Carol C Cunningham

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Chronic ethanol, oxygen tension and hepatocyte energy metabolism
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1016, USA
    Front Biosci 4:D551-6. 1999
  2. ncbi Ethanol consumption and liver mitochondria function
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, N C 27157 1016, USA
    Biol Signals Recept 10:271-82. 2001
  3. ncbi Ethanol and protein metabolism
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Alcohol Clin Exp Res 25:262S-268S. 2001
  4. ncbi Chronic ethanol consumption decreases mitochondrial and glycolytic production of ATP in liver
    Tracey A Young
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    Alcohol Alcohol 41:254-60. 2006
  5. ncbi Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol
    Tracey A Young
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    Arch Biochem Biophys 405:65-72. 2002
  6. ncbi The effects of moderate ethanol consumption on the liver of the monkey, Macaca fascicularis
    Priscilla Ivester
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1016, USA
    Alcohol Clin Exp Res 27:1831-7. 2003
  7. ncbi Altered hepatic mitochondrial ribosome structure following chronic ethanol consumption
    Vinood B Patel
    Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1016, USA
    Arch Biochem Biophys 398:41-50. 2002
  8. ncbi Chronic binge-like moderate ethanol drinking in rats results in widespread decreases in brain serotonin, dopamine, and norepinephrine turnover rates reversed by ethanol intake
    James E Smith
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157 1083, USA
    J Neurochem 105:2134-55. 2008
  9. ncbi Energy availability and alcohol-related liver pathology
    Carol C Cunningham
    Department ofBiochemistry at Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
    Alcohol Res Health 27:291-9. 2003

Research Grants

  1. Ethanol effects on liver in self-administering primates
    Carol Cunningham; Fiscal Year: 2004
  2. CHRONIC ALCOHOLISM AND LIVER ENERGY AND LIPID METABOLISM
    Carol Cunningham; Fiscal Year: 2004

Collaborators

Detail Information

Publications9

  1. ncbi Chronic ethanol, oxygen tension and hepatocyte energy metabolism
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1016, USA
    Front Biosci 4:D551-6. 1999
    ..An investigation of the association between viability and cellular malondialdehyde levels revealed no effects of chronic ethanol consumption on MDA levels in hepatocytes that demonstrated ethanol-related decreases in cell viability...
  2. ncbi Ethanol consumption and liver mitochondria function
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, N C 27157 1016, USA
    Biol Signals Recept 10:271-82. 2001
    ..Both these semiquinones readily donate electrons to molecular oxygen to form superoxide...
  3. ncbi Ethanol and protein metabolism
    C C Cunningham
    Department of Biochemistry, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Alcohol Clin Exp Res 25:262S-268S. 2001
    ..Masaki, M. Mori, and Kunio Torii...
  4. ncbi Chronic ethanol consumption decreases mitochondrial and glycolytic production of ATP in liver
    Tracey A Young
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    Alcohol Alcohol 41:254-60. 2006
    ....
  5. ncbi Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol
    Tracey A Young
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA
    Arch Biochem Biophys 405:65-72. 2002
    ....
  6. ncbi The effects of moderate ethanol consumption on the liver of the monkey, Macaca fascicularis
    Priscilla Ivester
    Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1016, USA
    Alcohol Clin Exp Res 27:1831-7. 2003
    ..This is still a concern because some human studies suggest that levels of ethanol considered to be cardioprotective cause liver injury when consumed over a lifetime...
  7. ncbi Altered hepatic mitochondrial ribosome structure following chronic ethanol consumption
    Vinood B Patel
    Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157-1016, USA
    Arch Biochem Biophys 398:41-50. 2002
    ..The loss in ribosome function leads to impaired mitochondrial polypeptide synthesis and is an example of a pathology giving rise to an alteration in the mitochondrial ribosome structure...
  8. ncbi Chronic binge-like moderate ethanol drinking in rats results in widespread decreases in brain serotonin, dopamine, and norepinephrine turnover rates reversed by ethanol intake
    James E Smith
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157 1083, USA
    J Neurochem 105:2134-55. 2008
    ....
  9. ncbi Energy availability and alcohol-related liver pathology
    Carol C Cunningham
    Department ofBiochemistry at Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
    Alcohol Res Health 27:291-9. 2003
    ..An inadequate supply of ATP impairs the cell's ability to perform critical functions, including the repair of alcohol-induced cell damage, and may therefore contribute to cell death and alcoholic liver disease...

Research Grants2

  1. Ethanol effects on liver in self-administering primates
    Carol Cunningham; Fiscal Year: 2004
    ..fascicularis will develop liver pathology past the fatty liver stage and 2) to evaluate the efficacy of using blood and urine samples to follow development of alcoholic liver disease in an animal model. ..
  2. CHRONIC ALCOHOLISM AND LIVER ENERGY AND LIPID METABOLISM
    Carol Cunningham; Fiscal Year: 2004
    ..Phosphorus NMR spectroscopy will be utilized heavily in these latter studies. ..