Domenic A Sica


Affiliation: Virginia Commonwealth University
Country: USA


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    Sica D, Gehr T, Fernandez A. Risk-benefit ratio of angiotensin antagonists versus ACE inhibitors in end-stage renal disease. Drug Saf. 2000;22:350-60 pubmed
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    Sica D, Struthers A, Cushman W, Wood M, Banas J, Epstein M. Importance of potassium in cardiovascular disease. J Clin Hypertens (Greenwich). 2002;4:198-206 pubmed
    ..Because of the complexity of this topic, issues of hyperkalemia will be addressed in a forthcoming manuscript. ..
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    Sica D. Metolazone and its role in edema management. Congest Heart Fail. 2003;9:100-5 pubmed
    ..The temptation should be avoided to simply reduce the doses of either metolazone or the loop diuretic as a means to controlling an active diuresis. ..
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    Sica D. Minoxidil: an underused vasodilator for resistant or severe hypertension. J Clin Hypertens (Greenwich). 2004;6:283-7 pubmed
    ..There is, however, a place for minoxidil in the treatment of resistant hypertension especially in patients with advanced renal disease. ..
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    Sica D. Pharmacokinetics and pharmacodynamics of mineralocorticoid blocking agents and their effects on potassium homeostasis. Heart Fail Rev. 2005;10:23-9 pubmed
    ..This is more apt to occur with spironolactone due to the very long half-life of several of its active metabolites. ..
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    Sica D, Grubbs R. Transdermal clonidine: therapeutic considerations. J Clin Hypertens (Greenwich). 2005;7:558-62 pubmed
    ..The not infrequent development of a dermatitis, together with a substantially greater cost than oral clonidine, have been the major undoings for transdermal clonidine. ..
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    Sica D. Centrally acting antihypertensive agents: an update. J Clin Hypertens (Greenwich). 2007;9:399-405 pubmed
    ..Escalating doses of drugs in this class often give rise to salt and water retention, in which case diuretic therapy becomes a valuable adjunctive therapy...