Walter T Ambrosius

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Intensive short courses in biostatistics for fellows and physicians
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Stat Med 21:2739-56. 2002
  2. pmc Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy
    Walter T Ambrosius
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Ophthalmol 128:312-8. 2010
  3. pmc Power for studies with random group sizes
    Walter T Ambrosius
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
    Stat Med 29:1137-44. 2010
  4. ncbi request reprint Cross calibration in longitudinal studies
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
    Stat Med 23:2845-61. 2004
  5. pmc Power for genetic association studies with random allele frequencies and genotype distributions
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Hum Genet 74:683-93. 2004
  6. ncbi request reprint Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina
    Alain G Bertoni
    Department of Public Health Sciences, Winston Salem, North Carolina, USA
    Am J Cardiol 93:714-8. 2004
  7. pmc Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults
    Kristen M Beavers
    Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, J Paul Sticht Center on Aging, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Am Geriatr Soc 61:1089-94. 2013
  8. pmc Effect of an 18-month physical activity and weight loss intervention on body composition in overweight and obese older adults
    Kristen M Beavers
    Department of Health and Exercise Science, Wake Forest University, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 22:325-31. 2014
  9. ncbi request reprint Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study
    Hal H Atkinson
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 62:844-50. 2007
  10. ncbi request reprint Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainment
    John R Crouse
    Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Cardiol 97:1667-9. 2006

Detail Information

Publications27

  1. ncbi request reprint Intensive short courses in biostatistics for fellows and physicians
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Stat Med 21:2739-56. 2002
    ..Finally, we will cover the financial arrangements that we have made when teaching these courses...
  2. pmc Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy
    Walter T Ambrosius
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Ophthalmol 128:312-8. 2010
    ..To assess the cross-sectional association of thiazolidinediones with diabetic macular edema (DME)...
  3. pmc Power for studies with random group sizes
    Walter T Ambrosius
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
    Stat Med 29:1137-44. 2010
    ..We find that standard estimates of power using expected group sizes can over or underestimate power. SAS macros are available at http://www.phs.wfubmc.edu/public/wambrosi/RandomPower...
  4. ncbi request reprint Cross calibration in longitudinal studies
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
    Stat Med 23:2845-61. 2004
    ..Finally, simulation results are presented to show the superiority of the proposed method over existing methods of cross calibration...
  5. pmc Power for genetic association studies with random allele frequencies and genotype distributions
    Walter T Ambrosius
    Section on Biostatistics, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Hum Genet 74:683-93. 2004
    ..We show that ignoring the sources of variation in allele frequencies tends to result in overestimates of power and, consequently, in studies that are underpowered. Software in C is available at http://www.ambrosius.net/Power/...
  6. ncbi request reprint Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina
    Alain G Bertoni
    Department of Public Health Sciences, Winston Salem, North Carolina, USA
    Am J Cardiol 93:714-8. 2004
    ..Opportunities for improvement remain, particularly for beta-blocker use...
  7. pmc Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults
    Kristen M Beavers
    Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, J Paul Sticht Center on Aging, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Am Geriatr Soc 61:1089-94. 2013
    ..To determine the independent effect of long-term physical activity (PA) and the combined effects of long-term PA and weight loss (WL) on inflammation in overweight and obese older adults...
  8. pmc Effect of an 18-month physical activity and weight loss intervention on body composition in overweight and obese older adults
    Kristen M Beavers
    Department of Health and Exercise Science, Wake Forest University, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 22:325-31. 2014
    ..Secondarily, the association between change in body mass and composition on change in several cardiometabolic risk factors and mobility was evaluated...
  9. ncbi request reprint Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study
    Hal H Atkinson
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 62:844-50. 2007
    ..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults...
  10. ncbi request reprint Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainment
    John R Crouse
    Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Cardiol 97:1667-9. 2006
  11. ncbi request reprint Enhancing quality of heart failure care in managed Medicare and Medicaid in North Carolina: results of the North Carolina Achieving Cardiac Excellence (NC ACE) Project
    David C Goff
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
    Am Heart J 150:717-24. 2005
    ..To evaluate an intervention to improve the quality of care of patients with heart failure in managed Medicare and Medicaid plans in North Carolina...
  12. ncbi request reprint Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats
    Christy S Carter
    Sticht Center on Aging, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 59:416-23. 2004
    ..These results suggest that ACE inhibition may prevent age-related declines in physical performance, which may be mediated by a reduction in body fat mass...
  13. ncbi request reprint Dietary oxalate loads and renal oxalate handling
    Ross P Holmes
    Department of Urology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Urol 174:943-7; discussion 947. 2005
    ..We examined changes in plasma and urinary oxalate following oral crystalline oxalate loading under controlled dietary conditions to further define the renal handling of oxalate by normal adults...
  14. ncbi request reprint Controlling prescription drug expenditures: a report of success
    David P Miller
    General Internal Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Am J Manag Care 13:473-80. 2007
    ..To determine whether a multi-interventional program can limit increases in prescription drug expenditures while maintaining utilization of needed medications...
  15. doi request reprint Design of the value of imaging in enhancing the wellness of your heart (VIEW) trial and the impact of uncertainty on power
    Walter T Ambrosius
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1063, USA
    Clin Trials 9:232-46. 2012
    ....
  16. pmc Application of random forests methods to diabetic retinopathy classification analyses
    Ramon Casanova
    Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, North Carolina, United States of America
    PLoS ONE 9:e98587. 2014
    ..DR is a silent disease that may go unnoticed until it is too late for effective treatment. Therefore, early detection could improve the chances of therapeutic interventions that would alleviate its effects...
  17. ncbi request reprint Power and sample size
    L Douglas Case
    Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
    Methods Mol Biol 404:377-408. 2007
    ..We will show how the power and required sample size can be calculated for several common types of studies, mention software that can be used for the necessary calculations, and discuss additional considerations...
  18. pmc The Cooperative Lifestyle Intervention Program-II (CLIP-II): design and methods
    Anthony P Marsh
    Department of Health and Exercise Science, Wake Forest University, Winston Salem, NC 27109, USA Electronic address
    Contemp Clin Trials 36:382-93. 2013
    ..Because uncertainty exists about the best approach for promoting WL in older adults due to concerns with the loss of lean mass, the design also permits a contrast between AT+WL and RT+WL on muscle strength...
  19. doi request reprint The effect of intensive risk factor management in type 2 diabetes on inflammatory biomarkers
    Xanthia F Samaropoulos
    Wake Forest School of Medicine, Division of Public Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, United States
    Diabetes Res Clin Pract 95:389-98. 2012
    ....
  20. doi request reprint Translating weight loss and physical activity programs into the community to preserve mobility in older, obese adults in poor cardiovascular health
    W Jack Rejeski
    Department of Health and Exercise Science and Geriatric Medicine, Wake Forest University, Winston Salem, NC 27109, USA
    Arch Intern Med 171:880-6. 2011
    ..Our goal was to determine the effects of a physical activity and weight loss intervention on 18-month change in mobility among overweight or obese older adults in poor cardiovascular health...
  21. ncbi request reprint Racial difference in the activity of the amiloride-sensitive epithelial sodium channel
    J Howard Pratt
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Ind, USA
    Hypertension 40:903-8. 2002
    ..We suggest that increased sodium retention in blacks occurring at other nephron sites suppresses aldosterone secretion and in turn ENaC function...
  22. ncbi request reprint The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity
    J Christopher Gorski
    Department of Medicine, Indiana University School of Medicine, Wishard Memorial Hospital, Indianapolis, 46202 2879, USA
    Clin Pharmacol Ther 74:275-87. 2003
    ..The relative susceptibility of intestinal and hepatic cytochrome P450 (CYP) 3A to induction by rifampin (INN, rifampicin), as a function of age and sex, was investigated with the CYP3A substrate midazolam...
  23. ncbi request reprint Group-mediated activity counseling and traditional exercise therapy programs: effects on health-related quality of life among older adults in cardiac rehabilitation
    Brian C Focht
    Department of Exercise and Sport Science, East Carolina University, Greenville 27858, USA
    Ann Behav Med 28:52-61. 2004
    ..Nevertheless, systematic investigations of the influence of exercise therapy on older men and women enrolled in cardiac rehabilitation remain sparse...
  24. ncbi request reprint Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORD-EYE)
    Emily Y Chew
    Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 1204, USA
    Am J Cardiol 99:103i-111i. 2007
    ..These data will provide valuable information regarding the effects of medical treatment on the prevention and progression of DR...
  25. ncbi request reprint Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Am J Clin Nutr 82:428-34. 2005
    ..Age-related body-composition changes are associated with health-related outcomes in elders. This relation may be explained by inflammation and hemostatic abnormalities...
  26. ncbi request reprint Activity of 11beta-hydroxysteroid dehydrogenase type 2 in normotensive blacks and whites
    R Ravi Shankar
    Indiana University School of Medicine Indianapolis, Indiana, USA
    Ethn Dis 15:407-10. 2005
    ..We tested the hypothesis that less activity of the enzyme 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2) is present in Blacks than in Whites...
  27. ncbi request reprint Age, body mass index, and gender differences in sacroiliac joint pathology
    Robert W Irwin
    Department of Rehabilitation Medicine, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Am J Phys Med Rehabil 86:37-44. 2007
    ..To evaluate the correlation between age, gender, and body mass index as they relate to sacroiliac joint pathology diagnosed by dual comparative local anesthetic blocks...