Jeff W Chou

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes
    Jeff W Chou
    Biostatistics Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA
    BMC Genomics 10:272. 2009
  2. ncbi Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes
    Jeff W Chou
    Microarray Group, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    BMC Bioinformatics 8:427. 2007
  3. ncbi Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence
    Danielle Duma
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, MD F3 07, Research Triangle Park, NC 27709, USA
    Sci Signal 3:ra74. 2010
  4. ncbi Systematic variation normalization in microarray data to get gene expression comparison unbiased
    Jeff W Chou
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Bioinform Comput Biol 3:225-41. 2005

Collaborators

Detail Information

Publications4

  1. ncbi Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes
    Jeff W Chou
    Biostatistics Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA
    BMC Genomics 10:272. 2009
    ..However, there are no straightforward ways of using co-expressed genes anchored to a phenotype or constrained by the experimental design for discerning mechanisms of a biological response...
  2. ncbi Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes
    Jeff W Chou
    Microarray Group, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    BMC Bioinformatics 8:427. 2007
    ..The approach utilizes the underlying structure of gene expression data to extract patterns and identify co-expressed genes that are responsive to experimental conditions...
  3. ncbi Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence
    Danielle Duma
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, MD F3 07, Research Triangle Park, NC 27709, USA
    Sci Signal 3:ra74. 2010
    ..These gender-specific actions of glucocorticoids in liver were substantiated in vivo with a sepsis model of systemic inflammation...
  4. ncbi Systematic variation normalization in microarray data to get gene expression comparison unbiased
    Jeff W Chou
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Bioinform Comput Biol 3:225-41. 2005
    ..Biologically meaningful comparisons of gene expression patterns between control and test channels or among multiple arrays are therefore unbiased using normalized but not unnormalized datasets...