Richard Wenzel

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. doi Infection control: the case for horizontal rather than vertical interventional programs
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, 1101 East Broad Street, PO Box 980663, Richmond, VA 23298, USA
    Int J Infect Dis 14:S3-5. 2010
  2. pmc Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome
    Alexandre R Marra
    Department of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    BMC Infect Dis 7:42. 2007
  3. ncbi John E. Bennett Forum on Deep Mycoses Study Design 2004: Candidiasis and salvage therapy for aspergillosis
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, 23298, USA
    Clin Infect Dis 41:S369-70. 2005
  4. ncbi Health care-associated infections: major issues in the early years of the 21st century
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Clin Infect Dis 45:S85-8. 2007
  5. ncbi Community-acquired methicillin-resistant Staphylococcus aureus (MRSA): new issues for infection control
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, and Medical College of Virginia Hospitals, 1101 East Broad Street, P O Box 980663, Richmond, VA 23298, USA
    Int J Antimicrob Agents 30:210-2. 2007
  6. ncbi Tigecycline
    Richard Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA
    Nat Rev Drug Discov 4:809-10. 2005
  7. ncbi Clinical practice. Acute bronchitis
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    N Engl J Med 355:2125-30. 2006
  8. pmc Vancomycin susceptibility of oxacillin-resistant Staphylococcus aureus isolates causing nosocomial bloodstream infections
    Sandra M Tallent
    Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298, USA
    J Clin Microbiol 40:2249-50. 2002
  9. ncbi Ramoplanin: a topical lipoglycodepsipeptide antibacterial agent
    Patricia Fulco
    Virginia Commonwealth University, Department of Internal Medicine, Richmond, VA, USA
    Expert Rev Anti Infect Ther 4:939-45. 2006
  10. doi Antibiotic options for treating community-acquired MRSA
    J Patrick Powell
    Department of Pharmacy, VCU Health System, 401 N 12th Street, Box 980042, Richmond, VA 23298 0042, USA
    Expert Rev Anti Infect Ther 6:299-307. 2008

Collaborators

Detail Information

Publications35

  1. doi Infection control: the case for horizontal rather than vertical interventional programs
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, 1101 East Broad Street, PO Box 980663, Richmond, VA 23298, USA
    Int J Infect Dis 14:S3-5. 2010
    ..We suggest that horizontal programs should form the platform of all infection control programs and the key question should be, what is the incremental value of a new vertical program?..
  2. pmc Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome
    Alexandre R Marra
    Department of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    BMC Infect Dis 7:42. 2007
    ..We evaluated the epidemiology, clinical course and outcome of hospital-acquired CDAD in the critical care setting...
  3. ncbi John E. Bennett Forum on Deep Mycoses Study Design 2004: Candidiasis and salvage therapy for aspergillosis
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, 23298, USA
    Clin Infect Dis 41:S369-70. 2005
  4. ncbi Health care-associated infections: major issues in the early years of the 21st century
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Clin Infect Dis 45:S85-8. 2007
    ..Increasing levels of antibiotic resistance and the problems associated with biofilms surrounding prostheses and vascular catheters pose special challenges. These issues and potential solutions are addressed in the present article...
  5. ncbi Community-acquired methicillin-resistant Staphylococcus aureus (MRSA): new issues for infection control
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, and Medical College of Virginia Hospitals, 1101 East Broad Street, P O Box 980663, Richmond, VA 23298, USA
    Int J Antimicrob Agents 30:210-2. 2007
    ..Questions about changing prophylactic and empirical therapy as well as the use of intravenous immunoglobulin for life-threatening infections are addressed...
  6. ncbi Tigecycline
    Richard Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA
    Nat Rev Drug Discov 4:809-10. 2005
  7. ncbi Clinical practice. Acute bronchitis
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    N Engl J Med 355:2125-30. 2006
  8. pmc Vancomycin susceptibility of oxacillin-resistant Staphylococcus aureus isolates causing nosocomial bloodstream infections
    Sandra M Tallent
    Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298, USA
    J Clin Microbiol 40:2249-50. 2002
    ..Only one isolate exhibiting heterotypic resistance was detected. Thus, vancomycin heteroresistance in clinical bloodstream isolates remains rare in the United States...
  9. ncbi Ramoplanin: a topical lipoglycodepsipeptide antibacterial agent
    Patricia Fulco
    Virginia Commonwealth University, Department of Internal Medicine, Richmond, VA, USA
    Expert Rev Anti Infect Ther 4:939-45. 2006
    ..difficile colitis. The clinical value and place in therapy of ramoplanin is dependent upon the results of Phase III trials addressing its utility in suppressing carriage of target organisms in the gastrointestinal tract or in the nares...
  10. doi Antibiotic options for treating community-acquired MRSA
    J Patrick Powell
    Department of Pharmacy, VCU Health System, 401 N 12th Street, Box 980042, Richmond, VA 23298 0042, USA
    Expert Rev Anti Infect Ther 6:299-307. 2008
    ..Clinical trials directly comparing antibiotic options in both out-patient and in-patient settings are needed to enhance recommendations for empiric therapy algorithms...
  11. ncbi Predicting hospital rates of fluoroquinolone-resistant Pseudomonas aeruginosa from fluoroquinolone use in US hospitals and their surrounding communities
    Ronald E Polk
    School of Pharmacy, Department of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
    Clin Infect Dis 39:497-503. 2004
    ..aeruginosa. Levofloxacin was associated with resistance, but ciprofloxacin was not. Most of the variability in resistance rates is explained by volume of fluoroquinolone use, both in the hospital and the surrounding community...
  12. ncbi Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study
    Hilmar Wisplinghoff
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, USA
    Clin Infect Dis 39:309-17. 2004
    ..Nosocomial bloodstream infections (BSIs) are important causes of morbidity and mortality in the United States...
  13. doi Screening for MRSA: a flawed hospital infection control intervention
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA
    Infect Control Hosp Epidemiol 29:1012-8. 2008
    ....
  14. ncbi Preoperative risk factors for nasal carriage of Staphylococcus aureus
    Loreen A Herwaldt
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242 1081, USA
    Infect Control Hosp Epidemiol 25:481-4. 2004
    ..aureus, and eradication of carriage reduces postoperative nosocomial infections caused by it. No study has compared large groups of preoperative carriers and non-carriers to identify factors that are linked to S. aureus nasal carriage...
  15. pmc In vitro susceptibilities of gram-negative bacteria isolated from hospitalized patients in four European countries, Canada, and the United States in 2000-2001 to expanded-spectrum cephalosporins and comparator antimicrobials: implications for therapy
    Richard P Wenzel
    Virginia Commonwealth University, Richmond Focus Technologies, Herndon, Virginia 20171, USA
    Antimicrob Agents Chemother 47:3089-98. 2003
    ..The present study demonstrated that established parenteral expanded-spectrum cephalosporin antimicrobial agents retain significant in vitro activity against many clinically important gram-negative pathogens...
  16. pmc Time to blood culture positivity as a predictor of clinical outcome of Staphylococcus aureus bloodstream infection
    Alexandre R Marra
    A D Williams Clinic, 1201 East Marshall Street, 6th Floor, Room 6 602, P O Box 980019, Richmond, VA 23298, USA
    J Clin Microbiol 44:1342-6. 2006
    ..aureus (OR, 9.3; 95% CI, 1.45 to 59.23), and TTPs of </=12 h (OR, 6.9; 95% CI, 1.07 to 44.66). In this historical cohort study of BSIs due to S. aureus, a TTP of </=12 h was a predictor of the clinical outcome...
  17. ncbi A controlled trial of universal gloving versus contact precautions for preventing the transmission of multidrug-resistant organisms
    Gonzalo M L Bearman
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA
    Am J Infect Control 35:650-5. 2007
    ..Contact precautions are recommended to reduce the transmission of multidrug-resistant organisms. However, the optimal method for control of multidrug-resistant organisms remains unclear...
  18. ncbi Bloodstream infections due to Candida species in the intensive care unit: identifying especially high-risk patients to determine prevention strategies
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    Clin Infect Dis 41:S389-93. 2005
    ..Use of defined risk factors to select patients who are at high risk for candidemia and treatment with effective antibiotics would be an efficient way to reduce infection-related deaths...
  19. ncbi Infection control and the prevention of nosocomial infections in the intensive care unit
    Gonzalo M L Bearman
    Division of Quality HealthCare, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298 0019, USA
    Semin Respir Crit Care Med 27:310-24. 2006
    ..For greatest risk reduction, multifaceted programs ensuring maximal adherence with evidence-based infection control guidelines are needed...
  20. ncbi Bacteremias: a leading cause of death
    Gonzalo M L Bearman
    Internal Medicine, Epidemiology and Community Medicine, Division of Quality HealthCare, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298 0019, USA
    Arch Med Res 36:646-59. 2005
    ..Regrettably, despite advances in treatment and intensive care facilities, mortality remains high...
  21. ncbi A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections
    Loreen A Herwaldt
    Department of Internal Medicine, University of Iowa College of Public Health, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Infect Control Hosp Epidemiol 27:1291-8. 2006
    ..We evaluated 4 important outcomes associated with postoperative nosocomial infection: costs, mortality, excess length of stay, and utilization of healthcare resources...
  22. ncbi The antibiotic pipeline--challenges, costs, and values
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, USA
    N Engl J Med 351:523-6. 2004
  23. pmc Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infections due to enterococci
    Katharine Bar
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
    BMC Infect Dis 6:145. 2006
    ..This study analyzed the inflammatory response of Enterococcal BSI, contrasting infections from vancomycin-resistant and vancomycin-susceptible isolates...
  24. ncbi Treating sepsis
    Richard P Wenzel
    Virginia Commonwealth University, Richmond, VA 23298, USA
    N Engl J Med 347:966-7. 2002
  25. ncbi Managing SARS amidst uncertainty
    Richard P Wenzel
    Department of Internal Medicine, Virginia Commonwealth University, Richmond, USA
    N Engl J Med 348:1947-8. 2003
  26. ncbi Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections
    Trish M Perl
    University of Iowa Colleges of Medicine and Public Health, Iowa City, USA
    N Engl J Med 346:1871-7. 2002
    ..Treatment with mupirocin ointment can reduce the rate of nasal carriage and may prevent postoperative S. aureus infections...
  27. ncbi Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States
    Hilmar Wisplinghoff
    Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50935 Cologne, Germany
    Clin Infect Dis 36:1103-10. 2003
    ..The source of BSI was not determined for 57% of patients. The crude mortality rate was 36% for neutropenic patients and 31% for nonneutropenic patients...
  28. ncbi Nosocomial bloodstream infections in pediatric patients in United States hospitals: epidemiology, clinical features and susceptibilities
    Hilmar Wisplinghoff
    Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Germany
    Pediatr Infect Dis J 22:686-91. 2003
    ....
  29. ncbi Team-based prevention of catheter-related infections
    Richard P Wenzel
    N Engl J Med 355:2781-3. 2006
  30. pmc Comparison of severity of illness scoring systems for patients with nosocomial bloodstream infection due to Pseudomonas aeruginosa
    Alexandre R Marra
    Division of Infectious Diseases, Universidade Federal de Sao Paulo, Brasil UNIFESP EPM Hospital São Paulo HSP, Brazil
    BMC Infect Dis 6:132. 2006
    ..We compared three severity of illness scoring systems for predicting mortality in patients with nBSI due to Pseudomonas aeruginosa...
  31. pmc Comparison of the systemic inflammatory response syndrome between monomicrobial and polymicrobial Pseudomonas aeruginosa nosocomial bloodstream infections
    Alexandre R Marra
    Department of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    BMC Infect Dis 5:94. 2005
    ..The purpose of this study was to compare differences in systemic inflammatory response and mortality between monomicrobial and polymicrobial nBSI with Pseudomonas aeruginosa...
  32. doi Intranasal mupirocin for reduction of Staphylococcus aureus infections in surgical patients with nasal carriage: a systematic review
    Miranda M L Van Rijen
    Laboratory for Microbiology and Infection Control, Amphia Hospital, Location Molengracht, PO Box 90158, 4800 RK Breda, The Netherlands
    J Antimicrob Chemother 61:254-61. 2008
    ..The objective of this review was to assess whether intranasal mupirocin treatment of nasal S. aureus carriers before surgery results in a reduction of the post-operative S. aureus infection rate...
  33. ncbi Listening to SARS: lessons for infection control
    Richard P Wenzel
    Ann Intern Med 139:592-3. 2003
  34. ncbi Patient-to-patient transmission of hepatitis C virus
    Richard P Wenzel
    Ann Intern Med 142:940-1. 2005
  35. ncbi Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Pseudomonas aeruginosa
    Alexandre R Marra
    Division of Infectious Diseases, Brazil UNIFESP EPM Hospital São Paulo HSP, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Infect 53:30-5. 2006
    ..To evaluate relationships between the inflammatory response, clinical course, and outcome of nosocomial BSI due to Pseudomonas aeruginosa...