Research Topics
| VISHNU P CHATURVEDISummaryAffiliation: Wadsworth Center Country: USA Publications
Research Grants
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Detail Information
Publications
Collaborative study of the NCCLS and flow cytometry methods for antifungal susceptibility testing of Candida albicansVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, 12208 2002, USA
J Clin Microbiol 42:2249-51. 2004..The same isolates were tested blinded at center 2 (C2) by NCCLS and flow cytometry (FC) methods. The agreement between NCCLS and FC methods ranged from 96 to 99%...
Cryptococcus gattii comparative genomics and transcriptomics: a NIH/NIAID White PaperV Chaturvedi
New York State Department of Health, Wadsworth Center, Albany, NY, USA
Mycopathologia 173:367-73. 2012....- Molecular characterization, biofilm analysis and experimental biofouling study of Fusarium isolates from recent cases of fungal keratitis in New York StateMadhu Dyavaiah
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
BMC Ophthalmol 7:1. 2007..To characterize Fusarium isolates from recent cases of fungal keratitis in contact lens wearers, and to investigate fungal association with MoistureLoc solution... - Cryptococcus gattii: a resurgent fungal pathogenVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA
Trends Microbiol 19:564-71. 2011..Increased focus on epidemiology, ecological modeling and host-pathogen interactions is expected to yield a better understanding of this enigmatic yeast, and ultimately lead to better measures for its control... - Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosisVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
Antimicrob Agents Chemother 55:1543-8. 2011..Median ΣFIC values showed a wide dispersion, and interlaboratory agreements were less than 85% in most instances. Additional studies are needed to improve the interlaboratory reproducibility of antifungal combination testing... - Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS)Vishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA
PLoS ONE 5:e10783. 2010..The fungus has been recovered sparsely despite plentiful availability of afflicted animals... - Multilaboratory testing of antifungal combinations against a quality control isolate of Candida kruseiVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA
Antimicrob Agents Chemother 52:1500-2. 2008..All drug combinations yielded MICs lower than the MICs of any two drugs tested singly, and combinations of AMB, PSC, CSP, and VRC were indifferent (no antagonism) by summations of fractional inhibitory concentration... - Coccidioidomycosis in New York StateV Chaturvedi
New York State Department of Health, Albany, New York 12208 2002, USA
Emerg Infect Dis 6:25-9. 2000..Increased awareness among health-care providers should improve timely diagnosis of coccidioidomycosis and prevention of associated illnesses and deaths among patients in nondisease-endemic areas... - Molecular genetic analyses of mating pheromones reveal intervariety mating or hybridization in Cryptococcus neoformansVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany 12201 2002, USA
Infect Immun 70:5225-35. 2002..grubii is unrelated to, highly divergent from, or rarer than that in C. neoformans var. neoformans. These observations could form the basis for future studies on the role of intervariety mating in C. neoformans biology and virulence... 
Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulenceSrinivas D Narasipura
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208-2002, USA
Mol Microbiol 55:1782-800. 2005..Thus, SOD1p and SOD2p play distinct roles in the biology and virulence of Cn var. gattii via independent modes of action...- Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulenceSrinivas D Narasipura
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208-2002, USA
Mol Microbiol 47:1681-94. 2003..This report constitutes the first instance in which superoxide dismutase has been directly implicated in the virulence of a fungal pathogen... - Collaborative study of antibiotic medium 3 and flow cytometry for identification of amphotericin B-resistant Candida isolatesVishnu Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, 12208 2002, USA
J Clin Microbiol 42:2252-4. 2004..These isolates were tested at center 2 by AM3 test and flow cytometry (FC). The agreements (C1-C2) were 90% for AM3 test and FC and 73% for the AM3 tests... - Cryptococcus gattii in AIDS patients, southern CaliforniaSudha Chaturvedi
Mycology Laboratory, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208-2002, USA
Emerg Infect Dis 11:1686-92. 2005..The high prevalence of Cg was noteworthy, in view of its sporadic reports from AIDS patients in North America and its recent emergence as a primary pathogen on Vancouver Island, Canada... - Flow cytometry antifungal susceptibility testing of Aspergillus fumigatus and comparison of mode of action of voriconazole vis-Ã -vis amphotericin B and itraconazoleRama Ramani
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York 12208, USA
Antimicrob Agents Chemother 47:3627-9. 2003..FC results after 4 h correlated well with MICs obtained by the NCCLS M38-A method; voriconazole exhibited fungicidal activity, albeit to a lesser extent than amphotericin B, but to a greater extent than itraconazole... - Genomic organization and expression of 23 new genes from MATalpha locus of Cryptococcus neoformans var. gattiiPing Ren
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY, USA
Biochem Biophys Res Commun 326:233-41. 2005..gattii strains in a distinct clade. The identification of the largest number, thus far, of var. gattii structural genes should set the stage for future molecular pathogenesis studies... - Transcription factor STE12alpha has distinct roles in morphogenesis, virulence, and ecological fitness of the primary pathogenic yeast Cryptococcus gattiiPing Ren
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, New York 12201-2002, USA
Eukaryot Cell 5:1065-80. 2006..Thus, STE12alpha plays distinct roles in C. gattii morphogenesis, virulence, and ecological fitness... - An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic markerSrinivas D Narasipura
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208-2002, USA
Mycopathologia 162:401-9. 2006..This strategy was successfully used for the generation of Cg can2+CAN2/URA5 homologous reconstituted strains, which grew in ambient air to the wild-type level while can2 mutant exhibited severe growth defect under similar conditions... - Application of fluorescent probes to study structural changes in Aspergillus fumigatus exposed to amphotericin B, itraconazole, and voriconazoleMadhurama Gangwar
Mycology Laboratory, Wadsworth Center, NYSDOH, 120 New Scotland Ave, Albany, NY 12208 - 2002, USA
Mycopathologia 162:103-9. 2006..Thus, AB, IZ, and VZ induced gross organelle defects in A. fumigatus nuclei, mitochondria, and cell wall, which were consistent with respective MICs of antifungals used... - Selection of optimal host strain for molecular pathogenesis studies on Cryptococcus gattiiSudha Chaturvedi
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
Mycopathologia 160:207-15. 2005..Based on these observations, we conclude that NIH444 should remain the strain of choice for understanding Cg pathogenesis, especially on the North American continent... - The Ess1 prolyl isomerase is dispensable for growth but required for virulence in Cryptococcus neoformansPing Ren
Molecular Genetics Program, Wadsworth Center, New York State Department of Health, State University of New York, Albany, NY 12208, USA
Microbiology 151:1593-605. 2005..This is supported by the finding that ess1 mutants were hypersensitive to cyclosporin A. C. neoformans might therefore be a useful organism in which to investigate crosstalk among different families of prolyl isomerases... - Prospective, multicenter surveillance study of Candida glabrata: fluconazole and itraconazole susceptibility profiles in bloodstream, invasive, and colonizing strains and differences between isolates from three urban teaching hospitals in New York City (CAmar Safdar
Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Antimicrob Agents Chemother 46:3268-72. 2002..glabrata organisms isolated from hospitals in the same geographic region emphasizes the significance of periodic susceptibility surveillance programs for individual institutions, especially those providing care to patients at risk... - Extracellular fibrils of pathogenic yeast Cryptococcus gattii are important for ecological niche, murine virulence and human neutrophil interactionsDeborah J Springer
Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
PLoS ONE 5:e10978. 2010..Such ecological adaptation of C. gattii could play roles in enhanced virulence in mammalian hosts at least initially via inhibition of host PMN- mediated killing... - Proficiency testing program for clinical laboratories performing antifungal susceptibility testing of pathogenic yeast speciesRama Ramani
Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York at Albany, Albany, New York 12201-2002, USA
J Clin Microbiol 41:1143-6. 2003..It is concluded that a suitably designed PTP could adequately monitor the competence of clinical laboratories performing antifungal susceptibility testing... - The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobilityZhong Li
Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany, New York 12201-0509, USA
Biochemistry 44:6180-9. 2005..Together, these results suggest that CaEss1 might constitute a useful antifungal drug target, and that structural differences between the fungal and human enzymes could be exploited for drug design... - Antifungal susceptibility profiles of Coccidioides immitis and Coccidioides posadasii from endemic and non-endemic areasRama Ramani
New York State Department of Health, Mycology Laboratory, Wadsworth Center, 120 New Scotland Ave, Albany, New York 12208 2002, USA
Mycopathologia 163:315-9. 2007..immitis and C. posadasii isolates. In conclusion, current methods for antifungal susceptibility testing yield reproducible profiles for Coccidioides species, which appear to be highly susceptible to most antifungal agents... - The Ess1 prolyl isomerase is required for growth and morphogenetic switching in Candida albicansGina Devasahayam
Molecular Genetics Program, Wadsworth Center, New York State Department of Health, Albany, New York 12208, USA
Genetics 160:37-48. 2002..Given that switching is important for virulence of C. albicans, inhibitors of Ess1 might be useful as antifungal agents... - Projecting global occurrence of Cryptococcus gattiiDeborah J Springer
New York State Department of Health, Albany, New York, USA
Emerg Infect Dis 16:14-20. 2010..gattii especially from decayed hollows suggesting a possible ecologic niche. This pathogen merits more attention so its environmental occurrence and role in cryptococcosis can be accurately determined... - Evaluations of shorter exposures of contact lens cleaning solutions against Fusarium oxysporum species complex and Fusarium solani species complex to simulate inappropriate usageRama Ramani
Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12201 2002, USA
Antimicrob Agents Chemother 55:2265-75. 2011..This study provides additional support for possible roles that improper lens cleaning regimens and fungal biofilms could play as predisposing factors for Fusarium keratitis... - Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropeniaMayssa M Abuali
Pediatric Infectious Diseases, Mount Sinai Medical Center, New York, New York, USA
J Clin Microbiol 47:4176-9. 2009..The patient first developed an R. variabilis var. regularior palate infection and later developed a cutaneous H. aspergillata infection while on posaconazole and caspofungin therapy... - Evaluation of new medium for identification of dermatophytes and primary dimorphic pathogensSally Gromadzki
Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York 12208-2002, USA
J Clin Microbiol 41:467-8. 2003..Many dimorphic pathogenic fungi also tested positive at both incubation temperatures. Thus, DIM has limited usefulness for presumptive identification of dermatophytes... - Use of paraffin-embedded tissue for identification of Saccharomyces cerevisiae in a baker's lung nodule by fungal PCR and nucleotide sequencingPing Ren
Mycology Laboratory, Wadsworth Center, New York State Department of Health, SUNY School of Public Health, University at Albany, Albany, NY 12201-2002, USA
J Clin Microbiol 42:2840-2. 2004..PCR assay of paraffin-embedded tissue and nucleotide sequencing with ribosomal ITS1-ITS2 universal primers revealed the presence of Saccharomyces cerevisiae...
Research Grants
- Cryptococcus gatti mating 1oci; mapping and gene studyVishnu Chaturvedi; Fiscal Year: 2004..abstract_text> ..