Thomas J Smith

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. doi request reprint Cost and non-clinical outcomes of palliative care
    Thomas J Smith
    Department of Medicine, Virginia Commonwealth University, Massey Cancer Center, Richmond, Virginia, USA
    J Pain Symptom Manage 38:32-44. 2009
  2. doi request reprint Barriers to effective palliative care for low-income patients in late stages of cancer: report of a study and strategies for defining and conquering the barriers
    Laurie J Lyckholm
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University School of Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    Nurs Clin North Am 45:399-409. 2010
  3. ncbi request reprint Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update
    James L Khatcheressian
    Virginia Cancer Institute, Richmond, VA, USA
    J Clin Oncol 31:961-5. 2013
  4. ncbi request reprint Giving honest information to patients with advanced cancer maintains hope
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 24:521-5. 2010
  5. doi request reprint Exploring hereditary cancer among dying cancer patients--a cross-sectional study of hereditary risk and perceived awareness of DNA testing and banking
    John Martin Quillin
    Massey Cancer Center, Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298 0033, USA
    J Genet Couns 19:497-525. 2010
  6. ncbi request reprint Palliative care consultation in the process of organ donation after cardiac death
    Catherine McVearry Kelso
    Department of Internal Medicine, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23298, USA
    J Palliat Med 10:118-26. 2007
  7. pmc Ischaemic heart disease mortality and years of work in trucking industry workers
    Jaime E Hart
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Occup Environ Med 70:523-8. 2013
  8. pmc Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives
    Lindsay A Dow
    School of Medicine and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 28:299-304. 2010
  9. pmc The role of chemotherapy at the end of life: "when is enough, enough?"
    Sarah Elizabeth Harrington
    Department of Internal Medicine and the Thomas Palliative Care Program, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA
    JAMA 299:2667-78. 2008
  10. ncbi request reprint 'Futile care': what to do when your patient insists on chemotherapy that likely won't help
    James Khatcheressian
    Division of Hematology Oncology, Massey Cancer Center of Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 22:881-8; discussion 893, 896, 898. 2008

Detail Information

Publications51

  1. doi request reprint Cost and non-clinical outcomes of palliative care
    Thomas J Smith
    Department of Medicine, Virginia Commonwealth University, Massey Cancer Center, Richmond, Virginia, USA
    J Pain Symptom Manage 38:32-44. 2009
    ..In collecting and presenting the data to administrators and others, we have found that the simplest approach is the most effective-for example, presenting a few clinical outcomes alongside cost-saving data...
  2. doi request reprint Barriers to effective palliative care for low-income patients in late stages of cancer: report of a study and strategies for defining and conquering the barriers
    Laurie J Lyckholm
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University School of Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    Nurs Clin North Am 45:399-409. 2010
    ....
  3. ncbi request reprint Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update
    James L Khatcheressian
    Virginia Cancer Institute, Richmond, VA, USA
    J Clin Oncol 31:961-5. 2013
    ..To provide recommendations on the follow-up and management of patients with breast cancer who have completed primary therapy with curative intent...
  4. ncbi request reprint Giving honest information to patients with advanced cancer maintains hope
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 24:521-5. 2010
    ..One of the primary reasons stated for witholding this information is to "not take away hope." We could find no study that tested if hope was influenced by honest clinical information...
  5. doi request reprint Exploring hereditary cancer among dying cancer patients--a cross-sectional study of hereditary risk and perceived awareness of DNA testing and banking
    John Martin Quillin
    Massey Cancer Center, Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298 0033, USA
    J Genet Couns 19:497-525. 2010
    ..These conditions are not being recognized upstream and families are losing valuable information...
  6. ncbi request reprint Palliative care consultation in the process of organ donation after cardiac death
    Catherine McVearry Kelso
    Department of Internal Medicine, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23298, USA
    J Palliat Med 10:118-26. 2007
    ....
  7. pmc Ischaemic heart disease mortality and years of work in trucking industry workers
    Jaime E Hart
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Occup Environ Med 70:523-8. 2013
    ..Therefore, the authors examined the association of increasing years of work in jobs with vehicle exhaust exposure and IHD mortality within the cohort...
  8. pmc Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives
    Lindsay A Dow
    School of Medicine and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 28:299-304. 2010
    ..Ten years ago, patients with cancer said they would not like to discuss ADs with their oncologist but would be willing to discuss them with an admitting physician. We assessed whether this point of view still held...
  9. pmc The role of chemotherapy at the end of life: "when is enough, enough?"
    Sarah Elizabeth Harrington
    Department of Internal Medicine and the Thomas Palliative Care Program, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA
    JAMA 299:2667-78. 2008
    ..Approaches to communication about prognosis and treatment options and questions that patients may want to ask are discussed...
  10. ncbi request reprint 'Futile care': what to do when your patient insists on chemotherapy that likely won't help
    James Khatcheressian
    Division of Hematology Oncology, Massey Cancer Center of Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 22:881-8; discussion 893, 896, 898. 2008
    ..In this review, we consider the roles of both the patient and the physician in driving the provision of "futile care" and offer practical steps the oncologist can take to avoid it...
  11. pmc A pilot trial of decision aids to give truthful prognostic and treatment information to chemotherapy patients with advanced cancer
    Thomas J Smith
    Massey Cancer Center of Virginia Commonwealth University, School of Education, VCU School of Medicine, Department of Social and Behavioral Health, and the Virginia Cancer Institute, Richmond, Virginia 23298 0230, USA
    J Support Oncol 9:79-86. 2011
    ..Research is needed to test the findings in a larger sample and measure the outcomes of truthful information on quality of life, quality of care, and costs...
  12. pmc A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders
    Laurel Lyckholm
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Pain Palliat Care Pharmacother 26:111-4. 2012
    ..Zinc at standard doses did not provide significant benefit to taste or smell in patients receiving chemotherapy...
  13. doi request reprint Dexmedetomidine as an adjuvant analgesic for intractable cancer pain
    Seth B Roberts
    Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Palliat Med 14:371-3. 2011
    ..We describe its use as an adjuvant analgesic in a patient with cancer pain refractory to multiple treatment modalities...
  14. doi request reprint Concrete options and ideas for increasing value in oncology care: the view from one trench
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA
    Oncologist 15:65-72. 2010
    ..These actions will likely control costs, but in the short term will cause significant distress among patients, families, and health care practitioners...
  15. doi request reprint Hospital mortality rates: how is palliative care taken into account?
    J Brian Cassel
    Virginia Commonwealth University, Richmond, Virginia, USA
    J Pain Symptom Manage 40:914-25. 2010
    ..To be a fair measure of hospital quality, hospital mortality measures must take patient-level factors, such as goals of care, into account...
  16. ncbi request reprint Identifying supportive and unsupportive responses of others: perspectives of African American and Caucasian cancer patients
    Christina M Grange
    Department of Psychology, Virginia Commonwealth University VCU, 808 W Franklin St, Box 842018, Richmond, VA, 23284, USA
    J Psychosoc Oncol 26:81-99. 2008
    ....
  17. doi request reprint Palliative care consultation and hospital length of stay
    J Brian Cassel
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0037, USA
    J Palliat Med 13:761-7. 2010
    ....
  18. doi request reprint Organ donation after cardiac death from withdrawal of life support in patients with amyotrophic lateral sclerosis
    Thomas J Smith
    Palliative Care Program of Johns Hopkins Medicine, Baltimore, Maryland 21287, USA
    J Palliat Med 15:16-9. 2012
    ..We report DCD in two people with progressive amyotrophic lateral sclerosis (ALS)...
  19. pmc A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients
    Haeseong Park
    Department of Internal Medicine Residency Program, Virginia Commonwealth University Health System, Richmond, VA, USA
    Support Care Cancer 19:859-63. 2011
    ..We tested if magnesium would diminish bothersome hot flashes in breast cancer patients...
  20. doi request reprint Genetics assessment at the end of life: suggestions for implementation in clinic and future research
    John Martin Quillin
    Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0033, USA
    J Palliat Med 11:451-8. 2008
    ..Once the patient has died, the chance to test or bank DNA for common inherited conditions such as breast cancer, colon cancer, cardiovascular disease, etc., is gone...
  21. doi request reprint Concentrating hospital-wide deaths in a palliative care unit: the effect on place of death and system-wide mortality
    J Brian Cassel
    Oncology Service Line, Massey Cancer Center Virginia Commonwealth University, Virginia Commonwealth University Health System, Richmond, Virginia, USA
    J Palliat Med 13:371-4. 2010
    ..Observers were concerned that an active PCU would attract dying patients and worsen comparative mortality rates for Medicare and U.S. News & World Report comparisons...
  22. ncbi request reprint Improving palliative and supportive care in cancer patients
    James Khatcheressian
    Division of Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0230, USA
    Oncology (Williston Park) 19:1365-76; discussion 1377-8, 1381-2, 1384 passim. 2005
    ..Finally, we suggest a practical plan for using symptom assessment scales, listing the problems, and managing them according to algorithms or other predetermined plans...
  23. ncbi request reprint How to use implantable intrathecal drug delivery systems for refractory cancer pain
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University Health System, Richmond, Virginia 23298 0230, USA
    J Support Oncol 1:73-6. 2003
  24. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Oncol Rep 6:291-6. 2004
    ..Given multiple positive small cohort studies and a positive high-power randomized trial, IDDS should be considered as the best treatment for this population...
  25. ncbi request reprint Fatal Loeffler's endocarditis due to hypereosinophilic syndrome
    Bo H Chao
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
    Am J Hematol 82:920-3. 2007
    ..HES is a potentially fatal disease with less than 50% reported 10-year survival. This case presentation is unusual in its rapidly progressive course leading to sudden death...
  26. ncbi request reprint A high-volume specialist palliative care unit and team may reduce in-hospital end-of-life care costs
    Thomas J Smith
    Virginia Commonwealth University Massey Cancer Center, and Medical College of Virginia Hospitals, Richmond, Virginia 23298 0230, USA
    J Palliat Med 6:699-705. 2003
    ..Current end-of-life hospital care can be of poor quality and high cost. High volume and/or specialist care, and standardized care with clinical practice guidelines, has improved outcomes and costs in other areas of cancer care...
  27. ncbi request reprint Tell it like it is
    Thomas J Smith
    Medical College of Virginia, Division of Hematology Oncology, Department of Internal Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    J Clin Oncol 21:12s-16s. 2003
  28. ncbi request reprint Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival
    Thomas J Smith
    Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298, USA
    J Clin Oncol 20:4040-9. 2002
    ..Implantable intrathecal drug delivery systems (IDDSs) have been used to manage refractory cancer pain, but there are no randomized clinical trial (RCT) data comparing them with comprehensive medical management (CMM)...
  29. ncbi request reprint Use of an implantable drug delivery system for refractory chronic sickle cell pain
    Thomas J Smith
    VCU Sickle Cell Anemia Program and Thomas Palliative Care Unit of Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Am J Hematol 78:153-4. 2005
    ..IDDS may offer relief for sickle cell patients with refractory pain. A prospective trial with more participants is planned...
  30. pmc Using claims-based measures to predict performance status score in patients with lung cancer
    Ramzi G Salloum
    Center for Health Services Research, Henry Ford Health System, Detroit, Michigan, USA R01 CA 114204 03, USA
    Cancer 117:1038-48. 2011
    ..To the authors' knowledge, no attempts have been made to estimate PS using claims-based measures. The current study explored the ability to estimate PS using routinely available measures...
  31. ncbi request reprint Palliative care and oncology partnerships in real practice
    Erin R Alesi
    Thomas Palliative Care Program, Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 25:1287-90, 1292-3. 2011
    ..As the benefits of integrating PC into oncology practice continue to be realized, more data will become available...
  32. doi request reprint Epoprostenol use for pulmonary arterial hypertension in the palliative care setting
    Colin P Wozencraft
    Department of Internal Medicine, Division of General Medicine, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    J Palliat Med 15:619-22. 2012
    ..We herein report our experience using epoprostenol in a dedicated palliative care unit and present our inpatient protocol for the drug's administration...
  33. doi request reprint Allocating cancer-directed expenditures: tensions between prevention, early detection and treatment is unnecessary
    Bruce E Hillner
    Department of Internal Medicine and the Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0170, USA
    Recent Results Cancer Res 188:1-9. 2011
    ..Changing behaviors, incentives, expectations, and the framing of treatment effects are necessary to "bend" the current unrelenting cancer care cost curve...
  34. doi request reprint Explaining marginal benefits to patients, when "marginal" means additional but not necessarily small
    Thomas J Smith
    Division of Hematology Oncology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA
    Clin Cancer Res 16:5981-6. 2010
    ..These difficult conversations can be done if the oncologist has the right medical information, the right script, and some decision aids...
  35. ncbi request reprint Nonclinical outcomes of hospital-based palliative care
    Kenneth R White
    Graduate Program in Health Administration, Department of Health Administration, Virginia Commonwealth University, Richmond, Virginia, USA
    J Healthc Manag 51:260-73; discussion 273-4. 2006
    ..This study highlights the nonclinical outcomes of one institution's inpatient PCU and provides guidelines for healthcare executives and managers to use in making decisions about adopting such programs...
  36. ncbi request reprint Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer
    Robin Matsuyama
    Massey Cancer Center of Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 24:3490-6. 2006
    ..We sought to determine the available sources of knowledge, the choices, and concerns of actual patients, and how patients balanced competing issues...
  37. ncbi request reprint Implantable drug delivery systems (IDDS) after failure of comprehensive medical management (CMM) can palliate symptoms in the most refractory cancer pain patients
    Thomas J Smith
    Thomas Palliative Care Unit, Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    J Palliat Med 8:736-42. 2005
    ..The objective of this study was to evaluate whether IDDS could help the most refractory patients failed by expert CMM...
  38. doi request reprint Clinical and financial impact of a palliative care program at a small rural hospital
    J Brian Cassel
    Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA
    J Palliat Med 13:1339-43. 2010
    ..This study reports the clinical and financial impact of a new palliative care service at a 76-bed nonprofit hospital located in rural Virginia, Rappahannock General Hospital (RGH)...
  39. doi request reprint Pilot trial of a patient-specific cutaneous electrostimulation device (MC5-A CalmareĀ®) for chemotherapy-induced peripheral neuropathy
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA
    J Pain Symptom Manage 40:883-91. 2010
    ..To date, there is no effective prevention or therapy. An evolving hypothesis for reducing CIPN pain involves direct nerve stimulation to reduce the pain impulse...
  40. doi request reprint A case of inaccurate prognostication after the ARCTIC protocol
    Christina J Chen
    Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA
    J Pain Symptom Manage 43:1120-5. 2012
    ....
  41. doi request reprint Intrathoracic malignant peripheral nerve sheath tumor in neurofibromatosis 1
    Bo H Chao
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    J Clin Oncol 26:2216-8. 2008
  42. pmc Cultural perceptions in cancer care among African-American and Caucasian patients
    Robin K Matsuyama
    Social and Behavioral Health, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0149, USA
    J Natl Med Assoc 99:1113-8. 2007
    ..This exploratory study examined perceptions and beliefs of African Americans and Caucasians related to cancer care. Understanding belief systems and cultures optimizes cancer treatment and care delivery to ethnic minority individuals...
  43. pmc Physicians' current practices and opportunities for DNA banking of dying patients with cancer
    John M Quillin
    Department of Human and Molecular Genetics, Department of Social and Behavioral Health, and Department of Medicine, Massey Cancer Center, Commonwealth University, Richmond, VA
    J Oncol Pract 7:183-7. 2011
    ..This study explored the current practices and potential for DNA banking for cancer susceptibility among oncologists specializing in palliative care...
  44. doi request reprint Dexmedetomidine: exploring its potential role and dosing guideline for its use in intractable pain in the palliative care setting
    Patrick J Coyne
    Thomas Palliative Care Program, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia, USA
    J Pain Palliat Care Pharmacother 24:384-6. 2010
    ..The authors offer criteria to consider in utilizing this medication within the context of palliative care...
  45. pmc Difficult cases of pain and nonpain symptoms in intractable spinal infections: a case series
    Molly L Olsen
    Department of Medicine, Mayo Clinic, Rochester, MN, USA
    Am J Hosp Palliat Care 29:493-6. 2012
    ..Furthermore, each case presented challenges regarding optimal medical management of somatic and neuropathic pain associated with the SI...
  46. pmc Historical estimation of diesel exhaust exposure in a cohort study of U.S. railroad workers and lung cancer
    Francine Laden
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Cancer Causes Control 17:911-9. 2006
    ..In conclusion, although precise historical estimates of exposure are not available, weighting factors helped better define the exposure-response relationship of diesel exhaust with lung cancer mortality...
  47. ncbi request reprint American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting
    James L Khatcheressian
    Virginia Commonwealth University Massey Cancer Center, Richmond, VA, USA
    J Clin Oncol 24:5091-7. 2006
    ..To update the 1999 American Society of Clinical Oncology (ASCO) guideline on breast cancer follow-up and management in the adjuvant setting...
  48. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Pain Headache Rep 9:243-8. 2005
    ..Given multiple positive small cohort studies and a positive high-power randomized trial, IDDS should be considered as the best treatment for this population...
  49. ncbi request reprint Massive hydromorphone dose delivered subcutaneously instead of intrathecally: guidelines for prevention and management of opioid, local anesthetic, and clonidine overdose
    Patrick J Coyne
    Virginia Commonwealth University Health System, School of Pharmacy, Richmond, Virginia 23298, USA
    J Pain Symptom Manage 28:273-6. 2004
    ..Counteracting an opioid with naloxone until the opioid is metabolized and excreted can be done safely. Inadvertent subcutaneous administration of other types of drugs could be more difficult to manage...
  50. ncbi request reprint The health economics of palliative care
    S Kirk Payne
    Palliative Care Service, Medical College of Virginia Hospitals and Massey Cancer Center, Virginia Commonwealth University, Richmond 23298 0230, USA
    Oncology (Williston Park) 16:801-8; discussion 808, 811-2. 2002
    ..One model is coordinated, expert, high-volume care that can prevent end-of-life hospitalization, with early use of advance directives. Preliminary data from our program support the hypothesis that costs may be reduced by 40% to 70%...
  51. ncbi request reprint Nebulized fentanyl citrate improves patients' perception of breathing, respiratory rate, and oxygen saturation in dyspnea
    Patrick J Coyne
    Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA
    J Pain Symptom Manage 23:157-60. 2002
    ..This inexpensive and readily available treatment may offer substantial relief of end-of-life dyspnea. Randomized trials, dose, and length of effect trials are underway...