Anne Dreiem

Summary

Affiliation: Wadsworth Center
Country: USA

Publications

  1. pmc Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent
    Anne Dreiem
    New York State Department of Health, Wadsworth Center, Albany, NY 12201, USA
    Neurotoxicology 28:720-6. 2007
  2. ncbi Thiophene is toxic to cerebellar granule cells in culture after bioactivation by rat liver enzymes
    Anne Dreiem
    Norwegian Defence Research Establishment, Division for Protection and Materiel, P O Box 25, N 2027 Kjeller, Norway
    Neurotoxicology 25:959-66. 2004
  3. ncbi Organic solvent-induced cell death in rat cerebellar granule cells: structure dependence of c10 hydrocarbons and relationship to reactive oxygen species formation
    Anne Dreiem
    Norwegian Defence Research Establishment, Kjeller, Norway
    Neurotoxicology 26:321-30. 2005
  4. ncbi The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent
    Anne Dreiem
    New York State Department of Health, Wadsworth Center, Albany, New York, 12201, USA
    Toxicol Sci 87:156-62. 2005
  5. doi Methylmercury inhibits dopaminergic function in rat pup synaptosomes in an age-dependent manner
    Anne Dreiem
    Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, NY 12201, USA
    Neurotoxicol Teratol 31:312-7. 2009
  6. pmc Polychlorinated biphenyls and polybrominated diphenyl ethers alter striatal dopamine neurochemistry in synaptosomes from developing rats in an additive manner
    Anne Dreiem
    Wadsworth Center, New York State Department of Health, Albany, New York 12201, USA
    Toxicol Sci 118:150-9. 2010
  7. ncbi Involvement of the extracellular signal regulated kinase pathway in hydrocarbon-induced reactive oxygen species formation in human neutrophil granulocytes
    Anne Dreiem
    Norwegian Defence Research Establishment, Division for Protection and Materiel, Kjeller, Norway
    Toxicol Appl Pharmacol 190:102-10. 2003

Detail Information

Publications7

  1. pmc Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent
    Anne Dreiem
    New York State Department of Health, Wadsworth Center, Albany, NY 12201, USA
    Neurotoxicology 28:720-6. 2007
    ....
  2. ncbi Thiophene is toxic to cerebellar granule cells in culture after bioactivation by rat liver enzymes
    Anne Dreiem
    Norwegian Defence Research Establishment, Division for Protection and Materiel, P O Box 25, N 2027 Kjeller, Norway
    Neurotoxicology 25:959-66. 2004
    ..These findings support the hypothesis that thiophene requires metabolism to produce the ultimate toxicant, and that the cytochrome P450 enzyme system is involved in the metabolism...
  3. ncbi Organic solvent-induced cell death in rat cerebellar granule cells: structure dependence of c10 hydrocarbons and relationship to reactive oxygen species formation
    Anne Dreiem
    Norwegian Defence Research Establishment, Kjeller, Norway
    Neurotoxicology 26:321-30. 2005
    ..The significance of ROS formation in relation to cell death is discussed...
  4. ncbi The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent
    Anne Dreiem
    New York State Department of Health, Wadsworth Center, Albany, New York, 12201, USA
    Toxicol Sci 87:156-62. 2005
    ..These age-dependent differences in susceptibility to MeHg are most likely due to a less efficient ROS detoxifying system and lower activity of mitochondrial enzymes in tissue from young animals...
  5. doi Methylmercury inhibits dopaminergic function in rat pup synaptosomes in an age-dependent manner
    Anne Dreiem
    Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, NY 12201, USA
    Neurotoxicol Teratol 31:312-7. 2009
    ..These results demonstrate that MeHg affects the dopaminergic system during early development; it thus may contribute to the neurobehavioral effects seen in MeHg-exposed children...
  6. pmc Polychlorinated biphenyls and polybrominated diphenyl ethers alter striatal dopamine neurochemistry in synaptosomes from developing rats in an additive manner
    Anne Dreiem
    Wadsworth Center, New York State Department of Health, Albany, New York 12201, USA
    Toxicol Sci 118:150-9. 2010
    ..Because the effects of these contaminants are additive, it is necessary to take into account the cumulative exposure to organohalogen contaminants such as PCBs and PBDEs during risk assessment...
  7. ncbi Involvement of the extracellular signal regulated kinase pathway in hydrocarbon-induced reactive oxygen species formation in human neutrophil granulocytes
    Anne Dreiem
    Norwegian Defence Research Establishment, Division for Protection and Materiel, Kjeller, Norway
    Toxicol Appl Pharmacol 190:102-10. 2003
    ..Based on these findings we propose a mechanism involving tyrosine kinases, PI3 kinase, and the ERK1/2 pathway, leading to activation of the NADPH oxidase and production of ROS in neutrophils stimulated by organic solvents...