Gregory Burke

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. pmc The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis
    Gregory L Burke
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Arch Intern Med 168:928-35. 2008
  2. ncbi request reprint Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women: the Soy Estrogen Alternative Study
    Gregory L Burke
    Departments of Public Health Sciences, Pathology, and Obstetrics and Gynecology, Wake Forest University School of Medicine, and Lyndhurst Gynecology Associates, Winston Salem, NC 27157, USA
    Menopause 10:147-53. 2003
  3. ncbi request reprint Racial differences in endothelial function in postmenopausal women
    Laura R Loehr
    Department of Internal Medicine, Sections on Section on Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am Heart J 148:606-11. 2004
  4. ncbi request reprint Heart failure prevalence, incidence, and mortality in the elderly with diabetes
    Alain G Bertoni
    Department of Public Health Science, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes Care 27:699-703. 2004
  5. doi request reprint Pericardial adipose tissue and coronary artery calcification in the Multi-ethnic Study of Atherosclerosis (MESA)
    JILL MCCLAIN
    Sticht Center on Aging, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 21:1056-63. 2013
  6. ncbi request reprint Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study
    Joseph Yeboah
    Department of Internal Medicine Cardiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Circulation 115:2390-7. 2007
  7. ncbi request reprint Mesenteric artery disease in the elderly
    Kimberley J Hansen
    Division of Surgical Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1095, USA
    J Vasc Surg 40:45-52. 2004
  8. doi request reprint The association of pericardial fat with calcified coronary plaque
    Jingzhong Ding
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 16:1914-9. 2008
  9. ncbi request reprint Renovascular disease and the risk of adverse coronary events in the elderly: a prospective, population-based study
    Matthew S Edwards
    Section on Vascular Surgery, Division of Surgical Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1095, USA
    Arch Intern Med 165:207-13. 2005
  10. ncbi request reprint Relationship between brachial flow-mediated dilation and carotid intima-media thickness in an elderly cohort: the Cardiovascular Health Study
    Joseph Yeboah
    Department of Internal Medicine Cardiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, United States
    Atherosclerosis 197:840-5. 2008

Research Grants

  1. MESA Family Study
    Gregory Burke; Fiscal Year: 2004
  2. MESA Family Study
    Gregory Burke; Fiscal Year: 2007

Detail Information

Publications65

  1. pmc The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis
    Gregory L Burke
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Arch Intern Med 168:928-35. 2008
    ..To assess the importance of the obesity epidemic on cardiovascular disease (CVD) risk, we determined the prevalence of obesity and the relationship of obesity to CVD risk factors and subclinical vascular disease...
  2. ncbi request reprint Soy protein and isoflavone effects on vasomotor symptoms in peri- and postmenopausal women: the Soy Estrogen Alternative Study
    Gregory L Burke
    Departments of Public Health Sciences, Pathology, and Obstetrics and Gynecology, Wake Forest University School of Medicine, and Lyndhurst Gynecology Associates, Winston Salem, NC 27157, USA
    Menopause 10:147-53. 2003
    ..To investigate the efficacy of dietary soy proteins containing differing amounts of isoflavones on the number and severity of vasomotor symptoms (hot flashes and night sweats) in peri- and postmenopausal women...
  3. ncbi request reprint Racial differences in endothelial function in postmenopausal women
    Laura R Loehr
    Department of Internal Medicine, Sections on Section on Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am Heart J 148:606-11. 2004
    ..To further study differences in endothelial function between African American and Caucasian women, we analyzed measures of brachial artery flow-mediated dilation (FMD) in women enrolled in the Cardiovascular Health Study (CHS)...
  4. ncbi request reprint Heart failure prevalence, incidence, and mortality in the elderly with diabetes
    Alain G Bertoni
    Department of Public Health Science, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes Care 27:699-703. 2004
    ..The goal of this study was to determine heart failure prevalence and incidence rates, subsequent mortality, and risk factors for heart failure among older populations in Medicare with diabetes...
  5. doi request reprint Pericardial adipose tissue and coronary artery calcification in the Multi-ethnic Study of Atherosclerosis (MESA)
    JILL MCCLAIN
    Sticht Center on Aging, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 21:1056-63. 2013
    ..To examine the relationship of pericardial adipose tissue (PAT) with coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis...
  6. ncbi request reprint Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study
    Joseph Yeboah
    Department of Internal Medicine Cardiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Circulation 115:2390-7. 2007
    ..We assessed the hypothesis that FMD predicts incident cardiovascular events in a population-based cohort of older adults...
  7. ncbi request reprint Mesenteric artery disease in the elderly
    Kimberley J Hansen
    Division of Surgical Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1095, USA
    J Vasc Surg 40:45-52. 2004
    ..The purpose of this study was to estimate the population-based prevalence of mesenteric artery stenosis (MAS) and occlusion among independent elderly Americans...
  8. doi request reprint The association of pericardial fat with calcified coronary plaque
    Jingzhong Ding
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 16:1914-9. 2008
    ..Pericardial fat has a higher secretion of inflammatory cytokines than subcutaneous fat. Cytokines released from pericardial fat around coronary arteries may act locally on the adjacent cells...
  9. ncbi request reprint Renovascular disease and the risk of adverse coronary events in the elderly: a prospective, population-based study
    Matthew S Edwards
    Section on Vascular Surgery, Division of Surgical Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1095, USA
    Arch Intern Med 165:207-13. 2005
    ..This investigation prospectively examined associations between renovascular disease and adverse coronary events among a population-based sample of elderly Americans...
  10. ncbi request reprint Relationship between brachial flow-mediated dilation and carotid intima-media thickness in an elderly cohort: the Cardiovascular Health Study
    Joseph Yeboah
    Department of Internal Medicine Cardiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, United States
    Atherosclerosis 197:840-5. 2008
    ..The aim of this study was to determine the relationship between brachial flow-mediated dilation (FMD) and carotid intima-media thickness (IMT) in a large multi-ethnic elderly cohort...
  11. ncbi request reprint Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study
    Matthew S Edwards
    Department of Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am J Kidney Dis 46:214-24. 2005
    ..We hypothesized that retinal microvascular abnormalities, when present, would be associated with progressive renal dysfunction in elderly individuals...
  12. ncbi request reprint Association between brachial artery reactivity and cardiovascular disease status in an elderly cohort: the cardiovascular health study
    Joseph Yeboah
    Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, United States
    Atherosclerosis 197:768-76. 2008
    ..We assessed the association of FMD and the presence or absence of subclinical and clinical CVD in a population based cohort of older adults...
  13. pmc Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Alain G Bertoni
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
    Diabetes Care 33:804-10. 2010
    ..Many studies have documented associations between inflammation and type 2 diabetes incidence. We assessed potential variability in this association in the major U.S. racial/ethnic groups...
  14. ncbi request reprint Prevalence of renovascular disease in the elderly: a population-based study
    Kimberley J Hansen
    Division of Surgical Sciences, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1095, USA
    J Vasc Surg 36:443-51. 2002
    ....
  15. pmc Association between non-subcutaneous adiposity and calcified coronary plaque: a substudy of the Multi-Ethnic Study of Atherosclerosis
    Jingzhong Ding
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am J Clin Nutr 88:645-50. 2008
    ..Excessive non-subcutaneous fat deposition may impair the functions of surrounding tissues and organs through the release of inflammatory cytokines and free fatty acids...
  16. pmc The association between physical activity and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis
    Alain G Bertoni
    Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Am J Epidemiol 169:444-54. 2009
    ..These data suggest that walking pace is associated with less subclinical atherosclerosis; these associations may be mediated by cardiovascular disease risk factors...
  17. pmc Gender differences between the Minnesota code and Novacode electrocardiographic prognostication of coronary heart disease in the cardiovascular health study
    Zhu Ming Zhang
    Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Cardiol 107:817-820.e1. 2011
    ..In conclusion, ECG classification systems for myocardial infarction/ischemia abnormalities by MC or Nova are valuable and useful for men and women in clinical trials and epidemiologic studies...
  18. pmc Effect of Ginkgo biloba on blood pressure and incidence of hypertension in elderly men and women
    Tina E Brinkley
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Hypertens 23:528-33. 2010
    ..Accumulating evidence suggests that Ginkgo biloba is cardioprotective, in part, through its vasodilatory and antihypertensive properties. However, definitive data on its blood pressure (BP)-lowering effects in humans is lacking...
  19. ncbi request reprint Associations between renovascular disease and prevalent cardiovascular disease in the elderly: a population-based study
    Matthew S Edwards
    Division of Surgical Sciences Section on Vascular Surgery, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Vasc Endovascular Surg 38:25-35. 2004
    ..These results suggest important population-based associations between RVD and both clinical and subclinical manifestations of CVD, especially coronary artery disease...
  20. ncbi request reprint Relationships between renovascular disease, blood pressure, and renal function in the elderly: a population-based study
    Matthew S Edwards
    Division of Surgical Sciences Section on Vascular Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157 1095, USA
    Am J Kidney Dis 41:990-6. 2003
    ..The purpose of this study is to examine the associations between renovascular disease (RVD) and cross-sectional measures of blood pressure and renal function among participants in the Cardiovascular Health Study (CHS)...
  21. ncbi request reprint White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study
    Lewis H Kuller
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 130 N Bellefield Ave, Rm 550, Pittsburgh, PA 15213, United States
    Neurobiol Aging 28:1307-15. 2007
    ..Low WMG and VG on MRI is a powerful determinant of long-term survival among older individuals...
  22. ncbi request reprint Subclinical atherosclerotic cardiovascular disease and early age-related macular degeneration in a multiracial cohort: the Multiethnic Study of Atherosclerosis
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison 53726 2397, USA
    Arch Ophthalmol 125:534-43. 2007
    ..To investigate the relationship of subclinical atherosclerotic cardiovascular disease (CVD) and its risk factors with age-related macular degeneration (AMD) in the Multiethnic Study of Atherosclerosis...
  23. pmc Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001
    Richard A Kronmal
    Collaborative Heath Studies Coordinating Center and Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
    PLoS Med 3:e400. 2006
    ..It is uncertain, however, whether excess DM mortality continues beyond age 75 years, is related to type of hypoglycemic therapy, and whether women continue to be disproportionately affected by DM into older age...
  24. ncbi request reprint Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis
    Bruce M Psaty
    Cardiovascular Health Research Unit, Department of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA
    Am J Hypertens 19:1110-7. 2006
    ..High blood pressure (BP) is associated with the presence and severity of subclinical disease. Less is known about associations between normal levels of BP and various measures of subclinical disease...
  25. ncbi request reprint Use of herbal medicine and other dietary supplements in community-dwelling older people: Baseline data from the ginkgo evaluation of memory study
    Richard L Nahin
    National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Am Geriatr Soc 54:1725-35. 2006
    ..To analyze baseline data from the Ginkgo Evaluation of Memory (GEM) study, in which information was collected on the use of all dietary supplements...
  26. ncbi request reprint Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA)
    Richard A Kronmal
    Department of Biostatistics, University of Washington, 6200 NE 74th St, Seattle, WA 98115, USA
    Circulation 115:2722-30. 2007
    ....
  27. pmc Associations of acculturation and socioeconomic status with subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis
    Pamela L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Public Health 98:1963-70. 2008
    ....
  28. doi request reprint Antidepressant treatment and worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study
    David C Steffens
    Department of Psychiatry, Duke University Medical Center, Box 3903, Durham, NC 27710, USA
    Stroke 39:857-62. 2008
    ..We hypothesized that Cardiovascular Health Study participants taking SSRIs would less often have worsening white matter on serial MRI than participants not on antidepressants...
  29. pmc Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726 2397, USA
    Ophthalmology 115:1742-9. 2008
    ....
  30. pmc Associations between microalbuminuria and animal foods, plant foods, and dietary patterns in the Multiethnic Study of Atherosclerosis
    Jennifer A Nettleton
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Am J Clin Nutr 87:1825-36. 2008
    ..The balance between the intake of animal and the intake of plant foods may influence renal vascular integrity as reflected by urinary albumin excretion...
  31. pmc Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second St, Ste 300, Minneapolis, MN 55454 1015, USA
    Arch Intern Med 168:1333-9. 2008
    ..Our objective was to assess whether maximum carotid IMT or CAC (Agatston score) is the better predictor of incident CVD...
  32. ncbi request reprint Modifications to the Healthy Eating Index and its ability to predict obesity: the Multi-Ethnic Study of Atherosclerosis
    Sue K Gao
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Am J Clin Nutr 88:64-9. 2008
    ..The Healthy Eating Index (HEI) is a measure of diet quality developed based on the Dietary Guidelines for Americans (DGA)...
  33. pmc A priori-defined dietary patterns and markers of cardiovascular disease risk in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Jennifer A Nettleton
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Am J Clin Nutr 88:185-94. 2008
    ..The level of detail regarding the dietary intake necessary to characterize associations between diet and cardiovascular disease (CVD) risk is uncertain...
  34. ncbi request reprint Intakes of long-chain n-3 polyunsaturated fatty acids and fish in relation to measurements of subclinical atherosclerosis
    Ka He
    Department of Nutrition, School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Clin Nutr 88:1111-8. 2008
    ..Data on the relations of different types of fish meals and long-chain n-3 polyunsaturated fatty acids (PUFAs) to measures of atherosclerosis are sparse...
  35. ncbi request reprint High rates of obesity and cardiovascular disease risk factors in lower middle class community in Pakistan: the Metroville Health Study
    Barbara Dennis
    Department of Biostatistics, University of North Carolina, Chapel Hill, USA
    J Pak Med Assoc 56:267-72. 2006
    ..To describe the distribution of over weight and body mass index, waist circumference and waist/ hip ratio, correlate obesity measures to coronary heart disease risk factors in comparison to Pakistan National Survey (PNS)...
  36. pmc The relation of atherosclerotic cardiovascular disease to retinopathy in people with diabetes in the Cardiovascular Health Study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, WI 53705 2397, USA
    Br J Ophthalmol 86:84-90. 2002
    ..To describe the association of retinopathy with atherosclerosis and atherosclerotic risk factors in people with diabetes...
  37. ncbi request reprint Incidence of cardiovascular disease in older Americans: the cardiovascular health study
    Alice M Arnold
    Department of Biostatistics, University of Washington, Seattle, USA
    J Am Geriatr Soc 53:211-8. 2005
    ..To estimate incidence rates of major cardiovascular disease (CVD) in older Americans...
  38. pmc Fish consumption and stroke risk in elderly individuals: the cardiovascular health study
    Dariush Mozaffarian
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Harvard School of Public Health, Boston, MA, USA
    Arch Intern Med 165:200-6. 2005
    ..Additionally, such relationships have not been specifically evaluated in the elderly, in whom disease burden may be high and diet less influential...
  39. ncbi request reprint The association of fasting glucose levels with congestive heart failure in diabetic adults > or =65 years: the Cardiovascular Health Study
    Joshua I Barzilay
    Kaiser Permanente of Georgia and the Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA
    J Am Coll Cardiol 43:2236-41. 2004
    ..The purpose of this study was to determine if fasting glucose levels are an independent risk factor for congestive heart failure (CHF) in elderly individuals with diabetes mellitus (DM) with or without coronary heart disease (CHD)...
  40. ncbi request reprint Early age-related maculopathy in the cardiovascular health study
    Ronald Klein
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726, USA
    Ophthalmology 110:25-33. 2003
    ..To describe the prevalence of early age-related maculopathy (ARM) and its relation to atherosclerosis, lipids, hypertension, and inflammatory factors in a population studied for cardiovascular disease risk factors and outcomes...
  41. ncbi request reprint Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health Study
    Bruce M Psaty
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    Arch Intern Med 162:2325-32. 2002
    ..Control of high blood pressure (BP) in older adults is an important part of public health efforts at prevention...
  42. ncbi request reprint Multi-ethnic study of atherosclerosis: objectives and design
    Diane E Bild
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Am J Epidemiol 156:871-81. 2002
    ....
  43. ncbi request reprint Relationship between coronary artery calcification and other measures of subclinical cardiovascular disease in older adults
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
    Arterioscler Thromb Vasc Biol 22:1674-9. 2002
    ..In the Cardiovascular Health Study, subclinical cardiovascular disease (CVD) predicted CVD events in older adults. The extent to which this measure or its components reflect calcified coronary disease is unknown...
  44. ncbi request reprint Cerebrovascular disease and evolution of depressive symptoms in the cardiovascular health study
    David C Steffens
    Duke University Medical Center, Department of Psychiatry, Durham, NC 27710, USA
    Stroke 33:1636-44. 2002
    ..The Cardiovascular Health Study (CHS) provides an opportunity to examine the relationship between vascular brain pathology seen on neuroimaging and changes in depressive symptoms...
  45. ncbi request reprint C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study
    Mary Cushman
    Department of Medicine, University of Vermont, Burlington, VT, USA
    Circulation 112:25-31. 2005
    ..High C-reactive protein (CRP) is associated with increased coronary heart disease risk. Few long-term data in the elderly are available...
  46. ncbi request reprint Risk factors for declining ankle-brachial index in men and women 65 years or older: the Cardiovascular Health Study
    Margaret Kennedy
    Department of Medicine, University of Vermont, Burlington, USA
    Arch Intern Med 165:1896-902. 2005
    ..9 is a noninvasive measure of lower extremity arterial disease and a predictor of cardiovascular events. Little information is available on longitudinal change in ABI or on risk factors for declining ABI in a community-based population...
  47. ncbi request reprint 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study
    Lewis H Kuller
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Intern Med 166:71-8. 2006
    ..The incidence of coronary heart disease (CHD) is very high among individuals 65 years or older...
  48. ncbi request reprint Smoking, diabetes, and blood cholesterol differ in their associations with subclinical atherosclerosis: the Multiethnic Study of Atherosclerosis (MESA)
    A Richey Sharrett
    The Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, 615N Wolfe St, Room E6518, Baltimore, MD 21205, USA
    Atherosclerosis 186:441-7. 2006
    ..Diabetes contributes uniquely to arterial stiffness...
  49. ncbi request reprint Alcohol use and risk of ischemic stroke among older adults: the cardiovascular health study
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Stroke 36:1830-4. 2005
    ..The association of light to moderate alcohol consumption with risk of ischemic stroke remains uncertain, as are the roles of potentially mediating factors and modification by apolipoprotein E (apoE) genotype...
  50. pmc Thyroid status, cardiovascular risk, and mortality in older adults
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 295:1033-41. 2006
    ..Previous studies have suggested that subclinical abnormalities in thyroid-stimulating hormone levels are associated with detrimental effects on the cardiovascular system...
  51. ncbi request reprint Therapy with hydroxymethylglutaryl coenzyme a reductase inhibitors (statins) and associated risk of incident cardiovascular events in older adults: evidence from the Cardiovascular Health Study
    Rozenn N Lemaitre
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA
    Arch Intern Med 162:1395-400. 2002
    ....
  52. ncbi request reprint Alcohol consumption and risk of coronary heart disease in older adults: the Cardiovascular Health Study
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Am Geriatr Soc 54:30-7. 2006
    ..To evaluate several aspects of the relationship between alcohol use and coronary heart disease in older adults, including beverage type, mediating factors, and type of outcome...
  53. ncbi request reprint Associations between two common polymorphisms in the ABCA1 gene and subclinical atherosclerosis: Multi-Ethnic Study of Atherosclerosis (MESA)
    Jeana L Benton
    The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Atherosclerosis 193:352-60. 2007
    ..We examined these associations in a sample of Multi-Ethnic Study of Atherosclerosis (MESA) participants...
  54. ncbi request reprint The aging and dying processes and the health of older adults
    Paula Diehr
    Department of Biostatistics, University of Washington, Box 357232, Seattle, WA 98195, USA
    J Clin Epidemiol 55:269-78. 2002
    ..The "effect" of the dying process was usually significantly larger than the effect of aging. Large declines in these health measures are probably not due to aging, and should be taken seriously by patients and their providers...
  55. pmc Inflammatory markers and longitudinal lung function decline in the elderly
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Epidemiol 168:602-10. 2008
    ..An alternative approach to missing data yielded similar results. In conclusion, higher levels of fibrinogen, but not CRP, independently predicted greater FEV(1)/FVC decline in the elderly...
  56. ncbi request reprint Statin use and the risk of incident dementia: the Cardiovascular Health Study
    Thomas D Rea
    Department of Medicine, University of Washington, Seattle 98101, USA
    Arch Neurol 62:1047-51. 2005
    ..Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce cardiovascular risk through mechanisms that might affect the development of dementia...
  57. ncbi request reprint Cereal, fruit, and vegetable fiber intake and the risk of cardiovascular disease in elderly individuals
    Dariush Mozaffarian
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Wash, USA
    JAMA 289:1659-66. 2003
    ..Additionally, the influence of dietary habits on risk may be less pronounced in elderly persons, when atherosclerosis is more advanced. However, few data address the influence of diet on CVD risk in this population...
  58. ncbi request reprint 34th Bethesda Conference: Task force #4--How do we select patients for atherosclerosis imaging?
    Peter W F Wilson
    School of Medicine, Boston University, 715 Albany Street, Evans E204, Boston, MA 02118, USA
    J Am Coll Cardiol 41:1898-906. 2003
  59. ncbi request reprint "Successful aging": effect of subclinical cardiovascular disease
    Anne B Newman
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Intern Med 163:2315-22. 2003
    ..Among those without clinical disease, high levels of subclinical disease are associated with poor survival. The effect of the extent of subclinical cardiovascular disease on the quality of the remaining years has not been defined...
  60. ncbi request reprint Lifestyles of older adults: can we influence cardiovascular risk in older adults?
    Dariush Mozaffarian
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Geriatr Cardiol 13:153-60. 2004
    ..Clinical practice and public health implications, gaps in knowledge, and future research directions are summarized...
  61. ncbi request reprint The relationship of fasting serum radioimmune insulin levels to incident coronary heart disease in an insulin-treated diabetic cohort
    Richard A Kronmal
    Department of Biostatistics, University of Washington, Seattle, Washington 98115, USA
    J Clin Endocrinol Metab 89:2852-8. 2004
    ..These observational findings should be confirmed through larger prospective studies, given their implications for insulin therapy...
  62. pmc Fish intake and risk of incident atrial fibrillation
    Dariush Mozaffarian
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, and Department of Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Circulation 110:368-73. 2004
    ..Although effects of fish intake, including potential antiarrhythmic effects, may favorably influence risk of AF, relationships between fish intake and AF incidence have not been evaluated...
  63. ncbi request reprint Nonfinancial incentives for quality: a policy statement from the American Heart Association
    Vincent Bufalino
    Midwest Heart Specialists
    Circulation 115:398-401. 2007
  64. ncbi request reprint Fish intake and risk of incident heart failure
    Dariush Mozaffarian
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J Am Coll Cardiol 45:2015-21. 2005
    ..Our aim was to investigate the relation between fish consumption and incidence of congestive heart failure (CHF)...
  65. ncbi request reprint Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death
    Nona Sotoodehnia
    Department of Medicine, University of Washington, Seattle, WA, USA
    Circulation 113:1842-8. 2006
    ..Sympathetic activation influences the risk of ventricular arrhythmias and sudden cardiac death (SCD), mediated in part by the beta2-adrenergic receptor (B2AR). We investigated whether variation in the B2AR gene is associated with SCD risk...

Research Grants6

  1. MESA Family Study
    Gregory Burke; Fiscal Year: 2004
    ..abstract_text> ..
  2. MESA Family Study
    Gregory Burke; Fiscal Year: 2007
    ..abstract_text> ..