Walter T Ambrosius
Affiliation: Wake Forest University School of Medicine
- Intensive short courses in biostatistics for fellows and physiciansWalter T Ambrosius
Section on Biostatistics, Department of Public Health Sciences, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
Stat Med 21:2739-56. 2002..Finally, we will cover the financial arrangements that we have made when teaching these courses...
- Power for studies with random group sizesWalter T Ambrosius
Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
Stat Med 29:1137-44. 2010..We find that standard estimates of power using expected group sizes can over or underestimate power. SAS macros are available at http://www.phs.wfubmc.edu/public/wambrosi/RandomPower...
- Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudyWalter T Ambrosius
Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Arch Ophthalmol 128:312-8. 2010..To assess the cross-sectional association of thiazolidinediones with diabetic macular edema (DME)...
- Power for genetic association studies with random allele frequencies and genotype distributionsWalter T Ambrosius
Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Am J Hum Genet 74:683-93. 2004..We show that ignoring the sources of variation in allele frequencies tends to result in overestimates of power and, consequently, in studies that are underpowered. Software in C is available at http://www.ambrosius.net/Power/...
- Cross calibration in longitudinal studiesWalter T Ambrosius
Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
Stat Med 23:2845-61. 2004..Finally, simulation results are presented to show the superiority of the proposed method over existing methods of cross calibration...
- Quality of heart failure care in managed Medicare and Medicaid patients in North CarolinaAlain G Bertoni
Department of Public Health Sciences, Winston-Salem, North Carolina, USA
Am J Cardiol 93:714-8. 2004..Opportunities for improvement remain, particularly for beta-blocker use...
- Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainmentJohn R Crouse
Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Am J Cardiol 97:1667-9. 2006
- Controlling prescription drug expenditures: a report of successDavid P Miller
General Internal Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Am J Manag Care 13:473-80. 2007..To determine whether a multi-interventional program can limit increases in prescription drug expenditures while maintaining utilization of needed medications...
- Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition studyHal H Atkinson
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Gerontol A Biol Sci Med Sci 62:844-50. 2007..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults...
- Enhancing quality of heart failure care in managed Medicare and Medicaid in North Carolina: results of the North Carolina Achieving Cardiac Excellence (NC ACE) ProjectDavid C Goff
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Am Heart J 150:717-24. 2005..To evaluate an intervention to improve the quality of care of patients with heart failure in managed Medicare and Medicaid plans in North Carolina...
- Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged ratsChristy S Carter
Sticht Center on Aging, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Gerontol A Biol Sci Med Sci 59:416-23. 2004..These results suggest that ACE inhibition may prevent age-related declines in physical performance, which may be mediated by a reduction in body fat mass...
- Dietary oxalate loads and renal oxalate handlingRoss P Holmes
Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Urol 174:943-7; discussion 947. 2005..We examined changes in plasma and urinary oxalate following oral crystalline oxalate loading under controlled dietary conditions to further define the renal handling of oxalate by normal adults...
- Design of the value of imaging in enhancing the wellness of your heart (VIEW) trial and the impact of uncertainty on powerWalter T Ambrosius
Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
Clin Trials 9:232-46. 2012....
- Power and sample sizeL Douglas Case
Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
Methods Mol Biol 404:377-408. 2007..We will show how the power and required sample size can be calculated for several common types of studies, mention software that can be used for the necessary calculations, and discuss additional considerations...
- The effect of intensive risk factor management in type 2 diabetes on inflammatory biomarkersXanthia F Samaropoulos
Wake Forest School of Medicine, Division of Public Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, United States
Diabetes Res Clin Pract 95:389-98. 2012....
- Translating weight loss and physical activity programs into the community to preserve mobility in older, obese adults in poor cardiovascular healthW Jack Rejeski
Department of Health and Exercise Science and Geriatric Medicine, Wake Forest University, Winston Salem, NC 27109, USA
Arch Intern Med 171:880-6. 2011..Our goal was to determine the effects of a physical activity and weight loss intervention on 18-month change in mobility among overweight or obese older adults in poor cardiovascular health...
- Age, body mass index, and gender differences in sacroiliac joint pathologyRobert W Irwin
Department of Rehabilitation Medicine, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
Am J Phys Med Rehabil 86:37-44. 2007..To evaluate the correlation between age, gender, and body mass index as they relate to sacroiliac joint pathology diagnosed by dual comparative local anesthetic blocks...
- Racial difference in the activity of the amiloride-sensitive epithelial sodium channelJ Howard Pratt
Department of Medicine, Indiana University School of Medicine, Indianapolis, Ind, USA
Hypertension 40:903-8. 2002..We suggest that increased sodium retention in blacks occurring at other nephron sites suppresses aldosterone secretion and in turn ENaC function...
- The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activityJ Christopher Gorski
Department of Medicine, Indiana University School of Medicine, Wishard Memorial Hospital, Indianapolis, 46202 2879, USA
Clin Pharmacol Ther 74:275-87. 2003..The relative susceptibility of intestinal and hepatic cytochrome P450 (CYP) 3A to induction by rifampin (INN, rifampicin), as a function of age and sex, was investigated with the CYP3A substrate midazolam...
- Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors studyMatteo Cesari
Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
Am J Clin Nutr 82:428-34. 2005..Age-related body-composition changes are associated with health-related outcomes in elders. This relation may be explained by inflammation and hemostatic abnormalities...
- Group-mediated activity counseling and traditional exercise therapy programs: effects on health-related quality of life among older adults in cardiac rehabilitationBrian C Focht
Department of Exercise and Sport Science, East Carolina University, Greenville 27858, USA
Ann Behav Med 28:52-61. 2004..Nevertheless, systematic investigations of the influence of exercise therapy on older men and women enrolled in cardiac rehabilitation remain sparse...
- Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORD-EYE)Emily Y Chew
Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 1204, USA
Am J Cardiol 99:103i-111i. 2007..These data will provide valuable information regarding the effects of medical treatment on the prevention and progression of DR...
- Activity of 11beta-hydroxysteroid dehydrogenase type 2 in normotensive blacks and whitesR Ravi Shankar
Indiana University School of Medicine Indianapolis, Indiana, USA
Ethn Dis 15:407-10. 2005..35 for an overall effect of race. CONDUSION: 11betaHSD2 activity appears to be similar in Blacks and Whites and probably contributes minimally, if at all, to race differences in sodium retention...