T J Smith

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi request reprint Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival
    Thomas J Smith
    Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298, USA
    J Clin Oncol 20:4040-9. 2002
  2. ncbi request reprint Ensuring quality cancer care by the use of clinical practice guidelines and critical pathways
    T J Smith
    Massey Cancer Center, Division of Hematology Oncology, Department of Medicine, Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 19:2886-97. 2001
  3. ncbi request reprint How to use implantable intrathecal drug delivery systems for refractory cancer pain
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University Health System, Richmond, Virginia 23298 0230, USA
    J Support Oncol 1:73-6. 2003
  4. ncbi request reprint Tell it like it is
    Thomas J Smith
    Medical College of Virginia, Division of Hematology Oncology, Department of Internal Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    J Clin Oncol 21:12s-16s. 2003
  5. ncbi request reprint Implantable drug delivery systems (IDDS) after failure of comprehensive medical management (CMM) can palliate symptoms in the most refractory cancer pain patients
    Thomas J Smith
    Thomas Palliative Care Unit, Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    J Palliat Med 8:736-42. 2005
  6. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Pain Headache Rep 9:243-8. 2005
  7. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Oncol Rep 6:291-6. 2004
  8. ncbi request reprint An implantable drug delivery system (IDDS) for refractory cancer pain provides sustained pain control, less drug-related toxicity, and possibly better survival compared with comprehensive medical management (CMM)
    T J Smith
    Massey Cancer Center of Virginia Commonwealth University and other institutions, Richmond, VA 23298, USA
    Ann Oncol 16:825-33. 2005
  9. ncbi request reprint Use of an implantable drug delivery system for refractory chronic sickle cell pain
    Thomas J Smith
    VCU Sickle Cell Anemia Program and Thomas Palliative Care Unit of Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Am J Hematol 78:153-4. 2005
  10. ncbi request reprint Why academic divisions of hematology/oncology are in trouble and some suggestions for resolution
    T J Smith
    Division of Hematology Oncology, Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 19:260-4. 2001

Detail Information

Publications77

  1. ncbi request reprint Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival
    Thomas J Smith
    Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298, USA
    J Clin Oncol 20:4040-9. 2002
    ..Implantable intrathecal drug delivery systems (IDDSs) have been used to manage refractory cancer pain, but there are no randomized clinical trial (RCT) data comparing them with comprehensive medical management (CMM)...
  2. ncbi request reprint Ensuring quality cancer care by the use of clinical practice guidelines and critical pathways
    T J Smith
    Massey Cancer Center, Division of Hematology Oncology, Department of Medicine, Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 19:2886-97. 2001
    ..We describe the impact of clinical practice guidelines (CPGs) on improvement in oncology treatment processes or outcomes...
  3. ncbi request reprint How to use implantable intrathecal drug delivery systems for refractory cancer pain
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University Health System, Richmond, Virginia 23298 0230, USA
    J Support Oncol 1:73-6. 2003
  4. ncbi request reprint Tell it like it is
    Thomas J Smith
    Medical College of Virginia, Division of Hematology Oncology, Department of Internal Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    J Clin Oncol 21:12s-16s. 2003
  5. ncbi request reprint Implantable drug delivery systems (IDDS) after failure of comprehensive medical management (CMM) can palliate symptoms in the most refractory cancer pain patients
    Thomas J Smith
    Thomas Palliative Care Unit, Division of Hematology Oncology and Palliative Care, Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    J Palliat Med 8:736-42. 2005
    ..The objective of this study was to evaluate whether IDDS could help the most refractory patients failed by expert CMM...
  6. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Pain Headache Rep 9:243-8. 2005
    ..Given multiple positive small cohort studies and a positive high-power randomized trial, IDDS should be considered as the best treatment for this population...
  7. ncbi request reprint Pain management, including intrathecal pumps
    Thomas J Smith
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center of Virginia Commonwealth University, MCV Box 980230, Richmond, VA 23298 0230, USA
    Curr Oncol Rep 6:291-6. 2004
    ..Given multiple positive small cohort studies and a positive high-power randomized trial, IDDS should be considered as the best treatment for this population...
  8. ncbi request reprint An implantable drug delivery system (IDDS) for refractory cancer pain provides sustained pain control, less drug-related toxicity, and possibly better survival compared with comprehensive medical management (CMM)
    T J Smith
    Massey Cancer Center of Virginia Commonwealth University and other institutions, Richmond, VA 23298, USA
    Ann Oncol 16:825-33. 2005
    ..This 'as treated' analysis assessed if improvements in pain control, drug toxicity and survival were maintained over time...
  9. ncbi request reprint Use of an implantable drug delivery system for refractory chronic sickle cell pain
    Thomas J Smith
    VCU Sickle Cell Anemia Program and Thomas Palliative Care Unit of Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Am J Hematol 78:153-4. 2005
    ..IDDS may offer relief for sickle cell patients with refractory pain. A prospective trial with more participants is planned...
  10. ncbi request reprint Why academic divisions of hematology/oncology are in trouble and some suggestions for resolution
    T J Smith
    Division of Hematology Oncology, Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 19:260-4. 2001
    ..Academic divisions of hematology/oncology seem to have difficulty recruiting and retaining excellent productive clinicians. A major reason for this is that salaries do not compete with the private sector for similar work...
  11. ncbi request reprint Future strategies needed for palliative care
    T J Smith
    Division of Hematology Oncology, Departments of Medicine and Health Administration, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    Semin Radiat Oncol 10:254-61. 2000
    ..Cost constraints will lead to more gaps between the haves and have nots in the United States in the next 5 years...
  12. ncbi request reprint Costs of care associated with non-small-cell lung cancer in a commercially insured cohort
    B E Hillner
    Department of Internal Medicine, Medical College of Virginia and Massey Cancer Center, Virginia Commonwealth University, Richmond 23298 0170, USA
    J Clin Oncol 16:1420-4. 1998
    ..To examine the cost of incident cases of non-small-cell lung cancer (NSCLC) in a commercially insured cohort...
  13. ncbi request reprint Measuring standards of care for early breast cancer in an insured population
    B E Hillner
    Department of Internal Medicine, Medical College of Virginia, Richmond 23298, USA
    J Clin Oncol 15:1401-8. 1997
    ..To demonstrate the use of a combined data base to evaluate the care for local/regional invasive breast cancer in a large insured population of women aged less than 64 years...
  14. ncbi request reprint Pamidronate in prevention of bone complications in metastatic breast cancer: a cost-effectiveness analysis
    B E Hillner
    Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA
    J Clin Oncol 18:72-9. 2000
    ..We conducted a post-hoc evaluation of the cost-effectiveness of pamidronate using the results of two randomized trials that evaluated pamidronate 90 mg administered intravenously every month versus placebo...
  15. ncbi request reprint Economic analysis of a randomized clinical trial to compare filgrastim-mobilized peripheral-blood progenitor-cell transplantation and autologous bone marrow transplantation in patients with Hodgkin's and non-Hodgkin's lymphoma
    T J Smith
    Virginia Commonwealth University, Massey Cancer Center, Richmond 23298 0037, USA
    J Clin Oncol 15:5-10. 1997
    ..This study was undertaken to analyze the costs of the two strategies using prospectively collected data from a randomized clinical trial that compared filgrastim-mobilized PBPCT versus ABMT...
  16. ncbi request reprint Hospital and physician volume or specialization and outcomes in cancer treatment: importance in quality of cancer care
    B E Hillner
    Massey Cancer Center and Department of Internal Medicine, Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23298 0170, USA
    J Clin Oncol 18:2327-40. 2000
    ..To conduct a comprehensive review of the health services literature to search for evidence that hospital or physician volume or specialty affects the outcome of cancer care...
  17. ncbi request reprint Principles of cost effectiveness analysis for the assessment of current and new therapies
    B E Hillner
    Massey Cancer Center, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298
    J Hematother 2:501-6. 1993
    ....
  18. ncbi request reprint Improving palliative and supportive care in cancer patients
    James Khatcheressian
    Division of Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0230, USA
    Oncology (Williston Park) 19:1365-76; discussion 1377-8, 1381-2, 1384 passim. 2005
    ..Finally, we suggest a practical plan for using symptom assessment scales, listing the problems, and managing them according to algorithms or other predetermined plans...
  19. doi request reprint Concrete options and ideas for increasing value in oncology care: the view from one trench
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University Health System, Richmond, Virginia, USA
    Oncologist 15:65-72. 2010
    ..These actions will likely control costs, but in the short term will cause significant distress among patients, families, and health care practitioners...
  20. ncbi request reprint Tamoxifen should be cost-effective in reducing breast cancer risk in high-risk women
    T J Smith
    Department of Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA
    J Clin Oncol 18:284-6. 2000
    ..To estimate the cost-effectiveness of tamoxifen in the prevention of breast cancer...
  21. ncbi request reprint Economic analysis of adjuvant interferon alfa-2b in high-risk melanoma based on projections from Eastern Cooperative Oncology Group 1684
    B E Hillner
    Department of Internal Medicine and the Massey Cancer Center, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298, USA
    J Clin Oncol 15:2351-8. 1997
    ....
  22. ncbi request reprint Accelerated superfractionated radiotherapy for inflammatory breast carcinoma: complete response predicts outcome and allows for breast conservation
    D W Arthur
    Department of Radiation Oncology, Medical College of Virginia Hospitals of Virginia Commonwealth University VCU, Richmond 23298 0058, USA
    Int J Radiat Oncol Biol Phys 44:289-96. 1999
    ..The efficacy, failure patterns, and patient tolerance utilizing this approach were analyzed...
  23. ncbi request reprint Percutaneous liver biopsy in adult haemophiliacs with hepatitis C virus: safety of outpatient procedure and impact of human immunodeficiency virus coinfection on the spectrum of liver disease
    R K Sterling
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University Health System, Richmond, VA 23298, USA
    Haemophilia 13:164-71. 2007
    ..These data support the hypothesis that HIV accelerates fibrosis progression in those coinfected with HCV and highlights the importance of liver histology in this population...
  24. doi request reprint Barriers to effective palliative care for low-income patients in late stages of cancer: report of a study and strategies for defining and conquering the barriers
    Laurie J Lyckholm
    Division of Hematology Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University School of Medicine, PO Box 980230, Richmond, VA 23298 0230, USA
    Nurs Clin North Am 45:399-409. 2010
    ....
  25. pmc Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives
    Lindsay A Dow
    School of Medicine and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 28:299-304. 2010
    ..Ten years ago, patients with cancer said they would not like to discuss ADs with their oncologist but would be willing to discuss them with an admitting physician. We assessed whether this point of view still held...
  26. doi request reprint Palliative care consultation and hospital length of stay
    J Brian Cassel
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0037, USA
    J Palliat Med 13:761-7. 2010
    ....
  27. pmc Cultural perceptions in cancer care among African-American and Caucasian patients
    Robin K Matsuyama
    Social and Behavioral Health, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298 0149, USA
    J Natl Med Assoc 99:1113-8. 2007
    ..This exploratory study examined perceptions and beliefs of African Americans and Caucasians related to cancer care. Understanding belief systems and cultures optimizes cancer treatment and care delivery to ethnic minority individuals...
  28. ncbi request reprint Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer
    Robin Matsuyama
    Massey Cancer Center of Virginia Commonwealth University, Richmond, VA 23298 0230, USA
    J Clin Oncol 24:3490-6. 2006
    ..We sought to determine the available sources of knowledge, the choices, and concerns of actual patients, and how patients balanced competing issues...
  29. ncbi request reprint Nonclinical outcomes of hospital-based palliative care
    Kenneth R White
    Graduate Program in Health Administration, Department of Health Administration, Virginia Commonwealth University, Richmond, Virginia, USA
    J Healthc Manag 51:260-73; discussion 273-4. 2006
    ..This study highlights the nonclinical outcomes of one institution's inpatient PCU and provides guidelines for healthcare executives and managers to use in making decisions about adopting such programs...
  30. doi request reprint Cost and non-clinical outcomes of palliative care
    Thomas J Smith
    Department of Medicine, Virginia Commonwealth University, Massey Cancer Center, Richmond, Virginia, USA
    J Pain Symptom Manage 38:32-44. 2009
    ..In collecting and presenting the data to administrators and others, we have found that the simplest approach is the most effective-for example, presenting a few clinical outcomes alongside cost-saving data...
  31. ncbi request reprint Palliative care consultation in the process of organ donation after cardiac death
    Catherine McVearry Kelso
    Department of Internal Medicine, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23298, USA
    J Palliat Med 10:118-26. 2007
    ....
  32. ncbi request reprint Fatal Loeffler's endocarditis due to hypereosinophilic syndrome
    Bo H Chao
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
    Am J Hematol 82:920-3. 2007
    ..HES is a potentially fatal disease with less than 50% reported 10-year survival. This case presentation is unusual in its rapidly progressive course leading to sudden death...
  33. ncbi request reprint Identifying supportive and unsupportive responses of others: perspectives of African American and Caucasian cancer patients
    Christina M Grange
    Department of Psychology, Virginia Commonwealth University VCU, 808 W Franklin St, Box 842018, Richmond, VA, 23284, USA
    J Psychosoc Oncol 26:81-99. 2008
    ....
  34. ncbi request reprint A high-volume specialist palliative care unit and team may reduce in-hospital end-of-life care costs
    Thomas J Smith
    Virginia Commonwealth University Massey Cancer Center, and Medical College of Virginia Hospitals, Richmond, Virginia 23298 0230, USA
    J Palliat Med 6:699-705. 2003
    ..Current end-of-life hospital care can be of poor quality and high cost. High volume and/or specialist care, and standardized care with clinical practice guidelines, has improved outcomes and costs in other areas of cancer care...
  35. ncbi request reprint A comparison of patterns of care of nonsmall cell lung carcinoma patients in a younger and Medigap commercially insured cohort
    B E Hillner
    Department of Internal Medicine, Medical College of Virginia and the Massey Cancer Center, Virginia Commonwealth University, Richmond, USA
    Cancer 83:1930-7. 1998
    ..Commercial health care claims supplemented by clinical staging from cancer registries can address long term practice patterns in patients with cancer...
  36. ncbi request reprint Palliative care in BMT
    H M Chung
    Department of Internal Medicine, Division of Hematology Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA
    Bone Marrow Transplant 43:265-73. 2009
    ..This paper reports on the lack of literature available on palliative care into the BMT and explores areas of future research in the integration of these two fields of medicine...
  37. ncbi request reprint Ethics of rural health care
    L J Lyckholm
    Department of Medicine and the Division of Hematology/Oncology, Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0037, USA
    Crit Rev Oncol Hematol 40:131-8. 2001
    ..The academic center has provided expertise and continued education for staff, both individually and within groups, regarding ethical dilemmas...
  38. doi request reprint Genetics assessment at the end of life: suggestions for implementation in clinic and future research
    John Martin Quillin
    Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0033, USA
    J Palliat Med 11:451-8. 2008
    ..Once the patient has died, the chance to test or bank DNA for common inherited conditions such as breast cancer, colon cancer, cardiovascular disease, etc., is gone...
  39. pmc The role of chemotherapy at the end of life: "when is enough, enough?"
    Sarah Elizabeth Harrington
    Department of Internal Medicine and the Thomas Palliative Care Program, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA
    JAMA 299:2667-78. 2008
    ..Approaches to communication about prognosis and treatment options and questions that patients may want to ask are discussed...
  40. ncbi request reprint 'Futile care': what to do when your patient insists on chemotherapy that likely won't help
    James Khatcheressian
    Division of Hematology Oncology, Massey Cancer Center of Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 22:881-8; discussion 893, 896, 898. 2008
    ..In this review, we consider the roles of both the patient and the physician in driving the provision of "futile care" and offer practical steps the oncologist can take to avoid it...
  41. ncbi request reprint Giving honest information to patients with advanced cancer maintains hope
    Thomas J Smith
    Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA
    Oncology (Williston Park) 24:521-5. 2010
    ..One of the primary reasons stated for witholding this information is to "not take away hope." We could find no study that tested if hope was influenced by honest clinical information...
  42. ncbi request reprint Massive hydromorphone dose delivered subcutaneously instead of intrathecally: guidelines for prevention and management of opioid, local anesthetic, and clonidine overdose
    Patrick J Coyne
    Virginia Commonwealth University Health System, School of Pharmacy, Richmond, Virginia 23298, USA
    J Pain Symptom Manage 28:273-6. 2004
    ..Counteracting an opioid with naloxone until the opioid is metabolized and excreted can be done safely. Inadvertent subcutaneous administration of other types of drugs could be more difficult to manage...
  43. ncbi request reprint The health economics of palliative care
    S Kirk Payne
    Palliative Care Service, Medical College of Virginia Hospitals and Massey Cancer Center, Virginia Commonwealth University, Richmond 23298 0230, USA
    Oncology (Williston Park) 16:801-8; discussion 808, 811-2. 2002
    ..One model is coordinated, expert, high-volume care that can prevent end-of-life hospitalization, with early use of advance directives. Preliminary data from our program support the hypothesis that costs may be reduced by 40% to 70%...
  44. doi request reprint Intrathoracic malignant peripheral nerve sheath tumor in neurofibromatosis 1
    Bo H Chao
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    J Clin Oncol 26:2216-8. 2008
  45. ncbi request reprint American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting
    James L Khatcheressian
    Virginia Commonwealth University Massey Cancer Center, Richmond, VA, USA
    J Clin Oncol 24:5091-7. 2006
    ..To update the 1999 American Society of Clinical Oncology (ASCO) guideline on breast cancer follow-up and management in the adjuvant setting...
  46. ncbi request reprint Nebulized fentanyl citrate improves patients' perception of breathing, respiratory rate, and oxygen saturation in dyspnea
    Patrick J Coyne
    Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA
    J Pain Symptom Manage 23:157-60. 2002
    ..This inexpensive and readily available treatment may offer substantial relief of end-of-life dyspnea. Randomized trials, dose, and length of effect trials are underway...
  47. pmc Historical estimation of diesel exhaust exposure in a cohort study of U.S. railroad workers and lung cancer
    Francine Laden
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Cancer Causes Control 17:911-9. 2006
    ..In conclusion, although precise historical estimates of exposure are not available, weighting factors helped better define the exposure-response relationship of diesel exhaust with lung cancer mortality...
  48. ncbi request reprint Symptom-oriented follow-up of early breast cancer - as good as conventional control and sparing resources
    James Khatcheressian
    Onkologie 30:410-2. 2007
  49. ncbi request reprint Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline
    D Andrew Loblaw
    American Society of Clinical Oncology, Alexandria, VA 22314, USA
    J Clin Oncol 25:1596-605. 2007
    ..To update the 2004 American Society of Clinical Oncology (ASCO) guideline on initial hormonal management of androgen-sensitive, metastatic, recurrent, or progressive prostate cancer (PCa)...
  50. ncbi request reprint 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline
    Thomas J Smith
    American Society of Clinical Oncology, Cancer Policy and Clinical Affairs, Alexandria, VA 22314, USA
    J Clin Oncol 24:3187-205. 2006
    ..Guided by the 1996 ASCO clinical outcomes criteria, the Update Committee formulated recommendations based on improvements in survival, quality of life, toxicity reduction and cost-effectiveness...
  51. doi request reprint SPIKE$: a six-step protocol for delivering bad news about the cost of medical care
    Joshua McFarlane
    Department of Hematology Oncology, University of Tennessee, Knoxville, TN, USA
    J Clin Oncol 26:4200-4. 2008
  52. pmc Assessment of diesel particulate matter exposure in the workplace: freight terminals
    Rebecca J Sheesley
    Environmental Chemistry and Technology Program, University of Wisconsin, 660 N Park St, Madison, WI 53706, USA
    J Environ Monit 10:305-14. 2008
    ..4 +/- 9.5% for the terminal yard samples. A relatively consistent mobile source impact was present at all the terminals only when considering percentage of total OC concentrations, not in terms of absolute concentrations...
  53. pmc Vehicle traffic as a source of particulate polycyclic aromatic hydrocarbon exposure in the Mexico City metropolitan area
    Linsey C Marr
    Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Environ Sci Technol 38:2584-92. 2004
    ..These results indicate that exposure to vehicle-related PAH emissions on Mexico City's roadways may present an important public health risk...
  54. ncbi request reprint The association between personal measurements of environmental exposure to particulates and heart rate variability
    Shannon R Magari
    Occupational Health Program, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 13:305-10. 2002
    ..This may occur through changes in the cardiac autonomic nervous system, witnessed by changes in heart rate variability...
  55. ncbi request reprint American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer
    D Andrew Loblaw
    Cancer Policy and Clinical Affairs, 1900 Duke St, Suite 200, Alexandria, VA 22314, USA
    J Clin Oncol 22:2927-41. 2004
    ..The focus of this document is on the use, combinations, and timing of various forms of androgen deprivation therapy (ADT) for the palliation of men with androgen-sensitive disease...
  56. pmc Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study
    Pradeep Rajan
    Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    Am J Epidemiol 166:1400-8. 2007
    ..004). These results augment evidence of a deleterious association between lead and psychiatric symptoms...
  57. pmc Association of the blood/air partition coefficient of 1,3-butadiene with blood lipids and albumin
    Yu Sheng Lin
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Environ Health Perspect 110:165-8. 2002
    ....
  58. ncbi request reprint Nebulized lidocaine for intractable cough near the end of life
    Brian M Lingerfelt
    J Support Oncol 5:301-2. 2007
  59. ncbi request reprint Parental exposure to organic solvents and reduced birth weight
    Eunhee Ha
    Department of Preventive Medicine, Ewha Woman s Medical University, Seoul, South Korea
    Arch Environ Health 57:207-14. 2002
    ..Maternal exposure to organic solvents was associated with reduced birth weight in this population, but paternal exposure to organic solvents was not similarly associated...
  60. pmc Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions
    Kathleen M McCarty
    Department of Epidemiology and Public Health, Division of Environmental Health Sciences, Yale University School of Medicine, Epidemiology and Public Health, New Haven, CT, 06520 USA
    Carcinogenesis 28:1697-702. 2007
    ....
  61. pmc Lung cancer in railroad workers exposed to diesel exhaust
    Eric Garshick
    Pulmonary and Critical Care Medicine Section, Medical Service, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    Environ Health Perspect 112:1539-43. 2004
    ..Key words: diesel exhaust, lung cancer, occupational exposure...
  62. ncbi request reprint Estimation of personal exposures to particulate matter and metals in boiler overhaul work
    Youcheng Liu
    Department of Environmental Health, Harvard University School of Public Health, Boston, Massachusetts, USA corrected
    J Occup Environ Med 47:68-78. 2005
    ..We sought to develop an algorithm and estimate unmeasured exposures to particulate matter (PM) and metals in an epidemiologic study of boilermakers...
  63. ncbi request reprint Determinants of airborne fiber size in the glass fiber production industry
    Margaret M Quinn
    Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts 01854, USA
    J Occup Environ Hyg 2:19-28. 2005
    ..The models developed here can be used to size-adjust historical fiber concentration measurements for use in epidemiologic studies of respiratory disease...
  64. ncbi request reprint Phase II study of cisplatin and 5-fluorouracil (PF) and mitomycin C, vincristine, cisplatin and 5-fluorouracil (MVPF) in patients with metastatic large bowel cancer: an Eastern Cooperative Oncology Group study (EST 1285)
    Kishan J Pandya
    University of Rochester Cancer Center, Rochester, NY 14642, USA
    Oncology 66:118-25. 2004
    ..To compare the efficacy and the toxicity of cisplatin and 5-fluorouracil (PF) and mitomycin C, vincristine, cisplatin and 5-fluorouracil (MVPF) in patients with metastatic large bowel cancer. Patients and..
  65. ncbi request reprint Exposure to fuel-oil ash and welding emissions during the overhaul of an oil-fired boiler
    Youcheng Liu
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    J Occup Environ Hyg 2:435-43. 2005
    ..Fuel-oil ash was a major contributor to boilermakers' exposure to PM(10) and metals. Vanadium concentrations sometimes exceeded the 2003 American Conference of Governmental Industrial Hygienists (ACGIH) threshold limit value...
  66. ncbi request reprint A nested case-control study of prostate cancer and atrazine exposure
    Patrick A Hessel
    Exponent, Wood Dale, IL 60191, USA
    J Occup Environ Med 46:379-85. 2004
    ..54; 95% confidence interval, 1.69-82.20). There was no association between atrazine exposure and prostate cancer when those with > or =1 test were compared. There was no evidence for an association between atrazine and prostate cancer...
  67. ncbi request reprint Historical cohort study of U.S. man-made vitreous fiber production workers IX: summary of 1992 mortality follow up and analysis of respiratory system cancer among female workers
    Roslyn A Stone
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
    J Occup Environ Med 46:55-67. 2004
    ..Some demographic subgroups appear to be at relatively increased risk of RSC...
  68. ncbi request reprint No association between residential exposure to petrochemicals and brain tumor risk
    Chu Ling Yu
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:3007-9. 2005
  69. ncbi request reprint Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care
    James L Khatcheressian
    J Clin Oncol 24:835-7. 2006
  70. ncbi request reprint Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure
    Chu Ling Yu
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 164:200-7. 2006
    ..54 (95 percent confidence interval: 1.14, 2.09). This study illustrates the utility of geographic information system tools for providing refined exposure estimates for residential exposure to petrochemical pollution...
  71. pmc Smoking imputation and lung cancer in railroad workers exposed to diesel exhaust
    Eric Garshick
    Pulmonary and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, MA 02132, USA
    Am J Ind Med 49:709-18. 2006
    ..An association between diesel exhaust exposure and lung cancer mortality in a large retrospective cohort study of US railroad workers has previously been reported. However, specific information regarding cigarette smoking was unavailable...
  72. ncbi request reprint Arsenic methylation and bladder cancer risk in Taiwan
    Yen Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 14:303-10. 2003
    ..In this study we investigated the relationship among arsenic methylation ability, CAE, and the risk of bladder cancer in a hospital-based case-control study in southwestern Taiwan...
  73. ncbi request reprint Arsenic methylation and skin cancer risk in southwestern Taiwan
    Yen Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J Occup Environ Med 45:241-8. 2003
    ..46-11.22) when compared to women. Subjects with low SMI and high CAE have a substantially increased risk of skin cancer. Males in all strata of arsenic exposure and methylation ability had a higher risk of skin cancer than women...
  74. ncbi request reprint Genetic polymorphism in p53 codon 72 and skin cancer in southwestern Taiwan
    Yen Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 38:201-11. 2003
    ..The risk of skin cancer is increased in individuals with the Pro/Pro genotype. Larger, confirmatory studies are needed to clarify the role of constitutional polymorphisms in p53 and skin cancer risk...
  75. ncbi request reprint Do the large benefits justify the large costs of adjuvant breast cancer trastuzumab?
    Bruce E Hillner
    J Clin Oncol 25:611-3. 2007
  76. ncbi request reprint Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues
    Celine Brochot
    INERIS, Institut National de l Environnement Industriel et des Risques, Unité de Toxicologie Expérimentale, Parc Alata BP2, 60550 Verneuil en Halatte, France
    Chem Biol Interact 167:168-83. 2007
    ....
  77. ncbi request reprint Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer
    Kevin S Hughes
    Avon Comprehensive Breast Evaluation Center, Breast Ovarian Cancer Genetics and Risk Assessment Program, Massachusetts General Hospital, Division of Surgical Oncology, Boston 02114, USA
    N Engl J Med 351:971-7. 2004
    ..In women 70 years of age or older who have early breast cancer, it is unclear whether lumpectomy plus tamoxifen is as effective as lumpectomy followed by tamoxifen plus radiation therapy...