VISHNU P CHATURVEDI

Summary

Affiliation: Wadsworth Center
Country: USA

Publications

  1. pmc Collaborative study of the NCCLS and flow cytometry methods for antifungal susceptibility testing of Candida albicans
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, 12208 2002, USA
    J Clin Microbiol 42:2249-51. 2004
  2. pmc Cryptococcus gattii in AIDS patients, southern California
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Emerg Infect Dis 11:1686-92. 2005
  3. pmc Extracellular fibrils of pathogenic yeast Cryptococcus gattii are important for ecological niche, murine virulence and human neutrophil interactions
    Deborah J Springer
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e10978. 2010
  4. pmc Projecting global occurrence of Cryptococcus gattii
    Deborah J Springer
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 16:14-20. 2010
  5. pmc Clonal genotype of Geomyces destructans among bats with White Nose Syndrome, New York, USA
    Sunanda S Rajkumar
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 17:1273-6. 2011
  6. pmc Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 6:e17032. 2011
  7. doi Cryptococcus gattii comparative genomics and transcriptomics: a NIH/NIAID White Paper
    V Chaturvedi
    New York State Department of Health, Wadsworth Center, Albany, NY, USA
    Mycopathologia 173:367-73. 2012
  8. pmc Molecular characterization, biofilm analysis and experimental biofouling study of Fusarium isolates from recent cases of fungal keratitis in New York State
    Madhu Dyavaiah
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    BMC Ophthalmol 7:1. 2007
  9. pmc Coccidioidomycosis in New York State
    V Chaturvedi
    New York State Department of Health, Albany, New York 12208 2002, USA
    Emerg Infect Dis 6:25-9. 2000
  10. pmc Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
    Antimicrob Agents Chemother 52:1500-2. 2008

Research Grants

  1. Cryptococcus gatti mating 1oci; mapping and gene study
    Vishnu Chaturvedi; Fiscal Year: 2004

Collaborators

Detail Information

Publications34

  1. pmc Collaborative study of the NCCLS and flow cytometry methods for antifungal susceptibility testing of Candida albicans
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, 12208 2002, USA
    J Clin Microbiol 42:2249-51. 2004
    ..The same isolates were tested blinded at center 2 (C2) by NCCLS and flow cytometry (FC) methods. The agreement between NCCLS and FC methods ranged from 96 to 99%...
  2. pmc Cryptococcus gattii in AIDS patients, southern California
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Emerg Infect Dis 11:1686-92. 2005
    ..The high prevalence of Cg was noteworthy, in view of its sporadic reports from AIDS patients in North America and its recent emergence as a primary pathogen on Vancouver Island, Canada...
  3. pmc Extracellular fibrils of pathogenic yeast Cryptococcus gattii are important for ecological niche, murine virulence and human neutrophil interactions
    Deborah J Springer
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e10978. 2010
    ..Such ecological adaptation of C. gattii could play roles in enhanced virulence in mammalian hosts at least initially via inhibition of host PMN- mediated killing...
  4. pmc Projecting global occurrence of Cryptococcus gattii
    Deborah J Springer
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 16:14-20. 2010
    ..gattii especially from decayed hollows suggesting a possible ecologic niche. This pathogen merits more attention so its environmental occurrence and role in cryptococcosis can be accurately determined...
  5. pmc Clonal genotype of Geomyces destructans among bats with White Nose Syndrome, New York, USA
    Sunanda S Rajkumar
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 17:1273-6. 2011
    ..Multiple gene genealogic analyses were conducted on 16 fungal isolates from diverse sites in New York State during 2008-2010. The results are consistent with the clonal dispersal of a single G. destructans genotype...
  6. pmc Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 6:e17032. 2011
    ..Our results could provide a theoretical basis for future strategies aimed at the rehabilitation of most affected bat species and for decontamination of Gd in the cave environment...
  7. doi Cryptococcus gattii comparative genomics and transcriptomics: a NIH/NIAID White Paper
    V Chaturvedi
    New York State Department of Health, Wadsworth Center, Albany, NY, USA
    Mycopathologia 173:367-73. 2012
    ....
  8. pmc Molecular characterization, biofilm analysis and experimental biofouling study of Fusarium isolates from recent cases of fungal keratitis in New York State
    Madhu Dyavaiah
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    BMC Ophthalmol 7:1. 2007
    ..To characterize Fusarium isolates from recent cases of fungal keratitis in contact lens wearers, and to investigate fungal association with MoistureLoc solution...
  9. pmc Coccidioidomycosis in New York State
    V Chaturvedi
    New York State Department of Health, Albany, New York 12208 2002, USA
    Emerg Infect Dis 6:25-9. 2000
    ..Increased awareness among health-care providers should improve timely diagnosis of coccidioidomycosis and prevention of associated illnesses and deaths among patients in nondisease-endemic areas...
  10. pmc Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
    Antimicrob Agents Chemother 52:1500-2. 2008
    ..All drug combinations yielded MICs lower than the MICs of any two drugs tested singly, and combinations of AMB, PSC, CSP, and VRC were indifferent (no antagonism) by summations of fractional inhibitory concentration...
  11. pmc Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS)
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA
    PLoS ONE 5:e10783. 2010
    ..The fungus has been recovered sparsely despite plentiful availability of afflicted animals...
  12. pmc Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:1543-8. 2011
    ..Median ΣFIC values showed a wide dispersion, and interlaboratory agreements were less than 85% in most instances. Additional studies are needed to improve the interlaboratory reproducibility of antifungal combination testing...
  13. pmc Cryptococcus gattii: a resurgent fungal pathogen
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA
    Trends Microbiol 19:564-71. 2011
    ..Increased focus on epidemiology, ecological modeling and host-pathogen interactions is expected to yield a better understanding of this enigmatic yeast, and ultimately lead to better measures for its control...
  14. pmc Molecular genetic analyses of mating pheromones reveal intervariety mating or hybridization in Cryptococcus neoformans
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany 12201 2002, USA
    Infect Immun 70:5225-35. 2002
    ..grubii is unrelated to, highly divergent from, or rarer than that in C. neoformans var. neoformans. These observations could form the basis for future studies on the role of intervariety mating in C. neoformans biology and virulence...
  15. ncbi Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Mol Microbiol 55:1782-800. 2005
    ..Thus, SOD1p and SOD2p play distinct roles in the biology and virulence of Cn var. gattii via independent modes of action...
  16. ncbi Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208 2002, USA
    Mol Microbiol 47:1681-94. 2003
    ..This report constitutes the first instance in which superoxide dismutase has been directly implicated in the virulence of a fungal pathogen...
  17. pmc Collaborative study of antibiotic medium 3 and flow cytometry for identification of amphotericin B-resistant Candida isolates
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, 12208 2002, USA
    J Clin Microbiol 42:2252-4. 2004
    ..These isolates were tested at center 2 by AM3 test and flow cytometry (FC). The agreements (C1-C2) were 90% for AM3 test and FC and 73% for the AM3 tests...
  18. pmc Transcription factor STE12alpha has distinct roles in morphogenesis, virulence, and ecological fitness of the primary pathogenic yeast Cryptococcus gattii
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, New York 12201 2002, USA
    Eukaryot Cell 5:1065-80. 2006
    ..Thus, STE12alpha plays distinct roles in C. gattii morphogenesis, virulence, and ecological fitness...
  19. pmc Flow cytometry antifungal susceptibility testing of Aspergillus fumigatus and comparison of mode of action of voriconazole vis-à-vis amphotericin B and itraconazole
    Rama Ramani
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York 12208, USA
    Antimicrob Agents Chemother 47:3627-9. 2003
    ..FC results after 4 h correlated well with MICs obtained by the NCCLS M38-A method; voriconazole exhibited fungicidal activity, albeit to a lesser extent than amphotericin B, but to a greater extent than itraconazole...
  20. ncbi Genomic organization and expression of 23 new genes from MATalpha locus of Cryptococcus neoformans var. gattii
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY, USA
    Biochem Biophys Res Commun 326:233-41. 2005
    ..gattii strains in a distinct clade. The identification of the largest number, thus far, of var. gattii structural genes should set the stage for future molecular pathogenesis studies...
  21. ncbi Application of fluorescent probes to study structural changes in Aspergillus fumigatus exposed to amphotericin B, itraconazole, and voriconazole
    Madhurama Gangwar
    Mycology Laboratory, Wadsworth Center, NYSDOH, 120 New Scotland Ave, Albany, NY 12208 2002, USA
    Mycopathologia 162:103-9. 2006
    ..Thus, AB, IZ, and VZ induced gross organelle defects in A. fumigatus nuclei, mitochondria, and cell wall, which were consistent with respective MICs of antifungals used...
  22. ncbi Selection of optimal host strain for molecular pathogenesis studies on Cryptococcus gattii
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 160:207-15. 2005
    ..Based on these observations, we conclude that NIH444 should remain the strain of choice for understanding Cg pathogenesis, especially on the North American continent...
  23. ncbi The Ess1 prolyl isomerase is dispensable for growth but required for virulence in Cryptococcus neoformans
    Ping Ren
    Molecular Genetics Program, Wadsworth Center, New York State Department of Health, State University of New York, Albany, NY 12208, USA
    Microbiology 151:1593-605. 2005
    ..This is supported by the finding that ess1 mutants were hypersensitive to cyclosporin A. C. neoformans might therefore be a useful organism in which to investigate crosstalk among different families of prolyl isomerases...
  24. ncbi An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic marker
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 162:401-9. 2006
    ..This strategy was successfully used for the generation of Cg can2+CAN2/URA5 homologous reconstituted strains, which grew in ambient air to the wild-type level while can2 mutant exhibited severe growth defect under similar conditions...
  25. pmc Prospective, multicenter surveillance study of Candida glabrata: fluconazole and itraconazole susceptibility profiles in bloodstream, invasive, and colonizing strains and differences between isolates from three urban teaching hospitals in New York City (C
    Amar Safdar
    Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Antimicrob Agents Chemother 46:3268-72. 2002
    ..glabrata organisms isolated from hospitals in the same geographic region emphasizes the significance of periodic susceptibility surveillance programs for individual institutions, especially those providing care to patients at risk...
  26. pmc Proficiency testing program for clinical laboratories performing antifungal susceptibility testing of pathogenic yeast species
    Rama Ramani
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York at Albany, Albany, New York 12201 2002, USA
    J Clin Microbiol 41:1143-6. 2003
    ..It is concluded that a suitably designed PTP could adequately monitor the competence of clinical laboratories performing antifungal susceptibility testing...
  27. ncbi The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility
    Zhong Li
    Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany, New York 12201 0509, USA
    Biochemistry 44:6180-9. 2005
    ..Together, these results suggest that CaEss1 might constitute a useful antifungal drug target, and that structural differences between the fungal and human enzymes could be exploited for drug design...
  28. ncbi Antifungal susceptibility profiles of Coccidioides immitis and Coccidioides posadasii from endemic and non-endemic areas
    Rama Ramani
    New York State Department of Health, Mycology Laboratory, Wadsworth Center, 120 New Scotland Ave, Albany, New York 12208 2002, USA
    Mycopathologia 163:315-9. 2007
    ..immitis and C. posadasii isolates. In conclusion, current methods for antifungal susceptibility testing yield reproducible profiles for Coccidioides species, which appear to be highly susceptible to most antifungal agents...
  29. pmc The Ess1 prolyl isomerase is required for growth and morphogenetic switching in Candida albicans
    Gina Devasahayam
    Molecular Genetics Program, Wadsworth Center, New York State Department of Health, Albany, New York 12208, USA
    Genetics 160:37-48. 2002
    ..Given that switching is important for virulence of C. albicans, inhibitors of Ess1 might be useful as antifungal agents...
  30. pmc Evaluations of shorter exposures of contact lens cleaning solutions against Fusarium oxysporum species complex and Fusarium solani species complex to simulate inappropriate usage
    Rama Ramani
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12201 2002, USA
    Antimicrob Agents Chemother 55:2265-75. 2011
    ..This study provides additional support for possible roles that improper lens cleaning regimens and fungal biofilms could play as predisposing factors for Fusarium keratitis...
  31. pmc Evaluation of new medium for identification of dermatophytes and primary dimorphic pathogens
    Sally Gromadzki
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York 12208 2002, USA
    J Clin Microbiol 41:467-8. 2003
    ..Many dimorphic pathogenic fungi also tested positive at both incubation temperatures. Thus, DIM has limited usefulness for presumptive identification of dermatophytes...
  32. pmc Use of paraffin-embedded tissue for identification of Saccharomyces cerevisiae in a baker's lung nodule by fungal PCR and nucleotide sequencing
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, SUNY School of Public Health, University at Albany, Albany, NY 12201 2002, USA
    J Clin Microbiol 42:2840-2. 2004
    ..PCR assay of paraffin-embedded tissue and nucleotide sequencing with ribosomal ITS1-ITS2 universal primers revealed the presence of Saccharomyces cerevisiae...
  33. pmc Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropenia
    Mayssa M Abuali
    Pediatric Infectious Diseases, Mount Sinai Medical Center, New York, New York, USA
    J Clin Microbiol 47:4176-9. 2009
    ..The patient first developed an R. variabilis var. regularior palate infection and later developed a cutaneous H. aspergillata infection while on posaconazole and caspofungin therapy...

Research Grants1

  1. Cryptococcus gatti mating 1oci; mapping and gene study
    Vishnu Chaturvedi; Fiscal Year: 2004
    ..abstract_text> ..