Peter E Clark

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse of prostate cancer after definitive local therapy
    Peter E Clark
    Department of Urology and Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Urology 67:1257-61. 2006
  2. ncbi Prognostic significance of clinicopathologic and deoxyribonucleic acid flow cytometric variables in non-metastatic renal cell carcinoma in the modern era
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Urol Oncol 23:328-32. 2005
  3. ncbi Radical cystectomy in the elderly: comparison of clincal outcomes between younger and older patients
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Cancer 104:36-43. 2005
  4. ncbi Contemporary management of the urethra in patients after radical cystectomy for bladder cancer
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27104, USA
    Urol Clin North Am 32:199-206. 2005
  5. ncbi A rare case of an extra-adrenal myelolipoma arising in the renal sinus: a case report and review of the literature
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    ScientificWorldJournal 5:109-17. 2005
  6. ncbi Radical cystectomy in the elderly: Comparison of survival between younger and older patients
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
    Cancer 103:546-52. 2005
  7. ncbi The management of urethral transitional cell carcinoma after radical cystectomy for invasive bladder cancer
    Peter E Clark
    Department of Urology, University of Southern California Norris Cancer Center, Los Angeles, California, USA
    J Urol 172:1342-7. 2004
  8. ncbi Endourologic management of upper tract transitional cell carcinoma
    Peter E Clark
    Cleveland Clinic Foundation, Department of Urology, Cleveland, Ohio, USA
    ScientificWorldJournal 4:62-75. 2004
  9. ncbi A simple model predicts freedom from biochemical recurrence after low-dose rate prostate brachytherapy alone
    Michael A Papagikos
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Clin Oncol 30:199-204. 2007
  10. ncbi Microscopic and gross extravesical extension in pathological staging of bladder cancer
    Marcus L Quek
    Department of Urology, Kenneth Norris, Jr Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, 90089, USA
    J Urol 171:640-5. 2004

Collaborators

Detail Information

Publications55

  1. ncbi Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse of prostate cancer after definitive local therapy
    Peter E Clark
    Department of Urology and Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Urology 67:1257-61. 2006
    ..To report a prospective trial of lycopene supplementation in biochemically relapsed prostate cancer...
  2. ncbi Prognostic significance of clinicopathologic and deoxyribonucleic acid flow cytometric variables in non-metastatic renal cell carcinoma in the modern era
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Urol Oncol 23:328-32. 2005
    ..We sought to determine which variables correlated with overall survival and recurrence-free survival in the modern era...
  3. ncbi Radical cystectomy in the elderly: comparison of clincal outcomes between younger and older patients
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Cancer 104:36-43. 2005
    ....
  4. ncbi Contemporary management of the urethra in patients after radical cystectomy for bladder cancer
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27104, USA
    Urol Clin North Am 32:199-206. 2005
    ....
  5. ncbi A rare case of an extra-adrenal myelolipoma arising in the renal sinus: a case report and review of the literature
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    ScientificWorldJournal 5:109-17. 2005
  6. ncbi Radical cystectomy in the elderly: Comparison of survival between younger and older patients
    Peter E Clark
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
    Cancer 103:546-52. 2005
    ..The authors reported their experience with radical cystectomy for transitional cell carcinoma (TCC) of the bladder. They compared pathologic features and survival rates between older and younger patients...
  7. ncbi The management of urethral transitional cell carcinoma after radical cystectomy for invasive bladder cancer
    Peter E Clark
    Department of Urology, University of Southern California Norris Cancer Center, Los Angeles, California, USA
    J Urol 172:1342-7. 2004
    ..However, reports of the clinical presentation, treatment and outcome in these patients are lacking. We report our experience with the diagnosis, management and outcome of urethral TCC after radical cystectomy for bladder cancer...
  8. ncbi Endourologic management of upper tract transitional cell carcinoma
    Peter E Clark
    Cleveland Clinic Foundation, Department of Urology, Cleveland, Ohio, USA
    ScientificWorldJournal 4:62-75. 2004
  9. ncbi A simple model predicts freedom from biochemical recurrence after low-dose rate prostate brachytherapy alone
    Michael A Papagikos
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Clin Oncol 30:199-204. 2007
    ..The objective of this study was to describe a simple model that predicts freedom from biochemical recurrence (FFBR) in men with prostate cancer after treatment with low-dose rate prostate brachytherapy (LDRPB) alone...
  10. ncbi Microscopic and gross extravesical extension in pathological staging of bladder cancer
    Marcus L Quek
    Department of Urology, Kenneth Norris, Jr Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, 90089, USA
    J Urol 171:640-5. 2004
    ..We evaluated clinical outcomes in patients with pathological microscopic (pT3a) and gross (pT3b) extravesical tumor extension with transitional cell carcinoma (TCC) of the bladder following radical cystectomy...
  11. ncbi Natural history of surgically treated bladder carcinoma with extravesical tumor extension
    Marcus L Quek
    Department of Urology, Kenneth Norris Jr Comprehensive Cancer Center, University of Southern California Keck School of Medicine, MS 74, 1441 Eastlake Avenue, Suite 7476, Los Angeles, CA, USA
    Cancer 98:955-61. 2003
    ..The authors evaluated the outcomes of patients with pT3a and pT3b disease after radical cystectomy...
  12. pmc Masculinity and the body: how African American and White men experience cancer screening exams involving the rectum
    Julie A Winterich
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1084, USA
    Am J Mens Health 3:300-9. 2009
    ..Recommendations are provided for educational programs and physicians to improve men's experiences with exams that involve the rectum...
  13. ncbi Vinorelbine, doxorubicin, and prednisone in androgen-independent prostate cancer
    Lester S Borden
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer 107:1093-100. 2006
    ..The authors conducted a Phase II trial with vinorelbine, doxorubicin, and daily prednisone (NAP) to investigate the antitumor activity and palliative response of this regimen in patients with AIPC...
  14. ncbi Bladder cancer
    Eric S Gwynn
    Department of Urology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Curr Opin Oncol 18:277-83. 2006
    ..This article will review the diagnosis and management of bladder cancer at each stage, from superficial to metastatic disease with an emphasis on recent developments over the last year...
  15. ncbi Percutaneous CT-guided radiofrequency ablation of renal neoplasms: factors influencing success
    Ronald J Zagoria
    Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    AJR Am J Roentgenol 183:201-7. 2004
    ..The objective of our study was to evaluate the success rate for radiofrequency ablation of renal tumors and to determine the risk of serious complications...
  16. ncbi Bladder cancer
    Lester S Borden
    Department of Urology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Curr Opin Oncol 15:227-33. 2003
    ....
  17. ncbi Recent advances in the treatment of bladder cancer
    Eric S Gwynn
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 5:1023-30. 2005
    ..The current methods of detection, as well as available therapeutic treatment options are reviewed...
  18. ncbi Percentage of positive biopsies associated with freedom from biochemical recurrence after low-dose-rate prostate brachytherapy alone for clinically localized prostate cancer
    Peter J Rossi
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1030, USA
    Urology 67:349-53. 2006
    ..The PPBs has been associated with FFBR in men treated with radical prostatectomy and external beam radiotherapy for prostate cancer...
  19. ncbi Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas
    Ronald J Zagoria
    Department of Radiology, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157 1008, USA
    AJR Am J Roentgenol 189:429-36. 2007
    ..A single institution's experience with CT-guided percutaneous radiofrequency ablation of biopsy-proven renal cell carcinomas (RCCs) was studied to determine the disease-free survival and complication rate...
  20. ncbi CT-guided biopsy for the diagnosis of renal tumors before treatment with percutaneous ablation
    Marta E Heilbrun
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC, USA
    AJR Am J Roentgenol 188:1500-5. 2007
    ..The purpose of this retrospective study was to evaluate the role and utility of pretreatment CT-guided biopsy in patients referred for percutaneous thermal ablation of renal tumors...
  21. ncbi DNA damage levels in prostate cancer cases and controls
    Kristin L Lockett
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Carcinogenesis 27:1187-93. 2006
    ..However, larger case-control and follow-up studies are warranted to further evaluate the potential application of the alkaline Comet assay in CaP risk assessment and prevention...
  22. ncbi Phase II trial of combination interferon-alpha and thalidomide as first-line therapy in metastatic renal cell carcinoma
    Peter E Clark
    Department of Urology, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Urology 63:1061-5. 2004
    ..To present the results of a Phase II trial of thalidomide and interferon-alpha in renal cell carcinoma...
  23. pmc Waiting time from initial urological consultation to nephrectomy for renal cell carcinoma--does it affect survival?
    Andrew A Stec
    Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 179:2152-7. 2008
    ..We report survival and recurrence outcomes in all patients undergoing radical or partial nephrectomy for renal cell carcinoma, as related to surgical waiting time...
  24. ncbi Does a delay in initiating definitive therapy affect biochemical recurrence rates in men with clinically localized prostate cancer?
    Joseph J Phillips
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Urol Oncol 25:196-200. 2007
    ..To assess whether a delay in initiating definitive therapy for clinically localized prostate cancer affects outcome...
  25. ncbi Utility of frozen section analysis of resection margins during partial nephrectomy
    Dennis J Kubinski
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Urology 64:31-4. 2004
    ..Partial nephrectomy has gained acceptance for surgical treatment of small renal cancers. Many surgeons send specimens for intraoperative frozen section histologic analysis to ensure negative margins...
  26. ncbi Microwave ablation of renal parenchymal tumors before nephrectomy: phase I study
    Peter E Clark
    Department of Urology and Comprehensive Cancer Center of Wake Forest University, Winston Salem, NC, USA
    AJR Am J Roentgenol 188:1212-4. 2007
    ..There were no skip areas within the ablated zone. Microwave ablation can safely and quickly generate large ablation lesions and renal neoplasms...
  27. doi Smaller prostate size predicts high grade prostate cancer at final pathology
    Mark R Newton
    Department of Urology, University of Iowa, Iowa City, Iowa, USA
    J Urol 184:930-7. 2010
    ..Prostate size may influence the likelihood of detecting high grade prostate cancer at final pathology. We evaluated the association between prostate size and high grade (Gleason score 7 or greater) cancer...
  28. ncbi Dosimetric quantifiers for low-dose-rate prostate brachytherapy: is V(100) superior to D(90)?
    Michael A Papagikos
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1030, USA
    Brachytherapy 4:252-8. 2005
    ....
  29. ncbi The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme function
    Kristin L Lockett
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, North Carolina, 27157, USA
    Cancer Res 64:6344-8. 2004
    ..This study is the first to provide evidence that the ADPRT V762A-genetic variant contributes to CaP susceptibility and altered ADPRT/PARP-1 enzyme function in response to oxidative damage...
  30. ncbi Complementary and alternative medicine for advanced prostate cancer
    J Daniell Rackley
    Department of Urology, Wake Forest University School of Medicine, Comprehensive Cancer Center, Winston Salem, NC 27157 1094, USA
    Urol Clin North Am 33:237-46, viii. 2006
    ..In this article we summarize the use of some of the more common CAM nutritional supplements and review the scientific data that are available to support their use...
  31. ncbi The androgen receptor CAG repeat and prostate cancer risk
    Peter E Clark
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Methods Mol Med 81:255-66. 2003
  32. ncbi Bladder cancer
    Lester S Borden
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Curr Opin Oncol 17:275-80. 2005
    ..A brief overview of all aspects of bladder cancer including the etiology, diagnosis, and treatment are discussed with a focus on recent advances...
  33. doi Infant communicating hydroceles--do they need immediate repair or might some clinically resolve?
    Michelle E Koski
    Department of Urology, Division of Pediatric Urology, Monroe Carell Jr Children s Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, TN 37232 0001, USA
    J Pediatr Surg 45:590-3. 2010
    ..We have followed a series of infant boys with such hydroceles and reviewed their early natural history...
  34. ncbi Angiomyolipoma with vena caval extension
    Shandra S Wilson
    Department of Urology, Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Urology 60:695-6. 2002
  35. ncbi Male breast cancer during treatment with leuprolide for prostate cancer
    Joseph Yacoub
    Department of Radiation Oncology, Wake Forest University, Winston Salem, NC 27157, USA
    Clin Adv Hematol Oncol 5:555-6; discussion 556-7. 2007
  36. pmc Men's knowledge and beliefs about prostate cancer: education, race, and screening status
    Julie A Winterich
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Ethn Dis 19:199-203. 2009
    ..This study compared education, race, and screening status to determine how each factor shapes men's knowledge of prostate cancer and screening...
  37. ncbi Radiofrequency ablation of renal tumors
    Brian R Matlaga
    Department of Urology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Curr Urol Rep 5:39-44. 2004
    ..Although there is much optimism with regard to this technology, further study is required to better define the oncologic efficacy and refine proper patient selection...
  38. ncbi Inflammatory myofibroblastic tumor associated with renal cell carcinoma
    Eric S Gwynn
    Department of Urology, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Urology 66:880. 2005
    ..Some investigators have suggested that biopsy-proven IMT can be managed conservatively, but the findings of this report have demonstrated the need for radical nephrectomy in this patient population to rule out associated malignancy...
  39. doi Renal peripheral neuroectodermal tumor presenting at age 78: case report
    Michelle E Koski
    Department of Urology, Vanderbilt University Medical Center, Nashville, TN, USA
    ScientificWorldJournal 8:830-4. 2008
    ..To our knowledge, this is the most advanced age of presentation of this neoplasm to date. We report on her presentation and management, and discuss the current clinical management of this tumor...
  40. ncbi Bladder cancer
    Lester S Borden
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Curr Opin Oncol 16:257-62. 2004
    ..This article reviews recent advances in the diagnosis and management of bladder cancer...
  41. ncbi Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms
    Li Jia
    Department of Urology, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Mol Cancer Res 1:385-92. 2003
    ..These findings provide a contextual framework for interpreting the contribution of non-steroidal activation of the AR to signaling in vivo, and have implications for prostate cancer cell growth...
  42. ncbi Urinary diversion after radical cystectomy
    Peter E Clark
    Department of Urology, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Curr Treat Options Oncol 3:389-402. 2002
    ..As a result, radical cystectomy and urinary diversion should be performed at centers with significant experience in all three types of diversions...
  43. doi Sigmoid-urachal-cutaneous fistula in an adult male
    Benjamin J Coons
    Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Urology 73:444.e5-7. 2009
    ..Definitive management consisted of resection of the urachus with a bladder cuff, along with removal of the affected bowel segments and bowel anastomosis...
  44. doi Effect of a large prostate gland on open and robotically assisted laparoscopic radical prostatectomy
    Robert C Chan
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2765, USA
    BJU Int 101:1140-4. 2008
    ..To evaluate the outcomes based on gland size between robotically assisted radical prostatectomy (RALP) and open RP (RRP), as larger prostates might increase the difficulty of RP...
  45. doi Bladder cancer
    Daniel A Barocas
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Curr Opin Oncol 20:307-14. 2008
    ..To review the diagnosis and management of bladder cancer with an emphasis on studies and developments over the past year...
  46. ncbi Bladder cancer
    Peter E Clark
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Curr Opin Oncol 19:241-7. 2007
    ..This article reviews the diagnosis and management of bladder cancer with an emphasis on studies and developments over the past year...
  47. ncbi A comparison of the incidence and location of positive surgical margins in robotic assisted laparoscopic radical prostatectomy and open retropubic radical prostatectomy
    Joseph A Smith
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 178:2385-9; discussion 2389-90. 2007
    ..We evaluated the incidence and location of positive surgical margins in 200 sequential robotic assisted laparoscopic radical prostatectomy and 200 sequential open radical retropubic prostatectomy cases...
  48. ncbi Recent advances in targeted therapy for renal cell carcinoma
    Peter E Clark
    Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Curr Opin Urol 17:331-6. 2007
    ..To provide an overview and summary of the recent developments in the use of targeted therapy in the management of advanced kidney cancer. The focus is on publications within the last year...
  49. ncbi Upper tract transitional cell carcinoma: finding a way forward
    Peter E Clark
    Cancer 110:1648-9. 2007
  50. ncbi Association of procedure volume with radical cystectomy outcomes in a nationwide database
    Christopher E Barbieri
    Department of Urologic Surgery and Center for Clinical Improvement, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 178:1418-21; discussion 1421-2. 2007
    ..We examined the hospital characteristics associated with outcomes after radical cystectomy in a cohort study using results from a single, high volume academic institution as well as a nationwide data set of academic institutions...
  51. doi Contemporary open radical cystectomy: analysis of perioperative outcomes
    William T Lowrance
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    J Urol 179:1313-8; discussion 1318. 2008
    ..We reviewed our contemporary radical cystectomy series to evaluate perioperative outcome measures which could be affected by surgical approach for the purpose of establishing contemporary benchmarks for future comparisons...
  52. ncbi Assessing retroperitoneal lymphadenectomy experience in United States urological residency programs
    William T Lowrance
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Urol 178:500-3; discussion 503. 2007
    ..Surgical experience is important for the mastery of operative procedures. We evaluated the current United States urological surgical resident training in performing retroperitoneal lymph node dissection...
  53. pmc The von Hippel-Lindau gene: turning discovery into therapy
    Peter E Clark
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2765, USA
    Cancer 113:1768-78. 2008
    ....
  54. doi Interactions of cytokine gene polymorphisms in prostate cancer risk
    Jovanny Zabaleta
    Department of Genetics, Louisiana State University Health Sciences Center, 533 Bolivar Street, CSRB 455, New Orleans, LA 70112, USA
    Carcinogenesis 29:573-8. 2008
    ..92, 95% CI = 1.13-7.55) and the genotype combination of TNF-238GG plus IL10-592AA (OR = 2.14, 95% CI = 1.05-4.38). Our results highlight the importance of cytokine SNPs and their interactions in CaP risk...
  55. ncbi Neovesical-urethral anastomotic stricture after orthotopic urinary diversion: presentation and management
    Sanjay G Patel
    Vanderbilt University Medical Center, Department of Urologic Surgery, Nashville, TN 37232 5770, USA
    BJU Int 101:219-22. 2008
    ..To assess the frequency, presentation, treatment, and outcomes of bladder neck contractures (BNCs) among patients who had an orthotopic urinary diversion after radical cystectomy...