  30. ncbi Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes
    Lynne E Wagenknecht
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Ann Epidemiol 21:34-41. 2011
    ..To examine whether the relationship between cardiovascular disease risk factors and coronary artery calcification (CAC) is modified by race among those with diabetes...
  31. ncbi Vitamin d, adiposity, and calcified atherosclerotic plaque in african-americans
    Barry I Freedman
    Section on Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1053, USA
    J Clin Endocrinol Metab 95:1076-83. 2010
    ..Prospective trials are needed to determine the cardiovascular effects of supplemental vitamin D in this ethnic group...
  32. ncbi A genome-wide association study for diabetic nephropathy genes in African Americans
    Caitrin W McDonough
    Program in Molecular Medicine and Translational Science, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Kidney Int 79:563-72. 2011
    ..Thus, our results suggest that multiple loci underlie susceptibility to kidney disease in African Americans with type 2 diabetes and some may also contribute to all-cause ESRD...
  33. ncbi Genetic admixture: a tool to identify diabetic nephropathy genes in African Americans
    Jasmin Divers
    Division of Public Health Sciences, Department of Biostatistical Sciences, Section on Statistical Genetics and Bioinformatics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Ethn Dis 18:384-8. 2008
    ....
  34. ncbi Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    John B Harley
    Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, Oklahoma 73104, USA
    Nat Genet 40:204-10. 2008
    ..Our results show that numerous genes, some with known immune-related functions, predispose to SLE...
  35. ncbi Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies
    Joshua P Lewis
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes 57:2220-5. 2008
    ..Our objective was to examine the influence of type 2 diabetes genes identified in whole-genome association studies in a large African American case-control population...
  36. ncbi Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Sidharth A Shah
    Section on Cardiology, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Noninvasive Electrocardiol 18:29-40. 2013
    ..We used the Multi-Ethnic Study of Atherosclerosis to examine association of QT with NOS1AP variants in an ethnically diverse cohort...
  37. ncbi MYH9 is associated with nondiabetic end-stage renal disease in African Americans
    W H Linda Kao
    Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Nat Genet 40:1185-92. 2008
    ....
  38. ncbi Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model
    David T Redden
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS Genet 2:e137. 2006
    ....