R Grassucci

Summary

Affiliation: Wadsworth Center
Country: USA

Publications

  1. ncbi request reprint Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy
    I S Gabashvili
    Wadsworth Center, Howard Hughes Medical Institute, Department of Biomedical Sciences, State University of New York at Albany NY 12201 0509, USA
    J Mol Biol 286:1285-91. 1999
  2. pmc Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA
    I S Gabashvili
    The Wadsworth Center, State University of New York at Albany, 12201 0509, USA
    EMBO J 18:6501-7. 1999
  3. ncbi request reprint A model of the translational apparatus based on a three-dimensional reconstruction of the Escherichia coli ribosome
    J Frank
    Wadsworth Center, New York State, Department of Health, NY 12201 0509, USA
    Biochem Cell Biol 73:757-65. 1995
  4. pmc Native 3D structure of eukaryotic 80s ribosome: morphological homology with E. coli 70S ribosome
    A Verschoor
    Wadsworth Center, New York State Department of Health 12201 0509, USA
    J Cell Biol 133:495-505. 1996
  5. ncbi request reprint Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex
    R Beckmann
    Howard Hughes Medical Institute, Laboratory of Cell Biology, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 278:2123-6. 1997
  6. ncbi request reprint The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22
    I S Gabashvili
    Wadsworth Center, State University of New York at Albany, P O Box 509, Albany, NY 12201, USA
    Mol Cell 8:181-8. 2001

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy
    I S Gabashvili
    Wadsworth Center, Howard Hughes Medical Institute, Department of Biomedical Sciences, State University of New York at Albany NY 12201 0509, USA
    J Mol Biol 286:1285-91. 1999
    ..This result suggests the existence of dynamic properties of the 30 S subunit that might be required for facilitating its interactions with mRNA, tRNA and other ligands during protein biosynthesis...
  2. pmc Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA
    I S Gabashvili
    The Wadsworth Center, State University of New York at Albany, 12201 0509, USA
    EMBO J 18:6501-7. 1999
    ..This significantly affects the topography of the A-site tRNA-binding region on the 30S subunit and thereby explains changes in tRNA affinity for the ribosome and fidelity of decoding mRNA...
  3. ncbi request reprint A model of the translational apparatus based on a three-dimensional reconstruction of the Escherichia coli ribosome
    J Frank
    Wadsworth Center, New York State, Department of Health, NY 12201 0509, USA
    Biochem Cell Biol 73:757-65. 1995
    ..From an interpretation of these clues in the light of existing knowledge, a plausible model for the locations and interactions of key components of protein synthesis is suggested...
  4. pmc Native 3D structure of eukaryotic 80s ribosome: morphological homology with E. coli 70S ribosome
    A Verschoor
    Wadsworth Center, New York State Department of Health 12201 0509, USA
    J Cell Biol 133:495-505. 1996
    ..This may be equated with a close contact of the 18S and 28S rRNAs in the translational domain centered on the upper subunit:subunit interface...
  5. ncbi request reprint Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex
    R Beckmann
    Howard Hughes Medical Institute, Laboratory of Cell Biology, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 278:2123-6. 1997
    ....
  6. ncbi request reprint The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22
    I S Gabashvili
    Wadsworth Center, State University of New York at Albany, P O Box 509, Albany, NY 12201, USA
    Mol Cell 8:181-8. 2001
    ....