Research Topics
Species | Jadranka LoncarekSummaryAffiliation: Wadsworth Center Country: USA Publications
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Detail Information
Publications
Laser microsurgery in the GFP era: a cell biologist's perspectiveValentin Magidson
Division of Molecular Medicine, Wadsworth Center, Albany, New York 12201, USA
Methods Cell Biol 82:239-66. 2007..Our major thesis is that the limitations of the technology are no longer at the level of the laser, microscope, or software, but instead only in defining creative questions and in visualizing the target to be destroyed...- Ab ovo or de novo? Mechanisms of centriole duplicationJadranka Loncarek
Division of Translational Medicine, Wadsworth Center, New York State Department of Health, Albany, New York, 12201 0509, USA
Mol Cells 27:135-42. 2009..Here we review key proteins involved in centriole assembly, compare two major modes of centriole biogenesis, and discuss the mechanisms that ensure stringency of centriole number... - Centriole reduplication during prolonged interphase requires procentriole maturation governed by Plk1Jadranka Loncarek
Division of Translational Medicine, Wadsworth Center, New York State Department of Health, Albany, NY 12201 0509, USA
Curr Biol 20:1277-82. 2010..Activation of Plk1 during late S/G2 induces procentriole maturation, and after this point, the centriole cycle can be completed autonomously, even in the absence of cell-cycle progression... - The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomesCHRISTOPHER B O'CONNELL
Division of Molecular Medicine, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA
J Cell Biol 183:29-36. 2008..Thus, kinetochore attachment to microtubules is sufficient to satisfy the SAC even in the absence of interkinetochore tension... - The spatial arrangement of chromosomes during prometaphase facilitates spindle assemblyValentin Magidson
Wadsworth Center, New York State Department of Health, Albany, NY 12201 509, USA
Cell 146:555-67. 2011..Thus, spindle formation involves a previously overlooked stage of chromosome prepositioning which promotes formation of amphitelic attachments... - Extra centrosomes and/or chromosomes prolong mitosis in human cellsZhenye Yang
Division of Molecular Medicine, Wadsworth Center, N Y S Department of Health, Empire State Plaza, Albany, New York 12201 0509, USA
Nat Cell Biol 10:748-51. 2008..Thus mitosis can be prolonged by non-genetic means and extra chromosomes and centrosomes probably contribute to the elevated mitotic index seen in many tumours... - Control of daughter centriole formation by the pericentriolar materialJadranka Loncarek
Division of Molecular Medicine, Wadsworth Center, Albany, New York State Department of Health, Albany, New York 12201 0509, USA
Nat Cell Biol 10:322-8. 2008..We propose that that the size of the PCM cloud associated with the mother centriole restricts the number of daughters that can form simultaneously... - Relative contributions of chromatin and kinetochores to mitotic spindle assemblyCHRISTOPHER B O'CONNELL
Division of Translational Medicine, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA
J Cell Biol 187:43-51. 2009..These results support a model in which kinetochores play the dominant role in the chromosome-mediated pathway of mitotic spindle assembly... - Concerted effort of centrosomal and Golgi-derived microtubules is required for proper Golgi complex assembly but not for maintenanceTatiana Vinogradova
Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Mol Biol Cell 23:820-33. 2012..Our data indicate that centrosomal MTs complement Golgi self-organization for proper Golgi assembly and motile-cell polarization... - The centromere geometry essential for keeping mitosis error free is controlled by spindle forcesJadranka Loncarek
Division of Molecular Medicine, Wadsworth Center, Albany, New York State Department of Health, Albany, New York 12201 0509, USA
Nature 450:745-9. 2007..Thus, proper architecture of the centromere makes an important contribution to achieving high fidelity of chromosome segregation...