SAMUEL DEADWYLER

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Effects of long-term exposure to delta9-THC on expression of cannabinoid receptor (CB1) mRNA in different rat brain regions
    S Zhuang
    Department of Physiology and Pharmacology, Centers for the Neurobiological, Investigation of Drug Abuse and Investigative Neuroscience, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Res Mol Brain Res 62:141-9. 1998
  2. pmc Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates
    Linda J Porrino
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
    PLoS Biol 3:e299. 2005
  3. ncbi request reprint Anatomic model of hippocampal encoding of spatial information
    S A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1800, USA
    Hippocampus 9:397-412. 1999
  4. ncbi request reprint Differential but complementary mnemonic functions of the hippocampus and subiculum
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Neuron 42:465-76. 2004
  5. ncbi request reprint Temporal coupling between subicular and hippocampal neurons underlies retention of trial-specific events
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1083, United States
    Behav Brain Res 174:272-80. 2006
  6. ncbi request reprint Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    J Neurosci 27:14239-47. 2007
  7. doi request reprint Endocannabinoids modulate encoding of sequential memory in the rat hippocampus
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157 1083, USA
    Psychopharmacology (Berl) 198:577-86. 2008
  8. ncbi request reprint Cannabinoid physiology and pharmacology: 30 years of progress
    Allyn C Howlett
    Neuroscience of Drug Abuse Research Program, Julius L Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC 27707, USA
    Neuropharmacology 47:345-58. 2004
  9. ncbi request reprint Restoring lost cognitive function
    Theodore W Berger
    USC Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA
    IEEE Eng Med Biol Mag 24:30-44. 2005

Research Grants

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Effects of long-term exposure to delta9-THC on expression of cannabinoid receptor (CB1) mRNA in different rat brain regions
    S Zhuang
    Department of Physiology and Pharmacology, Centers for the Neurobiological, Investigation of Drug Abuse and Investigative Neuroscience, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Brain Res Mol Brain Res 62:141-9. 1998
    ..Comparisons suggests that CB1 message may be regulated by different effector systems in each of the three areas during chronic Delta9-THC exposure...
  2. pmc Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates
    Linda J Porrino
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
    PLoS Biol 3:e299. 2005
    ....
  3. ncbi request reprint Anatomic model of hippocampal encoding of spatial information
    S A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1800, USA
    Hippocampus 9:397-412. 1999
    ..The model, therefore, appears to be more appropriate for memory required to return to particular locations than for initial guidance into those locations...
  4. ncbi request reprint Differential but complementary mnemonic functions of the hippocampus and subiculum
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Neuron 42:465-76. 2004
    ..The remaining 25% of trials were at risk due to inherent idiosyncrasies by which hippocampal and subicular neurons encoded information and became errors when the random sequence of trials conflicted with these constraints...
  5. ncbi request reprint Temporal coupling between subicular and hippocampal neurons underlies retention of trial-specific events
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1083, United States
    Behav Brain Res 174:272-80. 2006
    ....
  6. ncbi request reprint Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    J Neurosci 27:14239-47. 2007
    ..These findings provide strong evidence for the effectiveness of intranasal orexin-A in alleviating cognitive deficits produced by loss of sleep...
  7. doi request reprint Endocannabinoids modulate encoding of sequential memory in the rat hippocampus
    Sam A Deadwyler
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157 1083, USA
    Psychopharmacology (Berl) 198:577-86. 2008
    ....
  8. ncbi request reprint Cannabinoid physiology and pharmacology: 30 years of progress
    Allyn C Howlett
    Neuroscience of Drug Abuse Research Program, Julius L Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC 27707, USA
    Neuropharmacology 47:345-58. 2004
    ..One very important role for CB1 antagonists will be in the treatment of craving in the disease of substance abuse...
  9. ncbi request reprint Restoring lost cognitive function
    Theodore W Berger
    USC Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA
    IEEE Eng Med Biol Mag 24:30-44. 2005

Research Grants27

  1. LONG TERM BRAIN BEHAVIOR EFFECTS OF DELTA 9 THC
    SAMUEL DEADWYLER; Fiscal Year: 2004
    ..abstract_text> ..
  2. ELCTROPHYSIOLOGICAL ASSESSMENT OF CANNABINOID RECEPTORS
    SAMUEL DEADWYLER; Fiscal Year: 2005
    ....
  3. HIPPOCAMPUS CORRELATES OF DRUG ABUSE IN RATS
    SAMUEL DEADWYLER; Fiscal Year: 2007
    ..It will also provide him with the opportunity to expand his research on the above topics to include more advanced techniques and to continue collaborations with other well-known researchers in the field on topics of mutual interest. ..
  4. Neuronal Analysis of Cocaine Effects on Cognition
    SAMUEL DEADWYLER; Fiscal Year: 2007
    ..Therefore understanding how cocaine modulates and gradually over time eliminates effective cognitive processing, as studied here, is of primary importance in the prevention of drug addiction. ..
  5. Electrophysiological Assessment of Cannabinois Receptors
    Samuel A Deadwyler; Fiscal Year: 2010
    ..The outcomes of these studies will define not only what type of neural processes are susceptible to disruption by cannabinoid use, but also when the encoding of information by those processes is susceptible to such influence. ..
  6. Neuroimaging Correlates of Cocaine Reinforcement for Cognitive Performance
    Samuel A Deadwyler; Fiscal Year: 2010
    ..Primarily the Program will focus on the effects of cocaine on cognition in nonhuman primates which serves as the final testbed for candidate drugs that can lead to therapeutic treatment of cocaine abusers. ..
  7. DIFFERENTIAL GENE EXPRESSION & TOLERANCE TO CANNABINOIDS
    SAMUEL DEADWYLER; Fiscal Year: 2002
    ....
  8. ELECTROPHYSIOLOGICAL ASSESSMENT OF CANNABINOID RECEPTORS
    SAMUEL DEADWYLER; Fiscal Year: 1999
    ....
  9. NEUROPHYSIOLOGICAL ANALYSIS OF SELF ADMIN OF COCAINE
    SAMUEL DEADWYLER; Fiscal Year: 2002
    ..The program will provide important information regarding positive and/or negative motivational factors involved in cocaine self-administration. ..
  10. Neuronal Analysis of Cocaine Effects on Cognition
    Samuel A Deadwyler; Fiscal Year: 2010
    ..Therefore understanding how cocaine modulates and gradually over time eliminates effective cognitive processing, as studied here, is of primary importance in the prevention of drug addiction. ..