Jeannine S Strobl

Summary

Affiliation: Virginia Polytechnic Institute and State University
Country: USA

Publications

  1. ncbi request reprint Protein kinase C delta is a prosurvival factor in human breast tumor cell lines
    Meredith A McCracken
    Department of Biochemistry and Molecular Pharmacology, and Genetics and Developmental Biology Program, West Virginia University, Morgantown, West Virginia 26506, USA
    Mol Cancer Ther 2:273-81. 2003
  2. doi request reprint MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 32:7625-32. 2011
  3. ncbi request reprint Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro
    Jeannine S Strobl
    Biomedical Sciences, Edward Via Virginia College of Osteopathic Medicine, Blacksburg, Virginia 24060, USA
    J Parasitol 93:694-700. 2007
  4. doi request reprint Inhibition of Toxoplasma gondii and Plasmodium falciparum infections in vitro by NSC3852, a redox active antiproliferative and tumor cell differentiation agent
    Jeannine S Strobl
    Virginia College of Osteopathic Medicine, Virginia Tech Corporate Research Center, Blacksburg, Virginia 24060, USA
    J Parasitol 95:215-23. 2009
  5. doi request reprint Actions of the anti-cancer drug suberoylanilide hydroxamic acid (SAHA) on human breast cancer cytoarchitecture in silicon microstructures
    Jeannine S Strobl
    Department of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 31:7043-50. 2010
  6. doi request reprint The cytoskeletal organization of breast carcinoma and fibroblast cells inside three dimensional (3-D) isotropic silicon microstructures
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 31:4552-61. 2010
  7. doi request reprint Attachment and response of human fibroblast and breast cancer cells to three dimensional silicon microstructures of different geometries
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomed Microdevices 11:429-41. 2009
  8. doi request reprint Dopamine stimulates propagation of Toxoplasma gondii tachyzoites in human fibroblast and primary neonatal rat astrocyte cell cultures
    Jeannine S Strobl
    Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA
    J Parasitol 98:1296-9. 2012
  9. doi request reprint Method to quantify the effect of passivation layer in bio-impedance sensors
    Shree Narayanan
    The Bradley Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, 24060, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:3783-6. 2009
  10. pmc Cadmium-containing nanoparticles: perspectives on pharmacology and toxicology of quantum dots
    Beverly A Rzigalinski
    Department of Pharmacology, Virginia College of Osteopathic Medicine, NanoNeuroLab, Blacksburg, VA 24060, USA
    Toxicol Appl Pharmacol 238:280-8. 2009

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Protein kinase C delta is a prosurvival factor in human breast tumor cell lines
    Meredith A McCracken
    Department of Biochemistry and Molecular Pharmacology, and Genetics and Developmental Biology Program, West Virginia University, Morgantown, West Virginia 26506, USA
    Mol Cancer Ther 2:273-81. 2003
    ..5 Gy radiation-treated cells. We conclude that PKC delta acts as a prosurvival factor in human breast tumor cells in vitro...
  2. doi request reprint MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 32:7625-32. 2011
    ....
  3. ncbi request reprint Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro
    Jeannine S Strobl
    Biomedical Sciences, Edward Via Virginia College of Osteopathic Medicine, Blacksburg, Virginia 24060, USA
    J Parasitol 93:694-700. 2007
    ..gondii in our in vitro assays. We conclude that the hydroxamic acid class of histone deacetylase inhibitors exhibit potent anti-T. gondii activity in vitro...
  4. doi request reprint Inhibition of Toxoplasma gondii and Plasmodium falciparum infections in vitro by NSC3852, a redox active antiproliferative and tumor cell differentiation agent
    Jeannine S Strobl
    Virginia College of Osteopathic Medicine, Virginia Tech Corporate Research Center, Blacksburg, Virginia 24060, USA
    J Parasitol 95:215-23. 2009
    ..gondii tachyzoites in vitro and that NSC3852 is a potent T. gondii inhibitor that acts by indirect generation of oxidative stress in T. gondii...
  5. doi request reprint Actions of the anti-cancer drug suberoylanilide hydroxamic acid (SAHA) on human breast cancer cytoarchitecture in silicon microstructures
    Jeannine S Strobl
    Department of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 31:7043-50. 2010
    ..We conclude that isotropically etched silicon microstructures comprise microenvironments that discriminate metastatic mammary cancer cells in which cytoskeletal elements reorganized in response to the anti-cancer agent SAHA...
  6. doi request reprint The cytoskeletal organization of breast carcinoma and fibroblast cells inside three dimensional (3-D) isotropic silicon microstructures
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomaterials 31:4552-61. 2010
    ..Our findings are consistent with tensegrity theory. The 3-D microstructures have the potential to probe cytoskeletal-based differences between healthy and diseased cells that can provide biomarkers for diagnostics purposes...
  7. doi request reprint Attachment and response of human fibroblast and breast cancer cells to three dimensional silicon microstructures of different geometries
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomed Microdevices 11:429-41. 2009
    ....
  8. doi request reprint Dopamine stimulates propagation of Toxoplasma gondii tachyzoites in human fibroblast and primary neonatal rat astrocyte cell cultures
    Jeannine S Strobl
    Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, Virginia 24061, USA
    J Parasitol 98:1296-9. 2012
    ..05) increased numbers of intracellular tachyzoites after 24 hr. The role that this increase plays in tachyzoite production under the stimulus of dopamine in the modulation of neural infection in humans awaits further studies...
  9. doi request reprint Method to quantify the effect of passivation layer in bio-impedance sensors
    Shree Narayanan
    The Bradley Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, 24060, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:3783-6. 2009
    ..Thus, the passivation layer needs to be provided a special consideration in future design of the sensor as it can modify the response of the sensor...
  10. pmc Cadmium-containing nanoparticles: perspectives on pharmacology and toxicology of quantum dots
    Beverly A Rzigalinski
    Department of Pharmacology, Virginia College of Osteopathic Medicine, NanoNeuroLab, Blacksburg, VA 24060, USA
    Toxicol Appl Pharmacol 238:280-8. 2009
    ..Finally, we identify critical gaps in our knowledge of cadmium quantum dot toxicity, and how these gaps need to be assessed to enable quantum dot nanotechnology to transit safely from bench to bedside...
  11. ncbi request reprint Geometry-dependent behavior of fibroblast cells in three-dimensional silicon microstructures
    Mehdi Nikkhah
    Virginia Tech MEMS Laboratory, The Bradley Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:6078-81. 2007
    ..The growth rate decline has been utilized as a new method to create patterned cell culture...
  12. doi request reprint Evaluation of the influence of growth medium composition on cell elasticity
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    J Biomech 44:762-6. 2011
    ..The investigation of the effects of culture medium composition on the elastic properties of cells highlights the need to take these effects into consideration when interpreting elasticity measurements in cells grown in different media...
  13. doi request reprint Evaluation of five antischizophrenic agents against Toxoplasma gondii in human cell cultures
    David G Goodwin
    Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia 24061 0342, USA
    J Parasitol 97:148-51. 2011
    ..7 µM, thioridazine had an IC(50) of 1.2 µM, and trifluoperazine had an IC(50) of 3.8 µM. Our study demonstrates that some agents used to treat schizophrenia have the ability to inhibit T. gondii proliferation in cell culture...
  14. doi request reprint Potent induction of total cellular and mitochondrial antioxidants and phase 2 enzymes by cruciferous sulforaphane in rat aortic smooth muscle cells: cytoprotection against oxidative and electrophilic stress
    Hong Zhu
    Division of Biomedical Sciences, Edward Via Virginia College of Osteopathic Medicine, Virginia Tech Corporate Research Center, Blacksburg, VA 24060, USA
    Cardiovasc Toxicol 8:115-25. 2008
    ....
  15. doi request reprint Congenital infection of mice with Toxoplasma gondii induces minimal change in behavior and no change in neurotransmitter concentrations
    David Goodwin
    Via College of Osteopathic Medicine, Virginia Campus, Blacksburg, VA 24060, USA
    J Parasitol 98:706-12. 2012
    ..gondii infection in animals. We were not able, however, to confirm the widely held belief that changes in neurotransmitters result from chronic T. gondii infection of the brain...
  16. doi request reprint Cytoskeletal role in differential adhesion patterns of normal fibroblasts and breast cancer cells inside silicon microenvironments
    Mehdi Nikkhah
    Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Biomed Microdevices 11:585-95. 2009
    ..These 3-D silicon microstructures can be used as a tool to investigate cellular activities in a 3-D architecture and compare cytoskeletal properties of various cell lines...
  17. ncbi request reprint Design, synthesis, and bioactivities of steroid-linked taxol analogues as potential targeted drugs for prostate and breast cancer
    Changhui Liu
    Department of Chemistry, M C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    J Nat Prod 67:152-9. 2004
    ..The corresponding Na and triethanolammonium salts were slightly more cytotoxic than the acid form but were much less cytotoxic than the corresponding ETC...
  18. ncbi request reprint Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model
    Anna R Martirosyan
    Department of Biochemistry and Molecular Pharmacology, West Virginia University, Morgantown, WV 26506, USA
    Biochem Pharmacol 68:1729-38. 2004
    ..We conclude DNA damage and reductions in E2F1 protein are mechanistically important to the differentiation and antiproliferative activities of these quinoline drug candidates...